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1دورية أكاديمية
المؤلفون: Xiaoyu Zhang (62901), Lena M. Luukkonen (10499083), Christie L. Eissler (10499086), Vincent M. Crowley (4419007), Yu Yamashita (1421008), Michael A. Schafroth (1771792), Shota Kikuchi (8968940), David S. Weinstein (2123176), Kent T. Symons (2252773), Brian E. Nordin (10499089), Joe L. Rodriguez (10499092), Thomas G. Wucherpfennig (10499095), Ludwig G. Bauer (10499098), Melissa M. Dix (1616689), Dean Stamos (1600186), Todd M. Kinsella (10499101), Gabriel M. Simon (131638), Kristen A. Baltgalvis (10499104), Benjamin F. Cravatt (93774)
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Electrophilic Proteolysis-Targeting., E 3-binding compounds, prostate cancer cells, Targeted Protein Degradation, ligand-induced protein degradation, E 3 ligase substrate adaptor, DCAF 11-directed electrophilic PROTACs, E 3 ligase, support ligand-induced protein degr., E 3 ligases, candidate electrophilic PROTACs, FBKP, electrophilic PROTACs act, DCAF 11
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المؤلفون: Jeffrey H. Hager, Nicholas D. Smith, Tadimeti S. Rao, Stewart A. Noble, Andrew K. Shiau, Jerry Muhammad, Robert L. Davis, James W. Malecha, Alan Saven, Brandon M. Wiley, Sara J. Dozier, Timothy Z. Hoffman, Elena L. Milkova, John V. Anzola, Yan Wang, Carol Trotter, Céline Bonnefous, David A. Jenkins, Joseph E. Payne, Paul L. Wash, Tami Annable, Phan-Manh Nguyen, Xin Guo, Kent T. Symons, Christian A. Hassig
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0239cd0b9e59719d73ad9a95a451c7a2Test
https://doi.org/10.1158/1535-7163.22485309Test -
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المؤلفون: Jeffrey H. Hager, Nicholas D. Smith, Tadimeti S. Rao, Stewart A. Noble, Andrew K. Shiau, Jerry Muhammad, Robert L. Davis, James W. Malecha, Alan Saven, Brandon M. Wiley, Sara J. Dozier, Timothy Z. Hoffman, Elena L. Milkova, John V. Anzola, Yan Wang, Carol Trotter, Céline Bonnefous, David A. Jenkins, Joseph E. Payne, Paul L. Wash, Tami Annable, Phan-Manh Nguyen, Xin Guo, Kent T. Symons, Christian A. Hassig
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad2d0b912497ade790e8191dc8a1a6aTest
https://doi.org/10.1158/1535-7163.22485300Test -
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المؤلفون: Jeffrey H. Hager, Nicholas D. Smith, Tadimeti S. Rao, Stewart A. Noble, Andrew K. Shiau, Jerry Muhammad, Robert L. Davis, James W. Malecha, Alan Saven, Brandon M. Wiley, Sara J. Dozier, Timothy Z. Hoffman, Elena L. Milkova, John V. Anzola, Yan Wang, Carol Trotter, Céline Bonnefous, David A. Jenkins, Joseph E. Payne, Paul L. Wash, Tami Annable, Phan-Manh Nguyen, Xin Guo, Kent T. Symons, Christian A. Hassig
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14bc54c95af4c3db718bbfdaab0ab55Test
https://doi.org/10.1158/1535-7163.22485303.v1Test -
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المؤلفون: Jeffrey H. Hager, Nicholas D. Smith, Tadimeti S. Rao, Stewart A. Noble, Andrew K. Shiau, Jerry Muhammad, Robert L. Davis, James W. Malecha, Alan Saven, Brandon M. Wiley, Sara J. Dozier, Timothy Z. Hoffman, Elena L. Milkova, John V. Anzola, Yan Wang, Carol Trotter, Céline Bonnefous, David A. Jenkins, Joseph E. Payne, Paul L. Wash, Tami Annable, Phan-Manh Nguyen, Xin Guo, Kent T. Symons, Christian A. Hassig
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1f183e54b1bbd2454f1a4fe5e3e9deTest
https://doi.org/10.1158/1535-7163.c.6531885.v1Test -
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المؤلفون: Kristen A. Baltgalvis, Vincent M. Crowley, Michael A. Schafroth, Brian E. Nordin, Benjamin F. Cravatt, Christie L Eissler, Joe L Rodriguez, Shota Kikuchi, Xiaoyu Zhang, Thomas G Wucherpfennig, Todd Kinsella, Kent T Symons, Melissa M. Dix, David S. Weinstein, Dean Stamos, Gabriel M. Simon, Yu Yamashita, Ludwig Bauer, Lena M Luukkonen
المصدر: J Am Chem Soc
مصطلحات موضوعية: Male, Proteasome Endopeptidase Complex, Proteolysis, Protein degradation, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Catalysis, Chimera (genetics), Colloid and Surface Chemistry, Cell Line, Tumor, medicine, Humans, Receptor, medicine.diagnostic_test, biology, Ubiquitin, Chemistry, Prostatic Neoplasms, Ubiquitin-Protein Ligase Complexes, General Chemistry, 0104 chemical sciences, Ubiquitin ligase, Cell biology, Androgen receptor, Receptors, Androgen, Cell culture, Cancer cell, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9801b3a3bafd3e374259ca9ad1a1524Test
https://doi.org/10.1021/jacs.1c00990Test -
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المؤلفون: Christie L Eissler, Todd Kinsella, Gabe Simon, Colin Walsh, Joseph Klebba, Joel Chick, Ali Tabatabaei, Lena M Luukkonen, Landon Whitby, Kent T Symons, Kristen A. Baltgalvis, Yuta Naro, Matthew P. Patricelli, Larry Burgess, Dean Stamos, Joon Chang, Shota Kikuchi, Jaclyn Brannon, Charles Chapman, Brian E. Nordin
المصدر: Cancer Research. 80:6411-6411
مصطلحات موضوعية: Cancer Research, biology, Chemistry, Computational biology, Protein degradation, Proteomics, Small molecule, Ubiquitin ligase, Oncology, Tissue expression, Covalent bond, biology.protein, Catalytic efficiency, Cullin
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0fd8700abc857dc43915d725ae6b6f54Test
https://doi.org/10.1158/1538-7445.am2020-6411Test -
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المؤلفون: Nahid Yazdani, Peter J. Rix, Sergio G. Duron, Celine Bonnefous, Xiaohong Chen, Kent T. Symons, Yan Zhang, Hui Zhang, Li Wang, Stewart A. Noble, Nicholas D. Smith, Christian A. Hassig, Andrew K. Shiau, Natasha Rozenkrants, Tadimeti S. Rao, Andrew K. Lindstrom, Marciano Sablad
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:1237-1241
مصطلحات موضوعية: Models, Molecular, Pyrimidine, medicine.drug_class, Clinical Biochemistry, Nitric Oxide Synthase Type II, Pharmaceutical Science, Inflammation, Quinolones, Pharmacology, Crystallography, X-Ray, Ligands, Biochemistry, Nitric oxide, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Overproduction, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, Organic Chemistry, Stereoisomerism, Quinolone, Nitric oxide synthase, Piperazine, Enzyme, chemistry, biology.protein, Molecular Medicine, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448d2dd16ce9736e877543f4bd122ddbTest
https://doi.org/10.1016/j.bmcl.2011.11.073Test -
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المؤلفون: Christian A. Hassig, Marciano Sablad, Li Wang, Phan M. Nguyen, Celine Bonnefous, Joseph E. Payne, Kent T. Symons, Nahid Yazdani, Stewart A. Noble, Tadimeti S. Rao, Andrew K. Shiau, Yan Zhang, Natasha Rozenkrants, Nicholas D. Smith, Peter J. Rix
المصدر: Journal of Medicinal Chemistry. 53:7739-7755
مصطلحات موضوعية: Gene isoform, Benzimidazole, Arginine, Administration, Oral, Nitric Oxide Synthase Type II, Pain, Nitric Oxide Synthase Type I, In Vitro Techniques, Pharmacology, Cell Line, Nitric oxide, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Humans, Pain Measurement, chemistry.chemical_classification, Analgesics, biology, Peripheral Nervous System Diseases, Drug Tolerance, Nitric oxide synthase, Nociception, Enzyme, chemistry, Biochemistry, Pyrazines, Rotarod Performance Test, Microsomes, Liver, biology.protein, Molecular Medicine, Protein Multimerization, Fluoroquinolones
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7572d389599529be2a393849f172fd2dTest
https://doi.org/10.1021/jm100828nTest -
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المؤلفون: Kent T. Symons, Li Wang, Christian A. Hassig, Joseph E. Payne, Yan Zhang, Steven Dorow, Andrew K. Shiau, Nicholas D. Smith, Celine Bonefous, Nahid Yazdani, Lena M. Staszewski, Peter J. Rix, Natasha Rozenkrants, Phan M. Nguyen, Marciano Sablad, John V. Anzola, Jerry Muhammad, Tadimeti S. Rao, Mark E. Massari, Stewart A. Noble
المصدر: The Journal of pharmacology and experimental therapeutics. 336(2)
مصطلحات موضوعية: Male, Pregabalin, Anti-Inflammatory Agents, Nitric Oxide Synthase Type II, Nitric Oxide Synthase Type I, Pharmacology, Motor Activity, Nitric oxide, chemistry.chemical_compound, Mice, In vivo, medicine, Potency, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Enzyme Inhibitors, Gastrointestinal Transit, Cells, Cultured, Analgesics, Mice, Inbred BALB C, Chemistry, Macaca mulatta, Mice, Inbred C57BL, Allodynia, Pyrazines, Hyperalgesia, Celecoxib, Morphine, Molecular Medicine, medicine.symptom, Protein Multimerization, medicine.drug, Fluoroquinolones
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7109a53b8717e0224eb4527fa6e628dTest
https://pubmed.ncbi.nlm.nih.gov/21036913Test