المؤلفون: Negin Khosraviani, Karan J. Abraham, Janet N.Y. Chan, Karim Mekhail

المصدر: STAR Protocols, Vol 3, Iss 4, Pp 101734- (2022)

مصطلحات موضوعية: Cell biology, Cell culture, Genetics, Molecular biology, Gene expression, CRISPR, Science (General), Q1-390

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2666166722006141Test; https://doaj.org/toc/2666-1667Test

الوصول الحر: https://doaj.org/article/689e44a373c74c0bb4d5297b33ee6e6eTest

المؤلفون: Roxanne Oshidari, Jonathan Strecker, Daniel K. C. Chung, Karan J. Abraham, Janet N. Y. Chan, Christopher J. Damaren, Karim Mekhail

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/4320e998628b46a9b1f9a18feb648d85Test

المؤلفون: Karan J. Abraham, Miling Wang, Jack Greenblatt, Lauren A. Ostrowski, Aparna Gorthi, Parasvi S. Patel, Daniel D. De Carvalho, Razq Hakem, Michael Ohh, Roxanne Oshidari, Alexander J.R. Bishop, Violena Pietrobon, Anas Samman, Arash Algouneh, Dorothy Yanling Zhao, Stephen Lee, Michael Bokros, Janet N.Y. Chan, V Talya Yerlici, Rajat Singhania, Brendan C. Dickson, Yupeng Liu, Elva Vidya, Negin Khosraviani, Karim Mekhail

المصدر: Nature

مصطلحات موضوعية: RNA, Untranslated, Nucleolus, Ribonuclease H, Ribosome biogenesis, Sarcoma, Ewing, DNA, Ribosomal, Ribosome, Article, RNA polymerase III, 03 medical and health sciences, 0302 clinical medicine, RNA Polymerase I, CRISPR-Associated Protein 9, Cell Line, Tumor, RNA polymerase I, Humans, Polymerase, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, Chemistry, DNA Helicases, RNA, Ribosomal RNA, Multifunctional Enzymes, Cell biology, Protein Biosynthesis, biology.protein, DNA, Intergenic, RNA Polymerase II, R-Loop Structures, Ribosomes, Cell Nucleolus, RNA Helicases, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820ff88977654b593a99a0f867f02a98Test
https://doi.org/10.1038/s41586-020-2497-0Test

المؤلفون: Katrina Mekhail, Karan J. Abraham, Chan Jny, Negin Khosraviani

مصطلحات موضوعية: Genetics, R-loop, Chemistry, Proximal site, Locus (genetics), Trans-acting, Psychological repression, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::004a96d083865a4f769b78f86a75a015Test
https://doi.org/10.1101/2021.05.25.445644Test

المؤلفون: Anne Hakem, Parasvi S. Patel, Jonathan St-Germain, Marie-jo Halaby, Razqallah Hakem, Francesca Mateo, Daniel R. Barnes, Jonathan Beesley, Haithem Barbour, Karim Mekhail, Miquel Angel Pujana, El Bachir Affar, Cheryl H. Arrowsmith, Brian Raught, Samah El Ghamrasni, Arash Algouneh, Kiran Kumar Naidu Guturi, Otto Sanchez, Brandon Ho, Georgia Chenevix-Trench, Shili Duan, Antonis C. Antoniou, Zahra Khan, Karan J. Abraham, Hal K. Berman, Grant W. Brown, Luis Palomero

المساهمون: Barnes, Daniel [0000-0002-3781-7570], Antoniou, Antonis [0000-0001-9223-3116], Apollo - University of Cambridge Repository

المصدر: J Clin Invest

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Poly ADP ribose polymerase, Ubiquitin-Protein Ligases, Mammary Neoplasms, Animal, Mouse models, Genomic Instability, 03 medical and health sciences, Mice, 0302 clinical medicine, Germline mutation, Breast cancer, Animals, Humans, Molecular genetics, skin and connective tissue diseases, Gene, Polymerase, BRCA2 Protein, Mice, Knockout, Ovarian Neoplasms, biology, BRCA1 Protein, Helicase, General Medicine, Cell Biology, DNA, Neoplasm, RNA Helicase A, Ubiquitin ligase, 030104 developmental biology, Oncology, Genetic Loci, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fe09874518ecab3f221c045d16ccb1Test
https://www.repository.cam.ac.uk/handle/1810/317678Test

المؤلفون: Brandon Ho, Grant W. Brown, Samuel A. Killackey, Ru Guo, Janet N.Y. Chan, Karim Mekhail, Nancy X. Liu, Elva Vidya, Amanda C. Hall, Jeffrey E. Lee, Jayesh S. Salvi, Karan J. Abraham

المصدر: Nucleic Acids Research

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Calorie restriction, Saccharomyces cerevisiae, Biology, Genomic Instability, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Yeasts, Genetics, Humans, Magnesium, Molecular Biology, Gene, Magnesium ion, Caloric Restriction, Membrane transport protein, RNA, DNA, biology.organism_classification, 030104 developmental biology, Biochemistry, chemistry, biology.protein, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e223be88a8b1ac98909bdc8c569debTest
https://doi.org/10.1093/nar/gkw752Test

المؤلفون: Karan J. Abraham

المصدر: Clinical and investigative medicine. Medecine clinique et experimentale. 41

مصطلحات موضوعية: Sociology of scientific knowledge, Canada, Biomedical Research, education, Perspective (graphical), Mindset, General Medicine, Training Support, humanities, Research Personnel, Management, Human disease, Basic research, Humans, Sociology, health care economics and organizations, Societies, Medical

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4199ca3d2250bd8dcc049d4195c0b93Test
https://pubmed.ncbi.nlm.nih.gov/30394272Test

المؤلفون: Janet N.Y. Chan, Lauren A. Ostrowski, Ashley Wang, Ru Guo, Kirk Szafranski, Christian Krustev, Kevin Zhang, Yupeng Liu, Karim Mekhail, Roxanne Oshidari, Amanda C. Hall, Karan J. Abraham

المصدر: Communications Biology
Communications Biology, Vol 1, Iss 1, Pp 1-17 (2018)

مصطلحات موضوعية: 0301 basic medicine, Neurodegeneration, Medicine (miscellaneous), Retrotransposon, Protein aggregation, Biology, medicine.disease, Non-coding RNA, General Biochemistry, Genetics and Molecular Biology, Article, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, lcsh:Biology (General), Ataxin, Genetic model, Spinocerebellar ataxia, medicine, General Agricultural and Biological Sciences, Ribosomal DNA, lcsh:QH301-705.5, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8079f4d6f73434fbdfbf98e0d2e6f7faTest
http://europepmc.org/articles/PMC6218562Test

المؤلفون: Victor A. Tron, Ricardo Vidal, Harriet Feilotter, Xiao Zhang, Karan J. Abraham, Geneviève C. Paré

المصدر: The American Journal of Pathology. 186:1025-1035

مصطلحات موضوعية: 0301 basic medicine, Skin Neoplasms, Cellular differentiation, Notch signaling pathway, Down-Regulation, Biology, Cell fate determination, Neuroendocrine differentiation, Pathology and Forensic Medicine, 03 medical and health sciences, Mir-375, medicine, Humans, Cell Lineage, Receptor, Notch2, RBPJ, Merkel cell carcinoma, food and beverages, Cell Differentiation, medicine.disease, Carcinoma, Merkel Cell, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Immunology, Cancer cell, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1db52efd44d934024145fae080460c8Test
https://doi.org/10.1016Test/j.ajpath.2015.11.020

المؤلفون: Karan J. Abraham, Roxanne Oshidari, Jonathan Strecker, Daniel K.C. Chung, Christopher J. Damaren, Karim Mekhail, Janet N.Y. Chan

المصدر: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Saccharomyces cerevisiae Proteins, genetic structures, DNA Repair, Intravital Microscopy, DNA damage, DNA repair, Science, General Physics and Astronomy, Cell Cycle Proteins, Saccharomyces cerevisiae, Microtubules, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Microtubule, Nuclear pore, lcsh:Science, Cell Nucleus, Multidisciplinary, Chemistry, General Chemistry, Chromatin, Cell biology, 030104 developmental biology, Kinesin, lcsh:Q, sense organs, Microtubule-Associated Proteins, DNA, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adff0847d3fa5893f155ff8d7acaf89Test
https://pubmed.ncbi.nlm.nih.gov/29967403Test