المؤلفون: Khanna, Ankita, Lotfi, Pouya, Chavan, Anita J., Montaño, Nieves M., Bolourani, Parvin, Weeks, Gerald, Shen, Zhouxin, Briggs, Steven P., Pots, Henderikus, Van Haastert, Peter J. M., Kortholt, Arjan, Charest, Pascale G.

مرشدي الرسالة: Univ Arizona, Dept Chem & Biochem

مصطلحات موضوعية: CONTROLS CELL-ADHESION, DICTYOSTELIUM-DISCOIDEUM, SIGNAL RELAY, MACROPHAGES PROMOTE, MEDIATED ACTIVATION, ACTIN CYTOSKELETON, PARACRINE LOOP, G-PROTEINS, CHEMOTAXIS, MIGRATION

العلاقة: http://www.nature.com/articles/srep25823Test

الإتاحة: http://hdl.handle.net/10150/614747Test
http://arizona.openrepository.com/arizona/handle/10150/614747Test

المؤلفون: Sabogal-Guáqueta, Angélica María, Marmolejo-Garza, Alejandro, Trombetta-Lima, Marina, Oun, Asmaa, Hunneman, Jasmijn, Chen, Tingting, Koistinaho, Jari, Lehtonen, Sarka, Kortholt, Arjan, Wolters, Justina C., Bakker, Barbara M., Eggen, Bart J.L., Boddeke, Erik, Dolga, Amalia

المساهمون: Helsinki Institute of Life Science HiLIFE, Neuroscience Center

مصطلحات موضوعية: General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: A.M.D. is the recipient of a Rosalind Franklin Fellowship co-funded by the European Union and the University of Groningen. A.M.D. and A.K. are recipients of a Parkinson Fonds grant. A.M.G. is financially supported by the GSMS. We thank for kind technical assistance Renzo Mancuso (VIB-UAntwerp Center for Molecular Neurology, Belgium), Nicola Fattorelli and Anna Martinez-Muriana (KU Leuven, Leuven, Belgium).; Sabogal-Guáqueta , A M , Marmolejo-Garza , A , Trombetta-Lima , M , Oun , A , Hunneman , J , Chen , T , Koistinaho , J , Lehtonen , S , Kortholt , A , Wolters , J C , Bakker , B M , Eggen , B J L , Boddeke , E & Dolga , A 2023 , ' Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction ' , Nature Communications , vol. 14 , no. 1 , 6454 . https://doi.org/10.1038/s41467-023-42096-7Test; ORCID: /0000-0001-6559-1153/work/150718875; http://hdl.handle.net/10138/569611Test; 0e23e28a-3ff2-4433-85a3-d0862a3f4260; 85174292601; 001117712600023

الإتاحة: http://hdl.handle.net/10138/569611Test

المؤلفون: Iannotta, Lucia, Emanuele, Marco, Favetta, Giulia, Tombesi, Giulia, Vandewynckel, Laurine, Lara Ordóñez, Antonio, Jesús, Saliou, Jean-Michel, Drouyer, Matthieu, Sibran, William, Civiero, Laura, Nichols, R. Jeremy, Athanasopoulos, Panagiotis, S, Kortholt, Arjan, Chartier-Harlin, Marie-Christine, Greggio, Elisa, Taymans, Jean-Marc

المساهمون: Lille Neurosciences & Cognition - U 1172 (LilNCog), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)

المصدر: ISSN: 1662-5099 ; Frontiers in Molecular Neuroscience ; https://hal.science/hal-04418786Test ; Frontiers in Molecular Neuroscience, 2023, 16, ⟨10.3389/fnmol.2023.1269387⟩.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

العلاقة: hal-04418786; https://hal.science/hal-04418786Test; https://hal.science/hal-04418786/documentTest; https://hal.science/hal-04418786/file/fnmol-16-1269387.pdfTest

الإتاحة: https://doi.org/10.3389/fnmol.2023.1269387Test
https://hal.science/hal-04418786Test
https://hal.science/hal-04418786/documentTest
https://hal.science/hal-04418786/file/fnmol-16-1269387.pdfTest

المؤلفون: Sabogal-Guáqueta, Angélica María, Marmolejo-Garza, Alejandro, Trombetta-Lima, Marina, Oun, Asmaa, Hunneman, Jasmijn, Chen, Tingting, Koistinaho, Jari, Lehtonen, Sarka, Kortholt, Arjan, Wolters, Justina C, Bakker, Barbara M, Eggen, Bart J L, Boddeke, Erik, Dolga, Amalia

المصدر: Sabogal-Guáqueta , A M , Marmolejo-Garza , A , Trombetta-Lima , M , Oun , A , Hunneman , J , Chen , T , Koistinaho , J , Lehtonen , S , Kortholt , A , Wolters , J C , Bakker , B M , Eggen , B J L , Boddeke , E & Dolga , A 2023 , ' Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction ' , Nature Communications , vol. 14 , no. 1 , 6454 . https://doi.org/10.1038/s41467-023-42096-7Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/eee8923f-f2e0-4897-b1bc-4a1bdf27f830Test

الإتاحة: https://doi.org/10.1038/s41467-023-42096-7Test
https://hdl.handle.net/11370/eee8923f-f2e0-4897-b1bc-4a1bdf27f830Test
https://research.rug.nl/en/publications/eee8923f-f2e0-4897-b1bc-4a1bdf27f830Test
https://pure.rug.nl/ws/files/803513615/s41467-023-42096-7.pdfTest

المؤلفون: Pathak, Pragya, Alexander, Krista K, Helton, Leah G, Kentros, Michalis, LeClair, Timothy J, Zhang, Xiaojuan, Ho, Franz Y, Moore, Timothy T, Hall, Scotty, Guaitoli, Giambattista, Gloeckner, Christian Johannes, Kortholt, Arjan, Rideout, Hardy, Kennedy, Eileen J

المصدر: Pathak , P , Alexander , K K , Helton , L G , Kentros , M , LeClair , T J , Zhang , X , Ho , F Y , Moore , T T , Hall , S , Guaitoli , G , Gloeckner , C J , Kortholt , A , Rideout , H & Kennedy , E J 2023 , ' Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) Dimerization ' , ACS chemical neuroscience , vol. 14 , no. 11 , 00259 , pp. 1971-1980 . https://doi.org/10.1021/acschemneuro.3c00259Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test

الإتاحة: https://doi.org/10.1021/acschemneuro.3c00259Test
https://hdl.handle.net/11370/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test
https://research.rug.nl/en/publications/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test
https://pure.rug.nl/ws/files/689526179/acschemneuro.3c00259.pdfTest

المؤلفون: Zhang, Xiaojuan, Kortholt, Arjan

المصدر: Zhang , X & Kortholt , A 2023 , ' LRRK2 Structure-Based Activation Mechanism and Pathogenesis ' , Biomolecules , vol. 13 , no. 4 , 612 . https://doi.org/10.3390/biom13040612Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/3dffab0f-5feb-44b8-b27e-e4ee1798ec38Test

الإتاحة: https://doi.org/10.3390/biom13040612Test
https://hdl.handle.net/11370/3dffab0f-5feb-44b8-b27e-e4ee1798ec38Test
https://research.rug.nl/en/publications/3dffab0f-5feb-44b8-b27e-e4ee1798ec38Test
https://pure.rug.nl/ws/files/625563821/biomolecules_13_00612_v2.pdfTest
https://www.mdpi.com/2218-273X/13/4/612Test

المؤلفون: Oun, Asmaa, Hoeksema, Emmy, Soliman, Ahmed, Brouwer, Famke, García-Reyes, Fabiola, Pots, Henderikus, Trombetta-Lima, Marina, Kortholt, Arjan, Dolga, Amalia M

المصدر: Oun , A , Hoeksema , E , Soliman , A , Brouwer , F , García-Reyes , F , Pots , H , Trombetta-Lima , M , Kortholt , A & Dolga , A M 2023 , ' Characterization of Lipopolysaccharide Effects on LRRK2 Signaling in RAW Macrophages ' , International Journal of Molecular Sciences , vol. 24 , no. 2 , 1644 . https://doi.org/10.3390/ijms24021644Test

مصطلحات موضوعية: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics, Lipopolysaccharides/pharmacology, Reactive Oxygen Species, Signal Transduction, Macrophages/metabolism, Mutation

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/eb2afdd5-b9ca-44e7-b745-73aec74904ebTest

الإتاحة: https://doi.org/10.3390/ijms24021644Test
https://hdl.handle.net/11370/eb2afdd5-b9ca-44e7-b745-73aec74904ebTest
https://research.rug.nl/en/publications/eb2afdd5-b9ca-44e7-b745-73aec74904ebTest
https://pure.rug.nl/ws/files/565095629/ijms_24_01644_v2.pdfTest

المؤلفون: Singh, Ranjan K, Soliman, Ahmed, Guaitoli, Giambattista, Störmer, Eliza, von Zweydorf, Felix, Dal Maso, Thomas, Oun, Asmaa, Van Rillaer, Laura, Schmidt, Sven H, Chatterjee, Deep, David, Joshua A, Pardon, Els, Schwartz, Thomas U, Knapp, Stefan, Kennedy, Eileen J, Steyaert, Jan, Herberg, Friedrich W, Kortholt, Arjan, Gloeckner, Christian Johannes, Versées, Wim

المساهمون: Massachusetts Institute of Technology. Department of Biology

المصدر: PNAS

وصف الملف: application/pdf

العلاقة: Proceedings of the National Academy of Sciences of the United States of America; https://hdl.handle.net/1721.1/146979Test; Singh, Ranjan K, Soliman, Ahmed, Guaitoli, Giambattista, Störmer, Eliza, von Zweydorf, Felix et al. 2022. "Nanobodies as allosteric modulators of Parkinson’s disease–associated LRRK2." Proceedings of the National Academy of Sciences of the United States of America, 119 (9).

الإتاحة: https://hdl.handle.net/1721.1/146979Test

المؤلفون: Sabogal, Angelica, Marmolejo, Alejandro, Lima, Marina Trombetta, Oun, Asmaa, Chen, Tingting, Koistinaho, Jari, Lehtonen, Šarka, Kortholt, Arjan, Bakker, Barbara, Eggen, Bart, Boddeke, Erik, Dolga, Amalia

المصدر: IBRO Neuroscience Reports ; volume 15, page S254-S255 ; ISSN 2667-2421

مصطلحات موضوعية: General Neuroscience

الإتاحة: https://doi.org/10.1016/j.ibneur.2023.08.432Test
https://api.elsevier.com/content/article/PII:S2667242123004943?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2667242123004943?httpAccept=text/plainTest

المؤلفون: Marchand, Antoine, Sarchione, Alessia, Athanasopoulos, Panagiotis, Roy, Hélène Bauderlique-Le, Goveas, Liesel, Magnez, Romain, Drouyer, Matthieu, Emanuele, Marco, Ho, Franz, Liberelle, Maxime, Melnyk, Patricia, Lebègue, Nicolas, Thuru, Xavier, Nichols, R. Jeremy, Greggio, Elisa, Kortholt, Arjan, Galli, Thierry, Chartier-Harlin, Marie-Christine, Taymans, Jean-Marc

المساهمون: Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Lille Neurosciences & Cognition - U 1172 (LilNCog), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), University of Groningen Groningen, Plateformes Lilloises en Biologie et Santé - UAR 2014 - US 41 (PLBS), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 (CANTHER), Stanford University, Università degli Studi di Padova = University of Padua (Unipd), Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), GHU Paris Psychiatrie et Neurosciences, Centre Hospitalier Sainte Anne Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), ANR-16-CE16-0012,MeTDePaDi,Défauts de Traffic Membranaire dans la Maladie de Parkinson(2016), ANR-20-CE16-0008,Synapark,Evaluation de l'implication de la fonction transcriptionnelle de la parkine dans le contrôle de l'alpha-synucléïne in vitro, in vivo et dans le sang de patients atteints de la Maladie de Parkinson(2020)

المصدر: ISSN: 2073-4409 ; Cells ; https://inserm.hal.science/inserm-03625821Test ; Cells, 2022, 11 (6), pp.1018. ⟨10.3390/cells11061018⟩.

مصطلحات موضوعية: LRRK2, Parkinson’s disease, RABs, lysosome, phosphorylation, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35326469; inserm-03625821; https://inserm.hal.science/inserm-03625821Test; https://inserm.hal.science/inserm-03625821/documentTest; https://inserm.hal.science/inserm-03625821/file/cells-11-01018.pdfTest; PUBMED: 35326469; PUBMEDCENTRAL: PMC8946913

الإتاحة: https://doi.org/10.3390/cells11061018Test
https://inserm.hal.science/inserm-03625821Test
https://inserm.hal.science/inserm-03625821/documentTest
https://inserm.hal.science/inserm-03625821/file/cells-11-01018.pdfTest