نتائج البحث - "LRR, Leucine-rich repeat"

1

دورية أكاديمية

Decreased Spikelets 4 Encoding a Novel Tetratricopeptide Repeat Domain-Containing Protein Is Involved in DNA Repair and Spikelet Number Determination in Rice

المؤلفون: Shen Ni, Zongzhu Li, Jiancheng Ying, Jian Zhang, Hongqi Chen

المصدر: Genes; Volume 10; Issue 3; Pages: 214

مصطلحات موضوعية: rice ( Oryza sativa L.), DNA repair, spikelet number, tetratricopeptide, LRR (leucine-rich repeat)

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Plant Genetics and Genomics; https://dx.doi.org/10.3390/genes10030214Test

الإتاحة: https://doi.org/10.3390/genes10030214Test

View record in BASE

2

Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment

المؤلفون: Bo Tang, Cunjie Chang, Guo Chen, Xiufeng Liu, Zi-Chun Hua, Xiawei Cheng, Jianxiang Chen, Heng Dong, Yiting Qiao

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3165-3177 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: PEI, polyethylenimine, NF-κB, PCR, polymerase chain reaction, 0302 clinical medicine, Salmonella, Cancer immune therapy, IFN-γ, interferon-γ, General Pharmacology, Toxicology and Pharmaceutics, TLR5, IL, interleukins, IκB, inhibitor of NF-κB, GFP, green fluorescent protein, 0303 health sciences, PD-1, programmed cell death protein-1, TIR, Toll/Interleukin-1 receptor, TME, tumor microenvironment, DN, dominant-negative, Acquired immune system, AKT, Akt serine/threonine kinase, LRR, leucine-rich repeat, PD-L1, programmed cell death-ligand 1, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, 030220 oncology & carcinogenesis, JNK, c-Jun N-terminal kinase, LPS, lipopolysaccharide, Original Article, TLR, Toll-like receptor, TRAF6, TNF receptor associated factor 6, CTLA-4, cytotoxic T-lymphocyte-associated protein 4, PBS, phosphate-buffered saline, ERKl, extracellular regulated protein kinase 1, RM1-950, Biology, CFU, colony-forming units, 03 medical and health sciences, Immune system, MyD88, myeloid differentiation factor 88, i.t., intratumorally, 030304 developmental biology, Tumor microenvironment, Flagellum, Innate immune system, Pathogen-associated molecular pattern, i.p., intraperitoneally, Immune checkpoint, NF-κB, nuclear factor kappa-B, Granzyme, ERBB2, Erb-B2 receptor tyrosine kinase 2, Cancer research, biology.protein, bacteria, Bacteria-mediated cancer therapy, Therapeutics. Pharmacology, VNP20009, Flagellin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa58001e49d3f5032ed52d1763576536Test
https://doi.org/10.1016/j.apsb.2021.04.019Test

3

Regulatory roles of ginseng on inflammatory caspases, executioners of inflammasome activation

المؤلفون: Miyong Yun, Young-Su Yi

المصدر: Journal of Ginseng Research, Vol 44, Iss 3, Pp 373-385 (2020)
Journal of Ginseng Research

مصطلحات موضوعية: 0301 basic medicine, Research areas, CARD, C-terminal caspase recruit domain, PRR, Pattern-recognition receptor, Review, Pharmacology, PGE2, Prostaglandin E2, Inflammasome, FIIND, Functional-to-find domain, Ginseng, chemistry.chemical_compound, 0302 clinical medicine, RGE, Korean Red Ginseng, lcsh:Botany, ASC, Apoptosis-associated speck-like protein containing CARD, IL, Interleukin, PAMP, Pathogen-associated molecular pattern, PYD, N-terminal pyrin domain, LPS, Lipopolysaccharide, Caspase, biology, Effector, food and beverages, GSDMD, Gasdermin D, LRR, Leucine-rich repeat, lcsh:QK1-989, Ginsenoside, 030220 oncology & carcinogenesis, medicine.symptom, Biotechnology, medicine.drug, Inflammation, Biochemistry, Genetics and Molecular Biology (miscellaneous), NO, Nitric oxide, complex mixtures, 03 medical and health sciences, COX-2, Cyclooxygenase-2, Immune system, medicine, NACHT, Nucleotide-binding and oligomerization domain, NLR, Nucleotide-binding oligomerization domain-like receptor, business.industry, DAMP, Danger-associated molecular pattern, NF-κB, Nuclear factor-kappa B, AIM2, Absent in melanoma 2, 030104 developmental biology, Complementary and alternative medicine, chemistry, Inflammatory caspase, Caspase, Cysteine aspartate–specific protease, biology.protein, HIN, Hematopoietic interferon-inducible nuclear protein, business, ROS, Reactive oxygen species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f329426609bf78cf66d558eb1ea7ae14Test
http://www.sciencedirect.com/science/article/pii/S1226845319302830Test

4

Basolateral protein Scribble binds phosphatase PP1 to establish a signaling network maintaining apicobasal polarity

المؤلفون: Regina B. Troyanovsky, Sergey M. Troyanovsky, Rei Kato, Indrajyoti Indra, Brian J. Mitchell

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Protein family, Phosphatase, Regulator, Leucine-rich repeat, ABP, apicobasal polarity, Biochemistry, Cell Line, Scribble, GEF, guanine nucleotide exchange factor, chemistry.chemical_compound, Protein Domains, Cell cortex, Humans, Molecular Biology, Tumor Suppressor Proteins, fungi, Cell Polarity, Membrane Proteins, BN-PAGE, blue native–polyacrylamide gel electrophoresis, Epithelial Cells, Cell Biology, basolateral polarity proteins, PP1, phosphatase 1, phosphatase PP1, SBP, streptavidin-binding peptide, LAP, leucine-rich repeat and PDZ domain, Cell biology, Receptors, Neuropeptide Y, LRR, leucine-rich repeat, TJ, tight junction, chemistry, SBP-tag, Guanine nucleotide exchange factor, apicobasal polarity, Protein Multimerization, Protein ligand, Protein Binding, Signal Transduction, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffc510128db201992cbbf4256e9e1dcTest
https://pubmed.ncbi.nlm.nih.gov/34634305Test

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The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies

المؤلفون: Ni Zhao, Li-Li Xu, Bin Di

المصدر: Cytokine & Growth Factor Reviews

مصطلحات موضوعية: 0301 basic medicine, ALI, acute lung injury, Inflammasomes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, MBL, mannan-binding lectin, Pathogenesis, Pyrin domain, CARD, caspase recruitment domain, 0302 clinical medicine, S/M/N/E protein, spike/membrane/nucleocapsid/envelope protein, ERK, extracellular signal-regulated kinase, NLRP3, nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3, NLRP3 inflammasomeome, Immunology and Allergy, Receptor, NF-κB, nuclear factor kappa B, COVID-19, coronavirus disease 2019, TNF, tumor necrosis factor, integumentary system, LDH, lactate dehydrogenase, Inflammasome, NEK7, never in mitosis A-related kinase 7, Cytokine, 030220 oncology & carcinogenesis, LPS, lipopolysaccharide, MAC, membrane attack complex, P2 × 7, P2X purinergic receptor 7, Cytokine Release Syndrome, medicine.drug, NETs, neutrophil extracellular traps, Inhibitor, BBB, blood-brain barrier, Immunology, MERS-CoV, middle east respiratory syndrome coronavirusus, PYD, pyrin domain, ACE2, angiotensin-converting enzyme 2, CNS, central nervous system, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, General Biochemistry, Genetics and Molecular Biology, Article, CXCL10, C-X-C motif chemokine ligand 10, Proinflammatory cytokine, LRR, leucine-rich repeat, 03 medical and health sciences, ROS, reactive oxygen species, PAMPs, pathogen-associated molecular patterns, ERGIC, endoplasmic reticulum-Golgi apparatus intermediate compartment, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Humans, ORF3a/8a/8b, open reading frame 3a/8a/8b, IFN, interferon, IL-18/1β/6/8/10/1RA, interleukin-18/1β/6/8/10/1RA, MASP2, MBL-associated serine protease 2, PKR, double-stranded RNA-dependent protein kinase, ARDS, acute respiratory distress syndrome, ComputingMethodologies_COMPUTERGRAPHICS, Ang II, angiotensin II, business.industry, SARS-CoV-2, AT1R, Ang II type 1 receptor, COVID-19, ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain, medicine.disease, Complement system, COVID-19 Drug Treatment, mtDNA, mitochondrial DNA, 030104 developmental biology, DAMPs, damage-associated molecular patterns, TMPRSS2, transmembrane serine protease 2, business, Cytokine storm, MEK, mitogen-activated protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed60731ab78b23cf231404bac5f35c0Test
https://pubmed.ncbi.nlm.nih.gov/34183243Test

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Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly

المؤلفون: Koichi Fukuda, Fan Lu, Jun Qin

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Models, Molecular, SeMet, selenomethionine, crystal structure, Protein Conformation, integrin, Integrin, Focal adhesion assembly, Leucine-rich repeat, Biochemistry, Focal adhesion, 03 medical and health sciences, cell spreading, Humans, focal adhesion, Cell adhesion, Molecular Biology, Adaptor Proteins, Signal Transducing, Focal Adhesions, kindlin, 030102 biochemistry & molecular biology, biology, Chemistry, Adhesome, Protein Stability, protein complex, Membrane Proteins, Cell Biology, LIM Domain Proteins, MAPK, Cell biology, leucine-rich repeat, ECM, extracellular matrix, ILK, integrin-linked kinase, body regions, LRR, leucine-rich repeat, 030104 developmental biology, adhesome, scaffold protein, biology.protein, Salt bridge, Hydrophobic and Hydrophilic Interactions, Rsu-1, Ras suppressor-1, HeLa Cells, Protein Binding, Transcription Factors, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa5d924acd8ef47ca53c6516db695c9Test
https://pubmed.ncbi.nlm.nih.gov/33891945Test

7

Innate immunity, inflammation activation and heat-shock protein in COVID-19 pathogenesis

المؤلفون: Hemmen Sabir, Jibrin Danladi

المصدر: Journal of neuroimmunology 358, 577632-(2021). doi:10.1016/j.jneuroim.2021.577632
Journal of Neuroimmunology

مصطلحات موضوعية: 0301 basic medicine, HSF-1, heat shock factor 1, LRR, leucine-rich repeat domain, NSAIDs, Non-steroid anti-inflammatory drugs, HSPs, heat shock proteins, Disease, Review Article, TLRs, Toll-like receptors, Pathogenesis, 0302 clinical medicine, NF-kB, nuclear factor kappa-light-chain-enhancer of activated B-cells, drug effects [SARS-CoV-2], immunology [SARS-CoV-2], Immunology and Allergy, administration & dosage [COVID-19 Vaccines], immunology [COVID-19], Vector (molecular biology), MERS-CoV, Middle East Respiratory Syndrome-corona virus, Heat-Shock Proteins, COVID-19, coronavirus disease 2019, Innate immunity, ACE2, angiotensin converting enzyme 2, Heat shock protein, HSR, heat shock response, diagnosis [Cytokine Release Syndrome], IL-6, interleukin 6, Neurology, immunology [Cytokine Release Syndrome], RBD, receptor binding domains, medicine.symptom, Cytokine Release Syndrome, COVID-19 Vaccines, Coronavirus disease 2019 (COVID-19), Immunology, drug effects [Immunity, Innate], Inflammation, Biology, prevention & control [COVID-19], prevention & control [Cytokine Release Syndrome], 03 medical and health sciences, COX-2, Cyclooxygenase-2, immunology [COVID-19 Vaccines], medicine, JAK-STAT, Janus kinase/signal transducers and activators of transcription, adverse effects [COVID-19 Vaccines], Humans, IFN, interferon, SARS, severe acute respiratory syndrome, PG, prostaglandin, ddc:610, GSDMD, gasdermin D, ARDS, acute respiratory distress syndrome, Innate immune system, IFN-γ, interferon gamma, SARS-CoV-2, IRF3, interferon regulatory factor 3, TNF-α, tumor necrosis factor-alpha, immunology [Heat-Shock Proteins], COVID-19, ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain, biochemical phenomena, metabolism, and nutrition, medicine.disease, diagnosis [COVID-19], Immunity, Innate, NLRP3 inflammasome, immunology [Immunity, Innate], 030104 developmental biology, Neurology (clinical), MRRs, microbial recognition receptors, Cytokine storm, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe94851777aa41431356f58c238b2f7Test

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The diverse roles of RIP kinases in host-pathogen interactions

المؤلفون: Vik Ven Eng, Madeleine A. Wemyss, Jaclyn S. Pearson

المصدر: Seminars in Cell & Developmental Biology

مصطلحات موضوعية: NSA, necrosulfonamide, T4SS, type IV secretion system, RHIM, RIP homotypic interaction motif, ERK, extracellular signal-regulated kinases, MDP, muramyl dipeptide, TNF, tumour necrosis factor, RIP kinase, 0302 clinical medicine, UPR, unfolded protein response, RIG-I, cytosolic retinoic acid-inducible gene I, T3SS, type III secretion system, TGFβ, transforming growth factor beta, AEC, airway epithelial cell, MCMV, murine cytomegalovirus, NP, nucleoprotein, ZBP1, Z-DNA binding protein, Kgp, lysine-specific protease gingipain, COTV, Cotia poxvirus, COVID-19, coronavirus disease 2019, XIAP, X-linked inhibitor of apoptosis protein, ALRs, AIM2-like receptors, KD, kinase domain, Kinase, Th1, T helper 1, BMDMs, bone marrow-derived macrophages, HFMD, hand foot and mouth disease, BclxL, Bcl-extra large, TRAM, translocating chain-associated membrane protein, dsRNA, double stranded RNA, LMP1, latent membrane protein, Cell biology, Intracellular signal transduction, CARD, caspase activation and recruitment domain, SDH, succinate dehydrogenase, TRPM7, transient receptor potential cation channel subfamily M member 7, IKK, IĸB kinase, MAVS, mitochondrial antiviral signaling proteins, NK, natural killer, TRIF, TIR-domain-containing adapter-inducing interferon-β, ISGF3, IFN-stimulated gene factor 3, Cell signaling, AIM2, absent in melanoma 2, PD, Parkinson disease, Yop, Yersinia outer protein, JEV, Japanese encephalitis virus, Poly(I:C), polyinosinic:polycytidylic acid, Article, PKR, protein kinase R, vIRA, viral inhibitor of RIP activation, RIPK2, 03 medical and health sciences, RIPK1, BAV, BeAn 58058 poxvirus, NLRs, nucleotide-binding domain–like receptors, ORF, open reading frame, IAV, influenza A virus, MyD88, myeloid differentiation factor 88, CD, Crohn’s disease, Humans, SARS, severe acute respiratory syndrome, DAMPs, danger-associated molecular patterns, GSDMD, gasdermin D, TLR, toll-like receptor, UL45/UL48, human CMV envelope protein 45/48, RR, ribonucleotide reductase, OMV, outer membrane vesicle, NO, nitric oxide, Pathogen-associated molecular pattern, TRAILR, TNF-related apoptosis-inducing ligand receptor, COR, C-terminal of Roc, DR, death receptor, GEF, guanidine exchange factor, IĸB, inhibitor of ĸB, WT, wild-type, Saporins, HMGB1, high mobility group box 1, IL, interleukin, MDA5, melanoma differentiation-associated protein 5, 030104 developmental biology, siRNA, small interfering RNA, TBK1, TANK-binding kinase 1, PFT, pore-forming toxins, ISGs, interferon stimulated genes, Cif, cycle inhibiting factor, RSV, respiratory syncytial virus, TRADD, TNFR1-associated death domain protein, Bacterial infection, PAMPs, pathogen associated molecular patterns, 030217 neurology & neurosurgery, Developmental Biology, 0301 basic medicine, NSP, non-structural protein, Bcl-2, B-cell lymphoma 2, CA6, coxsackievirus A6, DENV, dengue virus, E3L, vaccinia virus protein E3 long, TAK1, TGFβ-activated kinase 1, iE-DAP, Ɣ-d-glutamyl-mesodiaminopimelic acid, AP-1, activator protein 1, vICA, viral inhibitor of caspase-8 activation, ZIKV, Zika virus, HIV-1, human immunodeficiency virus type 1, PI3K, PI3 kinase, ATG16L1, autophagy-related 16-like 1, CVB, coxsackievirus B3, PRRs, pattern recognition receptors, SNPs (line 657) ssRNA, single-stranded RNA, MAPKs, mitogen-activated protein kinases, Pathogen, HSV, Herpes simplex virus, DAI, DNA-dependent activator of IRFs, EBV, Epstein-Barr virus, M45, murine CMV virion associated protein M45, PGN, bacterial peptidoglycan, DAP, diaminopimelic acid, UBE2N, ubiquitin-conjugating enzyme E2N, ID, intermediate domain, NleB, non-LEE encoded effector protein B, c-FLIP, cellular FLICE inhibitory protein, DRP1, dynamin-related protein 1, vMLKL, viral MLKL-like proteins, IRG1, immunoresponsive gene 1, LRR, leucine-rich repeat, NF-ĸB, nuclear factor-ĸB, TNFR1, TNF receptor type 1, WNV, West Nile virus, HCV, hepatitis C virus, JNK, c-Jun N-terminal kinase, Host-Pathogen Interactions, LPS, lipopolysaccharide, Roc, Ras-of-complex, PVM, pneumonia virus of mice, NET, neutrophil extracellular traps, HAEC, human aortic endothelial cells, ASC, apoptosis-associated speck-like protein, NLRC4, NLR family CARD domain containing 4, SARS-3a, SARS-CoV ORF protein 3a, Cell death, VSV, vesicular stomatitis virus, PnCW, pneumococcal cell wall, RIPKs, receptor interacting protein kinases, Mtb, Mycobacterium tuberculosis, HBeAg, hepatitis B e antigen, Biology, CNS, central nervous system, cIAPs, cellular inhibitor of apoptosis proteins, ER, endoplasmic reticulum, IFI44L, IFN-induced protein 44-like, NOD, nucleotide-binding oligomerization domain, ROS, reactive oxygen species, DISCs, death-inducing signaling complexes, NoV, norovirus, 3Cpro, viral non-structural protein 3C, IFN, interferon, VV, vaccinia virus, PR, protease, TRAF, TNFR associated factors, Inflammation, CNF1, cytotoxic necrotising factor 1, HCMV, human cytomegalovirus, KO, knockout, NLRP3, NLR family pyrin domain containing 3, Nec-1, necrostatin-1, Autophagy, IRFs, IFN regulatory factors, Cell Biology, CMV, cytomegalovirus, MLKL, mixed-lineage kinase-domain like protein, HPV, human papilloma virus, NAIPs, NLR family apoptosis inhibitory proteins, HBV, hepatitis B virus, PI3P, phosphatidylinositol 3-phosphate, RDA, RIPK1-dependent apoptosis, Viral infection, MKKs, MAPK kinases, LUBAC, linear ubiquitin chain assembly complex, BVDV, bovine viral diarrhoea virus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628bb448c2d6de5b9d7755cdadd35794Test
http://europepmc.org/articles/PMC7448748Test

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USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates

المؤلفون: Fengwu Zhang, Yongchao Zhao, Yi Sun

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Immunoprecipitation, Leucine-rich repeat, APC/C, anaphase-promoting complex/cyclosome, Biochemistry, RING, really interesting new gene, SKP1-Cullin1-F-box E3 (SCF E3), CCK-8, cell counting kit-8, Protein Domains, Ubiquitin, Cell Line, Tumor, DUB, deubiquitylase, Enzyme Stability, SKP2, Humans, IB, immunoblotting, ubiquitylation, S-Phase Kinase-Associated Proteins, Molecular Biology, Gene knockdown, SCF, SKP1-Cullin1-F-box, biology, Chemistry, USP2, ubiquitin-specific proteases 2, Ubiquitination, IP, immunoprecipitation, Cell Biology, deubiquitylation, MDM2, mouse double minute 2 homolog, Ubiquitin ligase, Cell biology, USP2, BCR-ABL, break-point cluster region-Abelson, FBXW7, F-box/WD repeat–containing protein 7, LRR, leucine-rich repeat, Proteasome, biology.protein, Mdm2, Ubiquitin Thiolesterase, Cyclin-Dependent Kinase Inhibitor p27, Research Article, SKP2, S-phase kinase-associated protein 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fea3e86bcf91811f1a20b21f9c1f35Test
https://doi.org/10.1016/j.jbc.2021.101109Test

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Decreased Spikelets 4 Encoding a Novel Tetratricopeptide Repeat Domain-Containing Protein Is Involved in DNA Repair and Spikelet Number Determination in Rice

المؤلفون: Hongqi Chen, Jiancheng Ying, Shen Ni, Zongzhu Li, Jian Zhang

المصدر: Genes, Vol 10, Iss 3, p 214 (2019)
Genes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214814e54233a83a762f1097d952b73fTest
http://www.mdpi.com/2073-4425/10/3/214Test

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