المؤلفون: Heikkinen, Sami, Huber, Nadine, Katisko, Kasper, Kokkola, Tarja, Hartikainen, Paivi, Kruger, Johanna, Leinonen, Ville, Korhonen, Ville E., Herukka, Sanna-Kaisa, Remes, Anne M., Borroni, Barbara, Alberici, Antonella, Libri, Ilenia, Solje, Eino, Haapasalo, Annakaisa

المساهمون: Department of Neurosciences, Faculty of Medicine, Clinicum

مصطلحات موضوعية: Biomarker, C9orf72, Grn, Mapt, Tdp-43, cathepsin S, Diagnostics, Frontotemporal dementia, Proteinopathy, Tau, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: Heikkinen , S , Huber , N , Katisko , K , Kokkola , T , Hartikainen , P , Kruger , J , Leinonen , V , Korhonen , V E , Herukka , S-K , Remes , A M , Borroni , B , Alberici , A , Libri , I , Solje , E & Haapasalo , A 2023 , ' Serum Cathepsin S Levels Do Not Show Alterations in Different Clinical, Neuropathological, or Genetic Subtypes of Frontotemporal Dementia Patients nor in Comparison to Healthy Control Individuals ' , Journal of Alzheimer's Disease , vol. 93 , no. 2 , pp. 395-401 . https://doi.org/10.3233/JAD-221060Test; e49253ab-c09f-4fc6-b09e-d2df0016ab48; http://hdl.handle.net/10138/571125Test; 000989648900001

الإتاحة: http://hdl.handle.net/10138/571125Test

المؤلفون: Lehtola, Juha-Matti, Kärkkäinen, Virve, Andberg, Sami, Hannonen, Sanna, Rusanen, Minna, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Kaarniranta, Kai, Bednarik, Roman, Leinonen, Ville, Koivisto, Anne M.

المساهمون: Department of Psychology and Logopedics, University of Helsinki, Department of Neurosciences, Clinicum, Helsinki University Hospital Area, Neurologian yksikkö

مصطلحات موضوعية: 3112 Neurosciences, 3124 Neurology and psychiatry, 515 Psychology, Alzheimer's disease (AD), biomarker, eye tracking (ET), idiopathic normal pressure hydrocephalus (iNPH), King-Devick (KD), saccadic eye movements

وصف الملف: application/pdf

العلاقة: The authors thank all study participants, statistician Tuomas Selander and study nurses Ulla Vanhanen, Kati Mönttinen, Kristiina Holopainen, Tarja Lappalainen, and Marita Parviainen. The authors are grateful to the Juho and Lempi Pitkänen foundation, the Maire Taponen Foundation, Maud Kuistila Foundation, Finnish Cultural Foundation, Finnish Brain Foundation and Finnish Government Research Funding for financial support.; Lehtola , J-M , Kärkkäinen , V , Andberg , S , Hannonen , S , Rusanen , M , Saari , T , Korhonen , V , Hokkanen , L , Hallikainen , M , Hänninen , T , Kaarniranta , K , Bednarik , R , Leinonen , V & Koivisto , A M 2022 , ' Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons with Idiopathic Normal Pressure Hydrocephalus from Cognitively Unimpaired ' , Alzheimer Disease and Associated Disorders , vol. 36 , no. 4 , pp. 340-346 . https://doi.org/10.1097/WAD.0000000000000527Test; ORCID: /0000-0001-8342-9248/work/129615356; ORCID: /0000-0001-7721-3336/work/130606708; 85143088755; c4b61cbd-6a88-4c59-a3c0-3cd47a10da40; http://hdl.handle.net/10138/354870Test; 000923752200010

الإتاحة: http://hdl.handle.net/10138/354870Test

المؤلفون: Heikkinen, Sami, Huber, Nadine, Katisko, Kasper, Kokkola, Tarja, Hartikainen, Päivi, Krüger, Johanna, Leinonen, Ville, Korhonen, Ville E, Herukka, Sanna-Kaisa, Remes, Anne M, Borroni, Barbara, Alberici, Antonella, Libri, Ilenia, Solje, Eino, Haapasalo, Annakaisa

المساهمون: Kliininen lääketiede, A.I. Virtanen -instituutti

مصطلحات موضوعية: biomarker, cathepsin S, C9orf72, diagnostics, frontotemporal dementia, GRN, MAPT, proteinopathy, tau, TDP-43

وصف الملف: 395-401

العلاقة: Journal of Alzheimer's disease; https://doi.org/10.3233/JAD-221060Test; 93; https://erepo.uef.fi/handle/123456789/30066Test

الإتاحة: https://doi.org/10.3233/JAD-221060Test
https://erepo.uef.fi/handle/123456789/30066Test

المؤلفون: Hannonen, Sanna, Andberg, Sami, Kärkkäinen, Virve, Rusanen, Minna, Lehtola, Juha-Matti, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Leinonen, Ville, Kaarniranta, Kai, Bednarik, Roman, Koivisto, Anne M.

المساهمون: Department of Psychology and Logopedics, University of Helsinki, Department of Neurosciences, HUS Neurocenter, Neurologian yksikkö, Geriatrian yksikkö

مصطلحات موضوعية: Alzheimer's disease, biomarker, CERAD, eye tracking, King-Devick, mild cognitive impairment, saccadic eye movements, CERAD NEUROPSYCHOLOGICAL BATTERY, KING-DEVICK TEST, ASSOCIATION WORKGROUPS, DIAGNOSTIC GUIDELINES, NATIONAL INSTITUTE, RECOMMENDATIONS, DEMENTIA, ALLELE, 3112 Neurosciences, 3124 Neurology and psychiatry, 515 Psychology, Neuropsychology

وصف الملف: application/pdf

العلاقة: We are deeply grateful to all of the study participants. We also thank BEGAD research project study nurses Ulla Vanhanen, Kati Monttinen, and Kristiina Holopainen for recruiting the study participants. We thank biostatistician Tuomas Selander for help with the statistical analysis. This work was supported by Juho and Lempi Pitkanen Foundation.; Hannonen , S , Andberg , S , Kärkkäinen , V , Rusanen , M , Lehtola , J-M , Saari , T , Korhonen , V , Hokkanen , L , Hallikainen , M , Hänninen , T , Leinonen , V , Kaarniranta , K , Bednarik , R & Koivisto , A M 2022 , ' Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer's Disease ' , Journal of Alzheimer's Disease , vol. 88 , no. 2 , pp. 609-618 . https://doi.org/10.3233/JAD-215551Test; ORCID: /0000-0001-8342-9248/work/117173311; cf23b6b3-9995-43a9-a640-5ab028bd110c; http://hdl.handle.net/10138/346799Test; 000828034300020

الإتاحة: http://hdl.handle.net/10138/346799Test

المؤلفون: Katisko, Kasper, Huber, Nadine, Kokkola, Tarja, Hartikainen, Päivi, Krüger, Johanna, Heikkinen, Anna-Leena, Paananen, Veera, Leinonen, Ville, Korhonen, Ville E., Helisalmi, Seppo, Herukka, Sanna-Kaisa, Cantoni, Valentina, Gadola, Yasmine, Archetti, Silvana, Remes, Anne M., Haapasalo, Annakaisa, Borroni, Barbara, Solje, Eino

المساهمون: Suomen Lääketieteen Säätiö, Suomalais-Norjalainen Lääketieteen Säätiö, OLVI-Säätiö, Maire Taposen Säätiö, Suomen Kulttuurirahasto, Maud Kuistilan Muistosäätiö, Suomen Aivosäätiö, ALS tutkimuksen tuki ry, Sigrid Juséliuksen Säätiö, Academy of Finland, Kuopion Yliopistollinen Sairaala, Päivikki ja Sakari Sohlbergin Säätiö, Yrjö Jahnssonin Säätiö, Orionin Tutkimussäätiö, Instrumentariumin Tiedesäätiö

المصدر: Alzheimer's Research & Therapy ; volume 14, issue 1 ; ISSN 1758-9193

مصطلحات موضوعية: Cognitive Neuroscience, Neurology (clinical), Neurology

الإتاحة: https://doi.org/10.1186/s13195-022-01091-8Test

المؤلفون: Lehtola, Juha-Matti, Kärkkäinen, Virve, Andberg, Sami, Hannonen, Sanna, Rusanen, Minna, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Kaarniranta, Kai, Bednarik, Roman, Leinonen, Ville, Koivisto, Anne M.

المصدر: Alzheimer Disease & Associated Disorders ; volume 36, issue 4, page 340-346 ; ISSN 0893-0341

الإتاحة: https://doi.org/10.1097/wad.0000000000000527Test

المؤلفون: Korhonen, Ville

مصطلحات موضوعية: fi=Rakennusmestarit|sv=Byggmästare|en=Construction Managers, vahingot ja vauriot, Rakennusalan työnjohdon tutkinto-ohjelma

العلاقة: http://www.theseus.fi/handle/10024/851588Test; URN:NBN:fi:amk-202404166612

الإتاحة: http://www.theseus.fi/handle/10024/851588Test

المؤلفون: Lukkarinen, Heikki, Tesseur, Ina, Pemberton, Darrel, Van der Ark, Peter, Timmers, Maarten, Slemmon, Randy, Janssens, Luc, Streffer, Johannes, Van Nueten, Luc, Bottelbergs, Astrid, Rauramaa, Tuomas, Koivisto, Anne M., Herukka, Sanna-Kaisa, Korhonen, Ville E., Junkkari, Antti, Hiltunen, Mikko, Engelborghs, Sebastiaan, Blennow, Kaj, Zetterberg, Henrik, Kolb, Hartmuth C., Leinonen, Ville

المساهمون: Department of Neurosciences, University of Helsinki, Geriatrian yksikkö, Helsinki University Hospital Area

مصطلحات موضوعية: A beta(42), biomarkers, idiopathic normal pressure hydrocephalus, neurofilament light, neurogranin, P-tau, T-tau, CORTICAL BRAIN BIOPSY, ALZHEIMERS-DISEASE, CSF BIOMARKERS, PROTEIN NEUROGRANIN, PHOSPHORYLATED TAU, SYNAPTIC PROTEIN, AMYLOID-BETA, DIAGNOSIS, INCREASE, Neurosciences, Neurology and psychiatry

وصف الملف: application/pdf

العلاقة: We would like to acknowledge Marita Parviainen, RN, for assistance and cognitive testing. The study was funded by Janssen R-D, a division of Janssen Pharmaceutica NV, Kuopio University Hospital VTR (#5252614) fund and Sigrid Juselius Foundation. HZ is a Wallenberg Scholar supported by grants from the Swedish Research Council (#2018-02532), the European Research Council (#681712), Swedish State Support for Clinical Research (#ALFGBG-720931), the Alzheimer Drug Discovery Foundation (ADDF), USA (#201809-2016862), and the UK Dementia Research Institute at UCL. KB is supported by the Swedish Research Council (#2017-00915), the Alz-heimer Drug Discovery Foundation (ADDF), USA (#RDAPB-201809-2016615), the Swedish Alzhei-mer Foundation (#AF-742881), Hj?rnfonden, Sweden (#FO2017-0243), the Swedish state under the agreement between the Swedish government and the County Councils, the ALF-agreement (#ALFGBG-715986), and European Union Joint Program for Neurodegenerative Disorders (JPND2019-466-236). We would like to acknowledge Marita Parviainen, RN, for assistance and cognitive testing. The study was funded by Janssen R&D, a division of Janssen Pharmaceutica NV, Kuopio University Hospital VTR (#5252614) fund and Sigrid Juselius Foundation. HZ is a Wallenberg Scholar supported by grants from the Swedish Research Council (#2018-02532), the European Research Council (#681712), Swedish State Support for Clinical Research (#ALFGBG-720931), the Alzheimer Drug Discovery Foundation (ADDF), USA (#201809-2016862), and the UK Dementia Research Institute at UCL. KB is supported by the Swedish Research Council (#2017-00915), the Alzheimer Drug Discovery Foundation (ADDF), USA (#RDAPB-201809-2016615), the Swedish Alzheimer Foundation (#AF-742881), Hjärnfonden, Sweden (#FO2017-0243), the Swedish state under the agreement between the Swedish government and the County Councils, the ALF-agreement (#ALFGBG-715986), and European Union Joint Program for Neurodegenerative Disorders (JPND2019-466-236).; Lukkarinen , H , Tesseur , I , Pemberton , D , Van der Ark , P , Timmers , M , Slemmon , R , Janssens , L , Streffer , J , Van Nueten , L , Bottelbergs , A , Rauramaa , T , Koivisto , A M , Herukka , S-K , Korhonen , V E , Junkkari , A , Hiltunen , M , Engelborghs , S , Blennow , K , Zetterberg , H , Kolb , H C & Leinonen , V 2021 , ' Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus ' , Journal of Alzheimer's Disease , vol. 80 , no. 4 , pp. 1629-1642 . https://doi.org/10.3233/JAD-201361Test; http://hdl.handle.net/10138/331743Test; b44c09e8-f378-4b9d-b8d0-f55a3cdd882b; 000642444400027

الإتاحة: http://hdl.handle.net/10138/331743Test

المؤلفون: Leskelä, Stina, Hoffmann, Dorit, Rostalski, Hannah, Huber, Nadine, Wittrahm, Rebekka, Hartikainen, Päivi, Korhonen, Ville, Leinonen, Ville, Hiltunen, Mikko, Solje, Eino, Remes, Anne M., Haapasalo, Annakaisa

المساهمون: Academy of Finland, Yrjö Jahnssonin Säätiö, Päivikki ja Sakari Sohlbergin Säätiö, Sigrid Juséliuksen Säätiö, Orionin Tutkimussäätiö, H2020 Marie Skłodowska-Curie Actions, Instrumentariumin Tiedesäätiö, Suomen Aivosäätiö, Emil Aaltosen Säätiö, ALS-tutkimuksen tuki ry, Strategic Neuroscience Funding of the University of Eastern Finland

المصدر: Molecular Neurobiology ; volume 58, issue 11, page 5438-5458 ; ISSN 0893-7648 1559-1182

مصطلحات موضوعية: Neuroscience (miscellaneous), Cellular and Molecular Neuroscience, Neurology

الإتاحة: https://doi.org/10.1007/s12035-021-02475-xTest

المؤلفون: Räsänen, Joel, Huovinen, Joel, Korhonen, Ville E., Junkkari, Antti, Kastinen, Sami, Komulainen, Simo, Oinas, Minna, Avellan, Cecilia, Frantzen, Janek, Rinne, Jaakko, Ronkainen, Antti, Kauppinen, Mikko, Lönnrot, Kimmo, Perola, Markus, Koivisto, Anne M., Remes, Anne M., Soininen, Hilkka, Hiltunen, Mikko, Helisalmi, Seppo, Kurki, Mitja I., Jääskeläinen, Juha E., Leinonen, Ville

المصدر: Fluids and Barriers of the CNS 17(1) 57

مصطلحات موضوعية: Normal pressure hydrocephalus, Familial, Comorbidities, Diabetes, Depression, Genetics, SFMBT1

العلاقة: https://zenodo.org/record/4040018Test; https://doi.org/10.1186/s12987-020-00217-0Test; oai:zenodo.org:4040018

الإتاحة: https://doi.org/10.1186/s12987-020-00217-0Test
https://zenodo.org/record/4040018Test