المؤلفون: Bay, Yasmin, Egeberg Jeppesen, Mie, Frydenvang, Karla, Francotte, Pierre, Pirotte, Bernard, Pickering, Darryl S., Kristensen, Anders Skov, Kastrup, Jette Sandholm

المصدر: Bay , Y , Egeberg Jeppesen , M , Frydenvang , K , Francotte , P , Pirotte , B , Pickering , D S , Kristensen , A S & Kastrup , J S 2024 , ' The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2 ' , FEBS Letters , vol. 598 , no. 7 , pp. 743-757 . https://doi.org/10.1002/1873-3468.14824Test

مصطلحات موضوعية: BPAM344 binding mode, calcium-sensitive fluorescence-based assay, dimer interface, GluK2 mutations, positive allosteric modulation, X-ray crystallography

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1002/1873-3468.14824Test
https://curis.ku.dk/portal/da/publications/the-positive-allosteric-modulator-bpam344-and-lglutamate-introduce-an-activelike-structure-of-the-ligandbinding-domain-of-gluk2Test(edc0b943-651d-4436-ac37-82f7e06d37e7).html
https://curis.ku.dk/ws/files/387737935/FEBS_Letters_2024_Bay_The_positive_allosteric_modulator_BPAM344_and_L_glutamate_introduce_an_active_like_structure_of.pdfTest

المؤلفون: Chałupnik, Paulina, Vialko, Alina, Pickering, Darryl, Nielsen, Birgitte, Bay, Yasmin, Kristensen, Anders Skov, Hinkkanen, Markus, Szczepańska, Katarzyna, Karcz, Tadeusz, Latacz, Gniewomir, Johansen, Tommy, Szymanska, Ewa

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.60731/ujcm.230524Test
https://portalwiedzy.cm-uj.krakow.pl/info/report/UJCMc4d7b0fcdd314acaae1b5a654cc1621bTest/

المؤلفون: Francotte, Pierre, Bay, Yasmin, Goffin, Eric, Colson, Thomas, Lesenfants, Cindy, Dorosz, Jerzy, Laulumaa, Saara, Fraikin, Pierre, de Tullio, Pascal, Beaufour, Caroline, Botez, Iuliana, Pickering, Darryl S., Frydenvang, Karla, Danober, Laurence, Kristensen, Anders Skov, Kastrup, Jette Sandholm, Pirotte, Bernard

المصدر: Francotte , P , Bay , Y , Goffin , E , Colson , T , Lesenfants , C , Dorosz , J , Laulumaa , S , Fraikin , P , de Tullio , P , Beaufour , C , Botez , I , Pickering , D S , Frydenvang , K , Danober , L , Kristensen , A S , Kastrup , J S & Pirotte , B 2024 , ' Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators ' , ....

مصطلحات موضوعية: 1,2,4-Benzothiadiazine 1,1-dioxides, Calcium-sensitive fluorescence-based assay, Ionotropic glutamate receptors, Positive allosteric modulators, thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxides, X-ray crystallography

الإتاحة: https://doi.org/10.1016/j.ejmech.2023.116036Test
https://curis.ku.dk/portal/da/publications/exploring-thienothiadiazine-dioxides-as-isosteric-analogues-of-benzo-and-pyridothiadiazine-dioxides-in-the-search-of-new-ampa-and-kainate-receptor-positive-allosteric-modulatorsTest(4ff101cd-50ac-44e4-8b8c-dfcfe8ce4852).html

المؤلفون: Chałupnik, Paulina, Vialko, Alina, Pickering, Darryl S., Nielsen, Birgitte, Bay, Yasmin, Kristensen, Anders Skov, Hinkkanen, Markus, Szczepańska, Katarzyna, Karcz, Tadeusz, Latacz, Gniewomir, Johansen, Tommy N., Szymańska, Ewa

العلاقة: ChemMedChem, T. 18, nr 18; https://ruj.uj.edu.pl/xmlui/handle/item/316936Test

الإتاحة: https://doi.org/10.1002/cmdc.202300278Test
https://ruj.uj.edu.pl/xmlui/handle/item/316936Test

المؤلفون: Chalupnik, Paulina, Vialko, Alina, Pickering, Darryl S, Nielsen, Birgitte, Bay, Yasmin, Kristensen, Anders Skov, Hinkkanen, Markus, Szczepańska, Katarzyna, Karcz, Tadeusz, Latacz, Gniewomir, Johansen, Tommy Nørskov, Szymanska, Ewa

المصدر: Chalupnik , P , Vialko , A , Pickering , D S , Nielsen , B , Bay , Y , Kristensen , A S , Hinkkanen , M , Szczepańska , K , Karcz , T , Latacz , G , Johansen , T N & Szymanska , E 2023 , ' Structure-activity relationship and solubility studies of N1 substituted quinnoxaline-2,3-diones as kainate receptor antagonists ' , chemmedchem.org . https://doi.org/10.1002/cmdc202300278Test

الإتاحة: https://doi.org/10.1002/cmdc202300278Test
https://curis.ku.dk/portal/da/publications/structureactivity-relationship-and-solubility-studies-of-n1-substituted-quinnoxaline23diones-as-kainate-receptor-antagonistsTest(06d15a2f-3434-48b9-a5b9-da68940e34ea).html

المؤلفون: Rannversson, Hafsteinn, Wilson, Pamela, Kristensen, Kristina Birch, Sinning, Steffen, Kristensen, Anders Skov, Strømgaard, Kristian, Andersen, Jacob

المصدر: Journal of Biological Chemistry ; volume 290, issue 23, page 14582-14594 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.m114.629071Test
https://api.elsevier.com/content/article/PII:S0021925819795180?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925819795180?httpAccept=text/plainTest

المؤلفون: Thøgersen, Lucy Kate Ladefoged, Schiøtt, Birgit, Munro, Lachlan Jake, Kristensen, Anders Skov

المصدر: Thøgersen , L K L , Schiøtt , B , Munro , L J & Kristensen , A S 2019 , ' Molecular Insight into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-HT3A Receptors ' , pp. 479A . < https://www.cell.com/biophysj/pdf/S0006-3495Test(18)33851-7.pdf >

العلاقة: https://pure.au.dk/portal/en/publications/7fb644c7-5846-430e-84e9-3cd9abf3991dTest

الإتاحة: https://pure.au.dk/portal/en/publications/7fb644c7-5846-430e-84e9-3cd9abf3991dTest
https://www.cell.com/biophysj/pdf/S0006-3495Test(18)33851-7.pdf

المؤلفون: Thøgersen, Lucy Kate Ladefoged, Schiøtt, Birgit, Kristensen, Anders Skov, Munro, Lachlan Jake

المصدر: Thøgersen, L K L, Schiøtt, B, Kristensen, A S & Munro, L J 2019, ' Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage-Clamp Fluorometry ', Molecular Pharmacology, vol. 96, no. 6, pp. 720-734 .

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pure_au_____::98ac2fd705da8c8723e6f12dd8ca89e9Test
https://pure.au.dk/portal/da/publications/conformational-changes-in-the-5ht3a-receptor-extracellular-domain-measured-by-voltageclamp-fluorometryTest(c9dd9d32-9cd1-4d0c-8683-ee7adada0243).html

المؤلفون: Andersen, Jacob, Sørensen, Lena, Strømgaard, Kristian, Kristensen, Anders Skov

المصدر: Andersen , J , Sørensen , L , Strømgaard , K & Kristensen , A S 2010 , ' Antidepressive lægemidler : nu i 3D ' , Lægemiddelforskning , bind 2010 , s. 25-27 .

مصطلحات موضوعية: /dk/atira/pure/core/keywords/TheFacultyOfPharmaceuticalSciences, Det tidligere Farmaceutiske Fakultet

وصف الملف: application/pdf

الإتاحة: https://curis.ku.dk/portal/da/publications/antidepressive-laegemidlerTest(3ae6a6c2-1e37-4a4c-817b-1bb7775f5514).html
https://curis.ku.dk/ws/files/32148741/Antidepressiva_3D.pdfTest

المؤلفون: Strømgaard, Kristian, Jensen, Mette Stougård, Kristensen, Anders Skov

المصدر: Strømgaard , K , Jensen , M S & Kristensen , A S 2009 , ' Skræddersyede proteiner : uden naturens begrænsninger ' , Lægemiddelforskning , s. 10-12 .

مصطلحات موضوعية: /dk/atira/pure/core/keywords/TheFacultyOfPharmaceuticalSciences, Det tidligere Farmaceutiske Fakultet

وصف الملف: application/pdf

الإتاحة: https://curis.ku.dk/portal/da/publications/skraeddersyede-proteinerTest(797069c0-f9e9-11de-825d-000ea68e967b).html
https://curis.ku.dk/ws/files/16784903/Skraeddersyede_proteiner.pdfTest