المؤلفون: Hirsch, Jana A, Michael, Yvonne L, Moore, Kari A, Melly, Steven, Hughes, Timothy M, Hayden, Kathleen, Luchsinger, Jose A, Jimenez, Marcia P, James, Peter, Besser, Lilah M, Sánchez, Brisa, Roux, Ana V Diez

المصدر: BMJ Open. 12(11)

مصطلحات موضوعية: Public Health, Health Sciences, Clinical Research, Prevention, Cardiovascular, Neurodegenerative, Atherosclerosis, Acquired Cognitive Impairment, Basic Behavioral and Social Science, Dementia, Brain Disorders, Aging, Behavioral and Social Science, Alzheimer's Disease, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurosciences, 2.4 Surveillance and distribution, 2.3 Psychological, social and economic factors, Aetiology, Neurological, Quality Education, Humans, Aged, Prospective Studies, Cohort Studies, Residence Characteristics, Cognition, EPIDEMIOLOGY, GERIATRIC MEDICINE, SOCIAL MEDICINE, STATISTICS & RESEARCH METHODS, Clinical Sciences, Public Health and Health Services, Other Medical and Health Sciences, Biomedical and clinical sciences, Health sciences, Psychology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/378590n4Test

المؤلفون: Barbera, Mariagnese, Lehtisalo, Jenni, Perera, Dinithi, Aspö, Malin, Cross, Mary, De Jager Loots, Celeste A., Falaschetti, Emanuela, Friel, Naomi, Luchsinger, José A., Gavelin, Hanna Malmberg, Peltonen, Markku, Price, Geraint, Neely, Anna Stigsdotter, Thunborg, Charlotta, Tuomilehto, Jaakko, Mangialasche, Francesca, Middleton, Lefkos, Ngandu, Tiia, Solomon, Alina, Kivipelto, Miia

المساهمون: Clinicum, Department of Public Health, HUS Helsinki and Uusimaa Hospital District

مصطلحات موضوعية: Alzheimer’s, APOE, Cognitive impairment, Dementia prevention, Drug repurposing, Lifestyle intervention, Lifestyle-drug combination therapy, Metformin, World-Wide FINGERS, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: Open access funding provided by Karolinska Institute. The study is funded by grants from: Alzheimer’s Association – Part the Cloud Gates Partnership 2020 (PTC); Alzheimer’s Drug Discovery Foundation (ADDF); Alzheimerfonden (Sweden); Region Stockholm (ALF grant); European Research Council (ERC, 804371); EU Joint Programme—Neurodegenerative Disease Research (JPND) EURO-FINGERS and Multi-MeMo grants; ERA-NET Cofund Scheme—Horizon 2020 Research and Innovation Framework Programme of the European Commission Research Directorate-General (ERA PerMed grant); NordForsk NJ-FINGERS grant; Swedish Research Council; Region Stockholm (ALF, Sweden); Center for Innovative Medicine (CIMED) at Region Stockholm (Sweden); Stiftelsen Stockholms Sjukhem (Sweden); Swedish Research Council for Health, Working Life and Welfare; Hjärnfonden (Sweden); Academy of Finland. JAL is supported by the National Institutes of Health (United States) grant K24AG045334. Metformin (Glucophage XR/SR 500mg) has been provided by Merck Healthcare KGaA, Germany. The Finnish participants of the MET-FINGER study will be recruited through THL Biobank (study number THLBB2022_40). The MET-FINGER Study Team members are: Seliat Adebanke Adeleke, Clara Arvidsson, Malin Aspö, Mariagnese Barbera, Isobel Barton, Mehmet Bas, Katrina Cosby, Jennifer Crispin, Mary Cross, Celeste De Jager Loots, Lucy Dunn, Margarita Durkina, Ottilia Elebring, Emanuela Falaschetti, Naomi Friel, Jamie Ford, Parthenia Giannakopoulou, Hanne Gilkes, Hannah Graham, Göran Hagman, Ruby Hall, Helena Hallinder, Arzish Haqqee, Maris Hartmanis, Katri Hemiö, Zuzana Istvánfyová, Dimitra Kafetsouli, Miia Kivipelto, Kristina Lakey, Saara Lehtimäki, Jenni Lehtisalo, Lotta Lindström, Peter MacDonald, Aaro Mäkelä, Francesca Mangialasche, Stefan McGinn-Summers, Carolina Meius, Lefkos Middleton, Amnah Mirza, Tiia Ngandu, Christine Oesterling, Joanna Ojala, Abdulwarrith Olawale, Dinithi Perera, Geraint Price, Isabela Ramanath, Hanna-Maria Roitto, Bilal Sahib, Shonella Singh, Alina Solomon, Maria Sundell, Shannon Taylor, Devika Tharumaratnam, Charlotta Thunborg, Jaakko Tuomilehto, Kerttu Uusimäki, Johanna Vaarala, Heta Voutilainen, Jessica Åsander.; Barbera , M , Lehtisalo , J , Perera , D , Aspö , M , Cross , M , De Jager Loots , C A , Falaschetti , E , Friel , N , Luchsinger , J A , Gavelin , H M , Peltonen , M , Price , G , Neely , A S , Thunborg , C , Tuomilehto , J , Mangialasche , F , Middleton , L , Ngandu , T , Solomon , A & Kivipelto , M 2024 , ' A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability : the MET-FINGER randomised controlled trial protocol ' , Alzheimer's Research and Therapy , vol. 16 , no. 1 , 23 . https://doi.org/10.1186/s13195-023-01355-xTest; 85183664343; 85292b83-d53c-4e3a-8f86-607deb3120c1; http://hdl.handle.net/10138/571215Test; 001154328500002

الإتاحة: http://hdl.handle.net/10138/571215Test

المؤلفون: Gonzalez-Ortiz, Fernando, Kirsebom, Bjørn-Eivind, Contador, José, Tanley, Jordan E, Selnes, Per, Gísladóttir, Berglind, Pålhaugen, Lene, Suhr Hemminghyth, Mathilde, Jarholm, Jonas, Skogseth, Ragnhild, Bråthen, Geir, Grøndtvedt, Gøril, Bjørnerud, Atle, Tecelao, Sandra, Waterloo, Knut, Aarsland, Dag, Fernández-Lebrero, Aida, García-Escobar, Greta, Navalpotro-Gómez, Irene, Turton, Michael, Hesthamar, Agnes, Kac, Przemyslaw R, Nilsson, Johanna, Luchsinger, Jose, Hayden, Kathleen M, Harrison, Peter, Puig-Pijoan, Albert, Zetterberg, Henrik, Hughes, Timothy M, Suárez-Calvet, Marc, Karikari, Thomas K, Fladby, Tormod, Blennow, Kaj

المصدر: Nature Communications , 15 , Article 2908. (2024)

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10191157/1/s41467-024-47286-5.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10191157Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10191157/1/s41467-024-47286-5.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10191157Test/

المؤلفون: Luchsinger, José, Léger, Gabriel, Taylor, Curtis, Jacobs, Diane, Salmon, David, Edland, Steven, Messer, Karen, Revta, Carolyn, Flowers, Sarah, Jones, Kerry, Koulman, Albert, Yarasheski, Kevin, Verghese, Philip, Venkatesh, Venky, Zetterberg, Henrik, Durant, January, Lupo, Jody-Lynn, Gibson, Gary, Feldman, Howard

المصدر: PLoS ONE, vol 19, iss 5

مصطلحات موضوعية: Humans, Alzheimer Disease, Thiamine, Double-Blind Method, Male, Female, Aged, Middle Aged, Treatment Outcome, Prodrugs

وصف الملف: application/pdf

العلاقة: qt2010z42d; https://escholarship.org/uc/item/2010z42dTest

الإتاحة: https://escholarship.org/uc/item/2010z42dTest

المؤلفون: Hughes, Timothy M., Tanley, Jordan, Chen, Haiying, Schaich, Christopher L., Yeboah, Joseph, Espeland, Mark A., Lima, Joao A.C., Ambale-Venkatesh, Bharath, Michos, Erin D., Ding, Jingzhong, Hayden, Kathleen, Casanova, Ramon, Craft, Suzanne, Rapp, Stephen R., Luchsinger, José A., Fitzpatrick, Annette L., Heckbert, Susan R., Post, Wendy S., Burke, Gregory L.

المساهمون: National Center for Advancing Translational Sciences, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute

المصدر: Atherosclerosis ; volume 392, page 117521 ; ISSN 0021-9150

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1016/j.atherosclerosis.2024.117521Test
https://api.elsevier.com/content/article/PII:S0021915024000819?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021915024000819?httpAccept=text/plainTest

المؤلفون: Lucero, Robert J, Yoon, Sunmoo, Suero-Tejeda, Niurka, Arcia, Adriana, Iribarren, Sarah, Mittelman, Mary, Luchsinger, Jose, Bakken, Suzanne

المصدر: JAMIA Open. 5(1)

مصطلحات موضوعية: Health Services and Systems, Health Sciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Brain Disorders, Dementia, Aging, Behavioral and Social Science, Acquired Cognitive Impairment, Neurosciences, 7.1 Individual care needs, Management of diseases and conditions, caregivers, dementia, mobile health, persuasive systems design, self-management, Health services and systems

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/75r0397nTest

المؤلفون: Noble, James M., Manly, Jennifer J., Schupf, Nicole, Tang, Ming-Xing, Luchsinger, Jose´ A.

المصدر: Noble, James M. and Manly, Jennifer J. and Schupf, Nicole and Tang, Ming-Xing and Luchsinger, Jose´ A. (2012) Type 2 Diabetes and Ethnic Disparities in Cognitive Impairment. Ethnicity & Disease, 22 (1). pp. 38-44.

العلاقة: http://health-equity.pitt.edu/3805Test/

المؤلفون: Zou, James, Johnson, Aubrey, France, Jeanelle, Bharadwaj, Srinidhi, Tomljanovic, Zeljko, Stern, Yaakov, Brickman, Adam M., Devanand, Devangere P., Luchsinger, Jose A., Kreisl, William C., Provenzano, Frank A.

مصطلحات موضوعية: Quantitative Biology - Quantitative Methods, Electrical Engineering and Systems Science - Image and Video Processing

الوصول الحر: http://arxiv.org/abs/2010.07897Test

المؤلفون: Elfassy, Tali, Aiello, Allison E, Schneiderman, Neil, Haan, Mary N, Tarraf, Wassim, González, Hector M, Gellman, Marc, Florez, Hermes J, Luchsinger, Jose A, Wright, Clinton B, Grober, Ellen, Zeki Al Hazzouri, Adina

المصدر: Journal of aging and health. 31(7)

مصطلحات موضوعية: Humans, Diabetes Mellitus, Prevalence, Risk Factors, Cross-Sectional Studies, Cognition, Adult, Aged, Middle Aged, West Indies, Mexico, United States, South America, Female, Male, Hispanic or Latino, Hispanics/Latinos, cognitive aging, diabetes, epidemiology, minority aging, Nutrition, Clinical Research, Diabetes, Metabolic and endocrine, Hispanics, Latinos, Public Health and Health Services, Gerontology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2b19s4vbTest

المؤلفون: Moise, Nathalie, Wood, Dallas, Cheung, Ying Kuen K, Duan, Naihua, St. Onge, Tara, Duer-Hefele, Joan, Pu, Tiffany, Davidson, Karina W, Kronish, Ian M, Collaboratory”, The Members of the Personalized Trial, Alcantara, Carmela, Appelbaum, Paul, Carter, Eileen, Cohn, Elizabeth, Kravitz, Richard, Kelly, Scott, Luchsinger, Jose, Ridenour, Ty, Romandetto, Michele, Shaffer, Jonathan, Shea, Steven

مصطلحات موضوعية: Epidemiology, Health Sciences, Clinical Research, Comparative Effectiveness Research, Clinical Trials and Supportive Activities, Good Health and Well Being, Adult, Age Factors, Aged, Clinical Trials as Topic, Cross-Sectional Studies, Evidence-Based Medicine, Female, Health Expenditures, Humans, Logistic Models, Male, Middle Aged, Patient Preference, Precision Medicine, Socioeconomic Factors, Surveys and Questionnaires, Members of the “Personalized Trial Collaboratory”, Conjoint analysis, Discrete choice, Heterogeneity of treatment effects, Multi-morbidity, N-of-1 trials, Patient-centered care, Mathematical Sciences, Medical and Health Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/010768v0Test