دورية أكاديمية

Androgenetic alopecia in transgender and gender diverse populations: A review of therapeutics

التفاصيل البيبلوغرافية
العنوان: Androgenetic alopecia in transgender and gender diverse populations: A review of therapeutics
المؤلفون: Gao, Julia L, Streed, Carl G, Thompson, Julie, Dommasch, Erica D, Peebles, Jon Klinton
المصدر: GW Authored Works
بيانات النشر: Health Sciences Research Commons
سنة النشر: 2023
المجموعة: George Washington University: Health Sciences Research Commons (HSRC)
مصطلحات موضوعية: FTM, LGBT, LLLLT, LLLT, MTF, PRP, alopecia, androgenetic alopecia, bisexual, dermatology, dutasteride, finasteride, gay, gender diversity, gender identity disorder, gender minority, gender queer, gender-diverse, general dermatology, hair loss, hair restoration procedure, hairline advancement, hairline transplantation, health disparities, lesbian, low-level laser light therapy, medical dermatology, minoxidil, platelet-rich plasma, sexual minority
الوصف: Androgenetic alopecia (AGA) management is a significant clinical and therapeutic challenge for transgender and gender-diverse (TGD) patients. Although gender-affirming hormone therapies affect hair growth, there is little research about AGA in TGD populations. After reviewing the literature on approved treatments, off-label medication usages, and procedures for treating AGA, we present treatment options for AGA in TGD patients. The first-line treatments for any TGD patient include topical minoxidil 5% applied to the scalp once or twice daily, finasteride 1 mg oral daily, and/or low-level laser light therapy. Spironolactone 200 mg daily is also first-line for transfeminine patients. Second-line options include daily oral minoxidil dosed at 1.25 or 2.5 mg for transfeminine and transmasculine patients, respectively. Topical finasteride 0.25% monotherapy or in combination with minoxidil 2% solution are second-line options for transmasculine and transfeminine patients, respectively. Other second-line treatments for any TGD patient include oral dutasteride 0.5 mg daily, platelet-rich plasma, or hair restoration procedures. After 6-12 months of treatment, AGA severity and treatment progress should be assessed via scales not based on sex; eg, the Basic and Specific Classification or the Bouhanna scales. Dermatologists should coordinate care with the patient's primary gender-affirming clinician(s) so that shared knowledge of all medications exists across the care team.
نوع الوثيقة: text
اللغة: unknown
العلاقة: https://hsrc.himmelfarb.gwu.edu/gwhpubs/3710Test; https://doi.org/10.1016/j.jaad.2021.08.067Test
DOI: 10.1016/j.jaad.2021.08.067
الإتاحة: https://doi.org/10.1016/j.jaad.2021.08.067Test
https://hsrc.himmelfarb.gwu.edu/gwhpubs/3710Test
رقم الانضمام: edsbas.C7C0C8E1
قاعدة البيانات: BASE