يعرض 1 - 10 نتائج من 10 نتيجة بحث عن '"Liyanage, H. D. Sarath"', وقت الاستعلام: 0.96s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Reductive Metabolism Influences the Toxicity and Pharmacokinetics of the Hypoxia-Targeted Benzotriazine Di-Oxide Anticancer Agent SN30000 in Mice

    المؤلفون: Gu, Yongchuan, Chang, Tony T.-A., Wang, Jingli, Jaiswal, Jagdish K., Edwards, David, Downes, Noel J., Liyanage, H. D. Sarath, Lynch, Courtney R. H., Pruijn, Frederik B., Hickey, Anthony J. R., Hay, Michael P., Wilson, William R., Hicks, Kevin O.

    المساهمون: Health Research Council of New Zealand, Genesis Oncology Trust, Cancer Research UK

    المصدر: Frontiers in Pharmacology ; volume 8 ; ISSN 1663-9812

    مصطلحات موضوعية: Pharmacology (medical), Pharmacology

    الإتاحة: https://doi.org/10.3389/fphar.2017.00531Test

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  2. 2
    دورية أكاديمية
    Spatially-resolved pharmacokinetic/pharmacodynamic modelling of bystander effects of a nitrochloromethylbenzindoline hypoxia-activated prodrug

    المؤلفون: Hong, Cho Rong, Mehta, Sunali Y., Liyanage, H. D. Sarath, McManaway, Sarah P., Lee, Ho H., Jaiswal, Jagdish K., Bogle, Gib, Tercel, Moana, Pruijn, Frederik B., Wilson, William R., Hicks, Kevin O.

    المساهمون: Health Research Council of New Zealand, Cancer Society of New Zealand, Mary Manning Memorial Fellowship

    المصدر: Cancer Chemotherapy and Pharmacology ; volume 88, issue 4, page 673-687 ; ISSN 0344-5704 1432-0843

    مصطلحات موضوعية: Pharmacology (medical), Cancer Research, Pharmacology, Toxicology, Oncology

    الإتاحة: https://doi.org/10.1007/s00280-021-04320-3Test

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  3. 3
    دورية أكاديمية
    Influence of a Basic Side Chain on the Properties of Hypoxia-Selective Nitro Analogues of the Duocarmycins: Demonstration of Substantial Anticancer Activity in Combination with Irradiation or Chemotherapy

    المؤلفون: Tercel, Moana, Lee, Ho H., Mehta, Sunali Y., Youte Tendoung, Jean-Jacques, Bai, Sally Y., Liyanage, H. D. Sarath, Pruijn, Frederik B.

    المساهمون: Cancer Society of New Zealand, Health Research Council of New Zealand, Foundation for Research, Science and Technology

    المصدر: Journal of Medicinal Chemistry ; volume 60, issue 13, page 5834-5856 ; ISSN 0022-2623 1520-4804

    الإتاحة: https://doi.org/10.1021/acs.jmedchem.7b00563Test

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  4. 4
    دورية أكاديمية
    Mechanism of Action of AminoCBIs: Highly Reactive but Highly Cytotoxic Analogues of the Duocarmycins

    المؤلفون: Tercel, Moana, Pruijn, Frederik B., O'Connor, Patrick D., Liyanage, H. D. Sarath, Atwell, Graham J., Alix, Sonia M.

    المصدر: ChemBioChem ; volume 15, issue 13, page 1998-2006 ; ISSN 1439-4227 1439-7633

    الإتاحة: https://doi.org/10.1002/cbic.201402256Test

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  5. 5
    دورية أكاديمية
    Preparation and Properties of Clickable Amino Analogues of the Duocarmycins: Factors That Affect the Efficiency of Their Fluorescent Labelling of DNA

    المؤلفون: Tercel, Moana, McManaway, Sarah P., Liyanage, H. D. Sarath, Pruijn, Frederik B.

    المصدر: ChemMedChem ; volume 9, issue 9, page 2193-2206 ; ISSN 1860-7179 1860-7187

    الإتاحة: https://doi.org/10.1002/cmdc.201402169Test

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  6. 6
    دورية أكاديمية
    The Cytotoxicity of Duocarmycin Analogues is Mediated through Alkylation of DNA, not Aldehyde Dehydrogenase 1: A Comment

    المؤلفون: Tercel, Moana, McManaway, Sarah P., Leung, Euphemia, Liyanage, H. D. Sarath, Lu, Guo‐Liang, Pruijn, Frederik B.

    المصدر: Angewandte Chemie ; volume 125, issue 21, page 5552-5556 ; ISSN 0044-8249 1521-3757

    الإتاحة: https://doi.org/10.1002/ange.201208373Test

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  7. 7
    دورية أكاديمية
    Reductive Metabolism Influences the Toxicity and Pharmacokinetics of the Hypoxia-Targeted Benzotriazine Di-Oxide Anticancer Agent SN30000 in Mice.

    المؤلفون: Yongchuan Gu, Chang, Tony T.-A., Jingli Wang, Jaiswal, Jagdish K., Edwards, David, Downes, Noel J., Liyanage, H. D. Sarath, Lynch, Courtney R. H., Pruijn, Frederik B., Hickey, Anthony J. R., Hay, Michael P., Wilson, William R., Hicks, Kevin O.

    المصدر: Frontiers in Pharmacology; 8/11/2017, p1-16, 16p

    مصطلحات موضوعية: TRIAZINE derivatives, ANTINEOPLASTIC agents

    النص الكامل

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  8. 8
    دورية أكاديمية
    Preparation and Antitumour Properties of the Enantiomers of a Hypoxia‐Selective Nitro Analogue of the Duocarmycins

    المؤلفون: Tercel, Moana, Lee, Ho H., Yang, Shangjin, Liyanage, H. D. Sarath, Mehta, Sunali Y., Boyd, Peter D. W., Jaiswal, Jagdish K., Tan, Karin L., Pruijn, Frederik B.

    المصدر: ChemMedChem ; volume 6, issue 10, page 1860-1871 ; ISSN 1860-7179 1860-7187

    الإتاحة: https://doi.org/10.1002/cmdc.201100271Test

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  9. 9
    دورية أكاديمية
    Extravascular Transport of Drugs in Tumor Tissue: Effect of Lipophilicity on Diffusion of Tirapazamine Analogues in Multicellular Layer Cultures

    المؤلفون: Pruijn, Frederik B., Sturman, Joanna R., Liyanage, H. D. Sarath, Hicks, Kevin O., Hay, Michael P., Wilson, William R.

    المصدر: Journal of Medicinal Chemistry ; volume 48, issue 4, page 1079-1087 ; ISSN 0022-2623 1520-4804

    الإتاحة: https://doi.org/10.1021/jm049549pTest

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  10. 10
    دورية أكاديمية
    DNA-Targeted 1,2,4-Benzotriazine 1,4-Dioxides: Potent Analogues of the Hypoxia-Selective Cytotoxin Tirapazamine

    المؤلفون: Hay, Michael P., Pruijn, Frederik B., Gamage, Swarna A., Liyanage, H. D. Sarath, Kovacs, Mary S., Patterson, Adam V., Wilson, William R., Brown, J. Martin, Denny, William A.

    المصدر: Journal of Medicinal Chemistry ; volume 47, issue 2, page 475-488 ; ISSN 0022-2623 1520-4804

    الإتاحة: https://doi.org/10.1021/jm030399cTest

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