المؤلفون: Brandt, Claudia, Seja, Patricia, Töllner, Kathrin, Römermann, Kerstin, Hampel, Philip, Kalesse, Markus, Kipper, Andi, Feit, Peter W., Lykke, Kasper, Toft-Bertelsen, Trine Lisberg, Paavilainen, Pauliina, Spoljaric, Inkeri, Puskarjov, Martin, MacAulay, Nanna, Kaila, Kai, Löscher, Wolfgang

المساهمون: Laboratory of Neurobiology, Neuroscience Center, University of Helsinki, Helsinki Institute of Life Science HiLIFE, Physiology and Neuroscience (-2020), Molecular and Integrative Biosciences Research Programme, Kai Kaila / Principal Investigator

مصطلحات موضوعية: Epilepsy, Anti-seizure drugs, Neonatal seizures, GABA, Giant depolarizing potentials, CATION-CHLORIDE COTRANSPORTERS, WATER PERMEABILITY, PILOCARPINE MODEL, ANIMAL-MODELS, PYRAMIDAL NEURONS, DRUG DISCOVERY, KINDLED RATS, GABA ACTIONS, AQUAPORIN 4, 3112 Neurosciences, 1184 Genetics, developmental biology, physiology

وصف الملف: application/pdf

العلاقة: We thank Biff Forbush, Yale School of Medicine (CT, USA), for providing the hNKCC1a construct and for extensive discussion during preparation of the manuscript, Soren Nielsen, Aarhus University (Denmark) for providing rat AQP4.M23, Thomas Erker (University of Vienna) for providing an initial sample of bumepamine, and Andrea J. Yool, University of Adelaide (Australia), for providing a sample of AqB013. The experiments were supported by the Deutsche Forschungsgemeinschaft (grant number LO 274/15-1) (to WL); the ERC Grant 2013-AdG 341116 (to K.K.); and the Academy of Finland (K.K.); and the Danish Medical Research Council (NM). We thank Edith Kaczmarek, Martina Gramer, and Charlotte Goos Iversen for skillful technical assistance.; Brandt , C , Seja , P , Töllner , K , Römermann , K , Hampel , P , Kalesse , M , Kipper , A , Feit , P W , Lykke , K , Toft-Bertelsen , T L , Paavilainen , P , Spoljaric , I , Puskarjov , M , MacAulay , N , Kaila , K & Löscher , W 2018 , ' Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti seizure efficacy ' , Neuropharmacology , vol. 143 , pp. 186-204 . https://doi.org/10.1016/j.neuropharm.2018.09.025Test; ORCID: /0000-0003-0668-5955/work/53517455; ORCID: /0000-0001-9111-6946/work/53518464; 85056174866; 65942d27-1569-433d-bd84-382c34862e1a; http://hdl.handle.net/10138/312515Test; 000453493200019

الإتاحة: http://hdl.handle.net/10138/312515Test

المؤلفون: Kapucu, A., Ustunova, S., Akgun-Dar, K.

المساهمون: ÜSTÜNOVA, SAVAŞ

مصطلحات موضوعية: Kapucu A., Ustunova S., Akgun-Dar K., Valeriana officinalis extract and 7-Nitroindozole ameliorated seizure behaviours, and 7-Nitroindozole reduced blood pressure and ECG parameters in pentylenetetrazole-kindled rats-, POLISH JOURNAL OF VETERINARY SCIENCES, cilt.23, ss.349-357

الوقت: 2020

العلاقة: http://hdl.handle.net/20.500.12645/27355Test; WOS:000576484200004; 85092679277

الإتاحة: https://doi.org/20.500.12645/27355Test
https://doi.org/10.24425/pjvs.2020.133652Test
https://hdl.handle.net/20.500.12645/27355Test

المؤلفون: Kai Kaila, Kerstin Römermann, Pauliina Paavilainen, Trine Lisberg Toft-Bertelsen, Andi Kipper, Peter W. Feit, Inkeri Spoljaric, Wolfgang Löscher, Martin Puskarjov, Patricia Seja, Nanna MacAulay, Kathrin Töllner, Markus Kalesse, Philip Hampel, Claudia Brandt, Kasper Lykke

المساهمون: Laboratory of Neurobiology, Neuroscience Center, University of Helsinki, Helsinki Institute of Life Science HiLIFE, Physiology and Neuroscience (-2020), Molecular and Integrative Biosciences Research Programme, Kai Kaila / Principal Investigator

مصطلحات موضوعية: 0301 basic medicine, Benzylamines, medicine.medical_treatment, Drug Evaluation, Preclinical, Pharmacology, Hippocampal formation, Tissue Culture Techniques, Epilepsy, Mice, Xenopus laevis, GABA, 0302 clinical medicine, Sodium Potassium Chloride Symporter Inhibitors, AQUAPORIN 4, Solute Carrier Family 12, Member 2, KINDLED RATS, Bumetanide, PILOCARPINE MODEL, Chemistry, 1184 Genetics, developmental biology, physiology, Brain, Drug Synergism, PYRAMIDAL NEURONS, Loop diuretic, 3. Good health, ANIMAL-MODELS, Pilocarpine, Phenobarbital, Anticonvulsants, Female, CATION-CHLORIDE COTRANSPORTERS, medicine.drug, medicine.drug_class, 03 medical and health sciences, Cellular and Molecular Neuroscience, Giant depolarizing potentials, Seizures, medicine, Animals, Rats, Wistar, GIANT DEPOLARIZING POTENTIALS, 3112 Neurosciences, WATER PERMEABILITY, Neonatal seizures, medicine.disease, DRUG DISCOVERY, 030104 developmental biology, Anticonvulsant, GABA ACTIONS, Oocytes, 030217 neurology & neurosurgery, Anti-seizure drugs

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb498b43ac7a92429d3b6c29ccfcc27Test
http://hdl.handle.net/10138/312515Test

المؤلفون: Wilcox, K. S., Dixon-Salazar, T., Sills, G. J., Ben-Menachem, Elinor, 1945, White, H. S., Porter, R. J., Dichter, M. A., Moshe, S. L., Noebels, J. L., Privitera, M. D., Rogawski, M. A.

المصدر: Epilepsia. 54:24-34

مصطلحات موضوعية: Clinical Medicine, Klinisk medicin, Antiseizure drug, Pharmacoresistant epilepsy, Animal models of epilepsy, temporal-lobe epilepsy, resistant kindled rats, spontaneous recurrent, seizures, anticonvulsant screening-program, kainate-induced epilepsy, phenytoin-resistant, antiepileptic drugs, mouse model, status, epilepticus, pharmacological characterization

الوصول الحر: https://gup.ub.gu.se/publication/182770Test

المؤلفون: Moldrich, RX, Jeffrey, M, Talebi, A, Beart, PM, Chapman, AG, Meldrum, BS

مصطلحات موضوعية: Neurosciences, Pharmacology & Pharmacy, glutamate metabotropic receptors, mGlu(2), mGlu(3), anticonvulsant, DBA/2 mice, lethargic (lh/lh) mice, genetically epilepsy-prone rats, amygdala-kindled rats, (R,S)-3,5-dihydroxyphenylglycine, (+)-2-aminobicyclo<3.1.0>hexane-2,6-dicarboxylic Acid Ly354740, Seizure Activity, Pharmacological Characterization, Anticonvulsant Action, Calcium Channels, Rat Hippocampus, Beta-subunit, Dcg-iv, Potent, Mice

الإتاحة: https://doi.org/10.1016/S0028-3908Test(01)00044-2
https://espace.library.uq.edu.au/view/UQ:122111Test

المؤلفون: An Analysis, Environmental Habituation, Devon Andersen

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://ecommons.usask.ca/bitstream/handle/10388/etd-09142007-085640/DevonAndersenThesis.pdfTest.

مصطلحات موضوعية: Habituation in Kindled Rats

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.588.4466Test; http://ecommons.usask.ca/bitstream/handle/10388/etd-09142007-085640/DevonAndersenThesis.pdfTest

الإتاحة: http://ecommons.usask.ca/bitstream/handle/10388/etd-09142007-085640/DevonAndersenThesis.pdfTest