المؤلفون: Silvia T. Erni, John C. Gill, Carlotta Palaferri, Gabriella Fernandes, Michelle Buri, Katherine Lazarides, Denis Grandgirard, Albert S. B. Edge, Stephen L. Leib, Marta Roccio

المصدر: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

مصطلحات موضوعية: drug therapy, sensorineural hearing loss, cochlear organoids, hair cell regeneration, Notch signaling, gamma secretase inhibitor, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fcell.2021.710159/fullTest; https://doaj.org/toc/2296-634XTest

الوصول الحر: https://doaj.org/article/a5657b29045d44028d45c274ad89c520Test

المؤلفون: Silvia T. Erni, John C. Gill, Carlotta Palaferri, Gabriella Fernandes, Michelle Buri, Katherine Lazarides, Denis Grandgirard, Albert S. B. Edge, Stephen L. Leib, Marta Roccio

المساهمون: University of Zurich, Roccio, Marta

المصدر: Erni, Silvia T.; Gill, John C.; Palaferri, Carlotta; Fernandes, Gabriella; Buri, Michelle; Lazarides, Katherine; Grandgirard, Denis; Edge, Albert S. B.; Leib, Stephen; Roccio, Marta (2021). Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors. Frontiers in cell and developmental biology, 9(2256) Frontiers 10.3389/fcell.2021.710159 <http://dx.doi.org/10.3389/fcell.2021.710159Test>
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)

مصطلحات موضوعية: QH301-705.5, gamma secretase inhibitor, Notch signaling pathway, 10045 Clinic for Otorhinolaryngology, 610 Medicine & health, Biology, sensorineural hearing loss, 1309 Developmental Biology, 1307 Cell Biology, Cell and Developmental Biology, cochlear organoids, medicine, otorhinolaryngologic diseases, Biology (General), Cochlea, Notch signaling, Original Research, Round window, Transdifferentiation, Cell Biology, medicine.disease, Cell biology, drug therapy, medicine.anatomical_structure, Organ of Corti, Cell culture, 570 Life sciences, biology, Sensorineural hearing loss, Hair cell, sense organs, 610 Medizin und Gesundheit, hair cell regeneration, 570 Biowissenschaften, Biologie, Developmental Biology

وصف الملف: application/pdf; fcell-09-710159.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d6deeafd3eaf59a98fafb2632610c5Test
https://boris.unibe.ch/158164/1/fcell-09-710159.pdfTest

المؤلفون: Silvia T. Erni, John C. Gill, Carlotta Palaferri, Gabriella Fernandes, Michelle Buri, Katherine Lazarides, Denis Grandgirard, Albert S. B. Edge, Stephen L. Leib, Marta Roccio

مصطلحات موضوعية: Cell Biology, Marine Biology, Cell Development, Proliferation and Death, Cell Metabolism, Cell Neurochemistry, Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), drug therapy, sensorineural hearing loss, cochlear organoids, hair cell regeneration, Notch signaling, gamma secretase inhibitor

العلاقة: https://figshare.com/articles/dataset/Data_Sheet_1_Hair_Cell_Generation_in_Cochlear_Culture_Models_Mediated_by_Novel_-Secretase_Inhibitors_PDF/15163044Test

الإتاحة: https://doi.org/10.3389/fcell.2021.710159.s001Test
https://figshare.com/articles/dataset/Data_Sheet_1_Hair_Cell_Generation_in_Cochlear_Culture_Models_Mediated_by_Novel_-Secretase_Inhibitors_PDF/15163044Test

المؤلفون: John C Gill, Oulu Wang, Shelley Kakar, Enzo Martinelli, Rona S Carroll, Ursula B Kaiser

المصدر: PLoS ONE, Vol 5, Iss 7, p e11911 (2010)

مصطلحات موضوعية: Medicine, Science

العلاقة: http://europepmc.org/articles/PMC2912854?pdf=renderTest; https://doaj.org/toc/1932-6203Test; https://doaj.org/article/86c9b65e6d1948729d898ebccb1c1560Test

الإتاحة: https://doi.org/10.1371/journal.pone.0011911Test
https://doaj.org/article/86c9b65e6d1948729d898ebccb1c1560Test

المؤلفون: Andrew Wolfe, John C. Gill, Caroline A Maguire, Ursula B. Kaiser, Víctor M. Navarro, Serap Simavli, Rona S. Carroll, Iain R. Thompson

المصدر: Endocrinology. 156:2313-2322

مصطلحات موضوعية: 0301 basic medicine, puberty, 5 aminovalerylsubstance P [7-11][9 proline 10 (n methylleucine)], neurokinin 1 receptor, substance P, Substance P, Stimulation, neurokinin 1 receptor agonist, Mice, chemistry.chemical_compound, analogs and derivatives, 0302 clinical medicine, Endocrinology, prepuberty, arcuate nucleus, Sexual maturity, animal, genetics, nociception, Sexual Maturation, Receptor, Original Research, fertility, adult, Receptors, Neurokinin-1, delayed puberty, postnatal development, metastin, female, priority journal, real time polymerase chain reaction, medicine.symptom, Gonadotropin, hormones, hormone substitutes, and hormone antagonists, Delayed puberty, endocrine system, medicine.medical_specialty, gonadotropin release, phenotype, regulatory mechanism, medicine.drug_class, animal experiment, Neuropeptide, 030209 endocrinology & metabolism, Biology, Article, corpus luteum, reverse transcription polymerase chain reaction, 03 medical and health sciences, follitropin release, Internal medicine, Tachykinin receptor 1, medicine, Animals, controlled study, gonadotropin, mouse, nonhuman, mediobasal hypothalamus, animal model, female subfertility, Peptide Fragments, 030104 developmental biology, chemistry, gonadorelin, peptide fragment, drug effects, agonists, litter size, female fertility, metabolism, Gonadotropins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96eb78440ca2d6905d83abb81d876b29Test
https://doi.org/10.1210/en.2014-2012Test

المؤلفون: Francis de Zegher, Ursula B. Kaiser, Víctor M. Navarro, Joel N. Hirschhorn, Vinicius Nahime Brito, Berenice B. Mendonca, Delanie B. Macedo, Rona S. Carroll, Sekoni D. Noel, Priscilla Cukier, Priscila Gagliardi, Cristiane Kochi, Ana Claudia Latronico, Tânia Rodrigues, Andrew Dauber, Dominique Beckers, Iain R. Thompson, Ana Paula Abreu, John C. Gill, Luciana Ribeiro Montenegro, Carlos Alberto Longui

المصدر: New England Journal of Medicine. 368:2467-2475

مصطلحات موضوعية: Male, Heterozygote, medicine.medical_specialty, Ubiquitin-Protein Ligases, Hypothalamus, Mutation, Missense, Puberty, Precocious, Biology, Article, Frameshift mutation, Mice, symbols.namesake, Internal medicine, medicine, Animals, Humans, Precocious puberty, Missense mutation, Exome, RNA, Messenger, Child, Frameshift Mutation, Gene, Genetic Association Studies, Sanger sequencing, Genetics, Arcuate Nucleus of Hypothalamus, Heterozygote advantage, Sequence Analysis, DNA, General Medicine, medicine.disease, Pedigree, Endocrinology, Ribonucleoproteins, Child, Preschool, symbols, Female, Genomic imprinting

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d7f7218cea3c9dc99f945fd9c0b159Test
https://doi.org/10.1056/nejmoa1302160Test

المؤلفون: Pei-San Tsai, John C. Gill

المصدر: Biology of Reproduction. 74:463-472

مصطلحات موضوعية: medicine.medical_specialty, Neurite, Axon extension, Cell Biology, General Medicine, Gonadotropin-releasing hormone, Biology, Fibroblast growth factor, Cell biology, medicine.anatomical_structure, Endocrinology, nervous system, Reproductive Medicine, Fibroblast growth factor receptor, Median eminence, Internal medicine, medicine, Axon guidance, Axon

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ffd707933c5c42c9bedc90508b421675Test
https://doi.org/10.1095/biolreprod.105.046904Test

المؤلفون: Mohammed El Majdoubi, Richard I. Weiner, Sabine Werner, Hector Postigo, Suzanne M. Moenter, Toni R. Pak, Pei-San Tsai, Sreenivasan Paruthiyil, John C. Gill

المصدر: Molecular Endocrinology. 19:225-236

مصطلحات موضوعية: endocrine system, medicine.medical_specialty, DNA, Complementary, Neurite, Cell Survival, Cell Count, Mice, Transgenic, Gonadotropin-releasing hormone, Transfection, Fibroblast growth factor, Cell Line, Gonadotropin-Releasing Hormone, Mice, Reproductive senescence, Prosencephalon, Endocrinology, Internal medicine, medicine, Animals, Transgenes, Receptor, Molecular Biology, Neurons, GnRH Neuron, biology, General Medicine, Receptors, Fibroblast Growth Factor, Pedigree, Fibroblast Growth Factors, Phenotype, biology.protein, Signal transduction, hormones, hormone substitutes, and hormone antagonists, Neurotrophin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d30a5d71fc9230ff7da2b96511f8b44Test
https://doi.org/10.1210/me.2004-0330Test

المؤلفون: John C. Gill, Pei-San Tsai

المساهمون: John C. Gill, Pei-San Tsai

المصدر: https://doi.org/10.1095/biolreprod.105.046904Test.

جغرافية الموضوع: world

وصف الملف: text/HTML

الإتاحة: https://doi.org/10.1095/biolreprod.105.046904Test

المؤلفون: John C. Gill, Ursula B. Kaiser, Shuyun Xu, Cecilia Martin, Cecilia Kwong, Víctor M. Navarro, Rona S. Carroll, Donald K. Clifton, Sekoni D. Noel, Robert A. Steiner

المصدر: Endocrinology. 153(10)

مصطلحات موضوعية: medicine.medical_specialty, medicine.drug_class, Neurokinin B, Gonadotropin-releasing hormone, Biology, Gonadotropin-Releasing Hormone, chemistry.chemical_compound, Mice, Endocrinology, Kisspeptin, Internal medicine, Tachykinins, medicine, Animals, Sexual Maturation, Protein Precursors, Receptor, Feedback, Physiological, Mice, Knockout, Neurons, Kisspeptins, Arc (protein), Estradiol, Antagonist, Arcuate Nucleus of Hypothalamus, Neuroendocrinology, Luteinizing Hormone, chemistry, Sex steroid, Estrogen, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b247b71c2704ed6a40ad0a76e703ef3Test
https://pubmed.ncbi.nlm.nih.gov/22893725Test