دورية أكاديمية
Selective Access to Functional Fluoroenones via Palladium-Catalyzed Selenofluoroalkylacylation of Terminal Alkynes
| العنوان: | Selective Access to Functional Fluoroenones via Palladium-Catalyzed Selenofluoroalkylacylation of Terminal Alkynes |
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| المؤلفون: | Ya Li, Dian Dong, Lintong Chen, Hongxuan Du, Cong Zhao, Xiaoyan Bai, Lu Chen, Yibiao Li, Xianghua Zeng, Pierre H. Dixneuf, Min Zhang |
| سنة النشر: | 1753 |
| مصطلحات موضوعية: | Biochemistry, Medicine, Microbiology, Inorganic Chemistry, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, polar crossover process, mechanistic studies reveal, alkyl disubstituted enones, reaction proceeds via, widely studied, terminal alkynes, selective access, oxidative radical, novel palladium, mild conditions, medicinal chemistry, materials science, important motif, diorganyl diselenides, catalyzed selenofluoroalkylacylation, also suitable, afford β |
| الوصف: | The trifluoromethylacyl group (−COCF 3 ) is an important motif and widely studied in catalysis, medicinal chemistry, and materials science. Herein, a novel palladium-catalyzed selenofluoroalkylacylation of terminal alkynes with commercially available fluoroalkyl anhydride and diorganyl diselenides to afford β-seleno and aryl/alkyl disubstituted enones under mild conditions is disclosed. In addition, selenodifluoroacetylations and selenoperfluoroacetylations are also suitable for this reaction. Mechanistic studies reveal that this reaction proceeds via an oxidative radical-polar crossover process. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://figshare.com/articles/journal_contribution/Selective_Access_to_Functional_Fluoroenones_via_Palladium-Catalyzed_Selenofluoroalkylacylation_of_Terminal_Alkynes/25028893Test |
| DOI: | 10.1021/acs.orglett.3c04191.s001 |
| الإتاحة: | https://doi.org/10.1021/acs.orglett.3c04191.s001Test https://figshare.com/articles/journal_contribution/Selective_Access_to_Functional_Fluoroenones_via_Palladium-Catalyzed_Selenofluoroalkylacylation_of_Terminal_Alkynes/25028893Test |
| حقوق: | CC BY-NC 4.0 |
| رقم الانضمام: | edsbas.23514E84 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/acs.orglett.3c04191.s001 |
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