المؤلفون: Karin C A A Wildhagen, Roy Schrijver, Linda Beckers, Hugo ten Cate, Chris P M Reutelingsperger, Esther Lutgens, Gerry A F Nicolaes

المصدر: PLoS ONE, Vol 9, Iss 7, p e101446 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC4102480?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/dc009b25dd374f87926379fe14bdd14dTest

المؤلفون: Janneke Horn, Maryse A. Wiewel, Tom van der Poll, Marcus J. Schultz, Karin C. A. A. Wildhagen, Roy Schrijver, Chris P. M. Reutelingsperger, Gerry A. F. Nicolaes

المساهمون: Graduate School, AII - Amsterdam institute for Infection and Immunity, Intensive Care Medicine, ANS - Amsterdam Neuroscience, Infectious diseases, Center of Experimental and Molecular Medicine, Promovendi CD, Biochemie, RS: CARIM - R1 - Thrombosis and haemostasis

المصدر: Thrombosis research, 136(3), 542-547. Elsevier Limited
Thrombosis Research, 136(3), 542-547. Elsevier Science

مصطلحات موضوعية: Male, medicine.medical_specialty, Thrombin generation, Antithrombin, Inflammation, Biology, Sensitivity and Specificity, Antithrombins, law.invention, Sepsis, Histones, chemistry.chemical_compound, law, Risk Factors, Internal medicine, Lactate dehydrogenase, medicine, Extracellular, Humans, Platelet, Mortality, Tissue homeostasis, Hydro-Lyases, Netherlands, Platelet Count, Incidence, Reproducibility of Results, NETosis, Hematology, Middle Aged, medicine.disease, Prognosis, Intensive care unit, Survival Rate, Endocrinology, chemistry, Immunology, Female, medicine.symptom, Biomarkers, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f38d944b46cacbae0691d1432d6f78Test
https://cris.maastrichtuniversity.nl/en/publications/183d6dc8-7668-4e10-bf40-bf83d8065d63Test

المؤلفون: Gerry A. F. Nicolaes, Olivier Sperandio, Roy Schrijver, Bruno O. Villoutreix, Karin C. A. A. Wildhagen, Simone J.H. Wielders

المساهمون: Promovendi CD, Ondersteunend personeel CD, Biochemie, RS: CARIM - R1 - Thrombosis and haemostasis

المصدر: Thrombosis Research, 133(6), 1105-1114. Elsevier Science

مصطلحات موضوعية: Models, Molecular, Virtual screening, Protein Data Bank (RCSB PDB), Drug Evaluation, Preclinical, Drug design, Small Molecule Libraries, Structure-Activity Relationship, Thrombin, medicine, Humans, Binding site, Protein C Inhibitor, chemistry.chemical_classification, Binding Sites, Chemistry, Binding protein, Hematology, computer.file_format, Surface Plasmon Resonance, Protein Data Bank, Small molecule, Enzyme, Activated protein C, Biochemistry, Factor Va, computer, medicine.drug, Protein C

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cc4cf2e16c7771e3d0bf2c052c7733Test
https://doi.org/10.1016/j.thromres.2014.01.026Test

المؤلفون: Linda Beckers, Gerry A. F. Nicolaes, Hugo ten Cate, Chris P. M. Reutelingsperger, Karin C. A. A. Wildhagen, Roy Schrijver, Esther Lutgens

المساهمون: Promovendi CD, Ondersteunend personeel NTM, MUMC+: MA Alg Interne Geneeskunde (9), Interne Geneeskunde, Pathologie, Biochemie, RS: CARIM - R1 - Thrombosis and haemostasis, RS: CARIM - R3 - Vascular biology, Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam institute for Infection and Immunity

المصدر: PLoS ONE, Vol 9, Iss 7, p e101446 (2014)
PLoS ONE
PLOS ONE, 9(7):e101446. Public Library of Science
PLoS ONE, 9(7), e101446-(10 p.). Public Library of Science

مصطلحات موضوعية: Male, Myocardial Infarction, lcsh:Medicine, Biochemistry, Vascular Medicine, Mice, Spectrum Analysis Techniques, Ischemia, Medicine and Health Sciences, Receptor, lcsh:Science, Immune Response, Chemokine CCL2, Mice, Knockout, Endothelial protein C receptor, Innate Immune System, Multidisciplinary, Endothelial Protein C Receptor, Heart, Animal Models, Flow Cytometry, Recombinant Proteins, Interleukin-10, Spectrophotometry, Reperfusion Injury, Cytokines, Cytophotometry, medicine.symptom, Coagulation Factors, medicine.drug, Research Article, medicine.medical_specialty, Immunology, Cardiology, Inflammation, Mouse Models, Receptors, Cell Surface, CCL2, Research and Analysis Methods, Cell Line, Thrombin, Model Organisms, Apolipoproteins E, Antigens, CD, Internal medicine, medicine, Animals, Humans, Receptor, PAR-1, Animal Models of Disease, Immunoassays, Immunohistochemistry Techniques, business.industry, Interleukin-6, lcsh:R, Biology and Life Sciences, Proteins, Molecular Development, medicine.disease, Atherosclerosis, Histochemistry and Cytochemistry Techniques, Mice, Inbred C57BL, Endocrinology, HEK293 Cells, Cytoprotection, Immune System, Animal Studies, Immunologic Techniques, lcsh:Q, business, Reperfusion injury, Protein C, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842f2d90df0a2bf5ef2c8e81a88397e4Test
http://europepmc.org/articles/PMC4102480?pdf=renderTest

المؤلفون: Oliver Soehnlein, Cristina Aresté, Chris P. M. Reutelingsperger, Gerry A. F. Nicolaes, Almudena Ortega-Gomez, Karin C. A. A. Wildhagen, H. Coenraad Hemker, Roy Schrijver, Niko Deckers, Pablo García de Frutos

المساهمون: Netherlands Organization for Scientific Research, Cardiovascular Research Institute Maastricht, German Research Foundation, Pathology, Promovendi CD, Ondersteunend personeel CD, Bedrijfsbureau CD, Pathologie, Biochemie, RS: CARIM - R1 - Thrombosis and haemostasis, RS: CARIM - R3 - Vascular biology

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Blood, 123(7), 1098-1101. American Society of Hematology
Blood, 123(7), 1098-1101. The American Society of Hematology

مصطلحات موضوعية: Drug, Lipopolysaccharides, medicine.medical_specialty, medicine.drug_class, media_common.quotation_subject, Immunology, In vitro cytotoxicity, Pharmacology, Chemical Fractionation, Biochemistry, Sepsis, Histones, Mice, Extracellular, Medicine, Animals, Intensive care medicine, Survival analysis, Cells, Cultured, media_common, biology, Dose-Response Relationship, Drug, business.industry, Heparin, Anticoagulant, Anticoagulants, Cell Biology, Hematology, medicine.disease, Survival Analysis, Mice, Inbred C57BL, Histone, Cytoprotection, biology.protein, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44be8a0a11f08638e61f080a61c38995Test
https://pubmed.ncbi.nlm.nih.gov/24526772Test

المؤلفون: Jan Rosing, Paul E. Bock, Karin C. A. A. Wildhagen, Björn Dahlbäck, Gerry A. F. Nicolaes, Kenneth Segers

المساهمون: Biochemie, Promovendi CD, RS: CARIM School for Cardiovascular Diseases

المصدر: Journal of Biological Chemistry, 285(30), 22888-22898. American Society for Biochemistry and Molecular Biology, Inc.

مصطلحات موضوعية: Models, Molecular, Cleavage (embryo), Arginine, Biochemistry, Binding, Competitive, Protein S, Cell Line, Enzyme activator, Thrombin, Zymogen, Catalytic Domain, medicine, Humans, Molecular Biology, Blood Coagulation, biology, Chemistry, Protein Stability, Active site, Cell Biology, Blood Coagulation Factors, Recombinant Proteins, Neoplasm Proteins, Enzyme Activation, Cysteine Endopeptidases, Docking (molecular), Mutation, biology.protein, Enzymology, Protein C, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6723bea6e045983fcb71a3226b420dTest
https://pubmed.ncbi.nlm.nih.gov/20484050Test