المؤلفون: Rodriguez-Zabala, Maria, Ramakrishnan, Ramprasad, Reinbach, Katrin, Ghosh, Somadri, Oburoglu, Leal, Falqués-Costa, Antoni, Bellamkonda, Kishan, Ehinger, Mats, Peña-Martínez, Pablo, Puente-Moncada, Noelia, Lilljebjörn, Henrik, Cammenga, Jörg, Pronk, Cornelis Jan, Lazarevic, Vladimir, Fioretos, Thoas, Hagström-Andersson, Anna K., Woods, Niels Bjarne, Järås, Marcus

المصدر: Blood Advances StemTherapy: National Initiative on Stem Cells for Regenerative Therapy. 7(18):5382-5395

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Hematologi, Medical and Health Sciences, Clinical Medicine, Hematology, Medicinska och farmaceutiska grundvetenskaper, Cell- och molekylärbiologi, Basic Medicine, Cell and Molecular Biology

الوصول الحر: https://lup.lub.lu.se/record/538bc163-463c-483d-acbd-781714e40337Test
http://dx.doi.org/10.1182/bloodadvances.2023009967Test

المؤلفون: Ågerstam, Helena, Lilljebjörn, Henrik, Rissler, Marianne, Sandén, Carl, Fioretos, Thoas

المصدر: Haematologica. 108(2):599-604

مصطلحات موضوعية: Child, Humans, Core Binding Factor Alpha 2 Subunit/genetics, Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Oncogene Proteins, Fusion/genetics, Interleukin-1 Receptor Accessory Protein, Medicin och hälsovetenskap, Klinisk medicin, Hematologi, Medical and Health Sciences, Clinical Medicine, Hematology, Cancer och onkologi, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/aa045baf-5a68-45bf-ac27-e9f0e8257618Test
http://dx.doi.org/10.3324/haematol.2022.281059Test

المؤلفون: Ragnarsson, Charlotte, Yang, Minjun, Moura-Castro, Larissa Helena, Aydın, Efe, Gunnarsson, Rebeqa, Olsson-Arvidsson, Linda, Lilljebjörn, Henrik, Fioretos, Thoas, Duployez, Nicolas, Zaliova, Marketa, Zuna, Jan, Castor, Anders, Johansson, Bertil, Paulsson, Kajsa

المصدر: Genes Chromosomes and Cancer. 63(5)

مصطلحات موضوعية: ARID5B variants, B-cell precursor acute lymphoblastic leukemia, constitutional, high hyperdiploidy, pediatric, somatic, Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/fd1aac37-db36-4d76-97b2-87b0e31f23e6Test
http://dx.doi.org/10.1002/gcc.23242Test

المؤلفون: Johansson, Therese B., Davtyan, Rubina, Valderas-Gutiérrez, Julia, Gonzalez Rodriguez, Adrian, 1988, Agnarsson, Björn, 1977, Munita, Roberto, Fioretos, Thoas, Lilljebjörn, Henrik, Linke, Heiner, Höök, Fredrik, 1966, Prinz, Christelle N.

المصدر: Enmolekyldetektion för precisionsdiagnostik av cancer Nanomaterials. 14(5)

مصطلحات موضوعية: nanowires, oligonucleotides, molecular beacons, limit of detection, lightguiding

وصف الملف: electronic

الوصول الحر: https://research.chalmers.se/publication/540596Test
https://research.chalmers.se/publication/540596/file/540596_Fulltext.pdfTest

المؤلفون: Abolhalaj, Milad, Sincic, Viktor, Lilljebjörn, Henrik, Sandén, Carl, Aab, Alar, Hägerbrand, Karin, Ellmark, Peter, Borrebaeck, Carl, Fioretos, Thoas, Lundberg, Kristina

المصدر: Cancer Medicine. 11(15):3023-3032

مصطلحات موضوعية: T-cell, RNA-Sequencing, acute myeloid leukemia (AML), TP53, Immunotherapy, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Immunologi inom det medicinska området, Medical and Health Sciences, Basic Medicine, Immunology in the medical area, Klinisk medicin, Cancer och onkologi, Clinical Medicine, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/f6e78fbd-d5e5-4afd-b4cc-db90f8a78aa8Test
http://dx.doi.org/10.1002/cam4.4661Test

المؤلفون: Krali, Olga, Marincevic-Zuniga, Yanara, Arvidsson, Gustav, Enblad, Anna Pia, Lundmark, Anders, Sayyab, Shumaila, Zachariadis, Vasilios, Heinäniemi, Merja, Suhonen, Janne, Oksa, Laura, Vepsäläinen, Kaisa, Öfverholm, Ingegerd, Barbany, Gisela, Nordgren, Ann, Lilljebjörn, Henrik, Fioretos, Thoas, Madsen, Hans O., Marquart, Hanne Vibeke, Flaegstad, Trond, Forestier, Erik, Jónsson, Ólafur G., Kanerva, Jukka, Lohi, Olli, Norén-Nyström, Ulrika, Schmiegelow, Kjeld, Harila, Arja, Heyman, Mats, Lönnerholm, Gudmar, Syvänen, Ann Christine, Nordlund, Jessica

المساهمون: HUS Children and Adolescents, Children's Hospital

مصطلحات موضوعية: 3123 Gynaecology and paediatrics

وصف الملف: application/pdf

العلاقة: This work was supported by grants from the Swedish Research Council (2019-01976 to JN), the Swedish Cancer Society (CAN2018-623 to ACS and CAN2022-2395 to JN), the Swedish Childhood Cancer Foundation (PR2017-0023 to ACS and PR2019-0046 to JN), the Göran Gustafsons Foundation (to JN), the Jane and Aatos Erkko Foundation and the Academy of Finland #321550 (to OL and MH). DNA methylation array analysis and RNA-sequencing was performed with assistance from the SciLifeLab National Genomics Infrastructure, SNP&SEQ Technology Platform, which is funded by the Swedish Research Council and the Knut and Alice Wallenberg Foundation. Computational resources were provided by the Swedish National Infrastructure for Computing (SNIC), National Academic Infrastructure for Supercomputing in Sweden (NAISS) and the Finnish IT Centre of Science (CSC) and University of Eastern Finland Bioinformatics Center. SNIC and NAISS are partially funded by the Swedish Research Council. We thank Sara Nystedt and Sara Nilsson for technical assistance, Jonas Carlsson Almlöf and Christofer Bäcklin for input on DNA methylation classification, and our colleagues from NOPHO LL Biology Group, Lucia Cavelier, Anna Bremer and Tatjana Pandzic for valuable input on the study design. We especially thank the ALL patients who contributed samples to this study. Figures 1 , 5f and Supplementary Figs. 2 –3 were made with Biorender.com. This work was supported by grants from the Swedish Research Council (2019-01976 to JN), the Swedish Cancer Society (CAN2018-623 to ACS and CAN2022-2395 to JN), the Swedish Childhood Cancer Foundation (PR2017-0023 to ACS and PR2019-0046 to JN), the Göran Gustafsons Foundation (to JN), the Jane and Aatos Erkko Foundation and the Academy of Finland #321550 (to OL and MH). DNA methylation array analysis and RNA-sequencing was performed with assistance from the SciLifeLab National Genomics Infrastructure, SNP&SEQ Technology Platform, which is funded by the Swedish Research Council and the Knut and Alice Wallenberg Foundation. Computational resources were provided by the Swedish National Infrastructure for Computing (SNIC), National Academic Infrastructure for Supercomputing in Sweden (NAISS) and the Finnish IT Centre of Science (CSC) and University of Eastern Finland Bioinformatics Center. SNIC and NAISS are partially funded by the Swedish Research Council. We thank Sara Nystedt and Sara Nilsson for technical assistance, Jonas Carlsson Almlöf and Christofer Bäcklin for input on DNA methylation classification, and our colleagues from NOPHO LL Biology Group, Lucia Cavelier, Anna Bremer and Tatjana Pandzic for valuable input on the study design. We especially thank the ALL patients who contributed samples to this study. Figures , and Supplementary Figs. – were made with Biorender.com.; Krali , O , Marincevic-Zuniga , Y , Arvidsson , G , Enblad , A P , Lundmark , A , Sayyab , S , Zachariadis , V , Heinäniemi , M , Suhonen , J , Oksa , L , Vepsäläinen , K , Öfverholm , I , Barbany , G , Nordgren , A , Lilljebjörn , H , Fioretos , T , Madsen , H O , Marquart , H V , Flaegstad , T , Forestier , E , Jónsson , Ó G , Kanerva , J , Lohi , O , Norén-Nyström , U , Schmiegelow , K , Harila , A , Heyman , M , Lönnerholm , G , Syvänen , A C & Nordlund , J 2023 , ' Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia ' , npj precision oncology , vol. 7 , no. 1 , 131 . https://doi.org/10.1038/s41698-023-00479-5Test; 85179355296; aa32a370-320f-4208-a5ce-18911fd6fe8f; http://hdl.handle.net/10138/569290Test; 001118015800003

الإتاحة: http://hdl.handle.net/10138/569290Test

المؤلفون: Modvig, Signe, Wernersson, Rasmus, Øbro, Nina Friesgaard, Olsen, Lars Rønn, Christensen, Claus, Rosthøj, Susanne, Degn, Matilda, Jürgensen, Gitte Wullf, Madsen, Hans O., Albertsen, Birgitte Klug, Wehner, Peder Skov, Rosthøj, Steen, Lilljebjörn, Henrik, Fioretos, Thoas, Schmiegelow, Kjeld, Marquart, Hanne Vibeke

المصدر: Molecular Oncology. 16(10):2015-2030

مصطلحات موضوعية: acute lymphoblastic leukemia, CD34, cell migration, immunophenotype, prognosis, protein–protein interaction networks, Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/80a85686-3451-40f8-97dd-34d336f4c90cTest
http://dx.doi.org/10.1002/1878-0261.13207Test

المؤلفون: Lilljebjörn, Henrik, Orsmark-Pietras, Christina, Mitelman, Felix, Hagström-Andersson, Anna, Fioretos, Thoas

المصدر: Seminars in Cancer Biology. 84:40-49

مصطلحات موضوعية: Acute lymphoblastic leukemia, Acute myeloid leukemia, Classification, Diagnostics, Gene fusions, Precision medicine, RNA-sequencing, Whole transcriptome sequencing, Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/c25f5563-276f-41b0-a890-fe0cdf44ff83Test
http://dx.doi.org/10.1016/j.semcancer.2021.09.013Test

المؤلفون: Orsmark-Pietras, Christina, Landberg, Niklas, Lorenz, Fryderyk, Uggla, Bertil, Höglund, Martin, Lehmann, Sören, Derolf, Åsa, Deneberg, Stefan, Antunovic, Petar, Cammenga, Jörg, Möllgård, Lars, Wennström, Lovisa, Lilljebjörn, Henrik, Rissler, Marianne, Fioretos, Thoas, Lazarevic, Vladimir Lj

المصدر: Genes, Chromosomes and Cancer. 60(6):426-433

مصطلحات موضوعية: Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Medicinsk genetik, Medical and Health Sciences, Basic Medicine, Medical Genetics, Klinisk medicin, Hematologi, Clinical Medicine, Hematology, Cancer och onkologi, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/ce92906e-28cc-4057-a266-6079bf68b38bTest
http://dx.doi.org/10.1002/gcc.22936Test

المؤلفون: Krali, Olga, Marincevic-Zuniga, Yanara, Arvidsson, Gustav, Enblad, Anna Pia, Lundmark, Anders, Sayyab, Shumaila, Zachariadis, Vasilios, Heinäniemi, Merja, Suhonen, Janne, Oksa, Laura, Vepsäläinen, Kaisa, Öfverholm, Ingegerd, Barbany, Gisela, Nordgren, Ann, Lilljebjörn, Henrik, Fioretos, Thoas, Madsen, Hans O., Marquart, Hanne Vibeke, Flaegstad, Trond, Forestier, Erik, Jónsson, Ólafur G., Kanerva, Jukka, Lohi, Olli, Norén-Nyström, Ulrika, Schmiegelow, Kjeld, Harila, Arja, Heyman, Mats, Lönnerholm, Gudmar, Syvänen, Ann Christine, Nordlund, Jessica

المصدر: NPJ precision oncology. 7(1)

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/98c6efff-535e-43fc-a5a7-dfd3e89816d8Test
http://dx.doi.org/10.1038/s41698-023-00479-5Test