المؤلفون: Joneborg, Ulrika, Bergamini, Alice, Wallin, Emelie, Mangili, Giorgia, Solheim, Olesya, Marquina, Gloria, Casado, Antonio, Rokkones, Erik, Coulter, John, Lok, Christianne A R, van Trommel, Nienke, Amant, Frédéric, Bolze, Pierre-Adrien, Sehouli, Jalid, Han, Sileny, Kridelka, Frédéric, Goffin, Frédéric, Pautier, Patricia, Ray-Coquard, Isabelle, Seckl, Michael

المصدر: International Journal of Gynecological Cancer, 33 (10), 1621 - 1626 (2023-10-02)

مصطلحات موضوعية: Gestational Trophoblastic Disease, Ovarian Neoplasms, Sex Cord-Gonadal Stromal Tumors, Trophoblastic Neoplasms, Female, Humans, Off-Label Use, Health Personnel, Europe, Genital Neoplasms, Female/diagnosis, Genital Neoplasms, Female/therapy, Genital Neoplasms, Female, Oncology, Obstetrics and Gynecology, Human health sciences, Sciences de la santé humaine, Oncologie

العلاقة: https://syndication.highwire.org/content/doi/10.1136/ijgc-2023-004599Test; urn:issn:1048-891X; urn:issn:1525-1438

الوصول الحر: https://orbi.uliege.be/handle/2268/310329Test

المؤلفون: Åkerlund, Emma, Gudoityte, Greta, Moussaud-Lamodiere, Elisabeth, Lind, Olina, Bwanika, Henri Colyn, Lehti, Kaisa, Salehi, Sahar, Carlson, Joseph, Wallin, Emelie, Fernebro, Josefin, Ostling, Paivi, Kallioniemi, Olli, Joneborg, Ulrika, Seashore-Ludlow, Brinton

المساهمون: Institute for Molecular Medicine Finland

مصطلحات موضوعية: Bcl-x-l, Precision medicine, Models, Cells, Carcinoma, Inhibition, Expression, Resistance, Survival, Reveals, 3122 Cancers

وصف الملف: application/pdf

العلاقة: B.S.L. acknowledges the Swedish Research Council (2021-03420) and Ake Wibergs Stiftelse (M19-0271). OK acknowledges the Knut and Alice Wallenberg Foundation (KAW 2015.0291), and the Swedish Research Council (2017-06095). We acknowledge Tom Erkers for constructive criticism of the manuscript. BioRender was used for the schematic graphics. Rebecka Bergstroem and Johan Lindberg are acknowledged for panel-sequencing of the patient-derived models used in the manuscript. Lidia Moyano-Galceran and Okan Gultekin are acknowledged for collection of several of the patient samples.Open access funding provided by Karolinska Institute; Åkerlund , E , Gudoityte , G , Moussaud-Lamodiere , E , Lind , O , Bwanika , H C , Lehti , K , Salehi , S , Carlson , J , Wallin , E , Fernebro , J , Ostling , P , Kallioniemi , O , Joneborg , U & Seashore-Ludlow , B 2023 , ' The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients ' , npj precision oncology , vol. 7 , no. 1 , 111 . https://doi.org/10.1038/s41698-023-00463-zTest; http://hdl.handle.net/10138/567946Test; 04401bca-336c-4c1e-ac6d-5de8391b511e; 001096168300001

الإتاحة: http://hdl.handle.net/10138/567946Test

المؤلفون: Pálsdóttir, Kolbrún, Salehi, Sahar, Johansson, Hemming, Groes‐Kofoed, Nina, Falconer, Henrik, Joneborg, Ulrika

المصدر: Acta Obstetricia et Gynecologica Scandinavica ; volume 102, issue 12, page 1653-1660 ; ISSN 0001-6349 1600-0412

الإتاحة: https://doi.org/10.1111/aogs.14674Test

المؤلفون: Coopmans, Leonoor, Larsson, Agnes, Joneborg, Ulrika, Lok, Christianne, van Trommel, Nienke

المصدر: Gynecologic & Obstetric Investigation; 2024, Vol. 89 Issue 3, p214-229, 16p

مصطلحات موضوعية: TROPHOBLASTIC tumors, GESTATIONAL trophoblastic disease, CURETTAGE, TUMOR surgery, ONCOLOGIC surgery, SURGICAL excision, OPERATIVE surgery, TREATMENT effectiveness

المؤلفون: Bergamini, Alice, Joneborg, Ulrika, Marquina, Gloria, Grassi, Elisa, Wallin, Emelie, Casado, Antonio, Solheim, Olesia, Sassu, Carolina Maria, Lok, Christianne AR, Bini, Marta, Pautier, Patricia, Kridelka, Frédéric, Sehouli, Jalid, Nieuwenhuysen, Els Van, Coulter, John, Bolze, Pierre-Adrien, Lebreton, Coriolan, Piek, Jurgen MJ, Ray-Coquard, Isabelle, Seckl, Michael

المصدر: Poster and E-Posters

الإتاحة: https://doi.org/10.1136/ijgc-2024-esgo.1082Test

المؤلفون: Wallin, Emelie, Niemann, Isa, Faaborg, Louise, Fokdal, Lars, Joneborg, Ulrika

المصدر: Wallin , E , Niemann , I , Faaborg , L , Fokdal , L & Joneborg , U 2022 , ' Differences in Administration of Methotrexate and Impact on Outcome in Low-Risk Gestational Trophoblastic Neoplasia ' , Cancers , vol. 14 , no. 3 , 852 . https://doi.org/10.3390/cancers14030852Test

مصطلحات موضوعية: Low risk gestational trophoblastic neoplasia, Methotrexate resistance, Methotrexate treatment, Oral methotrexate

الإتاحة: https://doi.org/10.3390/cancers14030852Test
https://pure.au.dk/portal/da/publications/differences-in-administration-of-methotrexate-and-impact-on-outcome-in-lowrisk-gestational-trophoblastic-neoplasiaTest(0c5b3c1b-4004-4766-9bf7-86920b343ad1).html
http://www.scopus.com/inward/record.url?scp=85124087871&partnerID=8YFLogxKTest

المؤلفون: Moyano-Galceran, Lidia, Pietila, Elina A., Turunen, S. Pauliina, Corvigno, Sara, Hjerpe, Elisabet, Bulanova, Daria, Joneborg, Ulrika, Alkasalias, Twana, Miki, Yuichiro, Yashiro, Masakazu, Chernenko, Anastasiya, Jukonen, Joonas, Singh, Madhurendra, Dahlstrand, Hanna, Carlson, Joseph W., Lehti, Kaisa

المصدر: EMBO Molecular Medicine. 12(4)

مصطلحات موضوعية: chemotherapy, EphA2, GPRC5A, HGSC, resistance

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-411000Test
https://doi.org/10.15252/emmm.201911177Test
https://uu.diva-portal.org/smash/get/diva2:1432565/FULLTEXT01.pdfTest

المؤلفون: Pietilä, Elina A., Gonzalez-Molina, Jordi, Moyano-Galceran, Lidia, Jamalzadeh, Sanaz, Zhang, Kaiyang, Lehtinen, Laura, Turunen, S. Pauliina, Martins, Tomas A., Gultekin, Okan, Lamminen, Tarja, Kaipio, Katja, Joneborg, Ulrika, Hynninen, Johanna, Hietanen, Sakari, Grenman, Seija, Lehtonen, Rainer, Hautaniemi, Sampsa, Carpen, Olli, Carlson, Joseph W., Lehti, Kaisa

المساهمون: Research Program in Systems Oncology, Kaisa Irene Lehti / Principal Investigator, INDIVIDRUG - Individualized Drug Therapy, Sampsa Hautaniemi / Principal Investigator, Research Programs Unit, HUSLAB, Biosciences, Faculty Common Matters (Faculty of Medicine), Bioinformatics, Department of Biochemistry and Developmental Biology, Precision Cancer Pathology, Department of Pathology, Olli Mikael Carpen / Principal Investigator

مصطلحات موضوعية: EXTRACELLULAR-MATRIX, COLLAGEN-VI, METASTASIS, RESISTANCE, APOPTOSIS, INVASION, STROMA, ACTIN, CELLS, 3122 Cancers, 3123 Gynaecology and paediatrics

وصف الملف: application/pdf

العلاقة: We thank Stephen J Weiss and Jaana Oikkonen for comments, Anastasiya Chernenko and Sinikka Kollanus for technical assistance. We also thank the University of Helsinki core facilities Biomedicum Imaging Unit (BIU), Genome Biology Unit (supported by HiLIFE and the Faculty of Medicine) and the Biomedicum Imaging Core (BIC) at Karolinska Institutet. This work was funded by Sigrid Juselius Foundation (to K.L., O.C.), Finnish Cancer Foundation (to K.L., E.A.P., O.C.), Orion Research Foundation (to E.A.P.), K. Albin Johanssons Foundation (to K.L., E.A.P.), Emil Aaltonen Foundation (to E.A.P.), KI Strategic Research Program in Cancer (StratCan-KICancer; to K.L.), Swedish Cancer Society (2015/723, 2018/858 to K.L., J.C.), Swedish Research Council (2019-01541 to K.L.), the European Union's Horizon 2020 research and innovation program under grant agreement No 667403 for HERCULES (to S. Hautaniemi, O.C., S.G.), and the Doctoral Programme in Integrative Life Science (to E.A.P.).; Pietilä , E A , Gonzalez-Molina , J , Moyano-Galceran , L , Jamalzadeh , S , Zhang , K , Lehtinen , L , Turunen , S P , Martins , T A , Gultekin , O , Lamminen , T , Kaipio , K , Joneborg , U , Hynninen , J , Hietanen , S , Grenman , S , Lehtonen , R , Hautaniemi , S , Carpen , O , Carlson , J W & Lehti , K 2021 , ' Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance ' , Nature Communications , vol. 12 , no. 1 , 3904 . https://doi.org/10.1038/s41467-021-24009-8Test; ORCID: /0000-0002-7749-2694/work/100256751; ORCID: /0000-0002-8343-0318/work/100257315; ORCID: /0000-0003-0209-9369/work/100258846; 014f7611-daf8-4b30-b75c-e6f5431f2169; http://hdl.handle.net/10138/334455Test; 000668769000003

الإتاحة: http://hdl.handle.net/10138/334455Test

المؤلفون: Joneborg, Ulrika, Coopmans, Leonoor, van Trommel, Nienke, Seckl, Michael, Lok, Christianne A R

المصدر: International Journal of Gynecologic Cancer ; volume 31, issue 3, page 399-411 ; ISSN 1048-891X 1525-1438

الإتاحة: https://doi.org/10.1136/ijgc-2020-001784Test

المؤلفون: Joneborg, Ulrika, Palsdottir, Kolbrun, Farm, Erik, Johansson, Hemming, Salehi, Sahar

المصدر: European Journal of Surgical Oncology ; volume 47, issue 2, page 353-359 ; ISSN 0748-7983

مصطلحات موضوعية: Oncology, General Medicine, Surgery

الإتاحة: https://doi.org/10.1016/j.ejso.2020.07.025Test
https://api.elsevier.com/content/article/PII:S0748798320306533?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0748798320306533?httpAccept=text/plainTest