المؤلفون: Kiper, Aytug K., Bedoya, Mauricio, Stalke1, Sarah, Marzian, Stefanie, Ramírez, David, Cruz, Alicia de la, Peraza, Diego A., Vera Zambrano, Alba, Márquez Montesinos, José C. E., Arévalo Ramos, Bárbara A., Rinné, Susanne, González Gallego, Teresa, Valenzuela, Carmen, Gonzalez, Wendy, Decher, Niels

المساهمون: UAM. Departamento de Bioquímica

مصطلحات موضوعية: bupivacaine, Kv1 channels, local anaesthetics, ropivacaine, side pockets, stereoselectivity, Medicina

وصف الملف: application/pdf

العلاقة: British Journal of Pharmacology; https://doi.org/10.1111/bph.15480Test; Gobierno de España. 2019AEP148; Gobierno de España. PIE201820E104; Gobierno de España. SAF2016-75021-R; Gobierno de España. PID2019-104366RB-C21; British Journal Of Pharmacology 178 (2021): 3034-3048; 0007-1188 (online); http://hdl.handle.net/10486/710243Test; 3034; 3048; 178

الإتاحة: https://doi.org/10.1111/bph.15480Test
http://hdl.handle.net/10486/710243Test

المؤلفون: Rinné, Susanne, Kiper, Aytug K., Jacob, Ralf, Ortiz-Bonnin, Beatriz, Schindler, Roland F.R., Fischer, Sabine, Komadowski, Marlene, deMartino, Emilia, K.-H. Schäfer, Martin, Cornelius, Tamina, Fabritz, Larissa, Helker, Christian S.M., Brand, Thomas, Decher, Niels

المصدر: iScience ; page 109696 ; ISSN 2589-0042

مصطلحات موضوعية: Multidisciplinary

الإتاحة: https://doi.org/10.1016/j.isci.2024.109696Test
https://api.elsevier.com/content/article/PII:S2589004224009180?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2589004224009180?httpAccept=text/plainTest

المؤلفون: Schreiber, Julian Alexander, Derksen, Anastasia, Goerges, Gunnar, Schütte, Sven, Sörgel, Jasmin, Kiper, Aytug K., Strutz-Seebohm, Nathalie, Ruck, Tobias, Meuth, Sven G., Decher, Niels, Seebohm, Guiscard

المصدر: Communications Biology ; volume 6, issue 1 ; ISSN 2399-3642

مصطلحات موضوعية: General Agricultural and Biological Sciences, General Biochemistry, Genetics and Molecular Biology, Medicine (miscellaneous)

الإتاحة: https://doi.org/10.1038/s42003-023-05114-4Test
https://www.nature.com/articles/s42003-023-05114-4.pdfTest
https://www.nature.com/articles/s42003-023-05114-4Test

المؤلفون: Neelsen, Lea C., Riel, Elena B., Rinné, Susanne, Jürs, Björn C., Kiper, Aytug K., Eymsh, Bisher, Bedoya, Mauricio, Langer, Jan, Decher, Niels, Baukrowitz, Thomas, Schewe, Marcus

المصدر: Biophysical Journal ; volume 122, issue 3, page 174a ; ISSN 0006-3495

مصطلحات موضوعية: Biophysics

الإتاحة: https://doi.org/10.1016/j.bpj.2022.11.1087Test
https://api.elsevier.com/content/article/PII:S0006349522020033?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0006349522020033?httpAccept=text/plainTest

المؤلفون: Kiper, Aytug K.¹, Wegner, Sven¹, Kadala, Aklesso², Rinné, Susanne³, Schütte, Sven³, Winter, Zoltán², Bertoune, Mirjam A. R.¹, Touska, Filip¹, Matschke, Veronika⁴, Wrobel, Eva⁵, Streit, Anne-Kathrin¹, Lang, Florian⁶, Schmidt, Constanze⁷, Schulze-Bahr, Eric⁸, Schäfer, Martin K.-H.¹, Voelkl, Jakob⁹, Seebohm, Guiscard^1,8, Zimmermann, Katharina², Decher, Niels³ decher@staff.uni-marburg.de

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 6/18/2024, Vol. 121 Issue 25, p1-10. 15p.

المؤلفون: Matschke, Lina A, Komadowski, Marlene A, Stöhr, Annette, Lee, Bolam, Henrich, Martin T, Griesbach, Markus, Rinné, Susanne, Geibl, Fanni F, Chiu, Wei-Hua, Koprich, James B, Brotchie, Jonathan M, Kiper, Aytug K, Dolga, Amalia M, Oertel, Wolfgang H, Decher, Niels

المصدر: Matschke , L A , Komadowski , M A , Stöhr , A , Lee , B , Henrich , M T , Griesbach , M , Rinné , S , Geibl , F F , Chiu , W-H , Koprich , J B , Brotchie , J M , Kiper , A K , Dolga , A M , Oertel , W H & Decher , N 2022 , ' Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's disease ' , Scientific Reports , vol. 12 , no. ....

مصطلحات موضوعية: Animals, Cells, Cultured, Disease Models, Animal, Locus Coeruleus/physiology, Male, Mice, Inbred C57BL, Neurons/physiology, Norepinephrine/physiology, Parkinson Disease/physiopathology, Pars Compacta/physiology, Prodromal Symptoms, Rotenone, Small-Conductance Calcium-Activated Potassium Channels/physiology, alpha-Synuclein/metabolism

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/accf0a88-8dac-45f9-b7e3-32cfe4492f92Test

الإتاحة: https://doi.org/10.1038/s41598-022-06832-1Test
https://hdl.handle.net/11370/accf0a88-8dac-45f9-b7e3-32cfe4492f92Test
https://research.rug.nl/en/publications/accf0a88-8dac-45f9-b7e3-32cfe4492f92Test
https://pure.rug.nl/ws/files/211870135/s41598_022_06832_1.pdfTest

المؤلفون: Valdés Jiménez, Alejandro Mauricio, Jiménez González, Daniel, Kiper, Aytug K., Rinné, Susanne, Decher, Niels, González, Wendy, Reyes Parada, Miguel, Núñez Vivanco, Gabriel

المساهمون: Universitat Politècnica de Catalunya. Doctorat en Arquitectura de Computadors, Universitat Politècnica de Catalunya. Departament d'Arquitectura de Computadors, Barcelona Supercomputing Center, Universitat Politècnica de Catalunya. CAP - Grup de Computació d'Altes Prestacions

مصطلحات موضوعية: Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica, Àrees temàtiques de la UPC::Informàtica::Infografia, Three dimensional imaging in medicine, Polypharmacology, Binding site similarity, Cardiac ion channels, Tafluprost, Binding site comparisons, Imatgeria tridimensional en medicina

وصف الملف: application/pdf

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2022.855792/fullTest; info:eu-repo/grantAgreement/MINECO//TIN2015-65316-P/ES/COMPUTACION DE ALTAS PRESTACIONES VII/; info:eu-repo/grantAgreement/MINECO//SEV-2015-0493/ES/BARCELONA SUPERCOMPUTING CENTER - CENTRO. NACIONAL DE SUPERCOMPUTACION/; Valdés-Jiménez, A. [et al.]. A new strategy for multitarget drug discovery/repositioning through the identification of similar 3D amino acid patterns among proteins structures: The case of Tafluprost and its efects on cardiac ion channels. "Frontiers in pharmacology", 18 Març 2022, vol. 13, article 855792.; http://hdl.handle.net/2117/367538Test

الإتاحة: https://doi.org/10.3389/fphar.2022.855792Test
http://hdl.handle.net/2117/367538Test

المؤلفون: Camargo-Ayala, Lorena, Bedoya, Mauricio, Dasí, Albert, Prüser, Merten, Prent-Peñaloza, Luis, Adasme-Carreño, Francisco, Kiper, Aytug, Rinné, Susanne, Camargo-Ayala, Paola Andrea, Peña-Martínez, Paula Andrea, Bueno-Orovio, Alfonso, Varela, Diego, Wiedmann, Felix, Márquez-Montesinos, José Carlos Estanislao, Schmidt, Constanze, Rodriguez, Blanca, Ravens, Ursula, Decher, Niels, Gutiérrez, Margarita, González, Wendy

الإتاحة: https://doi.org/10.26434/chemrxiv-2024-v70ljTest
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/664dfba521291e5d1df8a817/original/polypharmacological-modulation-of-atrial-fibrillation-rational-design-synthesis-and-evaluation-of-novel-compounds-targeting-na-v1-5-kv1-5-and-k2p-channels.pdfTest

المؤلفون: Matschke, Lina, Komadowski, Marlene, Stöhr, Annette, Lee, Bolam, Henrich, Martin, Griesbach, Markus, Rinné, Susanne, Geibl, Fanni, Chiu, Wei-Hua, Koprich, James, Brotchie, Jonathan, Kiper, Aytug, Dolga, Amalia, Oertel, Wolfgang, Decher, Niels

الإتاحة: https://doi.org/10.22541/au.170668460.08395343/v1Test

المؤلفون: Kiper, Aytug K., Bedoya, Mauricio, Stalke, Sarah, Marzian, Stefanie, Ramírez, David, de la Cruz, Alicia, Peraza, Diego A., Vera‐Zambrano, Alba, Márquez Montesinos, José C. E., Arévalo Ramos, Bárbara A., Rinné, Susanne, Gonzalez, Teresa, Valenzuela, Carmen, Gonzalez, Wendy, Decher, Niels

وصف الملف: application/pdf

العلاقة: https://doi.org/10.1111/bph.15480Test; Br J Pharmacol . 2021 Aug;178(15):3034-3048. doi:10.1111/bph.15480. Epub 2021 May 14.; https://uvadoc.uva.es/handle/10324/66030Test; 3034; 15; 3048; British Journal of Pharmacology; 178

الإتاحة: https://doi.org/10.1111/bph.15480Test
https://uvadoc.uva.es/handle/10324/66030Test