المؤلفون: Hernandez, Sarah J, Lim, Ryan G, Onur, Tarik, Dane, Mark A, Smith, Rebecca, Wang, Keona, Jean, Grace En-Hway, Reyes-Ortiz, Andrea, Devlin, Kaylyn, Miramontes, Ricardo, Wu, Jie, Casale, Malcolm, Kilburn, David, Heiser, Laura M, Korkola, James E, Van Vactor, David, Botas, Juan, Thompson-Peer, Katherine L, Thompson, Leslie M

المصدر: Human Molecular Genetics. 32(9)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Huntington's Disease, Stem Cell Research - Induced Pluripotent Stem Cell, Stem Cell Research, Neurosciences, Brain Disorders, Neurodegenerative, Rare Diseases, Aetiology, 2.1 Biological and endogenous factors, Cardiovascular, Neurological, Humans, Integrins, Endothelial Cells, Huntington Disease, Neuroglia, Blood-Brain Barrier, Extracellular Matrix, Medical and Health Sciences, Genetics & Heredity, Genetics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/15t7q8h1Test

المؤلفون: Workman, Michael J, Lim, Ryan G, Wu, Jie, Frank, Aaron, Ornelas, Loren, Panther, Lindsay, Galvez, Erick, Perez, Daniel, Meepe, Imara, Lei, Susan, Valencia, Viviana, Gomez, Emilda, Liu, Chunyan, Moran, Ruby, Pinedo, Louis, Tsitkov, Stanislav, Ho, Ritchie, Kaye, Julia A, Consortium, the Answer ALS, Thompson, Terri, Rothstein, Jeffrey D, Finkbeiner, Steven, Fraenkel, Ernest, Sareen, Dhruv, Thompson, Leslie M, Svendsen, Clive N

المصدر: Neuron. 111(8)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Brain Disorders, Clinical Research, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Rare Diseases, Stem Cell Research - Induced Pluripotent Stem Cell, Regenerative Medicine, Genetics, Neurodegenerative, Stem Cell Research, ALS, Orphan Drug, Neurological, Humans, Amyotrophic Lateral Sclerosis, Induced Pluripotent Stem Cells, Motor Neurons, Cell Differentiation, Answer ALS Consortium, iPSC, motor neurons, sex differences, Psychology, Cognitive Sciences, Neurology & Neurosurgery, Biological psychology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8b71x7n0Test
https://escholarship.org/content/qt8b71x7n0/qt8b71x7n0.pdfTest

المؤلفون: Reyes-Ortiz, Andrea M, Abud, Edsel M, Burns, Mara S, Wu, Jie, Hernandez, Sarah J, McClure, Nicolette, Wang, Keona Q, Schulz, Corey J, Miramontes, Ricardo, Lau, Alice, Michael, Neethu, Miyoshi, Emily, Van Vactor, David, Reidling, John C, Blurton-Jones, Mathew, Swarup, Vivek, Poon, Wayne W, Lim, Ryan G, Thompson, Leslie M

المصدر: iScience. 26(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Genetics, Biological Sciences, Stem Cell Research - Induced Pluripotent Stem Cell, Neurosciences, Brain Disorders, Rare Diseases, Stem Cell Research - Nonembryonic - Human, Neurodegenerative, Huntington's Disease, Stem Cell Research, Regenerative Medicine, Underpinning research, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, Neurological, Neurology, Omics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2xj4w9rfTest

المؤلفون: Baxi, Emily G, Thompson, Terri, Li, Jonathan, Kaye, Julia A, Lim, Ryan G, Wu, Jie, Ramamoorthy, Divya, Lima, Leandro, Vaibhav, Vineet, Matlock, Andrea, Frank, Aaron, Coyne, Alyssa N, Landin, Barry, Ornelas, Loren, Mosmiller, Elizabeth, Thrower, Sara, Farr, S Michelle, Panther, Lindsey, Gomez, Emilda, Galvez, Erick, Perez, Daniel, Meepe, Imara, Lei, Susan, Mandefro, Berhan, Trost, Hannah, Pinedo, Louis, Banuelos, Maria G, Liu, Chunyan, Moran, Ruby, Garcia, Veronica, Workman, Michael, Ho, Richie, Wyman, Stacia, Roggenbuck, Jennifer, Harms, Matthew B, Stocksdale, Jennifer, Miramontes, Ricardo, Wang, Keona, Venkatraman, Vidya, Holewenski, Ronald, Sundararaman, Niveda, Pandey, Rakhi, Manalo, Danica-Mae, Donde, Aneesh, Huynh, Nhan, Adam, Miriam, Wassie, Brook T, Vertudes, Edward, Amirani, Naufa, Raja, Krishna, Thomas, Reuben, Hayes, Lindsey, Lenail, Alex, Cerezo, Aianna, Luppino, Sarah, Farrar, Alanna, Pothier, Lindsay, Prina, Carolyn, Morgan, Todd, Jamil, Arish, Heintzman, Sarah, Jockel-Balsarotti, Jennifer, Karanja, Elizabeth, Markway, Jesse, McCallum, Molly, Joslin, Ben, Alibazoglu, Deniz, Kolb, Stephen, Ajroud-Driss, Senda, Baloh, Robert, Heitzman, Daragh, Miller, Tim, Glass, Jonathan D, Patel-Murray, Natasha Leanna, Yu, Hong, Sinani, Ervin, Vigneswaran, Prasha, Sherman, Alexander V, Ahmad, Omar, Roy, Promit, Beavers, Jay C, Zeiler, Steven, Krakauer, John W, Agurto, Carla, Cecchi, Guillermo, Bellard, Mary, Raghav, Yogindra, Sachs, Karen, Ehrenberger, Tobias, Bruce, Elizabeth, Cudkowicz, Merit E, Maragakis, Nicholas, Norel, Raquel, Van Eyk, Jennifer E, Finkbeiner, Steven, Berry, James, Sareen, Dhruv, Thompson, Leslie M, Fraenkel, Ernest, Svendsen, Clive N

المصدر: Nature Neuroscience. 25(2)

مصطلحات موضوعية: Stem Cell Research, Rare Diseases, Stem Cell Research - Induced Pluripotent Stem Cell, ALS, Clinical Research, Neurodegenerative, Genetics, Neurosciences, Human Genome, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Brain Disorders, Neurological, Generic health relevance, Good Health and Well Being, Amyotrophic Lateral Sclerosis, Cell Line, Humans, Induced Pluripotent Stem Cells, Motor Neurons, Psychology, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0pm655p6Test

المؤلفون: Lim, Ryan G, Al-Dalahmah, Osama, Wu, Jie, Gold, Maxwell P, Reidling, Jack C, Tang, Guomei, Adam, Miriam, Dansu, David K, Park, Hye-Jin, Casaccia, Patrizia, Miramontes, Ricardo, Reyes-Ortiz, Andrea M, Lau, Alice, Hickman, Richard A, Khan, Fatima, Paryani, Fahad, Tang, Alice, Ofori, Kenneth, Miyoshi, Emily, Michael, Neethu, McClure, Nicolette, Flowers, Xena E, Vonsattel, Jean Paul, Davidson, Shawn, Menon, Vilas, Swarup, Vivek, Fraenkel, Ernest, Goldman, James E, Thompson, Leslie M

المصدر: Nature Communications. 13(1)

مصطلحات موضوعية: Biological Sciences, Genetics, Rare Diseases, Brain Disorders, Neurodegenerative, Neurosciences, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research, Huntington's Disease, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Humans, Mice, Biotin, Dietary Supplements, Disease Models, Animal, Huntington Disease, Mice, Transgenic, Nerve Tissue Proteins, Oligodendroglia, Solitary Nucleus, Thiamine

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5d21w80mTest

المؤلفون: Consortium, The NeuroLINCS, Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R, Simmons, Zachary, Arcila-Londono, Ximena, Lee, Edward B, Van Deerlin, Vivianna M, Shneider, Neil A, Fraenkel, Ernest, Ostrow, Lyle W, Baas, Frank, Zaitlen, Noah, Berry, James D, Malaspina, Andrea, Fratta, Pietro, Cox, Gregory A, Thompson, Leslie M, Finkbeiner, Steve, Dardiotis, Efthimios, Miller, Timothy M, Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J, Heiman-Patterson, Terry, Hammell, Molly G, Patsopoulos, Nikolaos A, Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Bowser, Robert, Harms, Matt, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J, Adams, Darius J, Stefanis, Leonidas, Gotkine, Marc, Baloh, Robert H, Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent, Broce, Iris, Drory, Vivian, Ravits, John, McMillan, Corey, Menon, Vilas, Wu, Lani, Altschuler, Steven, Li, Jonathan, Lim, Ryan G, Kaye, Julia A, Dardov, Victoria, Coyne, Alyssa N, Wu, Jie, Milani, Pamela, Cheng, Andrew, Thompson, Terri G, Ornelas, Loren, Frank, Aaron, Adam, Miriam, Banuelos, Maria G, Casale, Malcolm, Cox, Veerle, Escalante-Chong, Renan, Daigle, J Gavin, Gomez, Emilda, Hayes, Lindsey, Holewenski, Ronald, Lei, Susan, Lenail, Alex, Lima, Leandro, Mandefro, Berhan, Matlock, Andrea, Panther, Lindsay, Patel-Murray, Natasha Leanna, Pham, Jacqueline, Ramamoorthy, Divya, Sachs, Karen, Shelley, Brandon, Stocksdale, Jennifer, Trost, Hannah, Wilhelm, Mark, Venkatraman, Vidya, Wassie, Brook T, Wyman, Stacia, Yang, Stephanie, Consortium, NYGC ALS, Van Eyk, Jennifer E, Lloyd, Thomas E, Finkbeiner, Steven

المصدر: iScience. 24(11)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Neurodegenerative, Clinical Research, ALS, Stem Cell Research, Rare Diseases, Acquired Cognitive Impairment, Stem Cell Research - Induced Pluripotent Stem Cell, Brain Disorders, Neurosciences, Dementia, Stem Cell Research - Induced Pluripotent Stem Cell - Human, 2.1 Biological and endogenous factors, Aetiology, Neurological, Good Health and Well Being, NeuroLINCS Consortium, NYGC ALS Consortium, Biological sciences, Neuroscience, Omics, Systems biology, Systems neuroscience

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7380047kTest

المؤلفون: Morozko, Eva L, Smith-Geater, Charlene, Monteys, Alejandro Mas, Pradhan, Subrata, Lim, Ryan G, Langfelder, Peter, Kachemov, Marketta, Kulkarni, Jayesh A, Zaifman, Josh, Hill, Austin, Stocksdale, Jennifer T, Cullis, Pieter R, Wu, Jie, Ochaba, Joseph, Miramontes, Ricardo, Chakraborty, Anirban, Hazra, Tapas K, Lau, Alice, St-cyrc, Sophie, Orellana, Iliana, Kopan, Lexi, Wang, Keona Q, Yeung, Sylvia, Leavitt, Blair R, Reidling, Jack C, Yang, X William, Steffan, Joan S, Davidson, Beverly L, Sarkar, Partha S, Thompson, Leslie M

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(32)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Clinical Sciences, Genetics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3qr022tsTest

المؤلفون: Sanchez, Isabella I, Nguyen, Thai B, England, Whitney E, Lim, Ryan G, Vu, Anthony Q, Miramontes, Ricardo, Byrne, Lauren M, Markmiller, Sebastian, Lau, Alice L, Orellana, Iliana, Curtis, Maurice A, Faull, Richard Lewis Maxwell, Yeo, Gene W, Fowler, Christie D, Reidling, Jack C, Wild, Edward J, Spitale, Robert C, Thompson, Leslie M

المصدر: Journal of Clinical Investigation. 131(12)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Rare Diseases, Genetics, Brain Disorders, Neurodegenerative, Huntington's Disease, Neurosciences, Aetiology, 2.1 Biological and endogenous factors, Neurological, Animals, Cytoplasmic Granules, DNA Helicases, DNA-Binding Proteins, Female, Hippocampus, Humans, Huntington Disease, Male, Mice, MicroRNAs, Neurons, Poly-ADP-Ribose Binding Proteins, Prefrontal Cortex, Protein Transport, RNA Helicases, RNA Recognition Motif Proteins, Neurodegeneration, Neuroscience, Medical and Health Sciences, Immunology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0g99m33jTest

المؤلفون: Morozko, Eva L, Smith-Geater, Charlene, Monteys, Alejandro Mas, Pradhan, Subrata, Lim, Ryan G, Langfelder, Peter, Kachemov, Marketta, Kulkarni, Jayesh A, Zaifman, Josh, Hill, Austin, Stocksdale, Jennifer T, Cullis, Pieter R, Wu, Jie, Ochaba, Joseph, Miramontes, Ricardo, Chakraborty, Anirban, Hazra, Tapas K, Lau, Alice, St-cyr, Sophie, Orellana, Iliana, Kopan, Lexi, Wang, Keona Q, Yeung, Sylvia, Leavitt, Blair R, Reidling, Jack C, Yang, X William, Steffan, Joan S, Davidson, Beverly L, Sarkar, Partha S, Thompson, Leslie M

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Genetics, Biological Sciences, Neurosciences, Huntington's Disease, Brain Disorders, Neurodegenerative, Stem Cell Research, Rare Diseases, Underpinning research, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Cell Differentiation, DNA, DNA Damage, DNA Repair, DNA Repair Enzymes, Disease Models, Animal, Female, Humans, Huntingtin Protein, Huntington Disease, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Neurons, Phosphotransferases (Alcohol Group Acceptor), Pluripotent Stem Cells, Primary Cell Culture, Protein Inhibitors of Activated STAT, Protein Processing, Post-Translational, RNA, Small Interfering, Small Ubiquitin-Related Modifier Proteins, Sumoylation, Transcription, Genetic, DNA damage repair, SUMO, PIAS, Huntington's disease, PNKP

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6np4540mTest

المؤلفون: Kedaigle, Amanda J, Fraenkel, Ernest, Atwal, Ranjit S, Wu, Min, Gusella, James F, MacDonald, Marcy E, Kaye, Julia A, Finkbeiner, Steven, Mattis, Virginia B, Tom, Colton M, Svendsen, Clive, King, Alvin R, Chen, Yumay, Stocksdale, Jennifer T, Lim, Ryan G, Casale, Malcolm, Wang, Ping H, Thompson, Leslie M, Akimov, Sergey S, Ratovitski, Tamara, Arbez, Nicolas, Ross, Christopher A

المصدر: Human Molecular Genetics. 29(11)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Neurosciences, Huntington's Disease, Stem Cell Research, Brain Disorders, Regenerative Medicine, Neurodegenerative, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, Neurological, Adenosine Triphosphate, Cell Differentiation, Cell Line, Corpus Striatum, Energy Metabolism, Glycolysis, Humans, Huntington Disease, Induced Pluripotent Stem Cells, Metabolome, Mitochondria, Neurons, Oxidative Phosphorylation, HD iPSC Consortium, Medical and Health Sciences, Genetics & Heredity, Genetics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9h03m40rTest