المؤلفون: Lorenzo, Petra I, Cobo-Vuilleumier, Nadia, Martín-Vázquez, Eugenia, López-Noriega, Livia, Gauthier, Benoit R

مصطلحات موضوعية: HMG20A, LRH-1/NR52A, PAX4, diabetes, redifferentiation, regeneration, single-cell transcriptomics, transdifferentiation, β-cell heterogeneity, Animals, Cell Transdifferentiation, Diabetes Mellitus, Type 1, Humans, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Regenerative Medicine

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/10668/17697Test; PMC8073058; https://www.mdpi.com/1422-0067/22/8/4239/pdf?version=1618973075Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073058/pdfTest

الإتاحة: https://doi.org/10.3390/ijms22084239Test
http://hdl.handle.net/10668/17697Test
https://www.mdpi.com/1422-0067/22/8/4239/pdf?version=1618973075Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073058/pdfTest

المؤلفون: Petra I. Lorenzo, Nadia Cobo-Vuilleumier, Eugenia Martín-Vázquez, Livia López-Noriega, Benoit R. Gauthier

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 8; Pages: 4239

مصطلحات موضوعية: diabetes, regeneration, β-cell heterogeneity, transdifferentiation, redifferentiation, single-cell transcriptomics, PAX4, LRH-1/NR52A, HMG20A

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/ijms22084239Test

الإتاحة: https://doi.org/10.3390/ijms22084239Test

المؤلفون: Benoit R. Gauthier, Petra I. Lorenzo, Nadia Cobo-Vuilleumier, Livia López-Noriega, Eugenia Martín-Vázquez

المساهمون: Junta de Andalucía, Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, European Commission, Juvenile Diabetes Research Foundation, Fundación Vencer el Cancer, Asociación Lucha y Sonríe por la Vida (España), Fundación DiabetesCERO, Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España)

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4239, p 4239 (2021)

مصطلحات موضوعية: 0301 basic medicine, LRH-1/NR52A, transdifferentiation, medicine.medical_treatment, Review, Bioinformatics, Regenerative Medicine, 0302 clinical medicine, Insulin-Secreting Cells, Glucose homeostasis, Insulin, Biology (General), Spectroscopy, geography.geographical_feature_category, diabetes, Transdifferentiation, β-cell heterogeneity, General Medicine, Islet, Computer Science Applications, Chemistry, medicine.anatomical_structure, QH301-705.5, 030209 endocrinology & metabolism, Catalysis, Inorganic Chemistry, 03 medical and health sciences, Islets of Langerhans, Diabetes mellitus, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, geography, PAX4, business.industry, Pancreatic islets, Regeneration (biology), Organic Chemistry, medicine.disease, redifferentiation, 030104 developmental biology, Diabetes Mellitus, Type 1, regeneration, Cell Transdifferentiation, HMG20A, business, single-cell transcriptomics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965e230b6623cb1b4291d5f1551249feTest
http://europepmc.org/articles/PMC8073058Test

المؤلفون: Lorenzo, Petra I., Cobo-Vuilleumier, Nadia, Martín-Vázquez, Eugenia, López-Noriega, Livia, Gauthier, Benoit R.

المساهمون: Junta de Andalucía, Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, European Commission, Juvenile Diabetes Research Foundation, Fundación Vencer el Cancer, Asociación Lucha y Sonríe por la Vida (España), Fundación DiabetesCERO, Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), [Lorenzo,PI, Cobo-Vuilleumier,N, Martín-Vázquez,E, López-Noriega,L, Gauthier,BR] Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain. [Gauthier,BR] Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., Authors were/are funded by grants from Consejería de Salud, Fundación Pública Andaluza Progreso y Salud, Junta de Andalucía (PI-0727-2010, December 2010 to B.R.G., PI-0085-2013, December 2013 to P.I.L., and PI-0001-2020, December 2020 to B.R.G. and P.I.L.), Consejería de Economía, Innovación y Ciencia, Junta de Andalucía (P10-CTS-6359 to B.R.G.), Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, cofunded by Fondos FEDER (PI10/00871, January 2011 and PI13/00593, January 2014 to B.R.G.), Ministerio de Economía y Competitividad, Plan Nacional (BFU2017-83588-P, January 2018 to B.R.G. and PRE2018-084907, January 2018 to E.M.-V.), Juvenile Diabetes Research Foundation JDRF (17-2013-372, August 2013 and 2-SRA-2019-837-S-B, August 2019 to B.R.G:), and Fundacion Vencer el Cancer (to B.R.G.). Special thanks to ALUSVI (Asociación Lucha y Sonríe por la Vida, Pilas), a local Andalusian association, and the Fundacion DiabetesCero for their unconditional financial support.

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
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مصطلحات موضوعية: Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings], Redifferentiation, LRH-1/NR52A, Regeneración, Transdiferenciación, Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 1 [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Transcription, Genetic::Transcriptome [Medical Subject Headings], Diabetes mellitus, Células secretoras de insulina, Organisms::Eukaryota::Animals [Medical Subject Headings], Homeostasis, Regeneration, Anatomy::Endocrine System::Enteroendocrine Cells::Insulin-Secreting Cells [Medical Subject Headings], Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Insulins [Medical Subject Headings], Transdifferentiation, PAX4, Diabetes, β-cell heterogeneity, Singlecell transcriptomics, Disciplines and Occupations::Health Occupations::Medicine::Regenerative Medicine [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents [Medical Subject Headings], HMG20A, Single-cell transcriptomics, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Transdifferentiation [Medical Subject Headings], Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose::Blood Glucose [Medical Subject Headings]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bc8ae500c6b07c20c52cb5ac248faae5Test
http://hdl.handle.net/10261/259444Test