المؤلفون: Borst, Gerben R, Kumareswaran, Ramya, Yücel, Hatice, Telli, Seyda, Do, Trevor, McKee, Trevor, Zafarana, Gaetano, Jonkers, Jos, Verheij, Marcel, O'Connor, Mark J, Rottenberg, Sven, Bristow, Robert G

المصدر: Borst, Gerben R; Kumareswaran, Ramya; Yücel, Hatice; Telli, Seyda; Do, Trevor; McKee, Trevor; Zafarana, Gaetano; Jonkers, Jos; Verheij, Marcel; O'Connor, Mark J; Rottenberg, Sven; Bristow, Robert G (2017). Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model. OncoTarget, 8(50), pp. 87638-87646. Impact Journals LLC 10.18632/oncotarget.20936

مصطلحات موضوعية: 570 Life sciences, biology, 610 Medicine & health, 630 Agriculture

وصف الملف: application/pdf

العلاقة: https://boris.unibe.ch/112033Test/

الإتاحة: https://doi.org/10.18632/oncotarget.20936Test
https://boris.unibe.ch/112033/1/20936-299517-4-PB.pdfTest
https://boris.unibe.ch/112033Test/

المؤلفون: Guturi, Kiran Kumar Naidu, Bohgaki, Miyuki, Bohgaki, Toshiyuki, Srikumar, Tharan, Ng, Deborah, Kumareswaran, Ramya, El Ghamrasni, Samah, Jeon, Justin, Patel, Parasvi, Eldin, Mohamed Saad, Bristow, Rob, Cheung, Peter, Stewart, Grant S., Raught, Brian, Hakem, Anne, Hakem, Razqallah

المصدر: Guturi , K K N , Bohgaki , M , Bohgaki , T , Srikumar , T , Ng , D , Kumareswaran , R , El Ghamrasni , S , Jeon , J , Patel , P , Eldin , M S , Bristow , R , Cheung , P , Stewart , G S , Raught , B , Hakem , A & Hakem , R 2016 , ' RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation ' , Nature Communications , vol. 7 , 12638 . https://doi.org/10.1038/ncomms12638Test

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1038/ncomms12638Test
https://research.manchester.ac.uk/en/publications/ef8d3adc-5352-43ac-b4ce-7f053bd72197Test
http://www.scopus.com/inward/record.url?scp=84983739186&partnerID=8YFLogxKTest

المؤلفون: Lohse, Ines, Kumareswaran, Ramya, Cao, Pinjiang, Pitcher, Bethany, Gallinger, Steven, Bristow, Robert G., Hedley, David W.

المصدر: Lohse , I , Kumareswaran , R , Cao , P , Pitcher , B , Gallinger , S , Bristow , R G & Hedley , D W 2016 , ' Effects of combined treatment with ionizing radiation and the PARP inhibitor olaparib in BRCA mutant and wild type patient-derived pancreatic cancer xenografts ' , PLoS ONE , vol. 11 , no. 12 , e0167272 . https://doi.org/10.1371/journal.pone.0167272Test

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1371/journal.pone.0167272Test
https://research.manchester.ac.uk/en/publications/1f0e34ef-d713-4607-a374-8474778386d6Test
http://www.scopus.com/inward/record.url?scp=85007413318&partnerID=8YFLogxKTest

المؤلفون: Borst, Gerben R, Kumareswaran, Ramya, Yücel, Hatice, Telli, Seyda, Do, Trevor, McKee, Trevor, Zafarana, Gaetano, Jonkers, Jos, Verheij, Marcel, O'Connor, Mark J, Rottenberg, Sven, Bristow, Robert G

المصدر: Borst , G R , Kumareswaran , R , Yücel , H , Telli , S , Do , T , McKee , T , Zafarana , G , Jonkers , J , Verheij , M , O'Connor , M J , Rottenberg , S & Bristow , R G 2020 , ' Correction : Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model ' , Oncotarget , vol. 11 , no. 17 , pp. 1573-1574 . https://doi.org/10.18632/oncotarget.27476Test

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.18632/oncotarget.27476Test
https://research.manchester.ac.uk/en/publications/45602618-c2bc-49b5-924a-c2d7ae81fdecTest

المؤلفون: Dal Pra, Alan, Berlin, Alejandro, Kumareswaran, Ramya, Schattner, Ariah Joshua, Craig, Tim, Wong, David, Hodgson, David, Fischer, Sandra E., Bristow, Robert G., Dawson, Laura A.

المصدر: Dal Pra , A , Berlin , A , Kumareswaran , R , Schattner , A J , Craig , T , Wong , D , Hodgson , D , Fischer , S E , Bristow , R G & Dawson , L A 2016 , ' Liver failure after abdominal irradiation : Identifying the right suspects ' , Journal of Clinical Oncology , vol. 34 , no. 9 , pp. e80-e83 . https://doi.org/10.1200/JCO.2013.50.9547Test

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1200/JCO.2013.50.9547Test
https://research.manchester.ac.uk/en/publications/7d2eda5c-3199-4833-b0b2-a0fd0daa65b6Test
http://www.scopus.com/inward/record.url?scp=84962147357&partnerID=8YFLogxKTest

المؤلفون: Kumareswaran, Ramya, Chaudary, Naz, Jaluba, Karolina, Meng, Alice, Sykes, Jenna, Borhan, Asm, Hill, Richard P., Bristow, Robert G.

المصدر: Kumareswaran , R , Chaudary , N , Jaluba , K , Meng , A , Sykes , J , Borhan , A , Hill , R P & Bristow , R G 2015 , ' Cyclic hypoxia does not alter RAD51 expression or PARP inhibitor cell kill in tumor cells ' , Radiotherapy and Oncology , vol. 116 , no. 3 , pp. 388-391 . https://doi.org/10.1016/j.radonc.2015.03.027Test

مصطلحات موضوعية: Cyclic hypoxia, DNA repair, PARP inhibition, RAD51, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1016/j.radonc.2015.03.027Test
https://research.manchester.ac.uk/en/publications/bc97fc1e-6672-4e85-bef8-e05f7982cd01Test
http://www.scopus.com/inward/record.url?scp=84944175966&partnerID=8YFLogxKTest

المؤلفون: Gani, Cihan, Coackley, Carla, Kumareswaran, Ramya, Schütze, Christina, Krause, Mechthild, Zafarana, Gaetano, Bristow, Robert G.

المصدر: Gani , C , Coackley , C , Kumareswaran , R , Schütze , C , Krause , M , Zafarana , G & Bristow , R G 2015 , ' In vivo studies of the PARP inhibitor, AZD-2281, in combination with fractionated radiotherapy : An exploration of the therapeutic ratio ' , Radiotherapy and Oncology , vol. 116 , no. 3 , pp. 486-494 . https://doi.org/10.1016/j.radonc.2015.08.003Test

مصطلحات موضوعية: AZD-2281, Clonogenic assay, EF5, Gamma H2AX, Growth delay, Gut toxicity, PARP inhibitors, Prostate cancer, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1016/j.radonc.2015.08.003Test
https://research.manchester.ac.uk/en/publications/0f1e87ad-b944-4991-9438-33dcc5b155acTest
http://www.scopus.com/inward/record.url?scp=84944162662&partnerID=8YFLogxKTest

المؤلفون: Chan, Norman, Ali, Mohsin, McCallum, Gordon P., Kumareswaran, Ramya, Koritzinsky, Marianne, Wouters, Bradly G., Wells, Peter G., Gallinger, Steven, Bristow, Robert G.

المصدر: Chan , N , Ali , M , McCallum , G P , Kumareswaran , R , Koritzinsky , M , Wouters , B G , Wells , P G , Gallinger , S & Bristow , R G 2014 , ' Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells ' , Molecular Cancer Research , vol. 12 , no. 10 , pp. 1407-1415 . https://doi.org/10.1158/1541-7786.MCR-14-0246Test

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1158/1541-7786.MCR-14-0246Test
https://research.manchester.ac.uk/en/publications/2413bdc7-13e7-4339-b3a0-fa306e10efcdTest
http://www.scopus.com/inward/record.url?scp=84907978015&partnerID=8YFLogxKTest

المؤلفون: Luoto, Kaisa R, Kumareswaran, Ramya, Bristow, Robert G

العلاقة: Genome Integrity. 2013 Oct 24;4(1):5; http://dx.doi.org/10.1186/2041-9414-4-5Test; http://hdl.handle.net/1807/86616Test

الإتاحة: https://doi.org/10.1186/2041-9414-4-5Test
http://hdl.handle.net/1807/86616Test

المؤلفون: Kumareswaran, Ramya, Ludkovski, Olga, Meng, Alice, Sykes, Jenna, Pintilie, Melania, Bristow, Robert G.

المصدر: Kumareswaran , R , Ludkovski , O , Meng , A , Sykes , J , Pintilie , M & Bristow , R G 2012 , ' Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability ' , Journal of Cell Science , vol. 125 , no. 1 , pp. 189-199 . https://doi.org/10.1242/jcs.092262Test

مصطلحات موضوعية: γ-H2AX, DNA double-strand break sensors, DNA double-strand breaks, Genetic instability, Hypoxia, Non-homologous end joining, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1242/jcs.092262Test
https://research.manchester.ac.uk/en/publications/8ae8e5f3-327d-430f-80c4-097cd0ba17cfTest
http://www.scopus.com/inward/record.url?scp=84858119890&partnerID=8YFLogxKTest