دورية أكاديمية

Consensus statement from the first RdRp Summit: advancing RNA virus discovery at scale across communities

التفاصيل البيبلوغرافية
العنوان: Consensus statement from the first RdRp Summit: advancing RNA virus discovery at scale across communities
المؤلفون: Charon, J., Olendraite, I., Forgia, M., Chong, L.C., Hillary, L.S., Roux, S., Kupczok, A., Debat, H., Sakaguchi, S., Tahzima, R., Nakagawa, S., Babaian, A., Abroi, A., Bejerman, N., Ben Mansour, K., Brown, K., Butkovic, A., Cervera, Amelia, Charriat, F., Chen, G., Chiba, Y., De Coninck, L., Demina, T., Dominguez-Huerta, Guillermo, Dubrulle, J., Gutierrez, S., Harvey, E., Jayaraj Mallika, F.R., Karapliafis, D., Lim, S.J., Kasibhatla, S.M., Mifsud, J.C.O., Nishimura, Y., Ortiz-Baez, A.S., Raco, M., Rivero, R., Sadiq, S., Saghaei, S., San, J.E., Shaikh, H.M., Sieradzki, E.T., Sullivan, M.B., Sun, Y., Wille, M., Wolf, Y.I., Zrelovs, N., Neri, U.
المساهمون: European Research Council, Ministerio de Ciencia e Innovación (España)
بيانات النشر: Frontiers Media
سنة النشر: 2024
المجموعة: Digital.CSIC (Consejo Superior de Investigaciones Científicas / Spanish National Research Council)
الوصف: Improved RNA virus understanding is critical to studying animal and plant health, and environmental processes. However, the continuous and rapid RNA virus evolution makes their identification and characterization challenging. While recent sequence-based advances have led to extensive RNA virus discovery, there is growing variation in how RNA viruses are identified, analyzed, characterized, and reported. To this end, an RdRp Summit was organized and a hybrid meeting took place in Valencia, Spain in May 2023 to convene leading experts with emphasis on early career researchers (ECRs) across diverse scientific communities. Here we synthesize key insights and recommendations and offer these as a first effort to establish a consensus framework for advancing RNA virus discovery. First, we need interoperability through standardized methodologies, data-sharing protocols, metadata provision and interdisciplinary collaborations and offer specific examples as starting points. Second, as an emergent field, we recognize the need to incorporate cutting-edge technologies and knowledge early and often to improve omic-based viral detection and annotation as novel capabilities reveal new biology. Third, we underscore the significance of ECRs in fostering international partnerships to promote inclusivity and equity in virus discovery efforts. The proposed consensus framework serves as a roadmap for the scientific community to collectively contribute to the tremendous challenge of unveiling the RNA virosphere. ; The author(s) declare financial support was received for the research, authorship, and/or publication of this article. JC was supported by the French National Research Agency (ANR-21-CE35-0009). UN was supported by the European Research Council (ERC-AdG 787514) and by a fellowship from the Edmond J. Safra Center for Bioinformatics at Tel Aviv University, and by fellowship from the Shmunis School of Biomedicine and Cancer Research. The work conducted by the U.S. Department of Energy Joint Genome Institute (S.R.) ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2673-818X
العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-116008GB-I00/ES/CARACTERIZACION DE NUEVOS RIBOZIMAS DE AUTOCORTE Y RNAS CIRCULARES EN EUCARIOTAS: MECANISMOS, FUNCIONES Y POTENCIAL APLICACION BIOTECNOLOGICA/; Publisher's version; https://doi.org/10.3389/fviro.2024.1371958Test; Sí; Frontiers in Virology 4 : 1371958 (2024); http://hdl.handle.net/10261/353328Test
DOI: 10.3389/fviro.2024.1371958
الإتاحة: https://doi.org/10.3389/fviro.2024.1371958Test
http://hdl.handle.net/10261/353328Test
حقوق: open
رقم الانضمام: edsbas.B112BA07
قاعدة البيانات: BASE
الوصف
تدمد:2673818X
DOI:10.3389/fviro.2024.1371958