دورية أكاديمية
Misdiagnosis of Clostridioides difficile Infections by Standard-of-Care Specimen Collection and Testing among Hospitalized Adults, Louisville, Kentucky, USA, 2019–2020
| العنوان: | Misdiagnosis of Clostridioides difficile Infections by Standard-of-Care Specimen Collection and Testing among Hospitalized Adults, Louisville, Kentucky, USA, 2019–2020 |
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| المؤلفون: | Julio A. Ramirez, Frederick J. Angulo, Ruth M. Carrico, Stephen Furmanek, Senén Peña Oliva, Joann M. Zamparo, Elisa Gonzalez, Pingping Zhang, Leslie A. Wolf Parrish, Subathra Marimuthu, Michael W. Pride, Sharon Gray, Cátia S. Matos Ferreira, Forest W. Arnold, Raul E. Istúriz, Nadia Minarovic, Jennifer C. Moïsi, Luis Jodar |
| المصدر: | Emerging Infectious Diseases, Vol 29, Iss 5, Pp 919-928 (2023) |
| بيانات النشر: | Centers for Disease Control and Prevention, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Clostridioides difficile, misdiagnosis, bacteria, infections, clinical laboratory techniques, standard-of-care specimen collection, Medicine, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Although Clostridioides difficile infection (CDI) incidence is high in the United States, standard-of-care (SOC) stool collection and testing practices might result in incidence overestimation or underestimation. We conducted diarrhea surveillance among inpatients >50 years of age in Louisville, Kentucky, USA, during October 14, 2019–October 13, 2020; concurrent SOC stool collection and CDI testing occurred independently. A study CDI case was nucleic acid amplification test‒/cytotoxicity neutralization assay‒positive or nucleic acid amplification test‒positive stool in a patient with pseudomembranous colitis. Study incidence was adjusted for hospitalization share and specimen collection rate and, in a sensitivity analysis, for diarrhea cases without study testing. SOC hospitalized CDI incidence was 121/100,000 population/year; study incidence was 154/100,000 population/year and, in sensitivity analysis, 202/100,000 population/year. Of 75 SOC CDI cases, 12 (16.0%) were not study diagnosed; of 109 study CDI cases, 44 (40.4%) were not SOC diagnosed. CDI incidence estimates based on SOC CDI testing are probably underestimated. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1080-6040 1080-6059 |
| العلاقة: | https://wwwnc.cdc.gov/eid/article/29/5/22-1618_articleTest; https://doaj.org/toc/1080-6040Test; https://doaj.org/toc/1080-6059Test |
| DOI: | 10.3201/eid2905.221618 |
| الوصول الحر: | https://doaj.org/article/3ace3b17f58345e78c03bef3512d31eeTest |
| رقم الانضمام: | edsdoj.3ace3b17f58345e78c03bef3512d31ee |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10806040 10806059 |
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| DOI: | 10.3201/eid2905.221618 |