المؤلفون: Finn K. Hansen, Christophe Romier, Linda Marek, Martin Marek, Manfred Jung, Christoph G. W. Gertzen, Johanna Senger, Katharina Stenzel, Viktoria Marquardt, Marc Remke, Thomas Kurz, Alexandra Hamacher, Holger Gohlke, Matthias U. Kassack

المساهمون: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (13), pp.5334-5348. ⟨10.1021/acs.jmedchem.6b01538⟩

مصطلحات موضوعية: 0301 basic medicine, Histone Deacetylases/*metabolism, Antineoplastic Agents, Apoptosis, Pharmacology, Drug Screening Assays, Cisplatin/chemistry/*pharmacology, Histone Deacetylases, Cell Line, Dose-Response Relationship, Cell Proliferation/drug effects, 03 medical and health sciences, Structure-Activity Relationship, Antineoplastic Agents/chemistry/*pharmacology, Cell Line, Tumor, Drug Discovery, medicine, Urea, Structure–activity relationship, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Histone Deacetylase Inhibitors/chemical synthesis/chemistry/*pharmacology, Cell Proliferation, Cisplatin, Tumor, Dose-Response Relationship, Drug, Molecular Structure, Cell growth, Chemistry, Apoptosis/drug effects, HDAC8, Antitumor, Squamous carcinoma, Histone Deacetylase Inhibitors, Molecular Docking Simulation, 030104 developmental biology, Cell culture, Molecular Medicine, Histone deacetylase, Drug Screening Assays, Antitumor, Drug, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae45bc45d6f85c20596af1b3e2cbe58Test
https://hal.archives-ouvertes.fr/hal-03691179Test

المؤلفون: Stephan Meister, Linda Marek, Katharina Stenzel, Benjamin Mordmüller, Matthias U. Kassack, Vicky M. Avery, Sandra Duffy, Elizabeth A. Winzeler, Finn K. Hansen, Alexandra Hamacher, Subathdrage D. M. Sumanadasa, Thomas Kurz, Rebekka Schmetter, Katherine T. Andrews, Krystina Kuna

المصدر: European Journal of Medicinal Chemistry. 82:204-213

مصطلحات موضوعية: medicine.drug_class, Plasmodium falciparum, Biology, Article, Histone Deacetylases, Antimalarials, Structure-Activity Relationship, Parasitic Sensitivity Tests, parasitic diseases, Drug Discovery, Gametocyte, medicine, Humans, Structure–activity relationship, Plasmodium berghei, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Drug discovery, Organic Chemistry, Histone deacetylase inhibitor, General Medicine, biology.organism_classification, HDAC4, Histone Deacetylase Inhibitors, Repressor Proteins, Biochemistry, Deacetylase activity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7dabd2aef875e9d10bdf649ffff8a49Test
https://doi.org/10.1016/j.ejmech.2014.05.050Test

المؤلفون: Sandra Duffy, Katherine T. Andrews, Krystina Kuna, Tina S. Skinner-Adams, Finn K. Hansen, Thomas Kurz, Subathdrage D. M. Sumanadasa, Jana Held, Vicky M. Avery, Linda Marek

المصدر: ChemMedChem. 9:665-670

مصطلحات موضوعية: Plasmodium falciparum, Biology, Pharmacology, Biochemistry, Histone H4, Antimalarials, Structure-Activity Relationship, chemistry.chemical_compound, Parasitic Sensitivity Tests, Drug Discovery, medicine, Humans, Urea, Potency, General Pharmacology, Toxicology and Pharmaceutics, Cytotoxicity, Fibroblast, IC50, Hydroxamic acid, Dose-Response Relationship, Drug, Organic Chemistry, Fibroblasts, biology.organism_classification, Histone Deacetylase Inhibitors, medicine.anatomical_structure, chemistry, Molecular Medicine, Histone deacetylase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194c6e68b474c3657c4eb64bd67ac715Test
https://doi.org/10.1002/cmdc.201300469Test

المؤلفون: Alexandra Hamacher, Holger Gohlke, Finn K. Hansen, Linda Marek, Thomas Kurz, Krystina Kuna, Matthias U. Kassack

المصدر: Journal of Medicinal Chemistry. 56:427-436

مصطلحات موضوعية: Histone deacetylase 5, Magnetic Resonance Spectroscopy, Spectrophotometry, Infrared, Chemistry, HDAC4, Molecular biology, Histone Deacetylases, Histone Deacetylase Inhibitors, Repressor Proteins, Inhibitory Concentration 50, Trichostatin A, Drug Resistance, Neoplasm, Cell culture, Cell Line, Tumor, Drug Discovery, Cancer cell, medicine, Humans, Molecular Medicine, Histone deacetylase, Linker, Vorinostat, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aca3f215406e0d50f3d61471b0cd529Test
https://doi.org/10.1021/jm301254qTest

المؤلفون: Krystina Kuna, Karin Brücher, Thomas Kurz, Lukas Spanier, Miriam Pein, Christoph T. Behrendt, Linda Marek

المصدر: European Journal of Organic Chemistry. 2009:2939-2942

مصطلحات موضوعية: Acylation, chemistry.chemical_classification, chemistry.chemical_compound, Hydroxamic acid, Hydroxylamine, chemistry, Organic Chemistry, Nitro compound, Organic chemistry, Physical and Theoretical Chemistry, Microwave assisted, Chemical synthesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0e16758afea72a9e9228d24c28227f52Test
https://doi.org/10.1002/ejoc.200900201Test

المؤلفون: Jana Held, Thomas Kurz, Vicky M. Avery, Sandra Duffy, Tina S. Skinner-Adams, Katherine T. Andrews, Krystina Kuna, Finn K. Hansen, Subathdrage D. M. Sumanadasa, Linda Marek

المصدر: ChemInform. 45

مصطلحات موضوعية: Biochemistry, Chemistry, Structure–activity relationship, General Medicine, Histone deacetylase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3eeab4f5531dba67d30b0738a33c3bbdTest
https://doi.org/10.1002/chin.201429062Test

المؤلفون: Katharine R. Trenholme, Che Julius Ngwa, David P. Fairlie, Christopher D. Goodman, Geoffrey I. McFadden, Thomas Kurz, Finn K. Hansen, Subathdrage D. M. Sumanadasa, Vicky M. Avery, Gabriele Pradel, Alice S. Butterworth, Gillian M. Fisher, Linda Marek, Katherine T. Andrews, Jonas Moecking, Sandra Duffy, Tina S. Skinner-Adams

مصطلحات موضوعية: Plasmodium, Plasmodium berghei, Plasmodium falciparum, Pharmacology, Histone Deacetylases, Small Molecule Libraries, Antimalarials, Adenosine Triphosphate, parasitic diseases, medicine, Gametocyte, Animals, Pharmacology (medical), Experimental Therapeutics, Vorinostat, biology, Lysine, Acetylation, medicine.disease, biology.organism_classification, Histone Deacetylase Inhibitors, Infectious Diseases, Trichostatin A, Histone, Biochemistry, Flagella, biology.protein, Histone deacetylase, Malaria, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6835ee244efcffbdb889eef94493ceaTest
https://europepmc.org/articles/PMC4068603Test/

المؤلفون: Linda Marek, Thomas Kurz, Karin Bruecher, Christoph T. Behrendt, Krystina Kuna, Miriam Pein, Lukas Spanier

المصدر: ChemInform. 40

مصطلحات موضوعية: Chemistry, Organic chemistry, General Medicine, Microwave assisted

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::823ffc14241fff0a4be90f22f533260cTest
https://doi.org/10.1002/chin.200942050Test

المؤلفون: Linda Marek, Stephanie Lettermann, Konstantin Agelopoulos, Thomas Kurz, Beate Lindtner, Christian Rohde, Wolfgang E. Berdel, Georg Hempel, Matthias Stelljes, Carsten Müller-Tidow

المصدر: Blood. 122:1257-1257

مصطلحات موضوعية: Immunology, Azacitidine, Myeloid leukemia, Decitabine, Cell Biology, Hematology, Biology, medicine.disease, Biochemistry, Leukemia, medicine.anatomical_structure, In vivo, medicine, Cancer research, Cytarabine, Bone marrow, Stem cell, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::628006eced65315e054e431e404b8398Test
https://doi.org/10.1182/blood.v122.21.1257.1257Test