The Effects of Ventilatory Mode on Lung Aeration Assessed With Computer Tomography: A Randomized Controlled Study
| العنوان: | The Effects of Ventilatory Mode on Lung Aeration Assessed With Computer Tomography: A Randomized Controlled Study |
|---|---|
| المؤلفون: | Markku Hynynen, Katriina Pohjanen, Ville Pettilä, Antti Markkola, Tero Varpula, Päivi Valta, Juha Halavaara |
| المصدر: | Journal of Intensive Care Medicine. 24:122-130 |
| بيانات النشر: | SAGE Publications, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Adult, Male, Pulmonary Atelectasis, Time Factors, Randomization, medicine.medical_treatment, Acute Lung Injury, Hemodynamics, Lung injury, Critical Care and Intensive Care Medicine, Airway pressure release ventilation, 03 medical and health sciences, 0302 clinical medicine, Confidence Intervals, Humans, Medicine, 030212 general & internal medicine, Continuous positive airway pressure, Mechanical ventilation, Lung, Continuous Positive Airway Pressure, business.industry, Middle Aged, Respiration, Artificial, medicine.anatomical_structure, 030228 respiratory system, Anesthesia, Breathing, Female, Respiratory Insufficiency, Tomography, X-Ray Computed, business |
| الوصف: | Maintenance of spontaneous breathing superimposed on mechanical ventilation is suggested to improve gas exchange in patients with acute lung injury. The aim of this study was to evaluate the long-term effects of airway pressure release ventilation with maintained unsupported spontaneous breathing (APRV) and synchronized intermittent mandatory ventilation with pressure support (SIMV) on the amount of lung collapse in acute lung injury patients. Thirty-seven patients with acute lung injury were studied in a trial comparing APRV or SIMV. Computer-assisted tomography scannings (CT) were performed before randomization and at day 7. The change in the amount of nonaerated lung was comparable between groups; 14.7% (3.8-17.4) in APRV group (n = 13) and 9.6% (—1.4 to 18.62) in the SIMV group (n = 10), (P = .65, difference in mean 4.9%, 95% confidence interval —9.0% to 19.0%). The effects of APRV and SIMV on lung aeration are similar after 7 days of mechanical ventilation. |
| تدمد: | 1525-1489 0885-0666 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dcadab6c99e1c1dc545dd7b4bff16eTest https://doi.org/10.1177/0885066608330098Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....d8dcadab6c99e1c1dc545dd7b4bff16e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15251489 08850666 |
|---|