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1دورية أكاديمية
المؤلفون: Frederique Chaperon, Markus Fendt, Peter H Kelly, Kurt Lingenhoehl, Johannes Mosbacher, Hans-Rudolf Olpe, Peter Schmid, Christine Sturchler, Kevin H McAllister, P Herman van der Putten, Christine E Gee
المصدر: PLoS ONE, Vol 7, Iss 4, p e34963 (2012)
وصف الملف: electronic resource
العلاقة: http://europepmc.org/articles/PMC3324554?pdf=renderTest; https://doaj.org/toc/1932-6203Test
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2دورية أكاديمية
المؤلفون: Lidong Liu, Tak Pan Wong, Mario F Pozza, Kurt Lingenhoehl, Yushan Wang, Morgan Sheng, Yves P Auberson, Yu Tian Wang
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
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3Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist
المؤلفون: David Orain, Kurt Lingenhoehl, Sandrine Desrayaud, David Carcache, Joerg Kallen, Anne Picard, Stephan Urwyler, Phillip Floersheim, Engin Tasdelen, Manuel Koller, Celine Dubois, Samuel Haessig, Henri Mattes
المصدر: ChemMedChem. 12:197-201
مصطلحات موضوعية: 0301 basic medicine, Selurampanel, Administration, Oral, AMPA receptor, Molecular Dynamics Simulation, Pharmacology, Crystallography, X-Ray, Binding, Competitive, Biochemistry, Mice, Structure-Activity Relationship, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Seizures, Drug Discovery, medicine, Animals, Potency, Receptors, AMPA, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Quinazolinones, chemistry.chemical_classification, Electroshock, Sulfonamides, Binding Sites, Organic Chemistry, Glutamate receptor, Antagonist, medicine.disease, Protein Structure, Tertiary, Sulfonamide, Disease Models, Animal, 030104 developmental biology, chemistry, Drug Design, Molecular Medicine, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8af42b315e5498d295c341f87f15e14Test
https://doi.org/10.1002/cmdc.201600467Test -
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المؤلفون: Stephan Urwyler, Kurt Lingenhoehl, David Carcache, Yves Auberson, Joerg Kallen, Henri Mattes, Silvio Ofner, Markus Schmutz, Ivan-Toma Vranesic, Manuel Koller, David Orain
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:3358-3361
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, AMPA receptor, Pharmacology, Crystallography, X-Ray, Binding, Competitive, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Structure–activity relationship, Receptors, AMPA, Receptor, Molecular Biology, Quinazolinones, Sulfonamides, Molecular Structure, Chemistry, Organic Chemistry, Sulfonamide (medicine), Glutamate receptor, Antagonist, Biological activity, Rats, Molecular Medicine, Anticonvulsants, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d693f1d01624fea9d7743c668cfcbdTest
https://doi.org/10.1016/j.bmcl.2011.04.017Test -
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المؤلفون: David Orain, Markus Schmutz, Henri Mattes, Yves Auberson, Johanne Renaud, Kurt Lingenhoehl, Hans Kalkman
المصدر: Recent Patents on CNS Drug Discovery. 1:247-259
مصطلحات موضوعية: Epilepsy, Multiple Sclerosis, Therapeutic effectiveness, Pain, Biology, Anxiety Disorders, Patents as Topic, Psychiatry and Mental health, Neuroprotective Agents, Drug Discovery, Schizophrenia, Animals, Humans, Pharmacology (medical), Receptors, AMPA, AMPA Receptor Antagonists, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02880917e168b38624cf8eef9e4bfd3Test
https://doi.org/10.2174/157488906778773698Test -
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المؤلفون: Yushan Wang, Kurt Lingenhoehl, Mario F. Pozza, Yu Tian Wang, Tak Pan Wong, Lidong Liu, Morgan Sheng, Yves Auberson
المصدر: Science. 304:1021-1024
مصطلحات موضوعية: Multidisciplinary, Synaptic fatigue, nervous system, Chemistry, musculoskeletal, neural, and ocular physiology, Synaptic augmentation, Synaptic plasticity, Metaplasticity, NMDA receptor, Long-term potentiation, Neurotransmission, Long-term depression, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::70b063035018bc9c3f4f129328c5d9aeTest
https://doi.org/10.1126/science.1096615Test -
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المؤلفون: Conrad Gentsch, Klemens Kaupmann, Will Spooren, John F. Cryan, Bernhard Bettler, Frederique Chaperon, Peter H. Kelly, Kurt Lingenhoehl, Cedric Mombereau, Wolfgang Froestl
المصدر: Journal of Pharmacology and Experimental Therapeutics. 310:952-963
مصطلحات موضوعية: Male, Agonist, Baclofen, Elevated plus maze, Pentobarbital, Time Factors, Fever, medicine.drug_class, Cyclopentanes, Motor Activity, GABAB receptor, Pharmacology, Body Temperature, Chlordiazepoxide, Rats, Sprague-Dawley, Benzodiazepines, Mice, chemistry.chemical_compound, Stress, Physiological, Traction, Avoidance Learning, medicine, Animals, Maze Learning, GABA Agonists, Mice, Inbred BALB C, Benzodiazepine, Rats, Drug Combinations, Pyrimidines, Muscle relaxation, Anti-Anxiety Agents, Receptors, GABA-B, nervous system, chemistry, GABA-B Receptor Agonists, Rotarod Performance Test, Molecular Medicine, Psychology, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479ff5a3903f911e009ea120d043ebf6Test
https://doi.org/10.1124/jpet.104.066753Test -
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المؤلفون: Hans Allgeier, Yves Auberson, Serge Bischoff, Robert Moretti, Markus Schmutz, Kurt Lingenhoehl
المصدر: Bioorganic & Medicinal Chemistry Letters. 12:1099-1102
مصطلحات موضوعية: medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Binding, Competitive, Receptors, N-Methyl-D-Aspartate, Biochemistry, Mice, chemistry.chemical_compound, Quinoxalines, Drug Discovery, Convulsion, medicine, Animals, Humans, Receptor, Molecular Biology, PEAQX, Molecular Structure, Chemistry, Organic Chemistry, Antagonist, Glutamate receptor, Electric Stimulation, Anticonvulsant Agent, Anticonvulsant, Molecular Medicine, NMDA receptor, Anticonvulsants, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fecb5ad689d26f852fbaad439bd45f1Test
https://doi.org/10.1016/s0960-894xTest(02)00074-4 -
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المؤلفون: Phillip Floersheim, Celine Dubois, Anne Picard, David Orain, Joerg Kallen, Manuel Koller, Kurt Lingenhoehl, Engin Tasdelen, Sandrine Desrayaud, David Carcache, Stephan Urwyler, Henri Mattes, Samuel Haessig
المصدر: ChemMedChem. 12:196-196
مصطلحات موضوعية: Pharmacology, Selurampanel, Chemistry, Organic Chemistry, Glutamate receptor, Antagonist, AMPA receptor, Biochemistry, Orally active, Drug Discovery, Molecular Medicine, Cover (algebra), General Pharmacology, Toxicology and Pharmaceutics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::132b0e2341c7eba107b91794239e2364Test
https://doi.org/10.1002/cmdc.201600627Test -
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المؤلفون: Johannes Mosbacher, Klemens Kaupmann, Stephan Urwyler, Jakob Heid, Bernhard Bettler, Karin Hofstetter, Kurt Lingenhoehl, Wolfgang Froestl
المصدر: Molecular Pharmacology. 60:963-971
مصطلحات موضوعية: Pharmacology, Agonist, GTP', medicine.drug_class, Chemistry, Stereochemistry, Chinese hamster ovary cell, Allosteric regulation, GABAB receptor, gamma-Aminobutyric acid, nervous system, Metabotropic glutamate receptor, medicine, Molecular Medicine, Receptor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::732df28dba87c9a76e79e0ce7dc5b326Test
https://doi.org/10.1124/mol.60.5.963Test