المؤلفون: Lidumniece, Elina, Withers-Martinez, Chrislaine, Hackett, Fiona, Collins, Christine R., Perrin, Abigail J., Koussis, Konstantinos, Bisson, Claudine, Blackman, Michael J., Jirgensons, Aigars

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2021 May . 118(20), 1-9.

الوصول الحر: https://www.jstor.org/stable/27040411Test

المؤلفون: Ramaprasad, Abhinay, Burda, Paul-Christian, Koussis, Konstantinos, Thomas, James A, Pietsch, Emma, Calvani, Enrica, Howell, Steven A, MacRae, James I, Snijders, Ambrosius P, Gilberger, Tim-Wolf, Blackman, Michael J

المساهمون: Kafsack, Bjorn FC

وصف الملف: text

العلاقة: https://researchonline.lshtm.ac.uk/id/eprint/4670733/1/Ramaprasad-etal-2023-A-malaria-parasite-phospholipase-facilitates-efficient-asexual-blood-stage-egress.pdfTest; Ramaprasad, Abhinay; Burda, Paul-Christian; Koussis, Konstantinos; Thomas, James A ; Pietsch, Emma; Calvani, Enrica; Howell, Steven A; MacRae, James I; Snijders, Ambrosius P; Gilberger, Tim-Wolf; +1 more. Blackman, Michael J ; (2023) A malaria parasite phospholipase facilitates efficient asexual blood stage egress. PLoS pathogens, 19 (6). e1011449-. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1011449Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1011449Test
https://researchonline.lshtm.ac.uk/id/eprint/4670733Test/
https://researchonline.lshtm.ac.uk/id/eprint/4670733/1/Ramaprasad-etal-2023-A-malaria-parasite-phospholipase-facilitates-efficient-asexual-blood-stage-egress.pdfTest

المؤلفون: Koussis, Konstantinos¹ (AUTHOR) konstantinos.kousis@lshtm.ac.uk, Haase, Silvia² (AUTHOR), Withers-Martinez, Chrislaine¹ (AUTHOR), Flynn, Helen R.³ (AUTHOR), Kunzelmann, Simone⁴ (AUTHOR), Christodoulou, Evangelos⁴ (AUTHOR), Ibrahim, Fairouz³ (AUTHOR), Skehel, Mark³ (AUTHOR), Baker, David A.⁵ (AUTHOR), Blackman, Michael J.^1,5 (AUTHOR) konstantinos.kousis@lshtm.ac.uk

المصدر: PLoS Pathogens. 6/27/2024, Vol. 20 Issue 6, p1-34. 34p.

مصطلحات موضوعية: *PLASMODIUM, *CGMP-dependent protein kinase, *PHOSPHORYLATION, *PARASITE life cycles, *ERYTHROCYTES, *SERINE/THREONINE kinases, *MALARIA prevention

المؤلفون: Balestra, Aurélia, Koussis, Konstantinos, Klages Jemelin, Natacha, Howell, Steven A., Flynn, Helen R., Bantscheff, Marcus, Pasquarello Mosimann, Carla, Perrin, Abigail J., Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castaño, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P., Baker, David A., Blackman, Michael J., Brochet, Mathieu

المصدر: ISSN: 2375-2548 ; Science Advances, vol. 7, no. 13 (2021) eabe5396.

مصطلحات موضوعية: info:eu-repo/classification/ddc/616, Plasmodium, Malaria, Kinase, Messager secondaire, CGMP, Calcium

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33762339; info:eu-repo/semantics/dataset/url/http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD020210Test; info:eu-repo/semantics/dataset/url/http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD020189Test; info:eu-repo/semantics/dataset/url/http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD020447Test; https://archive-ouverte.unige.ch/unige:150847Test; unige:150847

الإتاحة: https://doi.org/10.1126/sciadv.abe5396Test
https://archive-ouverte.unige.ch/unige:150847Test

المؤلفون: Tan, Michele SY, Koussis, Konstantinos, Withers-Martinez, Chrislaine, Howell, Steven A, Thomas, James A, Hackett, Fiona, Knuepfer, Ellen, Shen, Min, Hall, Matthew D, Snijders, Ambrosius P, Blackman, Michael J

وصف الملف: text

العلاقة: https://researchonline.lshtm.ac.uk/id/eprint/4661721/1/Autocatalytic%20activation%20of%20a%20malarial%20egress%20protease%20is%20druggable%20and%20requires%20a%20protein%20cofactor.pdfTest; Tan, Michele SY; Koussis, Konstantinos; Withers-Martinez, Chrislaine; Howell, Steven A; Thomas, James A ; Hackett, Fiona; Knuepfer, Ellen; Shen, Min; Hall, Matthew D; Snijders, Ambrosius P; +1 more. Blackman, Michael J ; (2021) Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor. The EMBO journal, 40 (11). e107226. ISSN 0261-4189 DOI: https://doi.org/10.15252/embj.2020107226Test

الإتاحة: https://doi.org/10.15252/embj.2020107226Test
https://researchonline.lshtm.ac.uk/id/eprint/4661721Test/
https://researchonline.lshtm.ac.uk/id/eprint/4661721/1/Autocatalytic%20activation%20of%20a%20malarial%20egress%20protease%20is%20druggable%20and%20requires%20a%20protein%20cofactor.pdfTest

المؤلفون: Balestra, Aurélia C, Koussis, Konstantinos, Klages, Natacha, Howell, Steven A, Flynn, Helen R, Bantscheff, Marcus, Pasquarello, Carla, Perrin, Abigail J, Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castaño, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P, Baker, David A, Blackman, Michael J, Brochet, Mathieu

وصف الملف: text

العلاقة: https://researchonline.lshtm.ac.uk/id/eprint/4661049/10/Balestra_etal_2021_Casup2plus-signals-critical-for-egress.pdfTest; Balestra, Aurélia C; Koussis, Konstantinos; Klages, Natacha; Howell, Steven A; Flynn, Helen R; Bantscheff, Marcus; Pasquarello, Carla; Perrin, Abigail J; Brusini, Lorenzo; Arboit, Patrizia; +9 more. Sanz, Olalla; Castaño, Laura Peces-Barba; Withers-Martinez, Chrislaine; Hainard, Alexandre; Ghidelli-Disse, Sonja; Snijders, Ambrosius P; Baker, David A ; Blackman, Michael J ; Brochet, Mathieu; (2021) Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG. Science advances, 7 (13). eabe5396-. ISSN 2375-2548 DOI: https://doi.org/10.1126/sciadv.abe5396Test

الإتاحة: https://doi.org/10.1126/sciadv.abe5396Test
https://researchonline.lshtm.ac.uk/id/eprint/4661049Test/
https://researchonline.lshtm.ac.uk/id/eprint/4661049/10/Balestra_etal_2021_Casup2plus-signals-critical-for-egress.pdfTest

المؤلفون: Tan, Michele S Y, Koussis, Konstantinos, Withers‐Martinez, Chrislaine, Howell, Steven A, Thomas, James A, Hackett, Fiona, Knuepfer, Ellen, Shen, Min, Hall, Matthew D, Snijders, Ambrosius P, Blackman, Michael J

المساهمون: Cancer Research UK, Medical Research Council, National Center for Advancing Translational Sciences

المصدر: The EMBO Journal ; volume 40, issue 11 ; ISSN 0261-4189 1460-2075

مصطلحات موضوعية: General Immunology and Microbiology, General Biochemistry, Genetics and Molecular Biology, Molecular Biology, General Neuroscience

الإتاحة: https://doi.org/10.15252/embj.2020107226Test

المؤلفون: Balestra, Aurélia C., Koussis, Konstantinos, Klages, Natacha, Howell, Steven A., Flynn, Helen R., Bantscheff, Marcus, Pasquarello, Carla, Perrin, Abigail J., Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castaño, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P., Baker, David A., Blackman, Michael J., Brochet, Mathieu

المساهمون: Novartis Foundation, Wellcome, Medical Research Council, Swiss National Science Foundation, Fondation privée des Hôpitaux Universitaires de Genève

المصدر: Science Advances ; volume 7, issue 13 ; ISSN 2375-2548

الإتاحة: https://doi.org/10.1126/sciadv.abe5396Test

المؤلفون: Koussis, Konstantinos, Withers-Martinez, Chrislaine, Baker, David A, Blackman, Michael J

وصف الملف: text

العلاقة: https://researchonline.lshtm.ac.uk/id/eprint/4657323/1/Simultaneous%20multiple%20allelic%20replacement%20in%20the%20malaria%20parasite%20enables%20dissection%20of%20PKG%20function.pdfTest; Koussis, Konstantinos; Withers-Martinez, Chrislaine; Baker, David A ; Blackman, Michael J ; (2020) Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function. LIFE SCIENCE ALLIANCE, 3 (4). e201900626-e201900626. ISSN 2575-1077 DOI: https://doi.org/10.26508/lsa.201900626Test

الإتاحة: https://doi.org/10.26508/lsa.201900626Test
https://researchonline.lshtm.ac.uk/id/eprint/4657323Test/
https://researchonline.lshtm.ac.uk/id/eprint/4657323/1/Simultaneous%20multiple%20allelic%20replacement%20in%20the%20malaria%20parasite%20enables%20dissection%20of%20PKG%20function.pdfTest

المؤلفون: Tarr, Sarah J, Withers-Martinez, Chrislaine, Flynn, Helen R, Snijders, Ambrosius P, Masino, Laura, Koussis, Konstantinos, Conway, David J, Blackman, Michael J

وصف الملف: text

العلاقة: https://researchonline.lshtm.ac.uk/id/eprint/4655984/11/Tarr-etal-2020_A_malaria_parasite_subtilisin_propeptide.pdfTest; Tarr, Sarah J; Withers-Martinez, Chrislaine; Flynn, Helen R; Snijders, Ambrosius P; Masino, Laura; Koussis, Konstantinos; Conway, David J ; Blackman, Michael J ; (2020) A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1. The Biochemical journal, 477 (2). pp. 525-540. ISSN 0264-6021 DOI: https://doi.org/10.1042/BCJ20190918Test

الإتاحة: https://doi.org/10.1042/BCJ20190918Test
https://researchonline.lshtm.ac.uk/id/eprint/4655984Test/
https://researchonline.lshtm.ac.uk/id/eprint/4655984/11/Tarr-etal-2020_A_malaria_parasite_subtilisin_propeptide.pdfTest