المؤلفون: Wouter J. C. Feitz, Romy Bouwmeester, Thea J. A. M. van der Velden, Susan Goorden, Christoph Licht, Lambert P. J. W. van den Heuvel, Nicole C. A. J. van de Kar

المصدر: Microorganisms, Vol 9, Iss 10, p 2157 (2021)

مصطلحات موضوعية: STEC-HUS, shiga toxin, endothelial cells, globotriaosylceramide, glucosylceramide synthase, eliglustat, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2076-2607/9/10/2157Test; https://doaj.org/toc/2076-2607Test

الوصول الحر: https://doaj.org/article/494af96ddb7a437ba2b31e387ac46ae3Test

المؤلفون: Wouter J. C. Feitz, Petra A. van Setten, Thea J. A. M. van der Velden, Christoph Licht, Lambert P. J. W. van den Heuvel, Nicole C. A. J. van de Kar

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 11, p 5615 (2021)

مصطلحات موضوعية: hemolytic uremic syndrome, STEC-HUS, Shiga toxin, human glomerular microvascular endothelial cells from pediatric and adult origin, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1422-0067/22/11/5615Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test

الوصول الحر: https://doaj.org/article/6a0ba2f89edc48ab99ac87ea49291c9bTest

المؤلفون: Wouter J. C. Feitz, Nicole C. A. J. van de Kar, Ian Cheong, Thea J. A. M. van der Velden, Carolina G. Ortiz-Sandoval, Dorothea Orth-Höller, Lambert P. J. W. van den Heuvel, Christoph Licht

المصدر: Toxins, Vol 12, Iss 8, p 483 (2020)

مصطلحات موضوعية: hemolytic uremic syndrome, shiga toxin, blood outgrowth endothelial cells, Medicine

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6651/12/8/483Test; https://doaj.org/toc/2072-6651Test

الوصول الحر: https://doaj.org/article/5eb0a7aba7d740c988b3f38747293aadTest

المؤلفون: Sarah de Jong, Carel B. Hoyng, Lambert P J W van den Heuvel, Anita de Breuk, Elena B. Volokhina, Yara T. E. Lechanteur, Alejandro Garanto, Sascha Fauser, Suresh Katti, Bjorn Bakker, Anneke I. den Hollander

المصدر: Human Molecular Genetics, 31, 455-70
Human Molecular Genetics, 31, 3, pp. 455-70

مصطلحات موضوعية: Heterozygote, Mutation, Missense, Biology, Polymorphism, Single Nucleotide, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], Frameshift mutation, Macular Degeneration, Age related, Genetics, medicine, Missense mutation, Humans, In patient, Molecular Biology, Gene, Genetics (clinical), Aged, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], General Medicine, Complement System Proteins, Macular degeneration, medicine.disease, eye diseases, Complement system, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Factor H, Complement Factor H, Immunology, sense organs

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f32a9ecf69385e49c5e9c94afcf04f0Test
http://hdl.handle.net/2066/248812Test

المؤلفون: Christoph Licht, Dorothea Orth-Höller, Wouter J C Feitz, Nicole C. A. J. van de Kar, Lambert P J W van den Heuvel

المصدر: Medizinische Genetik

مصطلحات موضوعية: Microangiopathic hemolytic anemia, Alternativer Komplementweg, Complement system, Thrombotic microangiopathy, PROTEINS, 030232 urology & nephrology, Thrombotische Mikroangiopathie, 030204 cardiovascular system & hematology, urologic and male genital diseases, ALTERNATIVE PATHWAY, DISEASE, COMPLEMENT, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Atypical hemolytic uremic syndrome, Genetics, medicine, Endothelium, C3, Genetics (clinical), Loss function, REGULATORS, Genetics & Heredity, Science & Technology, MUTATIONS, business.industry, DELETION, Micro-angiopathic hemolytic anemia, medicine.disease, Komplementsystem, Human genetics, INSIGHTS, THROMBOTIC MICROANGIOPATHY, Immunology, Alternative complement pathway, Mikroangiopathische haemolytische Anaemie, business, Life Sciences & Biomedicine, Schwerpunktthema: Erbliche Nierenerkrankungen, Endothel

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0b7c3421d0adf097bacbd600220598Test
https://doi.org/10.1007/s11825-018-0216-0Test

المؤلفون: Anita de Breuk, Sarah de Jong, Lambert P J W van den Heuvel, Yara T. E. Lechanteur, Anneke I. den Hollander, Giuliana Gagliardi, Suresh Katti, Alejandro Garanto, Elena B. Volokhina

المصدر: Progress in Retinal and Eye Research, 84

مصطلحات موضوعية: 0301 basic medicine, genetic structures, Disease, Bioinformatics, Systemic circulation, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], Macular Degeneration, 03 medical and health sciences, 0302 clinical medicine, Age related, Genetic variation, Humans, Medicine, Induced pluripotent stem cell, Complement Activation, Aged, business.industry, Genetic Variation, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Complement System Proteins, Macular degeneration, medicine.disease, Sensory Systems, eye diseases, Complement system, Clinical trial, Ophthalmology, 030104 developmental biology, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030221 ophthalmology & optometry, sense organs, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f9d6315a94c3fde9720e41de5bac6dTest

المؤلفون: Nicole C. A. J. van de Kar, Lambert P J W van den Heuvel, Christoph Licht, Thea J A M van der Velden, Wouter J C Feitz, Petra van Setten

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 5615, p 5615 (2021)
International Journal of Molecular Sciences, 22
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, 22, 11

مصطلحات موضوعية: Male, 0106 biological sciences, 0301 basic medicine, Hemolytic anemia, Chemistry, Multidisciplinary, Cell, Shiga Toxin 1, 01 natural sciences, COMPLEMENT, Basal (phylogenetics), chemistry.chemical_compound, hemic and lymphatic diseases, BINDING, ASSAY, Biology (General), Cells, Cultured, Spectroscopy, Kidney, biology, STEC-HUS, Shiga toxin, General Medicine, Glomerular Mesangium, Computer Science Applications, Chemistry, medicine.anatomical_structure, ESCHERICHIA-COLI, Child, Preschool, Physical Sciences, human glomerular microvascular endothelial cells from pediatric and adult origin, Female, Tumor necrosis factor alpha, Life Sciences & Biomedicine, Bromodeoxyuridine, Adult, EXPRESSION, medicine.medical_specialty, Biochemistry & Molecular Biology, QH301-705.5, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, 010608 biotechnology, Internal medicine, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Science & Technology, Dose-Response Relationship, Drug, business.industry, Organic Chemistry, Endothelial Cells, medicine.disease, In vitro, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030104 developmental biology, Endocrinology, chemistry, Microvessels, biology.protein, hemolytic uremic syndrome, business

وصف الملف: Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a37231b5cab6fcff6c8ddc79e42ce6Test
https://doi.org/10.3390/ijms22115615Test

المؤلفون: Sascha Fauser, Chiara Suffritti, Federico Martinón-Torres, Esther Willems, Alain J. van Gool, Jeroen D. Langereis, Ronald de Groot, Jenneke J. Keizer-Garritsen, Jolein Gloerich, Laura Lorés-Motta, Renate G. van der Molen, Andrea Zanichelli, Lambert P J W van den Heuvel, Marien I. de Jonge, Anita de Breuk, Michael Levin, Michiel van der Flier, Joris van Drongelen, Elena B. Volokhina, Anneke I. den Hollander, Carel B. Hoyng, Nicole C. A. J. van de Kar, Hans J. C. T. Wessels, Jethro Herberg

المساهمون: European Commission

المصدر: Clinical & Translational Immunology, 9, 12
Clinical & Translational Immunology, 9
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Clinical & Translational Immunology

مصطلحات موضوعية: 0301 basic medicine, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], DEFICIENCIES, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], Analytical Chemistry, 0302 clinical medicine, ANGIOEDEMA, Immunology and Allergy, Multiplex, General Nursing, Mannan-binding lectin, RISK, complement‐mediated diseases, Complement Inhibitors, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], ASSOCIATION, Pathway analysis, PREVALENCE, 3. Good health, pathway analysis, 1107 Immunology, Original Article, 1115 Pharmacology and Pharmaceutical Sciences, medicine.symptom, Life Sciences & Biomedicine, Inflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5], lcsh:Immunologic diseases. Allergy, Immunology, multiplex targeted mass spectrometry, Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0], GENE POLYMORPHISMS, 03 medical and health sciences, MANNOSE-BINDING LECTIN, medicine, In patient, Clinical phenotype, complement system, Science & Technology, DYSREGULATION, Angioedema, business.industry, complement-mediated diseases, MACULAR DEGENERATION, COMPONENT, Complement system, 030104 developmental biology, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030221 ophthalmology & optometry, complementomics, complement deficiencies, business, lcsh:RC581-607

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45d46d131bec8cccd06eadc91ca7536Test
https://hdl.handle.net/2066/229301Test

المؤلفون: Victoria J. Wright, Ronald de Groot, Navin P. Boeddha, Marien I. de Jonge, Marieke Emonts, Lambert P J W van den Heuvel, Jenneke J. Keizer-Garritsen, Anouk Suppers, Irene Rivero-Calle, Elena B. Volokhina, Esther Willems, Michael Levin, Ria Philipsen, Alain J. van Gool, Renate G. van der Molen, Hans J. C. T. Wessels, Gerben Ferwerda, Wynand Alkema, Jethro Herberg, Inge M. L. Ahout, Federico Martinon Torres, Jolein Gloerich, Michiel van der Flier

المساهمون: European Commission, Imperial College London, Pediatrics

المصدر: Ebiomedicine, 45, 303-313
EBioMedicine
EBioMedicine, 45, 303. Elsevier BV
EBioMedicine, 45, 303-313. Elsevier
Ebiomedicine, 45, pp. 303-313

مصطلحات موضوعية: 0301 basic medicine, Male, Research paper, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Biochemistry, Mass Spectrometry, 0302 clinical medicine, Homeostasis, Child, Complement Activation, media_common, Infectious disease, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], General Medicine, Middle Aged, 3. Good health, C-Reactive Protein, 030220 oncology & carcinogenesis, Child, Preschool, Female, Inflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5], Adult, Complement system, Adolescent, Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0], Biology, Complement factor B, Communicable Diseases, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Classical complement pathway, Young Adult, All institutes and research themes of the Radboud University Medical Center, SDG 3 - Good Health and Well-being, media_common.cataloged_instance, Humans, European union, C-reactive protein (CRP), Inflammation, Innate immune system, Clusterin, Biochemistry, Genetics and Molecular Biology(all), Infant, Newborn, Infant, Targeted mass spectrometry, Complement System Proteins, 030104 developmental biology, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Infectious disease (medical specialty), Immunology, Multiple reaction monitoring (MRM), biology.protein, Genetics and Molecular Biology(all)

وصف الملف: application/pdf; text/plain; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f5146c96aea8518818fa71c9d9e2a9Test
http://hdl.handle.net/2066/206044Test