المؤلفون: Grout, John A., Sirven, Philémon, Leader, Andrew, Maskey, Shrisha, Hector, Eglantine, Puisieux, Isabelle, Steffan, Fiona, Cheng, Evan, Tung, Navpreet, Maurin, Mathieu, Vaineau, Romain, Karpf, Léa, Plaud, Martin, Begue, Anne Laure, Ganesh, Koushik, Mesple, Jérémy, Casanova-Acebes, Maria, Tabachnikova, Alexandra, Keerthivasan, Shilpa, Lansky, Alona, Le Berichel, Jessica, Walker, Laura A., Rahman, Adeeb H., Gnjatic, Sacha, Girard, Nicolas, Lefevre, Marine, Damotte, Diane, Adam, Julien, Martin, Jerôme C., Wolf, Andrea Shari, Flores, Raja M., Beasley, Mary Beth, Pradhan, Rachana N., Muller, Sören, Marron, Thomas Urban, Turley, Shannon J., Merad, Miriam M., Kenigsberg, Ephraim, Salmon, Hélène

المساهمون: Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), National Institutes of Health, NIH: S10OD026880, Genentech, Icahn School of Medicine at Mount Sinai, ISMMS, Fondation ARC pour la Recherche sur le Cancer, ARC, We thank the important contributions of patients who participated in this study. This project was supported by Genentech, Inc. and carried out in collaboration with the Fondation ARC pour la recherche sur le cancer. The computational work was supported by the Scientific Computing at the Icahn School of Medicine at Mount Sinai and the Office of Research Infrastructure of the NIH under award number S10OD026880. This manuscript was edited at Life Science Editors, and the cartoon illustrations were created using BioRender.com. We thank the Mount Sinai Flow Cytometry Core, the Human Immune Monitoring Center, and the Biorepository and Pathology Core for their support. We thank Sarah Lagha, Anne-Sophie Tedesco, Agathe Seguin-Givelet, and Isabelle Sauret for their contribution to obtaining and studying additional FFPE NSCLC samples from Institut Mutualiste Montsouris. We thank Eliane Piaggio, Ana-Maria Lennon-Duménil, and Olivier Lantz for carefully reading and commenting on the manuscript., We thank the important contributions of patients who participated in this study. This project was supported by Genentech, Inc. and carried out in collaboration with the Fondation ARC pour la recherche sur le cancer. The computational work was supported by the Scientific Computing at the Icahn School of Medicine at Mount Sinai and the Office of Research Infrastructure of the NIH under award number S10OD026880. This manuscript was edited at Life Science Editors, and the cartoon illustrations were created using BioRender.com. We thank the Mount Sinai Flow Cytometry Core, the Human Immune Monitoring Center, and the Biorepository and Pathology Core for their support. We thank Sarah Lagha, Anne-Sophie Tedesco, Agathe Seguin-Givelet, and Isabelle Sauret for their contribution to obtaining and studying additional FFPE NSCLC samples from Institut Mutualiste Montsouris. We thank Eliane Piaggio, Ana-Maria Lennon-Duménil, and Olivier Lantz for carefully reading and commenting on the manuscript. The publication costs of this article were defrayed in part by the payment of publication fees. Therefore, and solely to indicate this fact, this article is hereby marked “advertisement” in accordance with 18 USC section 1734.

المصدر: ISSN: 2159-8274 ; Cancer Discovery ; https://hal.science/hal-03888959Test ; Cancer Discovery, 2022, 12 (11), pp.2606-2625. ⟨10.1158/2159-8290.CD-21-1714⟩.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36027053; hal-03888959; https://hal.science/hal-03888959Test; https://hal.science/hal-03888959/documentTest; https://hal.science/hal-03888959/file/cd-21-1714.pdfTest; PUBMED: 36027053

الإتاحة: https://doi.org/10.1158/2159-8290.CD-21-1714Test
https://hal.science/hal-03888959Test
https://hal.science/hal-03888959/documentTest
https://hal.science/hal-03888959/file/cd-21-1714.pdfTest

المؤلفون: Beckmann, Noam D, Comella, Phillip H, Cheng, Esther, Lepow, Lauren, Beckmann, Aviva G, Tyler, Scott R, Mouskas, Konstantinos, Simons, Nicole W, Hoffman, Gabriel E, Francoeur, Nancy J, Del Valle, Diane Marie, Kang, Gurpawan, Do, Anh, Moya, Emily, Wilkins, Lillian, Le Berichel, Jessica, Chang, Christie, Marvin, Robert, Calorossi, Sharlene, Lansky, Alona, Walker, Laura, Yi, Nancy, Yu, Alex, Chung, Jonathan, Hartnett, Matthew, Eaton, Melody, Hatem, Sandra, Jamal, Hajra, Akyatan, Alara, Tabachnikova, Alexandra, Liharska, Lora E, Cotter, Liam, Fennessy, Brian, Vaid, Akhil, Barturen, Guillermo, Shah, Hardik, Wang, Ying-Chih, Sridhar, Shwetha Hara, Soto, Juan, Bose, Swaroop, Madrid, Kent, Ellis, Ethan, Merzier, Elyze, Vlachos, Konstantinos, Fishman, Nataly, Tin, Manying, Smith, Melissa, Xie, Hui, Patel, Manishkumar, Nie, Kai, Argueta, Kimberly, Harris, Jocelyn, Karekar, Neha, Batchelor, Craig, Lacunza, Jose, Yishak, Mahlet, Tuballes, Kevin, Scott, Ieisha, Kumar, Arvind, Jaladanki, Suraj, Agashe, Charuta, Thompson, Ryan, Clark, Evan, Losic, Bojan, Peters, Lauren, Mount Sinai COVID-19 Biobank Team, Roussos, Panagiotis, Zhu, Jun, Wang, Wenhui, Kasarskis, Andrew, Glicksberg, Benjamin S, Nadkarni, Girish, Bogunovic, Dusan, Elaiho, Cordelia, Gangadharan, Sandeep, Ofori-Amanfo, George, Alesso-Carra, Kasey, Onel, Kenan, Wilson, Karen M, Argmann, Carmen, Bunyavanich, Supinda, Alarcón-Riquelme, Marta E, Marron, Thomas U, Rahman, Adeeb, Kim-Schulze, Seunghee, Gnjatic, Sacha, Gelb, Bruce D, Merad, Miriam, Sebra, Robert, Schadt, Eric E, Charney, Alexander W

مصطلحات موضوعية: Adolescent, CD56 Antigen, CD57 Antigens, CD8-Positive T-Lymphocytes, COVID-19, Child, Preschool, Down-Regulation, Female, Humans, Infant, Newborn, Killer Cells, Natural, Male, Mucocutaneous Lymph Node Syndrome, SARS-CoV-2, Systemic Inflammatory Response Syndrome, Transcriptome, Young Adult

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/10668/18362Test; PMC8357784; https://www.nature.com/articles/s41467-021-24981-1.pdfTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357784/pdfTest

الإتاحة: https://doi.org/10.1038/s41467-021-24981-1Test
http://hdl.handle.net/10668/18362Test
https://www.nature.com/articles/s41467-021-24981-1.pdfTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357784/pdfTest

المؤلفون: Charney, Alexander W., Simons, Nicole W., Mouskas, Konstantinos, Lepow, Lauren, Cheng, Esther, Le Berichel, Jessica, Chang, Christie, Marvin, Robert, Del Valle, Diane Marie, Calorossi, Sharlene, Lansky, Alona, Walker, Laura, Patel, Manishkumar, Xie, Hui, Yi, Nancy, Yu, Alex, Kang, Gurpawan, Mendoza, Anthony, Liharska, Lora E., Moya, Emily, Hartnett, Matthew, Hatem, Sandra, Wilkins, Lillian, Eaton, Melody, Jamal, Hajra, Tuballes, Kevin, Chen, Steven T., Tabachnikova, Alexandra, Chung, Jonathan, Harris, Jocelyn, Batchelor, Craig, Lacunza, Jose, Yishak, Mahlet, Argueta, Kimberly, Karekar, Neha, Lee, Brian, Kelly, Geoffrey, Geanon, Daniel, Handler, Diana, Leech, John, Stefanos, Hiyab, Dawson, Travis, Scott, Ieisha, Francoeur, Nancy, Johnson, Jessica S., Vaid, Akhil, Glicksberg, Benjamin S., Nadkarni, Girish N., Schadt, Eric E., Gelb, Bruce D.

المصدر: Nature Medicine ; volume 27, issue 3, page 560-560 ; ISSN 1078-8956 1546-170X

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology, General Medicine

الإتاحة: https://doi.org/10.1038/s41591-021-01247-3Test
http://www.nature.com/articles/s41591-021-01247-3.pdfTest
http://www.nature.com/articles/s41591-021-01247-3Test

المؤلفون: Charney, Alexander W., Simons, Nicole W., Mouskas, Konstantinos, Lepow, Lauren, Cheng, Esther, Le Berichel, Jessica, Chang, Christie, Marvin, Robert, Del Valle, Diane Marie, Calorossi, Sharlene, Lansky, Alona, Walker, Laura, Patel, Manishkumar, Xie, Hui, Yi, Nancy, Yu, Alex, Kang, Gurpawan, Mendoza, Anthony, Liharska, Lora E., Moya, Emily, Hartnett, Matthew, Hatem, Sandra, Wilkins, Lillian, Eaton, Melody, Jamal, Hajra, Tuballes, Kevin, Chen, Steven T., Tabachnikova, Alexandra, Chung, Jonathan, Harris, Jocelyn, Batchelor, Craig, Lacunza, Jose, Yishak, Mahlet, Argueta, Kimberly, Karekar, Neha, Lee, Brian, Kelly, Geoffrey, Geanon, Daniel, Handler, Diana, Leech, John, Stefanos, Hiyab, Dawson, Travis, Scott, Ieisha, Francoeur, Nancy, Johnson, Jessica S., Vaid, Akhil, Glicksberg, Benjamin S., Nadkarni, Girish N., Schadt, Eric E., Gelb, Bruce D.

المصدر: Nature Medicine ; volume 26, issue 8, page 1157-1158 ; ISSN 1078-8956 1546-170X

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology, General Medicine

الإتاحة: https://doi.org/10.1038/s41591-020-1004-3Test
http://www.nature.com/articles/s41591-020-1004-3.pdfTest
http://www.nature.com/articles/s41591-020-1004-3Test

المؤلفون: Charney, Alexander W., Simons, Nicole W., Mouskas, Konstantinos, Lepow, Lauren, Cheng, Esther, Le Berichel, Jessica, Chang, Christie, Marvin, Robert, Del Valle, Diane Marie, Calorossi, Sharlene, Lansky, Alona, Walker, Laura, Patel, Manishkumar, Xie, Hui, Yi, Nancy, Yu, Alex, Kang, Gurpawan, Liharska, Lora E., Moya, Emily, Hartnett, Matthew, Hatem, Sandra, Wilkins, Lillian, Eaton, Melody, Jamal, Hajra, Tuballes, Kevin, Chen, Steven T., Chung, Jonathan, Harris, Jocelyn, Batchelor, Craig, Lacunza, Jose, Yishak, Mahlet, Argueta, Kimberly, Karekar, Neha, Lee, Brian, Kelly, Geoffrey, Geanon, Daniel, Handler, Diana, Leech, John, Stefanos, Hiyab, Dawson, Travis, Scott, Ieisha, Francoeur, Nancy, Johnson, Jessica S., Vaid, Akhil, Glicksberg, Benjamin S., Nadkarni, Girish N., Schadt, Eric E., Gelb, Bruce D., Rahman, Adeeb, Sebra, Robert

المصدر: Nature Medicine ; volume 26, issue 9, page 1493-1493 ; ISSN 1078-8956 1546-170X

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology, General Medicine

الإتاحة: https://doi.org/10.1038/s41591-020-1057-3Test
https://www.nature.com/articles/s41591-020-1057-3.pdfTest
https://www.nature.com/articles/s41591-020-1057-3Test

المؤلفون: Leader, Andrew, Grout, John, Maier, Barbara, Nabet, Barzin, Park, Matthew, Tabachnikova, Alexandra, Chang, Christie, Walker, Laura, Lansky, Alona, Le Berichel, Jessica, Troncoso, Leanna, Malissen, Nausicaa, Davila, Melanie, Martin, Jerome, Magri, Giuliana, Tuballes, Kevin, Zhao, Zhen, Petralia, Francesca, Samstein, Robert, D’amore, Natalie Roy, Thurston, Gavin, Kamphorst, Alice, Wolf, Andrea, Flores, Raja, Wang, Pei, Müller, Sören, Mellman, Ira, Beasley, Mary Beth, Salmon, Hélène, Rahman, Adeeb, Marron, Thomas, Kenigsberg, Ephraim, Merad, Miriam

المساهمون: Icahn School of Medicine at Mount Sinai New York (MSSM), Genentech, Inc. San Francisco, Service de dermatologie, vénéreologie et cancérologie cutanée Hôpital de la Timone - APHM, Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Hôpital de la Timone CHU - APHM (TIMONE), Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes (IPC), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Immunologie CHU Nantes, Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Centre de Recherche en Transplantation et Immunologie - Center for Research in Transplantation and Translational Immunology (U1064 Inserm - CR2TI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Team 1 : Mononuclear phagocytes, Immunopathology, Immunovirology (Team 1 - U1064 Inserm - CR2TI), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Takeda Pharmaceutical Co., Ltd. Tokyo, Japan (TPC), Regeneron Pharmaceuticals Inc. Tarrytown, NY, USA (RPI), R56 AI137244/AI/NIAID NIH HHS/United StatesT32 CA078207/CA/NCI NIH HHS/United StatesU24 CA210993/CA/NCI NIH HHS/United StatesR01 CA257195/CA/NCI NIH HHS/United StatesR01 CA254104/CA/NCI NIH HHS/United StatesU24 AI118644/AI/NIAID NIH HHS/United States

المصدر: ISSN: 1535-6108 ; Cancer Cell ; https://inserm.hal.science/inserm-04251063Test ; Cancer Cell, 2021, 39 (12), pp.1594-1609.e12. ⟨10.1016/j.ccell.2021.10.009⟩.

مصطلحات موضوعية: CITEseq, NSCLC, dendritic cells, high dimensional profiling, immunotherapy, macrophages, tumor cell atlas, tumor microenvironment, tumor mutational burden, tumor-associated myeloid cells, MESH: Carcinoma, Non-Small-Cell Lung / immunology, MESH: Humans, MESH: Immunotherapy / methods, MESH: Lung Neoplasms / immunology, MESH: Single-Cell Analysis / methods, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34767762; inserm-04251063; https://inserm.hal.science/inserm-04251063Test; https://inserm.hal.science/inserm-04251063/documentTest; https://inserm.hal.science/inserm-04251063/file/1-s2.0-S1535610821005602-main.pdfTest; PUBMED: 34767762; PUBMEDCENTRAL: PMC8728963

الإتاحة: https://doi.org/10.1016/j.ccell.2021.10.009Test
https://inserm.hal.science/inserm-04251063Test
https://inserm.hal.science/inserm-04251063/documentTest
https://inserm.hal.science/inserm-04251063/file/1-s2.0-S1535610821005602-main.pdfTest