المؤلفون: Senftleber, Ninna Karsbæk, Andersen, Mette K., Jørsboe, Emil, Stæger, Frederik Filip, Nøhr, Anne Krogh, Garcia-Erill, Genis, Meisner, Jonas, Santander, Cindy G., Balboa, Renzo F., Gilly, Arthur, Bjerregaard, Peter, Larsen, Christina Viskum Lytken, Grarup, Niels, Jørgensen, Marit Eika, Zeggini, Eleftheria, Moltke, Ida, Hansen, Torben, Albrechtsen, Anders

المصدر: Senftleber , N K , Andersen , M K , Jørsboe , E , Stæger , F F , Nøhr , A K , Garcia-Erill , G , Meisner , J , Santander , C G , Balboa , R F , Gilly , A , Bjerregaard , P , Larsen , C V L , Grarup , N , Jørgensen , M E , Zeggini , E , Moltke , I , Hansen , T & Albrechtsen , A 2024 , ' GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 ....

مصطلحات موضوعية: Cardiovascular Diseases/genetics, Cholesterol, HDL, LDL/genetics, Genome-Wide Association Study, Greenland, Humans, Lipids/genetics, Polymorphism, Single Nucleotide, Proprotein Convertase 9/genetics, Triglycerides/genetics

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/742ff7de-b9f1-4929-b920-fffb1a71e19dTest

الإتاحة: https://doi.org/10.1038/s41431-023-01485-8Test
https://portal.findresearcher.sdu.dk/da/publications/742ff7de-b9f1-4929-b920-fffb1a71e19dTest
https://findresearcher.sdu.dk/ws/files/255818891/s41431-023-01485-8.pdfTest

المؤلفون: Hedegaard, Berit Storgaard, Bork, Christian Sørensen, Kanstrup, Helle Lynge, Thomsen, Kristian Korsgaard, Heitmann, Merete, Bang, Lia Evi, Henriksen, Finn Lund, Andersen, Lars Juel, Gohr, Thomas, Mouridsen, Mette Rauhe, Soja, Anne Merete Boas, Elpert, Frank-Peter, Jakobsen, Tomas Joen, Sjøl, Anette, Joensen, Albert Marni, Nordestgaard, Børge Grønne, Klausen, Ib Christian, Schmidt, Erik Berg

المصدر: Hedegaard , B S , Bork , C S , Kanstrup , H L , Thomsen , K K , Heitmann , M , Bang , L E , Henriksen , F L , Andersen , L J , Gohr , T , Mouridsen , M R , Soja , A M B , Elpert , F-P , Jakobsen , T J , Sjøl , A , Joensen , A M , Nordestgaard , B G , Klausen , I C & Schmidt , E B 2023 , ' Genetic testing increases the likelihood of a diagnosis of familial ....

مصطلحات موضوعية: Cholesterol, LDL/genetics, Denmark/epidemiology, Genetic Testing, Humans, Hyperlipoproteinemia Type II/diagnosis, Referral criteria, Familial hypercholesterolaemia, Cardiovascular disease, Lipid clinics, LDL cholesterol

العلاقة: https://pure.au.dk/portal/da/publications/genetic-testing-increases-the-likelihood-of-a-diagnosis-of-familial-hypercholesterolaemia-among-people-referred-to-lipid-clinicsTest(04844d4d-7d62-4001-be48-a0bf2be5b838).html

الإتاحة: https://doi.org/10.1016/j.atherosclerosis.2023.04.003Test
https://pure.au.dk/portal/da/publications/genetic-testing-increases-the-likelihood-of-a-diagnosis-of-familial-hypercholesterolaemia-among-people-referred-to-lipid-clinicsTest(04844d4d-7d62-4001-be48-a0bf2be5b838).html
http://www.scopus.com/inward/record.url?scp=85152707351&partnerID=8YFLogxKTest

المؤلفون: Faquih, Tariq O, Aziz, N. Ahmad, Dijk, Ko Willems, Mook-Kanamori, Dennis O, Gardiner, Sarah L, Li-Gao, Ruifang, de Mutsert, Renée, Milaneschi, Yuri, Trompet, Stella, Jukema, J Wouter, Rosendaal, Frits R, Hylckama Vlieg, Astrid

المصدر: Human molecular genetics 32(10), 1741-1752 (2023). doi:10.1093/hmg/ddad020

مصطلحات موضوعية: info:eu-repo/classification/ddc/570, Humans, Body Mass Index, Diabetes Mellitus, Type 2: genetics, Reference Values, Huntingtin Protein: genetics, Huntington Disease: pathology, Lipoproteins, LDL: genetics, Trinucleotide Repeat Expansion: genetics, Huntingtin Protein, LDL, HTT protein, human

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/pmid:36715614; info:eu-repo/semantics/altIdentifier/issn/0964-6906; info:eu-repo/semantics/altIdentifier/issn/1460-2083; https://pub.dzne.de/record/248107Test; https://pub.dzne.de/search?p=id:%22DZNE-2023-00211%22Test

الإتاحة: https://doi.org/10.1093/hmg/ddad020Test
https://pub.dzne.de/record/248107Test
https://pub.dzne.de/search?p=id:%22DZNE-2023-00211%22Test

المؤلفون: Xia, Kailin, Klose, Veronika, Högel, Josef, Huang, Tao, Zhang, Linjing, Dorst, Johannes, Fan, Dongsheng, Ludolph, Albert C

المصدر: European journal of neurology 30(7), 1899 - 1906 (2023). doi:10.1111/ene.15810

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Humans, Amyotrophic Lateral Sclerosis: epidemiology, Amyotrophic Lateral Sclerosis: genetics, Cholesterol, LDL: genetics, Mendelian Randomization Analysis, Genome-Wide Association Study, Risk Factors, Polymorphism, Single Nucleotide, Triglycerides: genetics, Mendelian randomization, amyotrophic lateral sclerosis, genetics, instrumental variables, lipids, LDL, Triglycerides

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/pmid:36999624; info:eu-repo/semantics/altIdentifier/issn/1351-5101; info:eu-repo/semantics/altIdentifier/issn/1468-1331; https://pub.dzne.de/record/258246Test; https://pub.dzne.de/search?p=id:%22DZNE-2023-00592%22Test

الإتاحة: https://doi.org/10.1111/ene.15810Test
https://pub.dzne.de/record/258246Test
https://pub.dzne.de/search?p=id:%22DZNE-2023-00592%22Test

المساهمون: Hyoeun Kim, Chan Joo Lee, Sang-Hyun Kim, Jang Young Kim, Sung Hee Choi, Hyun-Jae Kang, Kyong Soo Park, Byung Ryul Cho, Byung Jin Kim, Ki Chul Sung, In-Kyung Jeong, Jin-Ok Jeong, Jang-Whan Bae, Jung Mi Park, Yunbeom Lee, Ilecheon Jeong, Hyojun Han, Ji Hyun Lee, Sang-Hak Lee, Lee, Snag Hak

مصطلحات موضوعية: Cholesterol, LDL / genetics, DNA Copy Number Variations, Humans, Hyperlipoproteinemia Type II* / diagnosis, Hyperlipoproteinemia Type II* / epidemiology, Hyperlipoproteinemia Type II* / genetics, Mutation, Phenotype, Receptors, Registries, Republic of Korea / epidemiology, Xanthomatosis* / epidemiology, Xanthomatosis* / genetics, Diagnosis, Far East, Hyperlipoproteinemia type II

وصف الملف: application/pdf

العلاقة: JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS; J01252; OAK-2022-07147; OAK-2022-07148; https://ir.ymlib.yonsei.ac.kr/handle/22282913/191847Test; T202203111; JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, Vol.29(8) : 1,176-1,187, 2022-08

الإتاحة: https://doi.org/10.5551/jat.63062Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/191847Test

المؤلفون: Seneviratne, Anusha, Cave, Luke, Hyde, Gareth, Moestrup, Soren Kragh, Carling, David, Mason, Justin C., Haskard, Dorian O., Boyle, Joseph James

المصدر: Seneviratne , A , Cave , L , Hyde , G , Moestrup , S K , Carling , D , Mason , J C , Haskard , D O & Boyle , J J 2021 , ' Metformin directly suppresses atherosclerosis in normoglycaemic mice via haematopoietic adenosine monophosphate-activated protein kinase ' , Cardiovascular Research , vol. 117 , no. 5 , pp. 1295-1308 . https://doi.org/10.1093/cvr/cvaa171Test

مصطلحات موضوعية: AMPK, Atherosclerosis, Gene expression, Macrophage, Metformin, Transcription factor, ACCELERATED ATHEROSCLEROSIS, BONE-MARROW-TRANSPLANTATION, MACROPHAGES, TRANSCRIPTION, RECEPTOR, HEART-DISEASE, HEME, PATHWAY, MONOCYTE SUBSETS, EXPRESSION, Phosphorylation, Humans, Aortic Diseases/enzymology, Aorta/drug effects, Atherosclerosis/enzymology, Receptors, LDL/genetics, AMP-Activated Protein Kinases/genetics, Disease Models, Animal, Signal Transduction, Metformin/pharmacology, Cells, Cultured

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1093/cvr/cvaa171Test
https://pure.au.dk/portal/da/publications/metformin-directly-suppresses-atherosclerosis-in-normoglycaemic-mice-via-haematopoietic-adenosine-monophosphateactivated-protein-kinaseTest(85ce7ecf-04fc-41c3-957e-86935662d77a).html
https://pure.au.dk/ws/files/274450570/cvaa171.pdfTest
http://www.scopus.com/inward/record.url?scp=85104037249&partnerID=8YFLogxKTest

المؤلفون: Berit Storgaard Hedegaard, Christian Sørensen Bork, Helle Lynge Kanstrup, Kristian Korsgaard Thomsen, Merete Heitmann, Lia Evi Bang, Finn Lund Henriksen, Lars Juel Andersen, Thomas Gohr, Mette Rauhe Mouridsen, Anne Merete Boas Soja, Frank-Peter Elpert, Tomas Joen Jakobsen, Anette Sjøl, Albert Marni Joensen, Børge Grønne Nordestgaard, Ib Christian Klausen, Erik Berg Schmidt

المصدر: Hedegaard, B S, Bork, C S, Kanstrup, H L, Thomsen, K K, Heitmann, M, Bang, L E, Henriksen, F L, Andersen, L J, Gohr, T, Mouridsen, M R, Soja, A M B, Elpert, F-P, Jakobsen, T J, Sjøl, A, Joensen, A M, Nordestgaard, B G, Klausen, I C & Schmidt, E B 2023, ' Genetic testing increases the likelihood of a diagnosis of familial hypercholesterolaemia among people referred to lipid clinics : Danish national study ', Atherosclerosis, vol. 373, pp. 10-16 . https://doi.org/10.1016/j.atherosclerosis.2023.04.003Test

مصطلحات موضوعية: Cholesterol, LDL/genetics, Hyperlipoproteinemia Type II/diagnosis, LDL cholesterol, Referral criteria, Humans, Genetic Testing, Cardiology and Cardiovascular Medicine, Cardiovascular disease, Familial hypercholesterolaemia, Denmark/epidemiology, Lipid clinics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128247a656cb46a6b40278a39f8ac015Test
https://pure.au.dk/portal/da/publications/genetic-testing-increases-the-likelihood-of-a-diagnosis-of-familial-hypercholesterolaemia-among-people-referred-to-lipid-clinicsTest(04844d4d-7d62-4001-be48-a0bf2be5b838).html

المؤلفون: Sibbeliene E. van den Bosch, Willemijn E. Corpeleijn, Barbara A. Hutten, Albert Wiegman

المصدر: van den Bosch, S E, Corpeleijn, W E, Hutten, B A & Wiegman, A 2023, ' How Genetic Variants in Children with Familial Hypercholesterolemia Not Only Guide Detection, but Also Treatment ', Genes, vol. 14, no. 3, 669 . https://doi.org/10.3390/genes14030669Test

مصطلحات موضوعية: Homozygous Familial Hypercholesterolemia, Proprotein Convertase 9/genetics, lipid-lowering therapy, familial hypercholesterolemia, LDL/genetics, cholesterol, genetic screening, lipids, Hyperlipoproteinemia Type II/diagnosis, Cardiovascular Diseases/genetics, Genetics, Humans, Carrier Proteins, Child, Genetics (clinical), Angiopoietin-Like Protein 3

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc56fbc06c15caa0ff02bb3f975e73ffTest
https://doi.org/10.3390/genes14030669Test

المؤلفون: Kilpeläinen, T.O., Bentley, A.R., Noordam, R., Sung, Y.J., Schwander, K., Winkler, T.W., Jakupović, H., Chasman, D.I., Manning, A., Ntalla, I., Aschard, H., Brown, M.R., de Las Fuentes, L., Franceschini, N., Guo, X., Vojinovic, D., Aslibekyan, S., Feitosa, M.F., Kho, M., Musani, S.K., Richard, M., Wang, H., Wang, Z., Bartz, T.M., Bielak, L.F., Campbell, A., Dorajoo, R., Fisher, V., Hartwig, F.P., Horimoto, ARVR, Li, C., Lohman, K.K., Marten, J., Sim, X., Smith, A.V., Tajuddin, S.M., Alver, M., Amini, M., Boissel, M., Chai, J.F., Chen, X., Divers, J., Evangelou, E., Gao, C., Graff, M., Harris, S.E., He, M., Hsu, F.C., Jackson, A.U., Zhao, J.H., Kraja, A.T., Kühnel, B., Laguzzi, F., Lyytikäinen, L.P., Nolte, I.M., Rauramaa, R., Riaz, M., Robino, A., Rueedi, R., Stringham, H.M., Takeuchi, F., van der Most, P.J., Varga, T.V., Verweij, N., Ware, E.B., Wen, W., Li, X., Yanek, L.R., Amin, N., Arnett, D.K., Boerwinkle, E., Brumat, M., Cade, B., Canouil, M., Chen, Y.I., Concas, M.P., Connell, J., de Mutsert, R., de Silva, H.J., de Vries, P.S., Demirkan, A., Ding, J., Eaton, C.B., Faul, J.D., Friedlander, Y., Gabriel, K.P., Ghanbari, M., Giulianini, F., Gu, C.C., Gu, D., Harris, T.B., He, J., Heikkinen, S., Heng, C.K., Hunt, S.C., Ikram, M.A., Jonas, J.B., Koh, W.P., Komulainen, P., Krieger, J.E., Kritchevsky, S.B., Kutalik, Z., Kuusisto, J., Langefeld, C.D., Langenberg, C., Launer, L.J., Leander, K., Lemaitre, R.N., Lewis, C.E., Liang, J., Liu, J., Mägi, R., Manichaikul, A., Meitinger, T., Metspalu, A., Milaneschi, Y., Mohlke, K.L., Mosley, T.H., Murray, A.D., Nalls, M.A., Nang, E.K., Nelson, C.P., Nona, S., Norris, J.M., Nwuba, C.V., O'Connell, J., Palmer, N.D., Papanicolau, G.J., Pazoki, R., Pedersen, N.L., Peters, A., Peyser, P.A., Polasek, O., Porteous, D.J., Poveda, A., Raitakari, O.T., Rich, S.S., Risch, N., Robinson, J.G., Rose, L.M., Rudan, I., Schreiner, P.J., Scott, R.A., Sidney, S.S., Sims, M., Smith, J.A., Snieder, H., Sofer, T., Starr, J.M., Sternfeld, B., Strauch, K., Tang, H., Taylor, K.D., Tsai, M.Y., Tuomilehto, J., Uitterlinden, A.G., van der Ende, M.Y., van Heemst, D., Voortman, T., Waldenberger, M., Wennberg, P., Wilson, G., Xiang, Y.B., Yao, J., Yu, C., Yuan, J.M., Zhao, W., Zonderman, A.B., Becker, D.M., Boehnke, M., Bowden, D.W., de Faire, U., Deary, I.J., Elliott, P., Esko, T., Freedman, B.I., Froguel, P., Gasparini, P., Gieger, C., Kato, N., Laakso, M., Lakka, T.A., Lehtimäki, T., Magnusson, PKE, Oldehinkel, A.J., Penninx, BWJH, Samani, N.J., Shu, X.O., van der Harst, P., Van Vliet-Ostaptchouk, J.V., Vollenweider, P., Wagenknecht, L.E., Wang, Y.X., Wareham, N.J., Weir, D.R., Wu, T., Zheng, W., Zhu, X., Evans, M.K., Franks, P.W., Gudnason, V., Hayward, C., Horta, B.L., Kelly, T.N., Liu, Y., North, K.E., Pereira, A.C., Ridker, P.M., Tai, E.S., van Dam, R.M., Fox, E.R., Kardia, SLR, Liu, C.T., Mook-Kanamori, D.O., Province, M.A., Redline, S., van Duijn, C.M., Rotter, J.I., Kooperberg, C.B., Gauderman, W.J., Psaty, B.M., Rice, K., Munroe, P.B., Fornage, M., Cupples, L.A., Rotimi, C.N., Morrison, A.C., Rao, D.C., Loos, RJF

المساهمون: Lifelines Cohort Study, Alizadeh, B.Z., Boezen, H.M., Franke, L., Navis, G., Rots, M., Swertz, M., Wolffenbuttel, BHR, Wijmenga, C.

المصدر: Nature communications, vol. 10, no. 1, pp. 376

مصطلحات موضوعية: Adolescent, Adult, African Continental Ancestry Group/genetics, Aged, 80 and over, Asian Continental Ancestry Group/genetics, Brazil, Calcium-Binding Proteins/genetics, Cholesterol/blood, Cholesterol, HDL/blood, HDL/genetics, LDL/blood, LDL/genetics, European Continental Ancestry Group/genetics, Exercise, Female, Genetic Loci/genetics, Genome-Wide Association Study, Genotype, Hispanic Americans/genetics, Humans, LIM-Homeodomain Proteins/genetics, Lipid Metabolism/genetics, Lipids/blood, Lipids/genetics, Male, Membrane Proteins/genetics, Microtubule-Associated Proteins/genetics, Middle Aged

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30670697; info:eu-repo/semantics/altIdentifier/eissn/2041-1723; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_1B8EF42248BA4; https://serval.unil.ch/notice/serval:BIB_1B8EF42248BATest; urn:issn:2041-1723; https://serval.unil.ch/resource/serval:BIB_1B8EF42248BA.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1B8EF42248BA4Test

الإتاحة: https://doi.org/10.1038/s41467-018-08008-wTest
https://serval.unil.ch/notice/serval:BIB_1B8EF42248BATest
https://serval.unil.ch/resource/serval:BIB_1B8EF42248BA.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1B8EF42248BA4Test

المؤلفون: Zarei, M., Barroso, E., Palomer, X., Dai, J., Rada, P., Quesada-López, T., Escolà-Gil, J.C., Cedó, L., Zali, M.R., Molaei, M., Dabiri, R., Vázquez, S., Pujol, E., Valverde, Á.M., Villarroya, F., Liu, Y., Wahli, W., Vázquez-Carrera, M.

المصدر: Molecular metabolism, vol. 8, pp. 117-131

مصطلحات موضوعية: Activating Transcription Factor 4/genetics, Activating Transcription Factor 4/metabolism, Animals, Cell Line, Tumor, Female, Fibroblast Growth Factors/genetics, Fibroblast Growth Factors/metabolism, Humans, Liver/metabolism, Male, Mice, Inbred C57BL, Non-alcoholic Fatty Liver Disease/metabolism, PPAR delta/genetics, PPAR delta/metabolism, PPAR-beta/genetics, PPAR-beta/metabolism, Receptors, LDL/genetics, LDL/metabolism, Signal Transduction, eIF-2 Kinase/genetics, eIF-2 Kinase/metabolism, ATF4, ER stress, FGF21, PPAR, VLDLR

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29289645; info:eu-repo/semantics/altIdentifier/eissn/2212-8778; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_4C931839E09D1; https://serval.unil.ch/notice/serval:BIB_4C931839E09DTest; urn:issn:2212-8778; https://serval.unil.ch/resource/serval:BIB_4C931839E09D.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4C931839E09D1Test

الإتاحة: https://doi.org/10.1016/j.molmet.2017.12.008Test
https://serval.unil.ch/notice/serval:BIB_4C931839E09DTest
https://serval.unil.ch/resource/serval:BIB_4C931839E09D.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4C931839E09D1Test