المؤلفون: Johannes Meiser, Anne Schuster, Matthias Pietzke, Johan Vande Voorde, Dimitris Athineos, Kristell Oizel, Guillermo Burgos-Barragan, Niek Wit, Sandeep Dhayade, Jennifer P. Morton, Emmanuel Dornier, David Sumpton, Gillian M. Mackay, Karen Blyth, Ketan J. Patel, Simone P. Niclou, Alexei Vazquez

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/3791b6fce2b1446482c02c147ec6dfd2Test

المؤلفون: Tobias John, Nadia Saffoon, John Walsby-Tickle, Svenja S Hester, Felix A Dingler, Christopher L Millington, James SO McCullagh, Ketan J Patel, Richard J Hopkinson, Christopher J Schofield

مصطلحات موضوعية: Uncategorized, Uncategorised value

العلاقة: 2381/25041752.v1; https://figshare.com/articles/journal_contribution/Aldehyde-mediated_inhibition_of_asparagine_biosynthesis_has_implications_for_diabetes_and_alcoholism/25041752Test

الإتاحة: https://figshare.com/articles/journal_contribution/Aldehyde-mediated_inhibition_of_asparagine_biosynthesis_has_implications_for_diabetes_and_alcoholism/25041752Test

المؤلفون: Sally B. Morton (14312875), L. David Finger (14312878), Roxanne van der Sluijs (14312881), William D. Mulcrone (14312884), Michael Hodskinson (14312887), Christopher L. Millington (3072237), Christina Vanhinsbergh (14312890), Ketan J. Patel (14312893), Mark J. Dickman (1893028), Puck Knipscheer (14312896), Jane A. Grasby (2264884), David M. Williams (16225)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, yield upon incubation, stable reduced form, potentially lethal events, involved lengthy post, bone marrow failure, linked duplex displayed, prevent dna replication, 2 ′- deoxyinosine, reduced icl using, show using, duplex resulting, yielding approach, vivo <, room temperature, reaction forms, r <, proteins within, previous routes, opposite strands, n <

العلاقة: https://figshare.com/articles/journal_contribution/Efficient_Synthesis_of_DNA_Duplexes_Containing_Reduced_Acetaldehyde_Interstrand_Cross-Links/21799459Test

الإتاحة: https://doi.org/10.1021/jacs.2c10070.s001Test

المؤلفون: Felix A Dingler, Meng Wang, Anfeng Mu, Christopher L Millington, Nina Oberbeck, Sam Watcham, Lucas B Pontel, Ashley N Kamimae-Lanning, Frederic Langevin, Camille Nadler, Rebecca L Cordell, Paul S Monks, Rui Yu, Nicola K Wilson, Asuka Hira, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Masayuki Kobayashi, Toshinori Moriguchi, Tomoo Osumi, Motohiro Kato, Satoru Miyano, Etsuro Ito, Seiji Kojima, Hiromasa Yabe, Miharu Yabe, Keitaro Matsuo, Seishi Ogawa, Berthold Göttgens, Michael RG Hodskinson, Minoru Takata, Ketan J Patel

مصطلحات موضوعية: Uncategorized, DNA damage, ageing, bone marrow failure, cancer, formaldehyde, hematopoiesis, hematopoietic stem cells, immunodeficiency, mutagenesis, oncometabolite

العلاقة: 2381/13234163.v1; https://figshare.com/articles/journal_contribution/Two_Aldehyde_Clearance_Systems_Are_Essential_to_Prevent_Lethal_Formaldehyde_Accumulation_in_Mice_and_Humans_/13234163Test

الإتاحة: https://figshare.com/articles/journal_contribution/Two_Aldehyde_Clearance_Systems_Are_Essential_to_Prevent_Lethal_Formaldehyde_Accumulation_in_Mice_and_Humans_/13234163Test

المؤلفون: Sally B. Morton, L. David Finger, Roxanne van der Sluijs, William D. Mulcrone, Michael Hodskinson, Christopher L. Millington, Christina Vanhinsbergh, Ketan J. Patel, Mark J. Dickman, Puck Knipscheer, Jane A. Grasby, David M. Williams

المصدر: Journal of the American Chemical Society.

مصطلحات موضوعية: Colloid and Surface Chemistry, General Chemistry, Biochemistry, Catalysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1b46b5a757461d1e3eaa694eafae56Test
https://pubmed.ncbi.nlm.nih.gov/36584283Test

المؤلفون: Shabih Shakeel, Christopher J. Russo, Gianluca Degliesposti, Pablo Alcón, Eeson Rajendra, J.M. Skehel, Ketan J. Patel, Sarah L. Maslen, Carol V. Robinson, Chris H. Hill, Dror S. Chorev, Francis J. O’Reilly, Juri Rappsilber, Shaoda He, Sjors H.W. Scheres, Lori A. Passmore

المصدر: Shakeel, S, Rajendral, E, Alcón, P, O’Reilly, F J, Chorev, D S, Maslen, S, Degliesposti, G, Russo, C J, He, S, Hill, C H, Skehel, J M, Scheres, S H W, Patel, K J, Rappsilber, J, Robinson, C V & Passmore, L A 2019, ' Structure of the fanconi anaemia monoubiquitin ligase complex ', Nature, vol. 575, pp. 234-237 . https://doi.org/10.1038/s41586-019-1703-4Test
Nature

مصطلحات موضوعية: Models, Molecular, Protein subunit, Fanconi Anemia Complementation Group L Protein, medicine.disease_cause, Article, Mass Spectrometry, Ligases, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, FANCD2, Ring finger, medicine, Humans, Animals, FANCL, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA ligase, Mutation, Multidisciplinary, biology, Fanconi Anemia Complementation Group D2 Protein, Cryoelectron Microscopy, Ubiquitination, Fanconi Anemia Complementation Group Proteins, Ubiquitin ligase, Cell biology, FANCB, Protein Subunits, Fanconi Anemia, medicine.anatomical_structure, chemistry, Multiprotein Complexes, biology.protein, Protein Multimerization, Chickens, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bffaa0a6d75638ea3668a8eca98bf3Test
https://doi.org/10.1038/s41586-019-1703-4Test

المؤلفون: Olga V. Kochenova, Justin L. Sparks, Meng Wang, Lin Deng, Johannes C. Walter, Michael R. G. Hodskinson, Daniel R. Semlow, Ravindra Amunugama, Gheorghe Chistol, Claudia A. Mimoso, Emily Low, R. Alex Wu, Ketan J. Patel, Ashley N. Kamimae-Lanning

المصدر: Nature

مصطلحات موضوعية: DNA Replication, DNA Repair, DNA repair, Ubiquitin-Protein Ligases, Xenopus, macromolecular substances, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, hemic and lymphatic diseases, Animals, Humans, N-Glycosyl Hydrolases, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, Ubiquitin, Chemistry, technology, industry, and agriculture, DNA Helicases, Ubiquitination, DNA replication, Helicase, DNA, Minichromosome Maintenance Complex Component 7, GINS, Ubiquitin ligase, Cell biology, DNA glycosylase, biology.protein, Replisome, Female, 030217 neurology & neurosurgery, Protein Binding

وصف الملف: application/pdf; image/jpeg

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7999320f7690bda56182d186dfb54b8Test
https://doi.org/10.1038/s41586-019-1002-0Test

المؤلفون: Gillian M. Mackay, Niek Wit, Jacqueline Tait-Mulder, David Sumpton, Ketan J. Patel, Alexei Vazquez, Matthias Pietzke, Guillermo Burgos-Barragan

المساهمون: Sumpton, David [0000-0002-9004-4079], Vazquez, Alexei [0000-0003-2764-3244], Apollo - University of Cambridge Repository

المصدر: Communications Chemistry, Vol 3, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: 0301 basic medicine, 631/45, Formaldehyde, Aldehyde dehydrogenase, Biochemistry, lcsh:Chemistry, Isotopic labeling, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Materials Chemistry, Environmental Chemistry, 631/92/1643, Histidine, chemistry.chemical_classification, 34 Chemical Sciences, biology, article, General Chemistry, Glutathione, Amino acid, 030104 developmental biology, lcsh:QD1-999, chemistry, biology.protein, 64/60, Methanol, 030217 neurology & neurosurgery, Cysteine

وصف الملف: application/pdf; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e943349fe88a693787d28e05f9389df8Test
https://www.repository.cam.ac.uk/handle/1810/317845Test

المؤلفون: David M. Williams, Mohan Mahesh, Merlijn Witte, Ketan J. Patel, Puck Knipscheer, Koichi Sato, Jason W. Chin, Maya Petek, Koos Rooijers, Michael R. G. Hodskinson, Ashley N. Kamimae-Lanning, Jan Silhan, Jop Kind, Alice Bolner

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Nature
Nature, 579(7800), 603-608. Nature Publishing Group
Cell Res

مصطلحات موضوعية: DNA Replication, DNA Repair, DNA polymerase, DNA damage, Xenopus, Acetaldehyde, DNA-Directed DNA Polymerase, macromolecular substances, Xenopus Proteins, Article, 03 medical and health sciences, chemistry.chemical_compound, medicine, Animals, Point Mutation, Mutation frequency, 030304 developmental biology, Cisplatin, 0303 health sciences, Multidisciplinary, Ethanol, biology, Chemistry, 030302 biochemistry & molecular biology, technology, industry, and agriculture, DNA, biology.organism_classification, Nucleotidyltransferases, Research Highlight, Cell biology, Cross-Linking Reagents, Fanconi Anemia, Mutagenesis, biology.protein, REV1, DNA Damage, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f54122ce1c4a07e245de32eda5cc1bTest
https://europepmc.org/articles/PMC7116288Test/

المؤلفون: Juri Rappsilber, Pablo Alcón, Lori A. Passmore, Shabih Shakeel, Zhuo A. Chen, Ketan J. Patel

المصدر: Alcón, P, Shakeel, S, Chen, Z A, Rappsilber, J, Patel, K J & Passmore, L A 2020, ' FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair ', Nature Structural and Molecular Biology, vol. 27, no. 3, pp. 240-248 . https://doi.org/10.1038/s41594-020-0380-1Test
Nature structural & molecular biology

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA damage, DNA repair, DNA-binding protein, Article, law.invention, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ubiquitin, Structural Biology, law, hemic and lymphatic diseases, FANCD2, Monoubiquitination, Molecular Biology, 030304 developmental biology, 0303 health sciences, biology, nutritional and metabolic diseases, Cell biology, chemistry, Recombinant DNA, biology.protein, 030217 neurology & neurosurgery, DNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dee59bf22e62e4f4da816000c77deeTest
https://www.pure.ed.ac.uk/ws/files/157669496/PMID32066963_AAM_Rappsilber.pdfTest