المؤلفون: Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu, Timothy Y. Huang, Yingjun Zhao, Chengcheng Zhang, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An

المصدر: Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-28 (2022)

مصطلحات موضوعية: Alzheimer’s disease, TREM2, ITAM, Antibody, LILRB2, ITIM, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1750-1326Test

الوصول الحر: https://doaj.org/article/375488437204489ba10baa9354be3594Test

المؤلفون: Tongmei Zhang, Jessica Stupack, Huaxi Xu, Xiao-Peng Xiong, Lisa Zhou, Barbara Ranscht, Alex Campos, Elena B. Pasquale, William C. Mobley, Timothy Y. Huang, Lu-Lin Jiang

المصدر: J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 40, iss 31

مصطلحات موضوعية: Male, MAPK/ERK pathway, Aging, Neurodegenerative, Alzheimer's Disease, Medical and Health Sciences, Hippocampus, Transgenic, neurite regeneration, Mice, Epidermal growth factor, Receptors, 2.1 Biological and endogenous factors, Aetiology, Phosphorylation, Inbred BALB C, Cells, Cultured, Research Articles, Mice, Inbred BALB C, Cultured, Kinase, Chemistry, General Neuroscience, SORLA, Genes, fos, Cell biology, ErbB Receptors, ERK, Neurological, Female, Signal transduction, neurite outgrowth, Neurite, fos, MAP Kinase Signaling System, Cells, 1.1 Normal biological development and functioning, Mice, Transgenic, LDL, EGF receptor, Downregulation and upregulation, Underpinning research, Acquired Cognitive Impairment, Neurites, Animals, Transcription factor, Neurology & Neurosurgery, Psychology and Cognitive Sciences, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Membrane Transport Proteins, Brain Disorders, Nerve Regeneration, Genes, Gene Expression Regulation, Receptors, LDL, Dementia, soluble SORLA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8df7a3664e8b0609f7c4a454a31a12Test
https://doi.org/10.1523/jneurosci.0723-20.2020Test

المؤلفون: Don W. Cleveland, Amy Taylor, Albert R. La Spada, Clotilde Lagier-Tourenne, Jie Jiang, Tania F. Gendron, Sandra Diaz Garcia, Huaxi Xu, John Ravits, Somasish Ghosh Dastidar, Lu-Lin Jiang, Leonard Petrucelli, Melissa McAlonis-Downes, María José Cubillas Rodríguez, Patrick King, Sandrine Da Cruz, Qiang Zhu, Yong Jie Zhang

المصدر: Nature Neuroscience. 23:615-624

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, General Neuroscience, Transgene, Autophagy, Endogeny, Biology, medicine.disease, Cell biology, C9orf72 Protein, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, C9orf72, medicine, Amyotrophic lateral sclerosis, Trinucleotide repeat expansion, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b2f47b9547712e8316f32a36af9ad022Test
https://doi.org/10.1038/s41593-020-0619-5Test

المؤلفون: Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu, Timothy Y. Huang, Yingjun Zhao, Chengcheng Zhang, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An

المصدر: Molecular neurodegeneration. 17(1)

مصطلحات موضوعية: Membrane Glycoproteins, Induced Pluripotent Stem Cells, Brain, Plaque, Amyloid, Ligands, Cellular and Molecular Neuroscience, Mice, Alzheimer Disease, Animals, Humans, Neurology (clinical), Microglia, Receptors, Immunologic, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337ce753117af8b6e62f55546ade4f01Test
https://pubmed.ncbi.nlm.nih.gov/35717259Test

المؤلفون: Angus C. Nairn, Peng Xu, Jerry C. Chang, Eitan Wong, Wei Wang, Wenjie Luo, Michael Bamkole, Karima Bettayeb, Yue-Ming Li, Timothy Y. Huang, Lu-Lin Jiang, Marc Flajolet, Xiaopu Zhou, Huaxi Xu, Paul Greengard, Nancy Y. Ip

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Aging, Transcription, Genetic, Immunology, Nerve Tissue Proteins, Disease, Biology, Proteomics, Hippocampus, Models, Biological, Article, Biological pathway, Pathogenesis, 03 medical and health sciences, Amyloid beta-Protein Precursor, 0302 clinical medicine, Alzheimer Disease, Immunology and Allergy, Animals, Homeostasis, Humans, Protein phosphorylation, Phosphorylation, Cholesterol homeostasis, Mice, Knockout, Neurons, Base Sequence, Nuclear Proteins, Proteins, Lipid metabolism, Lipid Metabolism, Cell biology, Mitochondria, Mice, Inbred C57BL, Disease Models, Animal, Protein Transport, 030104 developmental biology, Mitochondrial Membranes, Open Field Test, 030217 neurology & neurosurgery, Function (biology), Neuroscience, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce044f0cc0397c910ea0c69561ca2f2dTest
http://europepmc.org/articles/PMC8222926Test

المؤلفون: Don W. Cleveland, Lu-Lin Jiang, Tongfei Liu, Wenxi Xu, Lisa Zhou, Huaxi Xu, Tao Long, Sandrine Da Cruz, María Jesús Delgado Rodríguez, Yingjun Zhao, Dongxian Zhang, Xiaoguang Li, Juan C. Piña-Crespo, Timothy Y. Huang, John Ravits, Bing Zhu, Haiyang Yu

المصدر: Journal of Clinical Investigation. 129:3103-3120

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Excitotoxicity, Down-Regulation, Glutamic Acid, Nerve Tissue Proteins, Biology, medicine.disease_cause, Mice, 03 medical and health sciences, Glutamatergic, 0302 clinical medicine, Downregulation and upregulation, Glutamate homeostasis, medicine, Animals, Humans, Amyotrophic lateral sclerosis, Mice, Knockout, Superoxide Dismutase, Amyotrophic Lateral Sclerosis, Neurodegeneration, Motor Cortex, Neurotoxicity, General Medicine, Motor neuron, medicine.disease, Up-Regulation, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Excitatory Amino Acid Transporter 2, Receptors, Tumor Necrosis Factor, Type I, Astrocytes, 030220 oncology & carcinogenesis, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c52e2b644cdba2e7459a8f8cb8a3d6aTest
https://doi.org/10.1172/jci127695Test

المؤلفون: Timothy Y. Huang, Paul Greengard, Yulin Li, Wenjie Luo, Xuemeng Zhou, Marc Flajolet, Peng Xu, Jerry C. Chang, Karima Bettayeb, Angus C. Nairn, Huaxi Xu, Nancy Y. Ip, Eitan Wong, Lu-Lin Jiang, Wei Wang, Michael Bamkole

مصطلحات موضوعية: Biological pathway, Pathogenesis, ER membrane, Protein phosphorylation, Lipid metabolism, Disease, Biology, Mitochondrion, Proteomics, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::18e1e72e132da9bef1587b28ca7b81a4Test
https://doi.org/10.1101/2020.11.17.385245Test

المؤلفون: Rudolph E. Tanzi, Huaxi Xu, Sara Brin Rosenthal, Mathew Blurton-Jones, Timothy Y. Huang, Amanda McQuade, Lu-Lin Jiang, Lisa Zhou, Tongfei Liu, Jun Yin, Yan Liu, Andrew Hodges, Bing Zhu, Xiaoguang Li, Xiaoming Zhang, Joel Yancey

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Proteome, Cellular differentiation, Immunology, SORL1, Human Embryonic Stem Cells, Transplantation, Heterologous, Mice, Transgenic, Biology, Models, Biological, Technical Advances and Resources, Cell Line, Epigenesis, Genetic, 03 medical and health sciences, 0302 clinical medicine, Apolipoproteins E, Phagocytosis, Neuroinflammation, Alzheimer Disease, Immunology and Allergy, Animals, Humans, INPP5D, Gene Regulatory Networks, Epigenetics, Gene, Genetics, Amyloid beta-Peptides, TREM2, Brain, Genetic Variation, Cell Differentiation, Chromatin, Up-Regulation, Transplantation, 030104 developmental biology, Genetic Loci, Gene Targeting, Mutation, Mutant Proteins, Microglia, Transcriptome, 030217 neurology & neurosurgery, Human Disease Genetics, Signal Transduction, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0db200a80eb055d6aca987b16cba07Test
https://pubmed.ncbi.nlm.nih.gov/32941599Test

المؤلفون: Thomas E. Willnow, Timothy Y. Huang, Eliezer Masliah, Yan Liu, Xiaoguang Li, Juan C. Piña-Crespo, Huaxi Xu, Yingjun Zhao, Bing Zhu, Elena B. Pasquale, Yu Sun, Lu-Lin Jiang

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Amyloid, Growth Cones, Long-Term Potentiation, Immunology, SORL1, Mice, Transgenic, Ligands, Article, Receptor tyrosine kinase, Amyloid beta-Protein Precursor, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Alzheimer Disease, medicine, Animals, Humans, Immunology and Allergy, Receptor, LDL-Receptor Related Proteins, Research Articles, Mice, Inbred BALB C, biology, Chemistry, Neurodegeneration, Receptor, EphA4, Membrane Transport Proteins, Long-term potentiation, medicine.disease, Cell biology, HEK293 Cells, 030104 developmental biology, Receptors, LDL, Mutation, Nerve Degeneration, Synapses, LDL receptor, biology.protein, Ephrins, 030217 neurology & neurosurgery, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cbbcea54f1d6c4d2a01e09608c3648Test
https://doi.org/10.1084/jem.20171413Test

المؤلفون: Zoltán Papp, Tibor Hortobágyi, Zoltán Fekécs, Zsuzsanna Kolostyak, James J. Hickman, Antal Nógrádi, Xiufang Guo, Laszlo Nagy, Attila Pap, Bálint Rehó, György Vámosi, Dorothee Dormann, Gerardo Alvarado Contreras, Katalin Karolyi, Attila Horvath, Lu Lin Jiang, Huaxi Xu, Krisztián Pajer, Miklós Antal, Tatiana Sieler, Greta Kiss, Andreas Patsalos, Zsolt Keresztessy, Zsanett Sári, Zoltan Simandi

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, Protein-Arginine N-Methyltransferases, Arginine, DNA Repair, DNA damage, Recombinant Fusion Proteins, Neuromuscular Junction, Mice, Transgenic, Biology, Neuroprotection, Cell Line, 03 medical and health sciences, Mice, Isometric Contraction, medicine, Animals, DNA Breaks, Double-Stranded, Amino Acid Sequence, RNA, Small Interfering, Cyclic AMP Response Element-Binding Protein, Research Articles, Protein arginine methyltransferase 8, Mice, Knockout, Motor Neurons, Muscle Cells, Reflex, Abnormal, General Neuroscience, Neurodegeneration, Methylation, medicine.disease, Cell biology, 030104 developmental biology, Spinal Cord, Rotarod Performance Test, biology.protein, RNA Interference, Signal transduction, CREB1, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc776efdc758edc2ca602d142b6c68cTest
https://europepmc.org/articles/PMC6113905Test/