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1
المؤلفون: Franco F. Faucher, Kevin J. Liu, Emily D. Cosco, John C. Widen, Jonathan Sorger, Matteo Guerra, Matthew Bogyo
المصدر: ACS Central Science. 9:1059-1069
مصطلحات موضوعية: General Chemical Engineering, General Chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c78e339ee40296814aaf5a9de35b9e4aTest
https://doi.org/10.1021/acscentsci.3c00261Test -
2دورية أكاديمية
المؤلفون: Kas Steuten (10104396), Heeyoung Kim (1987528), John C. Widen (1951051), Brett M. Babin (6184565), Ouma Onguka (10104399), Scott Lovell (122251), Oguz Bolgi (10104402), Berati Cerikan (6685166), Christopher J. Neufeldt (10104405), Mirko Cortese (296117), Ryan K. Muir (6551948), John M. Bennett (9217343), Ruth Geiss-Friedlander (6939698), Christoph Peters (207751), Ralf Bartenschlager (32666), Matthew Bogyo (178300)
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Immunology, Cancer, Mental Health, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, TMPRSS, host cell cysteine cathepsins, target cysteine proteases, drug development programs, transmembrane serine protease, PL, SARS-CoV -2 protease inhibitors, COVID, SARS-CoV -2 virus, compound, entry pathway
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3
المؤلفون: Luca Abdel Ghani, Maria V. Yusenko, Daria Frank, Ramkumar Moorthy, John C. Widen, Wolfgang Dörner, Cyrus Khandanpour, Daniel A. Harki, Karl-Heinz Klempnauer
المصدر: Cancer Letters. 530:170-180
مصطلحات موضوعية: Transcriptional Activation, Cancer Research, THP-1 Cells, CCAAT-Enhancer-Binding Protein-beta, Cell Differentiation, HL-60 Cells, 3T3 Cells, Ligands, Cell Line, Mice, Inbred C57BL, Leukemia, Myeloid, Acute, Mice, Sesquiterpenes, Guaiane, HEK293 Cells, Gene Expression Regulation, Oncology, Cell Line, Tumor, Animals, Humans, Promoter Regions, Genetic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33016526348415d1937cd3d9653200e3Test
https://doi.org/10.1016/j.canlet.2022.01.024Test -
4
المؤلفون: Christopher M. Richards, Sabrina Jabs, Wenjie Qiao, Lauren D. Varanese, Michaela Schweizer, Peter R. Mosen, Nicholas M. Riley, Malte Klüssendorf, James R. Zengel, Ryan A. Flynn, Arjun Rustagi, John C. Widen, Christine E. Peters, Yaw Shin Ooi, Xuping Xie, Pei-Yong Shi, Ralf Bartenschlager, Andreas S. Puschnik, Matthew Bogyo, Carolyn R. Bertozzi, Catherine A. Blish, Dominic Winter, Claude M. Nagamine, Thomas Braulke, Jan E. Carette
المصدر: Science
مصطلحات موضوعية: Mice, Knockout, Mice, Multidisciplinary, Mucolipidoses, Animals, COVID-19, Humans, Proteins, Transferases (Other Substituted Phosphate Groups), Lysosomes, Cathepsins, Mannose, Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbae00bce6adef337f697a05856b2adTest
https://doi.org/10.1126/science.abn5648Test -
5
المؤلفون: Matthew E. Cuellar, Daniel P Dempe, Kay M. Brummond, Paul A. Jackson, John C. Widen, Katherine F. M. Jones, Michael A. Walters, Henry A M Schares, Francois Grillet, Daniel A. Harki
المصدر: J Med Chem
مصطلحات موضوعية: Lactams, Cysteamine, Proof of Concept Study, 01 natural sciences, Article, Sesquiterpenes, Guaiane, 03 medical and health sciences, chemistry.chemical_compound, Chlorocebus aethiops, Drug Discovery, Animals, Humans, Molecule, Reactivity (chemistry), Methylene, Cytotoxicity, Vero Cells, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, NF-kappa B, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HEK293 Cells, chemistry, A549 Cells, Electrophile, Thiol, Lactam, Molecular Medicine, Lactone, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8068a1bbd168bb116fba4b4339fc5e39Test
https://doi.org/10.1021/acs.jmedchem.0c01464Test -
6
المؤلفون: Martina Tholen, John C. Widen, Kerriann M. Casey, Joshua J. Yim, Alwin Klaassen, Jonathan M. Sorger, Stephan Rogalla, Matthew Bogyo, Alexander L. Antaris
المصدر: Nature biomedical engineering
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Lung Neoplasms, Optical contrast, Disease detection, media_common.quotation_subject, Biomedical Engineering, Normal tissue, Contrast Media, Medicine (miscellaneous), Mammary Neoplasms, Animal, Bioengineering, Article, Fluorescence, Cell Line, Mice, 03 medical and health sciences, Tumour tissue, 0302 clinical medicine, Text mining, Animals, Medicine, Contrast (vision), Robotic surgery, Fluorescent Dyes, media_common, Mice, Inbred BALB C, business.industry, Optical Imaging, Computer Science Applications, Surgery, Disease Models, Animal, RAW 264.7 Cells, 030104 developmental biology, Surgery, Computer-Assisted, Female, business, 030217 neurology & neurosurgery, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c86ad00eb6f7fb5952d99cff381006aTest
https://doi.org/10.1038/s41551-020-00616-6Test -
7
المؤلفون: John C. Widen, Ruth Geiss-Friedlander, Berati Cerikan, Matthew Bogyo, Scott Lovell, Heeyoung Kim, Kas Steuten, Ryan K Muir, Ralf Bartenschlager, John M. Bennett, Brett M. Babin, Christoph Peters, Mirko Cortese, Christopher J. Neufeldt, Oguz Bolgi, Ouma Onguka
المساهمون: Steuten, K., Kim, H., Widen, J. C., Babin, B. M., Onguka, O., Lovell, S., Bolgi, O., Cerikan, B., Neufeldt, C. J., Cortese, M., Muir, R. K., Bennett, J. M., Geiss-Friedlander, R., Peters, C., Bartenschlager, R., Bogyo, M.
المصدر: ACS Infectious Diseases
مصطلحات موضوعية: 0301 basic medicine, Proteases, medicine.medical_treatment, 030106 microbiology, papain-like protease, Antiviral Agents, TMPRSS2, Article, Cathepsin L, 03 medical and health sciences, Viral entry, medicine, Humans, Protease Inhibitors, Cathepsin, Serine protease, Protease, biology, Chemistry, SARS-CoV-2, COVID-19, 030104 developmental biology, Infectious Diseases, Drug development, Viral replication, Biochemistry, main protease, biology.protein, cathepsin cross-reactivity, viral entry, Peptide Hydrolases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fb6b93eff1b1816897bfc961c285f8Test
https://hdl.handle.net/11591/487230Test -
8
المؤلفون: John C, Widen, Martina, Tholen, Joshua J, Yim, Matthew, Bogyo
المصدر: Methods in enzymology. 639
مصطلحات موضوعية: Mice, Neoplasms, Animals, Contrast Media, Fluorescent Dyes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::a67a04a3be422d7fca707a42d8f86eaaTest
https://pubmed.ncbi.nlm.nih.gov/32475399Test -
9
المؤلفون: John C. Widen, Matthew Bogyo, Joshua J. Yim, Martina Tholen
مصطلحات موضوعية: 0303 health sciences, Fluorescence-lifetime imaging microscopy, Optical contrast, Chemistry, media_common.quotation_subject, 030303 biophysics, Near-infrared spectroscopy, Signal, Fluorescence, 03 medical and health sciences, In vivo, Biophysics, Contrast (vision), Signal intensity, media_common
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3dc1d70a6cc6332e1c644006c8e091fcTest
https://doi.org/10.1016/bs.mie.2020.04.012Test -
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المؤلفون: Jordan A. Naumann, Daniel A. Harki, Peter M. Gordon, Maryam Ebadi, Jian Tang, Leslie M. Jonart, John C. Widen, David Gordon
المصدر: Bioconjug Chem
مصطلحات موضوعية: 0301 basic medicine, Cell, Biomedical Engineering, Metal Nanoparticles, Pharmaceutical Science, Antineoplastic Agents, Bioengineering, Sarcoma, Ewing, In Vitro Techniques, Irinotecan, Article, 03 medical and health sciences, 0302 clinical medicine, In vivo, Cell Line, Tumor, medicine, Humans, RNA, Messenger, Pharmacology, Chemistry, Organic Chemistry, medicine.disease, In vitro, 030104 developmental biology, medicine.anatomical_structure, Cell culture, Colloidal gold, 030220 oncology & carcinogenesis, Drug delivery, Cancer cell, Cancer research, Gold, Sarcoma, Drug Screening Assays, Antitumor, Topoisomerase I Inhibitors, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894b090089c3b2e4526b023d06dfff8bTest
https://doi.org/10.1021/acs.bioconjchem.7b00774Test