التفاصيل البيبلوغرافية
| العنوان: |
Cell survival of glioblastoma grown in medium containing hydrogen peroxide and/or nitrite, or in plasma-activated medium. |
| المؤلفون: |
Naoyuki Kurake1 kurake.naoyuki@f.mbox.nagoya-u.ac.jp, Hiromasa Tanaka1, Kenji Ishikawa1 ishikawa.kenji@nagoya-u.jp, Takashi Kondo2, Makoto Sekine1, Kae Nakamura3, Hiroaki Kajiyama3, Fumitaka Kikkawa2, Masaaki Mizuno3, Masaru Hori1 |
| المصدر: |
Archives of Biochemistry & Biophysics. Sep2016, Vol. 605, p102-108. 7p. |
| مصطلحات موضوعية: |
*GLIOBLASTOMA multiforme, *HYDROGEN peroxide, *NITRITES |
| Reviews & Products: |
ARCHIVES of Biochemistry & Biophysics (Periodical) |
| People: |
KURAKE, Naoyuki, TANAKA, Hiromasa, ISHIKAWA, Kenji, KONDO, Takashi, NAKAMURA, Kae, KAJIYAMA, Hiroaki, KIKKAWA, Fumitaka, HORI, Masaru |
| مستخلص: |
Non-equilibrium atmospheric pressure plasmas generate a high electron density (on the order of 1016 electrons per cm-3) using Ar gas. Culture medium in air at room temperature was plasma-irradiated for several hundred seconds. Tens of micromolar hydrogen peroxide (H2O2) and millimolar levels of nitrous ion (NO2-) were detected in the plasma-irradiated culture medium (plasma activated medium; PAM) and selectively induced the apoptotic death of glioblastoma tumor cells, but did not kill normal mammary epithelial cells. A similar antitumor effect was induced by spiking the medium with comparable concentrations of H2O2 and NO2-. The PAM remained still a somewhat difference that it should also be assessed for understanding other latent mechanisms. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
