المؤلفون: Pranay Shah, Ross Hill, Camille Dion, Stephen J. Clark, Abdulkadir Abakir, Jeroen Willems, Mark J. Arends, Juan I. Garaycoechea, Harry G. Leitch, Wolf Reik, Gerry P. Crossan

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/9298bed0fab347d4ab08101e4f2d4f6cTest

المؤلفون: Ross J. Hill, Nazareno Bona, Job Smink, Hannah K. Webb, Alastair Crisp, Juan I. Garaycoechea, Gerry P. Crossan

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/f0329d797201440c9a105480326a2843Test

المؤلفون: Juan I. Garaycoechea, Catherine Quinlan, Martijn S. Luijsterburg

المصدر: Nature Reviews Nephrology. 19:229-243

مصطلحات موضوعية: Nephrology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::99fbb0272a14c1a9e3257b4127c1f098Test
https://doi.org/10.1038/s41581-022-00671-zTest

المؤلفون: Lee Mulderrig, Juan I Garaycoechea

المصدر: PLoS Genetics, Vol 16, Iss 4, p e1008555 (2020)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1553-7390Test; https://doaj.org/toc/1553-7404Test

الوصول الحر: https://doaj.org/article/9408b1694fe14de184245a50aa59cd84Test

المؤلفون: Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Yifan Zhao, Hu Jin, Doga Gulhan, Javier Ganz, Sara Bizzotto, Samantha Kirkham, Tino Hochepied, Claude Libert, Alon Galor, Junho Kim, Michael A. Lodato, Juan I. Garaycoechea, Charles Gawad, Jay West, Christopher A. Walsh, Peter J. Park

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Nature Genetics, 54(10), 1564-1571. Nature Publishing Group
NATURE GENETICS
Nat Genet

مصطلحات موضوعية: Neurons, High-Throughput Nucleotide Sequencing/methods, Genome, Human/genetics, INDEL Mutation/genetics, Genome, Human, Nucleotides, High-Throughput Nucleotide Sequencing, Biology and Life Sciences, Polymorphism, Single Nucleotide/genetics, Polymorphism, Single Nucleotide, Article, INDEL Mutation, Genetics, Medicine and Health Sciences, Genome, Human/genetics, Humans, Point Mutation, Polymorphism, Single-Cell Analysis, Single Nucleotide/genetics, SIGNATURES

وصف الملف: application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbfb2ab572d96cf2841204754caaf5dTest
https://pure.knaw.nl/portal/en/publications/c32b40db-e719-45a1-8319-adee9a8a4292Test

المؤلفون: Lee Mulderrig, Juan I. Garaycoechea

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: PLoS Genetics
PLoS Genetics, 16(4). Public Library of Science
PLoS Genetics, Vol 16, Iss 4, p e1008555 (2020)

مصطلحات موضوعية: Male, DNA Repair, Hydrolases, Physical Chemistry, Biochemistry, Endonuclease, Mice, 0302 clinical medicine, Animal Cells, Homeostasis, Cell Cycle and Cell Division, 0303 health sciences, Organic Compounds, Stem Cells, Flow Cytometry, Cell biology, Cross-Linking Reagents/pharmacology, Nucleic acids, Blood, Spectrophotometry, Genetic Diseases, Perspective, Physical Sciences, Cytophotometry, Cellular Types, Nucleases, DNA damage, Kidney/enzymology, Acetaldehyde, 03 medical and health sciences, Tissue Repair, Genetics, Humans, Molecular Biology Techniques, Cockayne Syndrome, Molecular Biology, Ecology, Evolution, Behavior and Systematics, technology, industry, and agriculture, Chemical Compounds, Proteins, nutritional and metabolic diseases, Biology and Life Sciences, DNA, Hematopoietic Stem Cells, Endonucleases, Physiological Processes, 030217 neurology & neurosurgery, Cloning, Cancer Research, Physiology, Synthesis Phase, Endogeny, QH426-470, Kidney, Spectrum Analysis Techniques, Cross-Linking, Medicine and Health Sciences, Homologous Recombination, Genetics (clinical), Tissue homeostasis, Anemia, Hematology, Phenotype, Enzymes, DNA-Binding Proteins, Chemistry, Cross-Linking Reagents, Liver, Cell Processes, Endonucleases/deficiency, Female, Anatomy, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, DNA repair, DNA recombination, Formaldehyde/pharmacology, macromolecular substances, Biology, Research and Analysis Methods, DNA Repair/genetics, Autosomal Recessive Diseases, Formaldehyde, Animals, 030304 developmental biology, Clinical Genetics, Chemical Bonding, Organic Chemistry, Liver/enzymology, Kidneys, Renal System, Cell Biology, Enzymology, biology.protein, ERCC1, DNA-Binding Proteins/deficiency, Nucleotide excision repair, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebca2fc28d56cf824d081b220a44baa2Test
https://pubmed.ncbi.nlm.nih.gov/32271747Test

المؤلفون: Lee Mulderrig, Naomi Park, Serena Nik-Zainal, Frederic Langevin, Juan I. Garaycoechea, Guillaume Guilbaud, Fentang Yang, Gerry P. Crossan, Ketan J. Patel, Sophie Roerink, Sandra Louzada, Michael R. Stratton

المصدر: Nature. 553:171-177

مصطلحات موضوعية: Male, 0301 basic medicine, Genome instability, DNA End-Joining Repair, Cell Survival, DNA damage, Acetaldehyde, Biology, medicine.disease_cause, Genomic Instability, Article, Mice, 03 medical and health sciences, medicine, Animals, DNA Breaks, Double-Stranded, Ku Autoantigen, Mutation, Multidisciplinary, Ethanol, Whole Genome Sequencing, Fanconi Anemia Complementation Group D2 Protein, Alcohol Dehydrogenase, Hematopoietic Stem Cell Transplantation, Recombinational DNA Repair, Genes, p53, Hematopoietic Stem Cells, Cell biology, Mice, Inbred C57BL, Transplantation, Haematopoiesis, Fanconi Anemia, 030104 developmental biology, Female, Tumor Suppressor Protein p53, Stem cell, Homologous recombination, Gene Deletion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8c4f41485eb2814ca4ed75f1c67c97Test
https://doi.org/10.1038/nature25154Test

المؤلفون: Rui Yu, Verena Broecker, Guillermo Burgos-Barragan, James A. Swenberg, Mark J. Arends, Gayathri Chandrasekaran, Ketan J. Patel, Gerry P. Crossan, Lucas B. Pontel, Wei Wei, Limin Liu, Iván V. Rosado, Juan I. Garaycoechea

المساهمون: Universidad de Sevilla. Departamento de Genética, Medical Research Council. UK, Instituto de Salud Carlos III. España, Ministerio de Economía y Competitividad (MINECO). España, National Institute of Environmental Health Sciences (NIEHS). U.S., Texas Commission for Environmental Quality. U.S., Wellcome Trust. UK

المصدر: idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Molecular Cell
Pontel, L B, Rosado, I V, Burgos-Barragan, G, Garaycoechea, J I, Yu, R, Arends, M J, Chandrasekaran, G, Broecker, V, Wei, W, Liu, L, Swenberg, J A, Crossan, G P & Patel, K J 2015, ' Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen ', Molecular Cell, vol. 60, no. 1, pp. 177-188 . https://doi.org/10.1016/j.molcel.2015.08.020Test

مصطلحات موضوعية: DNA damage, Endogeny, Kidney, Article, DNA Adducts, Gene Knockout Techniques, Mice, Formaldehyde, medicine, Animals, Molecular Biology, Carcinogen, Cells, Cultured, Alcohol dehydrogenase, biology, Fanconi Anemia Complementation Group D2 Protein, Alcohol Dehydrogenase, Kidney metabolism, Hematopoietic stem cell, Cell Biology, Hematopoietic Stem Cells, Molecular biology, 3. Good health, Cell biology, Haematopoiesis, medicine.anatomical_structure, Liver, biology.protein, Carcinogens, Stem cell, Mutagens

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8f1fa5e33bd087a5587511933f8814Test

المؤلفون: Ketan J. Patel, Lori A. Passmore, Juan I. Garaycoechea, Eeson Rajendra

المصدر: Nucleic Acids Research

مصطلحات موضوعية: Genome instability, DNA repair, Ataxia Telangiectasia Mutated Proteins, Biology, Genome Integrity, Repair and Replication, Cell Line, chemistry.chemical_compound, Fanconi anemia, Chromosome instability, Genetics, RUVBL2, medicine, Animals, Humans, Gene, Adenosine Triphosphatases, Mice, Knockout, DNA Helicases, Anemia, Aplastic, DNA Repair Pathway, medicine.disease, Hematopoietic Stem Cells, Molecular biology, Fanconi Anemia Complementation Group Proteins, Cross-Linking Reagents, chemistry, ATPases Associated with Diverse Cellular Activities, Carrier Proteins, Chickens, DNA, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56df4227f8207ef12c9891eba9152625Test
http://europepmc.org/articles/PMC4267650Test

المؤلفون: Juan I. Garaycoechea, Jan Silhan, Orlando D. Schärer, Shivam Mukherjee, Michael R. G. Hodskinson, Gerry P. Crossan, Ketan J. Patel, Christopher M. Johnson

المصدر: Molecular Cell

مصطلحات موضوعية: Genome instability, DNA Repair, DNA damage, DNA repair, Bone Marrow Cells, Mice, Transgenic, macromolecular substances, Biology, Article, Recombinases, DNA Adducts, Mice, chemistry.chemical_compound, Neoplasms, DNA Crosslinking, Animals, Replication protein A, Molecular Biology, Nuclease, Base Sequence, Tumor Suppressor Proteins, technology, industry, and agriculture, Cell Biology, Endonucleases, Hematopoietic Stem Cells, Molecular biology, DNA-Binding Proteins, Mice, Inbred C57BL, chemistry, biology.protein, Nucleic Acid Conformation, DNA, DNA Damage, Nucleotide excision repair

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d241584e6440b138596dda1fde877445Test