المؤلفون: Khalfallah, Yousra

مرشدي الرسالة: Vande Velde, Christine

مصطلحات موضوعية: TDP-43, Sclérose Latérale Amyotrophique, Démence Fronto-temporale, Réponse au stress, Granules de Stress, Moelle épinière, Neurones moteurs et corticaux, Astrocytes, G3BP1, ARNm, Vieillissement, Amyotrophic Lateral Sclerosis, Fronto Temporal Dementia, Stress response, Stress granules, Spinal cord, Motor and cortical neurons, mRNA, Aging, Biology - Neuroscience / Biologie - Neurologie (UMI : 0317)

الإتاحة: http://hdl.handle.net/1866/21800Test

المؤلفون: Sidibé, Hadjara, Khalfallah, Yousra, Xiao, Shangxi, Gómez, Nicolás B, Fakim, Hana, Tank, Elizabeth M H, Di Tomasso, Geneviève, Bareke, Eric, Aulas, Anaïs, McKeever, Paul M, Melamed, Ze’ev, Destroimaisons, Laurie, Deshaies, Jade-Emmanuelle, Zinman, Lorne, Parker, J Alex, Legault, Pascale, Tétreault, Martine, Barmada, Sami J, Robertson, Janice, Vande Velde, Christine

المساهمون: ALS Canada, Brain Canada Hudson Translational Team, Muscular Dystrophy Association, James Hunter ALS Initiative, ALS Association Milton Safenowitz Postdoctoral Fellowship, National Institutes of Health, National Institute for Aging, FRQS Doctoral Studentship, FRQS Research Scholars

المصدر: Brain ; volume 144, issue 11, page 3461-3476 ; ISSN 0006-8950 1460-2156

الإتاحة: https://doi.org/10.1093/brain/awab217Test
https://academic.oup.com/brain/article-pdf/144/11/3461/41794604/awab217.pdfTest

المؤلفون: Miller, Timothy M, Cudkowicz, Merit E, Andrews, Jinsy A, Hesters, Adele, Kermorvant, Hugo, Lacomblez, Lucette, Forestier, Nadine Le, Lenglet, Thimotée, Retail, Maryvonne, Ruiz Del Mar Amador, Maria, Salachas, François, Shotar, Eimad, Sourour, Nader, Babu, Suma, Dorst, Johannes, Froehlich, Elke, Fromm, Andrea, Kandler, Katharina, Langer, Eva, Leichtle, Sarah, Ludolph, Albert, Mayer, Kristina, Michels, Sebastian, Raubold, Sabine, Benatar, Michael, Schuster, Joachim, Weiland, Ulrike, Wiesenfarth, Maximilian, Witzel, Simon, Calvo, Andrea, Canosa, Antonio, Casale, Federico, Chiò, Adriano, Fuda, Giuseppe, Grassano, Maurizio, McDermott, Christopher J, Marchese, Giulia, Moglia, Cristina, Palumbo, Francesca, Salamone, Paolina, Ajiki, Takahiro, Akasaka, Aya, Ando, Masahiro, Arata, Hitoshi, Asuka, Kitamura, Baba, Kosuke, Cochrane, Thos, Bekku, Goichi, Chiba, Tomoya, Date, Yugaku, Eriko, Takeuchi, Hashiguchi, Akihiro, Hatatori, Ritsuko, Hayano, Eri, Hayashi, Yuto, Higashi, Keiko, Higuchi, Eriko, Chary, Sowmya, Hiramatsu, Yu, Horikawa, Rui, Ikenaka, Kensuke, Ishiura, Hiroyuki, Ito, Daisuke, Kawai, Sachiko, Kikuchi, Junko, Kuzuyama, Haruko, Li, Xuehong, Matsumoto, Chika, Chew, Sheena, Matsuura, Eiji, Michizono, Kumiko, Mitsui, Jun, Mitsutake, Akihiko, Mochizuki, Hideki, Nagamatsu, Akemi, Nagano, Seiichi, Nakamura, Tomonori, Naruse, Hiroya, Ogasawara, Asuka, Zhu, Han, Okada, Kensuke, Okamoto, Yuji, Okuno, Tatsusada, Oyama, Satoshi, Ozono, Tatsuhiko, Sakiyama, Yusuke, Sakuishi, Kaori, Seki, Morinobu, Shibata, Shota, Shimizu, Mikito, Wu, Fan, Takahata, Katsunori, Takahito, Yoshizaki, Takashima, Hiroshi, Takeichi, Hiroko, Tashiro, Yuichi, Toda, Tatsushi, Tomizu, Yuki, Tomoya, Wadayama, Ujiakira, Nishiike, Yashita, Daiki, Nestorov, Ivan, Al-Chalabi, Ammar, Alix, James, Bangalore, Priyadarshini, Blackburn, Daniel, Chiwera, Theresa, Clegg, Rosie, Collins, Alexis, Cooper-Knock, Jonathan, Emery, Anna, Franklin, John, Genge, Angela, Graham, Danielle, Green, Louisa, Harvey, Callum, Hobson, Esther, Islam, Mahjabim, Jenkins, Thomas Michael, Kazoka, Mbombe, Kelly, Gillian, Korley, Mercy, Madarshahaian, Daniel, Mayl, Keith, Sun, Peng, McDermott, Christopher John, Radford, Alex, Shaw, Christopher, Shaw, Pamela J, Sidebottom, Joe, Smart, Lynne, Sreedharan, Jemeen, Stone, Ben, Tsironis, Theocharis, Tuddenham, Lee, McNeill, Manjit, Verber, Nick, Wollff, Helen, Young, Stacy, Zis, Panagiotis, Adamo, Ashley, Ahmed, Arubah, Ajroud-Driss, Senda, Alameda, Gustave, Arcila-Londono, Ximena, Fanning, Laura, Baird, Candy, Bazan, Tracy, Berry, James, Bordeau, Jane, Bradford, Wendy, Brook, Nyda, Brown, Lauren, Bucelli, Robert C, Ferguson, Toby A, Buckner, Katherine, Budler, Michael W, Burba, Lindita, Burke, Katherine, Calhoun, Ashley D, Campbell, Sarah, Carey, Judith, Caristo, Irys B, Carty, Simon, Chan, Emmanuel, Fradette, Stephanie, Chaudhry, Vinay, Chen, Ricky, Chow, Saephanh, Clawson, Lora L, Clemens, Mitchell, Cloninger, Suzann E, Coleman-Wood, Krista, Cooper, Thomas N, Cummings, Arlena, Daniels, Jacquelyn, VALOR, DeSaro, Pamela, DeWitt, Michelle, Dedi, Brixhilda, Dempsey, Debbie, Denny, Carol, Doherty, Jenna, Doherty, Leana, Donahue, Megan, Doyle, Michael, Duncan, Jessie, Group, OLE Working, Elman, Lauren, Eloge, Christine M, Echiti, Desirae R, Ferrey, Dominic, Fournier, Christina, Fukumura, Yuriko, Gallagher, Katherine, Garaycoa, Jessica, Garrett, Mark, Gibson, Richard L, Beullens, Lien, Gifford, Ryan, Glass, Jonathan D, Gogol, Danuta, Golden, Shea, Gonzalez, Alexa, Goodman, Ira, Goolsby, Christopher, Goslin, Kimberly, Goulbourne, Michael, Granit, Volkan, Claeys, Kristl, Grignon, Anne-Laure, GuhaRay, Adreeja, Guide, Debra, Gundogdu, Melek Betul, Gutierrez, Gil, Hastings, Debbie, Hayzen, Colleen, Herzog, Hilary, Holloway, Raegan, Jacobs, Gabriel, Claeys, Thomas, Jacobsen, Bill, James, Virginia, Jenkins, Liberty, Jockel-Balsarotti, Jennifer, Johnson, Linda Carol, Jose, Sunil, Joslin, Benjamin, Karanja, Elizabeth, Katz, Jonathan, Keener, Anthony, Couwelier, Goedele, Kittle, Gale, Klein, Sara, Kreple, Collin, Rebecca, Rebecca, Kuenzler, Kuenzler, Kusnir, Jorge, Labbe, Kristen, Lachica-Encinas, Nicolet, Ladha, Shafeeq, Leimer, Lesli, D'Hondt, Ann, Levy, Michael, Levy, Wendy, Li, Yingji, Likanje, Marie-France, Livigni, Rebecca, Locatelli, Eduardo, Luppino, Sarah, Malcolm, Amber, Maragakis, Nicholas, Marin, Horia, Debien, Elisa, Markowitz, Clyde, Markway, Jesse, McCaffrey, Alexandra, McCoy, Arita, McCoy Gross, Kelly, Mehta, Kush, Meyer, Robert, Milan, Jennifer, Miller, Timothy, Miller, Robert G, de Keersmaecker, Sebastiaan, Morales, Francisco, Mosmiller, Elizabeth, Mott, Donovan, Moulton, Kelsey, Murphy, Christine A, Negron, Tirso, Nelson, Cassandra, Newman, Daniel S, Nissinen, Janne Kristoffer, Norman, Andrew, Della Faille, Laetitia, Ohkubo, Takuya, Olney, Nicholas, Ortiz, Natasha, Oskarsson, Bjorn, Pace, Mitchell, Packard, Kathleen, Padgett, Denny, Paganoni, Sabrina, Paredes, Maria E, Parker, Elizabeth, Delmotte, Koen, Partlow, Ann, Pattee, Gary L, Paulett, Jany, Pelot, Antoinette, Pfeifer, Kyle M, Pijanowski, Olivia, Pioro, Erik, Polak, Meraida, Prakash, Ahalya, Previte, Rosemarie, Depoortere, Sofie, Pukenas, Bryan, Quinn, Colin, Ravits, John, Razavi, Ryan, Regan, Tyler, Riley, Kristen M, Roth, Heather, Sanders, Danica, Scalia, Jennifer, Schmidt, Emma, de Velder, Laura, Schwen, Edward, Shah, Jaimin, Shah, Stuti, Shefner, Jeremy, Sheldon, Danielle, Simmons, Karon, Singh, Navneet K, Singleton, Jessica, Smiley, Richard, Smith, William B, Dobbels, Laurens, Smith, Sean, Sotirchos, Elias, Sorenson, Eric, Staff, Nathan, Steele, Julie, Steijlen, Kara, Stirrat, Taylor, Stoica, George S, Strong, Stephanie, Sufit, Robert, Sobue, Gen, Gijs, Jeroen, Sultze, Jane, Swartz, Amy, Szymanski, April, Tay, Anna, Thakore, Nimish, Thiessen, Diana, Thotala, Sukrutha, Trudell, Randall G, Turcotte, Nicole, Turner, Michelle, Horckmans, Simon, Uchil, Alpa, Upadhyay, Vihar, Usman, Uzma, Vallis, Anne, Vaporean-Bussey, Danielle, Vladimirova, Valentine, Weber, Harli, Winbigler, Jennifer, Wojanowski, Heather, Wulf, Charlie, Lamaire, Nikita, Yasek, Julia, Yoo, Stephanie, Zivalic, Hannah, Cole, Alexandra, File, Greta, Foate, Jeremy, Mason, Deborah, Newton, Susan, Roberts, Stephen, Sellwood, Cory Dean, Liessens, Hannelore, Swan, James, Werno, Anja, Zhong, Cathy, Masrori, Pegah, Nysten, Celine, Schotte, Caroline, Serrien, Anouk, Swinnen, Bart, Tilkin, Petra, van Daele, Sien, Van Damme, Philip, Vynckier, Jan, Wouters, Anke, Abrahao, Agessandro, Angle, Mark, Badawy, Mohamed, Berube, Maxime, Bertone, Vanessa, Cooper, Sarah Marie, Dobrowolski, Peter, Fong, Helen, Hannouche, Matthew, Hartley, Denise, Hogan, Michael, Johnston, Wendy, Khalfallah, Yousra, Korngut, Lawrence, Kroetsch, Gina, Letourneau, Justin, Magnussen, Claire, Martinez, Jose, Massie, Rami, Mobach, Theodore, Mookshah, Jahan, Ozelsel, Timur, Parks, Andrea, Petrillo, Janet, Pfeffer, Gerald, Ludolph, Albert C, Pham, Shirley, Phung, Liane, Shiungsun, Rodney, Pi-Shan, Li, Santos, Denizart, Salmon, Kristiana, Saunders, Natalie, Sembinelli, Dylan, Tymkow, Kelsey, Wong, Berchman, Zinman, Lorne, Karlsborg, Merete, Pedersen Lomholt, Therese, Nilsson, Sigrid, Salvesen, Lisette, Skov, Pernille, Svenstrup, Kristen, Bruneteau, Gaelle, Calerencon, Frederic, Guimaraes Costa, Raquel

المصدر: The New England journal of medicine 387(12), 1099-1110 (2022). doi:10.1056/NEJMoa2204705

مصطلحات موضوعية: Adult, drug effects [Recovery of Function], Spinal, Oligonucleotides, blood [Neurofilament Proteins], administration & dosage [Oligonucleotides, Antisense], tofersen, Injections, blood [Amyotrophic Lateral Sclerosis], pharmacology [Oligonucleotides, Antisense], Superoxide Dismutase-1, Double-Blind Method, Neurofilament Proteins, Humans, ddc:610, Antisense, Injections, Spinal, Biomarkers, Recovery of Function, Amyotrophic Lateral Sclerosis, Oligonucleotides, Antisense, blood [Biomarkers], drug therapy [Amyotrophic Lateral Sclerosis], therapeutic use [Oligonucleotides, Antisense], SOD1 protein, human, General Medicine, genetics [Superoxide Dismutase-1], genetics [Amyotrophic Lateral Sclerosis], cerebrospinal fluid [Biomarkers], cerebrospinal fluid [Superoxide Dismutase-1], cerebrospinal fluid [Amyotrophic Lateral Sclerosis]

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47917f5cf517850ee212a77d7463f42Test
https://doi.org/10.1056/nejmoa2204705Test

المؤلفون: Semmler, Sabrina, Gagné, Myriam, Garg, Pranav, Pickles, Sarah R, Baudouin, Charlotte, Hamon-Keromen, Emeline, Destroismaisons, Laurie, Khalfallah, Yousra, Chaineau, Mathilde, Caron, Elise, Bayne, Andrew N, Trempe, Jean-François, Cashman, Neil R, Star, Alexandra T, Haqqani, Arsalan S, Durcan, Thomas M, Meiering, Elizabeth M, Robertson, Janice, Grandvaux, Nathalie, Plotkin, Steven S, McBride, Heidi M, Vande Velde, Christine

المساهمون: UCL - SSS/IONS - Institute of NeuroScience, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire

المصدر: The Journal of biological chemistry, Vol. 295, no.12, p. 3808-3825 (2020)

مصطلحات موضوعية: Amyotrophic Lateral Sclerosis, Animals, Antibodies, Cell Line, Disease Models, Animal, Mitochondria, Mutagenesis, Site-Directed, NF-kappa B, Protein Aggregates, Protein Folding, RNA Interference, RNA, Small Interfering, Rats, Transgenic, Superoxide Dismutase-1, TNF Receptor-Associated Factor 6, Ubiquitination, TNF receptor–associated factor (TRAF), amyotrophic lateral sclerosis (ALS) (Lou Gehrig disease), protein aggregation, protein misfolding, superoxide dismutase (SOD), ubiquitin

العلاقة: boreal:250021; http://hdl.handle.net/2078.1/250021Test; info:pmid/32029478; urn:ISSN:0021-9258; urn:EISSN:1083-351X

الإتاحة: https://doi.org/10.1074/jbc.RA119.011215Test
http://hdl.handle.net/2078.1/250021Test

المؤلفون: Khalfallah, Yousra, Kuta, Rachel, Grasmuck, Camille, Prat, Alexandre, Durham, Heather D., Vande Velde, Christine

المصدر: Scientific Reports ; volume 8, issue 1 ; ISSN 2045-2322

مصطلحات موضوعية: Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41598-018-25767-0Test
https://www.nature.com/articles/s41598-018-25767-0.pdfTest
https://www.nature.com/articles/s41598-018-25767-0Test

المؤلفون: Deshaies, Jade-Emmanuelle, Shkreta, Lulzim, Moszczynski, Alexander J, Sidibé, Hadjara, Semmler, Sabrina, Fouillen, Aurélien, Bennett, Estelle R., Bekenstein, Uriya, Destroismaisons, Laurie, Toutant, Johanne, Delmotte, Quentin, Volkening, Kathryn, Stabile, Stéphanie, Aulas, Anaïs, Khalfallah, Yousra, Soreq, Hermona, Nanci, Antonio, Strong, Michael J, Chabot, Benoit, Vande Velde, Christine

المساهمون: CIHR

المصدر: Brain ; volume 141, issue 5, page 1320-1333 ; ISSN 0006-8950 1460-2156

الإتاحة: https://doi.org/10.1093/brain/awy062Test
http://academic.oup.com/brain/article-pdf/141/5/1320/25083173/awy062.pdfTest

المؤلفون: Khalfallah, Yousra, Genge, Angela

المصدر: Journal of the Neurological Sciences ; volume 423, page 117359 ; ISSN 0022-510X

مصطلحات موضوعية: Neurology (clinical), Neurology

الإتاحة: https://doi.org/10.1016/j.jns.2021.117359Test
https://api.elsevier.com/content/article/PII:S0022510X21000526?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0022510X21000526?httpAccept=text/plainTest