المؤلفون: Duivelshof, Bastiaan, Bouvarel, Thomas, Pirner, Sebastian, Larraillet, Vincent, Knaupp, Alexander, Koll, Hans, D'Atri, Valentina, Guillarme, Davy

المصدر: ISSN: 1422-0067 ; International journal of molecular sciences, vol. 24, no. 23 (2023) p. 16623.

مصطلحات موضوعية: info:eu-repo/classification/ddc/615, Fab fragment, Bispecific antibody, Ion exchange chromatography, Monoclonal antibody, Organic modifier, Salt gradient, Salt-mediated pH gradient

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38068945; https://archive-ouverte.unige.ch/unige:174031Test; unige:174031

الإتاحة: https://doi.org/10.3390/ijms242316623Test
https://archive-ouverte.unige.ch/unige:174031Test

المؤلفون: Kufer, Regina¹ (AUTHOR) regina.kufer@roche.com, Larraillet, Vincent² (AUTHOR), Thalhauser, Sabrina¹ (AUTHOR), Graf, Tobias¹ (AUTHOR), Endesfelder, Manuel² (AUTHOR), Wohlrab, Stefanie¹ (AUTHOR)

المصدر: Journal of Pharmaceutical Sciences. Jun2024, Vol. 113 Issue 6, p1470-1477. 8p.

مصطلحات موضوعية: *LIQUID chromatography-mass spectrometry, *UBIQUITIN, *MONOCLONAL antibodies, *POST-translational modification, *DRUG stability

المؤلفون: Murisier, Amarande, D'Atri, Valentina, Pirner, Sebastian, Larraillet, Vincent, Fekete, Szabolcs, Lauber, Matthew, Guillarme, Davy

المصدر: ISSN: 1999-4923 ; Pharmaceutics, vol. 14, no. 11 (2022) 2315.

مصطلحات موضوعية: info:eu-repo/classification/ddc/615, Bispecific antibodies, Improved selectivity, Method robustness, Reversed-phase liquid chromatography, Ultra-short columns

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36365134; https://archive-ouverte.unige.ch/unige:165228Test; unige:165228

الإتاحة: https://doi.org/10.3390/pharmaceutics14112315Test
https://archive-ouverte.unige.ch/unige:165228Test

المؤلفون: Murisier, Amarande, D'Atri, Valentina, Larraillet, Vincent, Pirner, Sebastian, Guillarme, Davy

المصدر: ISSN: 2297-8739 ; Separations, vol. 9, no. 9 (2022) 243.

مصطلحات موضوعية: info:eu-repo/classification/ddc/615

العلاقة: https://archive-ouverte.unige.ch/unige:164436Test; unige:164436

الإتاحة: https://doi.org/10.3390/separations9090243Test
https://archive-ouverte.unige.ch/unige:164436Test

المؤلفون: Duivelshof, Bastiaan Laurens, Bouvarel, Thomas, Pirner, Sebastian, Larraillet, Vincent, Knaupp, Alexander, Koll, Hans, D'Atri, Valentina, Guillarme, Davy

المصدر: International Journal of Molecular Sciences; Dec2023, Vol. 24 Issue 23, p16623, 15p

مصطلحات موضوعية: ION exchange chromatography, MONOCLONAL antibodies, BISPECIFIC antibodies, BIOPHARMACEUTICS, POST-translational modification, PROTEINS

المؤلفون: Kufer, Regina, Larraillet, Vincent, Thalhauser, Sabrina, Graf, Tobias, Endesfelder, Manuel, Wohlrab, Stefanie

المصدر: Journal of Pharmaceutical Sciences ; ISSN 0022-3549

مصطلحات موضوعية: Pharmaceutical Science

الإتاحة: https://doi.org/10.1016/j.xphs.2023.12.018Test
https://api.elsevier.com/content/article/PII:S0022354923005452?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0022354923005452?httpAccept=text/plainTest

المؤلفون: Jensen, Pernille Foged, Schoch, Angela, Larraillet, Vincent, Hilger, Maximiliane, Schlothauer, Tilman, Emrich, Thomas, Rand, Kasper Dyrberg

المصدر: Jensen , P F , Schoch , A , Larraillet , V , Hilger , M , Schlothauer , T , Emrich , T & Rand , K D 2017 , ' A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life ' , Molecular and Cellular Proteomics , vol. 16 , no. 3 , pp. 451-456 . https://doi.org/10.1074/mcp.M116.064675Test

مصطلحات موضوعية: Antibodies, Monoclonal/chemistry, Binding Sites, Deuterium Exchange Measurement/methods, Half-Life, Histocompatibility Antigens Class I/metabolism, Humans, Hydrogen-Ion Concentration, Immunoglobulin G/chemistry, Mass Spectrometry/methods, Models, Molecular, Protein Binding, Protein Stability, Receptors, Fc/metabolism

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1074/mcp.M116.064675Test
https://curis.ku.dk/portal/da/publications/a-twopronged-binding-mechanism-of-igg-to-the-neonatal-fc-receptor-controls-complex-stability-and-igg-serum-halflifeTest(17c9172d-f7ef-40e1-8929-838b76eb8e52).html
https://curis.ku.dk/ws/files/196136206/451.full.pdfTest

المؤلفون: Walters, Benjamin T., Jensen, Pernille F., Larraillet, Vincent, Lin, Kevin, Patapoff, Thomas, Schlothauer, Tilman, Rand, Kasper D., Zhang, Jennifer

المصدر: Journal of Biological Chemistry ; volume 291, issue 4, page 1817-1825 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.m115.691568Test
https://api.elsevier.com/content/article/PII:S0021925820361160?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925820361160?httpAccept=text/plainTest

المؤلفون: Jensen, Pernille Foged, Larraillet, Vincent, Schlothauer, Tilman, Kettenberger, Hubert, Hilger, Maximiliane, Rand, Kasper D

المصدر: Jensen , P F , Larraillet , V , Schlothauer , T , Kettenberger , H , Hilger , M & Rand , K D 2015 , ' Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry ' , Molecular and Cellular Proteomics , vol. 14 , no. 1 , pp. 148-61 . https://doi.org/10.1074/mcp.M114.042044Test

الإتاحة: https://doi.org/10.1074/mcp.M114.042044Test
https://curis.ku.dk/portal/da/publications/investigating-the-interaction-between-the-neonatal-fc-receptor-and-monoclonal-antibody-variants-by-hydrogendeuterium-exchange-mass-spectrometryTest(fbc8a2f3-f58c-49fd-85ad-ff4fc3da8c18).html
http://www.mcponline.org/content/14/1/148Test

المؤلفون: Sydow, Jasmin F., Lipsmeier, Florian, Larraillet, Vincent, Hilger, Maximiliane, Mautz, Bjoern, Mølhøj, Michael, Kuentzer, Jan, Klostermann, Stefan, Schoch, Juergen, Voelger, Hans R., Regula, Joerg T., Cramer, Patrick, Papadimitriou, Apollon, Kettenberger, Hubert

المساهمون: Dübel, Stefan

المصدر: PLoS ONE ; volume 9, issue 6, page e100736 ; ISSN 1932-6203

الإتاحة: https://doi.org/10.1371/journal.pone.0100736Test