المؤلفون: Shenol, Aslihan, Lückmann, Michael, Trauelsen, Mette, Lambrughi, Matteo, Tiberti, Matteo, Papaleo, Elena, Frimurer, Thomas M., Schwartz, Thue W.

المصدر: Shenol , A , Lückmann , M , Trauelsen , M , Lambrughi , M , Tiberti , M , Papaleo , E , Frimurer , T M & Schwartz , T W 2024 , ' Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91 ' , Molecular Cell , vol. 84 , no. 5 , pp. 955-966 . https://doi.org/10.1016/j.molcel.2024.01.011Test

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/769bf276-566c-4522-b306-c5fb094a8677Test

الإتاحة: https://doi.org/10.1016/j.molcel.2024.01.011Test
https://orbit.dtu.dk/en/publications/769bf276-566c-4522-b306-c5fb094a8677Test
https://backend.orbit.dtu.dk/ws/files/355654576/1-s2.0-S1097276524000479-main.pdfTest

المؤلفون: Lückmann, Michael, Shenol, Aslihan, Nissen, Tinne A.D., Petersen, Jacob E., Kouvchinov, David, Schwartz, Thue W., Frimurer, Thomas M.

المصدر: Lückmann , M , Shenol , A , Nissen , T A D , Petersen , J E , Kouvchinov , D , Schwartz , T W & Frimurer , T M 2022 , ' Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action ' , ACS Medicinal Chemistry Letters , vol. 13 , no. 12 , pp. 1839-1847 . https://doi.org/10.1021/acsmedchemlett.2c00160Test

مصطلحات موضوعية: FFAR1, FFAR4, free fatty acid receptor, G-protein-coupled receptor, GPR120, GPR40

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1021/acsmedchemlett.2c00160Test
https://curis.ku.dk/portal/da/publications/optimization-of-firstinclass-dualacting-ffar1ffar4-allosteric-modulators-with-novel-mode-of-actionTest(c7c3f34a-40c6-4e53-9b1d-fb4b67a37899).html
https://curis.ku.dk/ws/files/329287729/acsmedchemlett.2c00160.pdfTest

المؤلفون: Lückmann, Michael, Trauelsen, Mette, Bentsen, Marie A., Nissen, Tinne A. D., Martins, Joao, Fallah, Zohreh, Nygaard, Mads M., Papaleo, Elena, Lindorff-Larsen, Kresten, Schwartz, Thue W., Frimurer, Thomas M.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2019 Apr 01. 116(14), 7123-7128.

الوصول الحر: https://www.jstor.org/stable/26698621Test

المؤلفون: Mende, Franziska, Hundahl, Cecilie, Plouffe, Bianca, Skov, Louise Julie, Sivertsen, Bjørn, Madsen, Andreas Nygaard, Lückmann, Michael, Diep, Thi Ai, Offermanns, Stefan, Frimurer, Thomas Michael, Bouvier, Michel, Holst, Birgitte

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2018 Oct . 115(43), E10255-E10264.

الوصول الحر: https://www.jstor.org/stable/26532400Test

المؤلفون: Kjær, Viktoria M. S., Ieremias, Loukas, Daugvilaite, Viktorija, Lückmann, Michael, Frimurer, Thomas M., Ulven, Trond, Rosenkilde, Mette M., Våbenø, Jon

المصدر: ChemMedChem ; volume 16, issue 17, page 2623-2627 ; ISSN 1860-7179 1860-7187

الإتاحة: https://doi.org/10.1002/cmdc.202100301Test

المؤلفون: Smit, Florent X., van der Velden, Wijnand J.C., Kizilkaya, Hüsün S., Nørskov, Amalie, Lückmann, Michael, Hansen, Tobias N., Sparre-Ulrich, Alexander H., Qvotrup, Katrine, Frimurer, Thomas M., Rosenkilde, Mette M.

المساهمون: Carlsbergfondet, Novo Nordisk Foundation

المصدر: Structure ; volume 29, issue 7, page 679-693.e6 ; ISSN 0969-2126

مصطلحات موضوعية: Molecular Biology, Structural Biology

الإتاحة: https://doi.org/10.1016/j.str.2021.04.001Test
https://api.elsevier.com/content/article/PII:S0969212621001179?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0969212621001179?httpAccept=text/plainTest

المؤلفون: Jørgensen, Astrid S., Larsen, Olav, Uetz-von Allmen, Edith, Lückmann, Michael, Legler, Daniel F., Frimurer, Thomas M., Veldkamp, Christopher T., Hjortø, Gertrud M., Rosenkilde, Mette M.

المصدر: Frontiers in Immunology. 2019, 10, 2156. eISSN 1664-3224. Available under: doi:10.3389/fimmu.2019.02156

مصطلحات موضوعية: ligand biased signaling, CCR7, CCL21, CCL19, chemokine core domain, ECL2, ddc:570

وصف الملف: application/pdf

العلاقة: http://nbn-resolving.de/urn:nbn:de:bsz:352-2-14a6gxbyb03e89Test; http://dx.doi.org/10.3389/fimmu.2019.02156Test

الإتاحة: https://doi.org/10.3389/fimmu.2019.02156Test
http://nbn-resolving.de/urn:nbn:de:bsz:352-2-14a6gxbyb03e89Test

المؤلفون: Lückmann, Michael, van der Velden, Wijnand Jacobus C, Oliva-Santiago, Marta, Brvar, Matjaz, Ulven, Trond, Frimurer, Thomas Michael, Karlshøj, Stefanie, Rosenkilde, Mette Marie, Larsen, Olav Ditlevsen

المصدر: Lückmann , M , van der Velden , W J C , Oliva-Santiago , M , Brvar , M , Ulven , T , Frimurer , T M , Karlshøj , S , Rosenkilde , M M & Larsen , O D 2019 , ' Selective Allosteric Modulation of N‑Terminally Cleaved, but Not Full Length CCL3 in CCR1 ' , ACS Pharmacology & Translational Science , vol. 2 , no. 6 , pp. 429-441 . https://doi.org/10.1021/acsptsci.9b00059Test

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/0e8fc46e-60fc-417e-9482-264fe9d9d409Test

الإتاحة: https://doi.org/10.1021/acsptsci.9b00059Test
https://portal.findresearcher.sdu.dk/da/publications/0e8fc46e-60fc-417e-9482-264fe9d9d409Test
https://findresearcher.sdu.dk/ws/files/170261280/Selective_allosteric_modulation_of_N_terminally_cleaved_but_not_full_length_CCL3_in_CCR1.pdfTest

المؤلفون: Larsen, Olav, Lückmann, Michael, van der Velden, Wijnand J.C., Oliva-Santiago, Marta, Brvar, Matjaz, Ulven, Trond, Frimurer, Thomas M, Karlshøj, Stefanie, Rosenkilde, Mette M

المصدر: Larsen , O , Lückmann , M , van der Velden , W J C , Oliva-Santiago , M , Brvar , M , Ulven , T , Frimurer , T M , Karlshøj , S & Rosenkilde , M M 2019 , ' Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1 ' , ACS Pharmacology & Translational Science , vol. 2 , no. 6 , pp. 429-441 . https://doi.org/10.1021/acsptsci.9b00059Test

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1021/acsptsci.9b00059Test
https://curis.ku.dk/portal/da/publications/selective-allosteric-modulation-of-nterminally-cleaved-but-not-full-length-ccl3-in-ccr1Test(c4360730-53a0-4057-be4e-53526931aba0).html
https://curis.ku.dk/ws/files/256509964/acs.nanolett.8b03733.pdfTest

المؤلفون: Rexen Ulven, Elisabeth, Trauelsen, Mette, Brvar, Matjaz, Lückmann, Michael, Bielefeldt, Line, Jensen, Lisa K.I., Schwartz, Thue W., Frimurer, Thomas M.

المصدر: Rexen Ulven , E , Trauelsen , M , Brvar , M , Lückmann , M , Bielefeldt , L , Jensen , L K I , Schwartz , T W & Frimurer , T M 2018 , ' Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1 ' , Scientific Reports , vol. 8 , 10010 . https://doi.org/10.1038/s41598-018-28263-7Test

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/7bff92c3-16f7-41ed-b18c-06ed946c71f3Test

الإتاحة: https://doi.org/10.1038/s41598-018-28263-7Test
https://portal.findresearcher.sdu.dk/da/publications/7bff92c3-16f7-41ed-b18c-06ed946c71f3Test
https://findresearcher.sdu.dk/ws/files/141831374/Structure_Activity_Investigations_and_Optimisations_of_Non_metabolite_Agonists_for_the_Succinate_Receptor_1.pdfTest