المؤلفون: Ronald A. Merrill, Andrew Y. Usachev, Jianing Song, Stefan Strack

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Doublecortin Domain Proteins, 0301 basic medicine, proteasomal degradation, X-linked intellectual disability, PACAP, pituitary adenylate cyclase-activating polypeptide, CRL, cullin-RING ligase, dendritic complexity, MAP, microtubule-associated protein, Gene mutation, Biochemistry, pulse-chase, XLID, X-linked intellectual disability, AUC, area under the curve, ERK, extracellular signal-regulated kinase, Ubiquitin, PP2A, protein phosphatase 2A, Chlorocebus aethiops, GFP, green fluorescent protein, Neurons, biology, KLHL, Kelch-like, DCX, doublecortin, Microfilament Proteins, IP, immunoprecipitation, Editors' Pick, Ubiquitin ligase, Cell biology, E3 ubiquitin ligase, Cul3, cullin3, COS Cells, BDNF, brain-derived neurotrophic factor, doublecortin-like kinases, Microtubule-Associated Proteins, Research Article, neurite outgrowth, Doublecortin Protein, Ubiquitin-Protein Ligases, Blotting, Western, Protein degradation, ubiquitination, Gene product, 03 medical and health sciences, TMR, tetramethyl rhodamine, Intellectual Disability, GST, glutathione-S-transferase, medicine, Animals, Humans, Immunoprecipitation, Gene silencing, Molecular Biology, Trk, tropomyosin-related kinase, 030102 biochemistry & molecular biology, protein phosphatase 2A, protein turnover, Neuropeptides, DCLK, doublecortin-like kinase, Cell Biology, medicine.disease, microtubule-associated protein, Doublecortin, HEK293 Cells, 030104 developmental biology, Proteostasis, Proteasome, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1eea79e2770ecc33f6d9789a83e9183Test
https://doi.org/10.1074/jbc.ra120.016210Test

المؤلفون: Bulatov, Emil, Ciulli, Alessio

المصدر: Biochemical Journal

مصطلحات موضوعية: Models, Molecular, Skp2, S-phase kinase-associated protein 2, Fbxl, F-box/leucine-rich motif-containing protein, SCF, Skp1–Cdc53–F-box Cdc4, DDB, damage-specific DNA-binding protein, DCAF, DDB1–Cul4A-associated factor, EloBC, ElonginB–ElonginC complex, Review Article, SV5, simian virus 5, Nrf2, nuclear factor-erythroid 2-related factor 2, Vpr, viral protein R, JA-Ile, jasmonoyl-isoleucine, CRL, Cullin–RING E3 ubiquitin ligase, HERC2, HECT domain- and RLD (regulator of chromosome condensation 1 protein-like domain) domain-containing E3 ubiquitin protein ligase 2, BCR, BTB–Cul3–Rbx1, Drug Discovery, NAE, NEDD8-activating enzyme, KLHL, Kelch-like protein, Ub, ubiquitin, IκB, inhibitor of NF-κB, Vif, virion infectivity factor, Molecular Structure, ITC, isothermal titration calorimetry, CPH, conserved within Cul7, PARC and HERC2, Cpd, compound, Aux, auxin, Cullin Proteins, structure-based design, CTD, C-terminal domain, Protac, proteolysis-targeting chimaeric molecule, Cul, Cullin, Fbw/Fbxw, F-box/WD repeat-containing protein, STAT, signal transducer and activator of transcription, GHR, growth hormone receptor, UBL, ubiquitin-like protein, FP, fluorescence polarization, NF-κB, nuclear factor κB, Cks1, cyclin-dependent protein kinase regulatory subunit 1, Rbx1, RING-box protein 1, Proteasome Inhibitors, SH2, Src homology 2, assembly, SPOP, speckle-type POZ protein, UPS, ubiquitin–proteasome system, PARC, p53-associated parkin-like cytoplasmic protein, β-TrCP, β-transducin repeat-containing protein, PPI, protein–protein interaction, small molecule, JAZ1, jasmonate/ZIM (zinc finger expressed in inflorescence) domain protein 1, Fbxo, F-box/other domain-containing protein, mTOR, mammalian target of rapamycin, NEDD, neural-precursor-cell-expressed developmentally down-regulated, ubiquitination, APC/C, anaphase-promoting complex/cyclosome, MEL26, maternal effect lethal 26, RING, really interesting new gene, CAND1, Cullin-associated NEDD8-dissociated protein 1, Cdc, cell division cycle, ubiquitin, Ubc12, ubiquitin-conjugating enzyme 12, COI1, coronatine-insensitive protein 1, CSA, Cockayne syndrome A, Humans, structure, NTD, N-terminal domain, CRBN, cereblon, Protein Structure, Quaternary, SMER3, small-molecule enhancer of rapamycin 3, CSN, COP9 (constitutive photomorphogenesis 9) signalosome complex, CBFβ, core binding factor β, IAA, indole-3-acetic acid, SOCS, suppressor of cytokine signalling, BTB, bric-a-brac/tramtrack/broad complex, MATH, meprin and TRAF (tumour necrosis factor receptor-associated factor) homology, Keap1, Kelch-like enoyl-CoA hydratase-associated protein 1, Protein Structure, Tertiary, VHL, von Hippel–Lindau, Protein Subunits, ASB, ankyrin repeat and SOCS-box, BP, β-propeller, HECT, homologous with E6-associated protein C-terminus, Drug Design, HIF-1α, hypoxia-inducible factor 1α, VPRBP, Vpr-binding protein, TIR1, transport inhibitor response 1, POZ, pox virus and zinc finger

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::5b07715f4217b08830d90ae742dc138fTest
http://europepmc.org/articles/PMC4403949Test

المؤلفون: Canning, Peter, Bullock, Alex N.

المصدر: Biochemical Society Transactions

مصطلحات موضوعية: SPOP, speckle-type POZ protein, antioxidant response, drug design, BTB, broad complex/tramtrack/bric-à-brac, MATH, meprin and TRAF (tumour-necrosis-factor-receptor-associated factor) homology, Nrf2, nuclear factor erythroid 2-related factor 2, S5, Protein Structure, Secondary, Rbx, RING box protein, RING, really interesting new gene, cancer, Humans, ARE, antioxidant-response element, Molecular Targeted Therapy, ubiquitylation, Protein Structure, Quaternary, Biochemical Society Focused Meeting, degradation, Kelch-Like ECH-Associated Protein 1, KLHL, Kelch-like, BACK, BTB and C-terminal Kelch, Intracellular Signaling Peptides and Proteins, Ubiquitination, cell signalling, Cullin Proteins, Protein Structure, Tertiary, CRL, Cullin–RING ligase, HECT, homologous with E6-associated protein C-terminus, Multiprotein Complexes, KEAP1, Kelch-like ECH-associated protein 1, POZ, pox virus and zinc finger

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::839c55b704708e46a63bc6a374e7ab21Test
https://ora.ox.ac.uk/objects/uuid:92171bca-21d7-40fe-9f4e-b174e8406f7dTest

المؤلفون: Frances-Rose, Schumacher, Fiona J, Sorrell, Dario R, Alessi, Alex N, Bullock, Thimo, Kurz

المصدر: Biochemical Journal

مصطلحات موضوعية: RT-PCR, reverse transcription–PCR, hypertension, Amino Acid Motifs, SPAK, SPS1-related proline/alanine-rich kinase, CUL3, Cullin3, Blood Pressure, Nerve Tissue Proteins, NKCC2, Na+/K+/2Cl− co-transporter 2, Protein Serine-Threonine Kinases, NCC, Na+/Cl− ion co-transporter, Crystallography, X-Ray, Cullin, TEV, tobacco etch virus, Minor Histocompatibility Antigens, Kelch-like protein (KLHL), BTB, Bric-a-brac, Tramtrack, and Broad complex, OSR1, oxidative stress-responsive kinase 1, rTEV, recombinant tobacco etch virus, WNK Lysine-Deficient Protein Kinase 1, NRF2, nuclear factor-erythroid 2-related factor 2, ubiquitin, Humans, Tramtrack, KLHL, Kelch-like protein, Adaptor Proteins, Signal Transducing, WNK, with no lysine (K), TCEP, tris-(2-carboxyethyl)phosphine, urogenital system, Microfilament Proteins, Intracellular Signaling Peptides and Proteins, Ubiquitination, Cullin Proteins, and Broad complex (BTB domain), KEAP1, Kelch-like enoyl-CoA hydratase-associated protein 1, Bric-a-brac, CRL3KLHL3, Cullin3-RING ligase in complex with KLHL, Carrier Proteins, Crystallization, Kelch-like protein 2 (KLHL2), Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::c699dff86d0d9b6d522a45504cb2d9cfTest
https://pubmed.ncbi.nlm.nih.gov/24641320Test