المؤلفون: Sørensen, Christoffer V., Fernández, Julián, Christina Adams, Anna, Wildenauer, Helen H. K., Schoffelen, Sanne, Ledsgaard, Line, Pucca, Manuela B., Fiebig, Michael, Cerni, Felipe A., Tulika, Tulika, Voldborg, Bjørn G., Karatt-Vellat, Aneesh, Morth, J. Preben, Ljungars, Anne, Grav, Lise M., Lomonte, Bruno, Laustsen, Andreas H.

المصدر: Sørensen , C V , Fernández , J , Christina Adams , A , Wildenauer , H H K , Schoffelen , S , Ledsgaard , L , Pucca , M B , Fiebig , M , Cerni , F A , Tulika , T , Voldborg , B G , Karatt-Vellat , A , Morth , J P , Ljungars , A , Grav , L M , Lomonte , B & Laustsen , A H 2024 , ' Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper ' , Nature Communications , vol. 15 , 173 ....

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/77c853e2-1544-4350-a460-3f01a196f7b9Test

الإتاحة: https://doi.org/10.1038/s41467-023-42624-5Test
https://orbit.dtu.dk/en/publications/77c853e2-1544-4350-a460-3f01a196f7b9Test
https://backend.orbit.dtu.dk/ws/files/349794662/s41467-023-42624-5.pdfTest

المؤلفون: Patel, Rohit N., Clare, Rachel H., Ledsgaard, Line, Nys, Mieke, Kool, Jeroen, Laustsen, Andreas H., Ulens, Chris, Casewell, Nicholas R.

المصدر: Patel , R N , Clare , R H , Ledsgaard , L , Nys , M , Kool , J , Laustsen , A H , Ulens , C & Casewell , N R 2023 , ' An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules ' , Biochemical Pharmacology , vol. 216 , 115758 , pp. 1-13 . https://doi.org/10.1016/j.bcp.2023.115758Test

مصطلحات موضوعية: Antibody discovery, Antivenom, Drug discovery, nicotinic acetylcholine receptor (nAChR), Snake venom neurotoxin, Three-finger toxin, α-neurotoxins

العلاقة: https://research.vu.nl/en/publications/40fd6f22-a650-4d97-8862-52cf84797ac4Test

الإتاحة: https://doi.org/10.1016/j.bcp.2023.115758Test
https://research.vu.nl/en/publications/40fd6f22-a650-4d97-8862-52cf84797ac4Test
https://hdl.handle.net/1871.1/40fd6f22-a650-4d97-8862-52cf84797ac4Test
http://www.scopus.com/inward/record.url?scp=85169881174&partnerID=8YFLogxKTest
http://www.scopus.com/inward/citedby.url?scp=85169881174&partnerID=8YFLogxKTest

المؤلفون: Ledsgaard, Line, Wade, Jack, Jenkins, Timothy P., Boddum, Kim, Oganesyan, Irina, id_orcid:0 000-0002-4250-1992, Harrison, Julian A., Villar, Pedro, Leah, Rachael A., Zenobi, Renato, id_orcid:0 000-0001-5211-4358, Schoffelen, Sanne, Voldborg, Bjørn, Ljungars, Anne, McCafferty, John, Lomonte, Bruno, Gutiérrez, José M., Laustsen, Andreas H., Karatt-Vellatt, Aneesh

المصدر: Nature Communications, 14 (1)

وصف الملف: application/application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/wos/001003115900018; info:eu-repo/grantAgreement/SNF/Projekte MINT/178765; info:eu-repo/grantAgreement/SNF/Projekte MINT/207354; info:eu-repo/grantAgreement/SNF/R'Equip/198122; http://hdl.handle.net/20.500.11850/598916Test

الإتاحة: https://doi.org/20.500.11850/598916Test
https://doi.org/10.3929/ethz-b-000598916Test
https://doi.org/10.1038/s41467-023-36393-4Test
https://hdl.handle.net/20.500.11850/598916Test

المؤلفون: Sørensen, Christoffer V., Ledsgaard, Line, Wildenauer, Helen H. K., Dahl, Camilla H., Ebersole, Tasja W., Bohn, Markus-Frederik, Ljungars, Anne, Jenkins, Timothy P., Laustsen, Andreas H.

المصدر: Sørensen , C V , Ledsgaard , L , Wildenauer , H H K , Dahl , C H , Ebersole , T W , Bohn , M-F , Ljungars , A , Jenkins , T P & Laustsen , A H 2023 , ' Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy ' , Scientific Reports , vol. 13 , 10181 . https://doi.org/10.1038/s41598-023-37056-6Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/6f3f09fb-2aa1-40fc-bfa2-dd409bcfab92Test

الإتاحة: https://doi.org/10.1038/s41598-023-37056-6Test
https://orbit.dtu.dk/en/publications/6f3f09fb-2aa1-40fc-bfa2-dd409bcfab92Test
https://backend.orbit.dtu.dk/ws/files/327209815/s41598_023_37056_6.pdfTest

المؤلفون: Tulika, Tulika, Pedersen, Rasmus W., Rimbault, Charlotte, Ahmadi, Shirin, Rivera-de-Torre, Esperanza, Fernández-Quintero, Monica L., Loeffler, Johannes R., Bohn, Markus-Frederik, Ljungars, Anne, Ledsgaard, Line, Voldborg, Bjørn G., Ruso-Julve, Fulgencio, Andersen, Jan Terje, Laustsen, Andreas H.

المصدر: Tulika , T , Pedersen , R W , Rimbault , C , Ahmadi , S , Rivera-de-Torre , E , Fernández-Quintero , M L , Loeffler , J R , Bohn , M-F , Ljungars , A , Ledsgaard , L , Voldborg , B G , Ruso-Julve , F , Andersen , J T & Laustsen , A H 2023 , ' Phage display assisted discovery of a pH-dependent anti-α-cobratoxin antibody from a natural variable domain library ' , Protein Science , vol. 32 , no. 12 , e4821 . https://doi.org/10.1002/pro.4821Test

مصطلحات موضوعية: Acid-switched antibodies, Antibody developability, Antibody recycling, Chain-shuffling, pH-dependent antibodies, Phage display technology, Snake venom, Snake toxins

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/9fb13442-516d-44f6-b404-15a18f19b52cTest

الإتاحة: https://doi.org/10.1002/pro.4821Test
https://orbit.dtu.dk/en/publications/9fb13442-516d-44f6-b404-15a18f19b52cTest
https://backend.orbit.dtu.dk/ws/files/341486913/Protein_Science_-_2023_-_Tulika_-_Phage_display_assisted_discovery_of_a_pH_dependent_anti_cobratoxin_antibody_from_a.pdfTest

المؤلفون: Fiil, Berthe Katrine, Thrane, Sandra Wingaard, Pichler, Michael, Kittilä, Tiia, Ledsgaard, Line, Ahmadi, Shirin, Hermansen, Grith Miriam Maigaard, Jelsbak, Lars, Lauridsen, Charlotte, Brix, Susanne, Laustsen, Andreas Hougaard

المصدر: Fiil , B K , Thrane , S W , Pichler , M , Kittilä , T , Ledsgaard , L , Ahmadi , S , Hermansen , G M M , Jelsbak , L , Lauridsen , C , Brix , S & Laustsen , A H 2022 , ' Orally active bivalent V H H construct prevents proliferation of F4 + enterotoxigenic Escherichia coli in weaned piglets ' , iScience , vol. 25 , no. 4 , 104003 . https://doi.org/10.1016/j.isci.2022.104003Test

مصطلحات موضوعية: Infection control in health technology, Microbiology, Porcine medicine

الإتاحة: https://doi.org/10.1016/j.isci.2022.104003Test
https://pure.au.dk/portal/da/publications/orally-active-bivalent-vhh-construct-prevents-proliferation-of-f4-enterotoxigenic-escherichia-coli-in-weaned-pigletsTest(fe97e58b-0b63-471c-9939-461ad6e40244).html
http://www.scopus.com/inward/record.url?scp=85127578491&partnerID=8YFLogxKTest

المؤلفون: Wade, Jack, Rimbault, Charlotte, Ali, Hanif, Ledsgaard, Line, Rivera-de-Torre, Esperanza, Abou Hachem, Maher, Boddum, Kim, Mirza, Nadia, Bohn, Markus-Frederik, Sakya, Siri A, Ruso-Julve, Fulgencio, Andersen, Jan Terje, Laustsen, Andreas H.

المصدر: Wade , J , Rimbault , C , Ali , H , Ledsgaard , L , Rivera-de-Torre , E , Abou Hachem , M , Boddum , K , Mirza , N , Bohn , M-F , Sakya , S A , Ruso-Julve , F , Andersen , J T & Laustsen , A H 2022 , ' Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes ' , Bioconjugate Chemistry , vol. 33 , no. 8 , pp. 1494-1504 . https://doi.org/10.1021/acs.bioconjchem.2c00220Test

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/0fd2e0ad-9dd9-4e55-b5ea-ccd7c8ff706bTest

الإتاحة: https://doi.org/10.1021/acs.bioconjchem.2c00220Test
https://orbit.dtu.dk/en/publications/0fd2e0ad-9dd9-4e55-b5ea-ccd7c8ff706bTest
https://backend.orbit.dtu.dk/ws/files/282767578/acs.bioconjchem.2c00220.pdfTest

المؤلفون: Ledsgaard, Line, Laustsen, Andreas H., Pus, Urska, Wade, Jack, Villar, Pedro, Boddum, Kim, Slavny, Peter, Masters, Edward W., Arias, Ana S., Oscoz, Saioa, Griffiths, Daniel T., Luther, Alice M., Lindholm, Majken, Leah, Rachael A., Møller, Marie Sofie, Ali, Hanif, McCafferty, John, Lomonte, Bruno, Gutiérrez, José M., Karatt-Vellatt, Aneesh

المصدر: Ledsgaard , L , Laustsen , A H , Pus , U , Wade , J , Villar , P , Boddum , K , Slavny , P , Masters , E W , Arias , A S , Oscoz , S , Griffiths , D T , Luther , A M , Lindholm , M , Leah , R A , Møller , M S , Ali , H , McCafferty , J , Lomonte , B , Gutiérrez , J M & Karatt-Vellatt , A 2022 , ' In vitro discovery of a human monoclonal antibody that ....

مصطلحات موضوعية: Recombiant antivenom, Antibody discovery, Affinity maturation, Venom neutralization, Snake neurotoxins, Monoclonal antibodies, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/8ed85b72-63ee-4756-a371-c0a2b8b2f628Test

الإتاحة: https://doi.org/10.1080/19420862.2022.2085536Test
https://orbit.dtu.dk/en/publications/8ed85b72-63ee-4756-a371-c0a2b8b2f628Test
https://backend.orbit.dtu.dk/ws/files/278574119/In_vitro_discovery_of_a_human_monoclonal_antibody_that_neutralizes_lethality_of_cobra_snake_venom.pdfTest

المؤلفون: Ledsgaard, Line, Ljungars, Anne, Rimbault, Charlotte, Sørensen, Christoffer V., Tulika, Tulika, Wade, Jack, Wouters, Yessica, McCafferty, John, Laustsen, Andreas H.

المصدر: Ledsgaard , L , Ljungars , A , Rimbault , C , Sørensen , C V , Tulika , T , Wade , J , Wouters , Y , McCafferty , J & Laustsen , A H 2022 , ' Advances in antibody phage display technology ' , Drug Discovery Today , vol. 27 , no. 8 , pp. 2151-2169 . https://doi.org/10.1016/j.drudis.2022.05.002Test

مصطلحات موضوعية: Phage display, Antibody discovery, Antigen presentation, Selection strategy, Library design

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/150c5896-d4d7-4692-834e-c5e3a315b7fbTest

الإتاحة: https://doi.org/10.1016/j.drudis.2022.05.002Test
https://orbit.dtu.dk/en/publications/150c5896-d4d7-4692-834e-c5e3a315b7fbTest
https://backend.orbit.dtu.dk/ws/files/278575565/1_s2.0_S1359644622001738_main.pdfTest

المؤلفون: Bullen, Georgia, Galson, Jacob D., Hall, Gareth, Villar, Pedro, Moreels, Lien, Ledsgaard, Line, Mattiuzzo, Giada, Bentley, Emma M., Masters, Edward W., Tang, David, Millett, Sophie, Tongue, Danielle, Brown, Richard, Diamantopoulos, Ioannis, Parthiban, Kothai, Tebbutt, Claire, Leah, Rachael, Chaitanya, Krishna, Ergueta-Carballo, Sandra, Pazeraitis, Deividas, Surade, Sachin B., Ashiru, Omodele, Crippa, Lucia, Cowan, Richard, Bowler, Matthew W., Campbell, Jamie I., Lee, Wing-Yiu Jason, Carr, Mark D., Matthews, David, Pfeffer, Paul, Hufton, Simon E., Sawmynaden, Kovilen, Osbourn, Jane, McCafferty, John, Karatt-Vellatt, Aneesh

المصدر: Frontiers in Immunology ; volume 12 ; ISSN 1664-3224

الإتاحة: https://doi.org/10.3389/fimmu.2021.678570Test