المؤلفون: Giulia Callegaro, Johannes P. Schimming, Janet Piñero González, Steven J. Kunnen, Lukas Wijaya, Panuwat Trairatphisan, Linda van den Berk, Kim Beetsma, Laura I. Furlong, Jeffrey J. Sutherland, Jennifer Mollon, James L. Stevens, Bob van de Water

المصدر: iScience, Vol 26, Iss 3, Pp 106094- (2023)

مصطلحات موضوعية: Gene network, Bioinformatics, Transcriptomics, Science

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2589004223001712Test; https://doaj.org/toc/2589-0042Test

الوصول الحر: https://doaj.org/article/c1ec17ac979040d09bc96f5bae7f9e91Test

المؤلفون: Erika Moro, Johannes P Schimming, José V. Castell, Bas ter Braak, Laia Tolosa, Barbara M.A. van Vugt-Lussenburg, Bob van der Water, Teresa Martínez-Sena, Miguel A. Miranda, Sylvia Escher

المساهمون: Publica

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Archives of Toxicology, 95(6), 2109-2121. Springer Science and Business Media LLC
ARCHIVES OF TOXICOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Archives of Toxicology

مصطلحات موضوعية: Redox-cycling phenols, Plastic seals, 0301 basic medicine, Cytotox CALUX reporter gene assay, Health, Toxicology and Mutagenesis, Diffusion, HepG2 BAC-GFP SRXN1 assay, 010501 environmental sciences, Toxicology, 01 natural sciences, Gas Chromatography-Mass Spectrometry, 03 medical and health sciences, chemistry.chemical_compound, Phenols, Cross-contamination of culture wells, Cell Line, Tumor, Humans, Incubation, 0105 earth and related environmental sciences, Nrf2 CALUX reporter gene assay, Hepatotoxicity, Reproducibility of Results, Hep G2 Cells, General Medicine, In vitro toxicity, In vitro, High-Throughput Screening Assays, Hydroquinones, Quinone, In Vitro Systems, 030104 developmental biology, chemistry, Environmental chemistry, Toxicity, Degradation (geology), Oxidation-Reduction, Redox cycling, Toxicity of phenols, High-content imaging

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b272012eddeb7cdefeccbea6af2290Test
https://doi.org/10.1007/s00204-021-03036-wTest

المؤلفون: Paul Jennings, Giada Carta, Johannes P Schimming, Erik H.J. Danen, Marcel Leist, Giulia Callegaro, Nanette G Vrijenhoek, Joost B. Beltman, Anna Forsby, Johannes Delp, Andrew White, Bob van de Water, Sylvia E. Le Dévédec, Huan Yang, Wanda van der Stel, Salihanur Darici

المساهمون: Molecular and Computational Toxicology, AIMMS

المصدر: van der Stel, W, Yang, H, Vrijenhoek, N G, Schimming, J P, Callegaro, G, Carta, G, Darici, S, Delp, J, Forsby, A, White, A, le Dévédec, S, Leist, M, Jennings, P, Beltman, J B, van de Water, B & Danen, E H J 2022, ' Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation ', Archives of Toxicology, vol. 96, no. 1, pp. 259-285 . https://doi.org/10.1007/s00204-021-03160-7Test
Archives of Toxicology, 96
Archives of Toxicology
Archives of Toxicology, 96(1), 259-285. Springer Verlag

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Mitochondrial toxicity, ETC complex inhibitors, High-content imaging, TempO-Seq, DILI, Oxidative phosphorylation, Toxicology, ETC Complex Inhibitors, Electron Transport, ddc:570, medicine, Gene silencing, Humans, Glycolysis, Viability assay, Electron Transport Complex I, Mitochondrial toxicity, Chemistry, Endoplasmic reticulum, Mitochondrial Toxicity, ETC complex inhibitors, General Medicine, Hep G2 Cells, medicine.disease, Cell biology, Mitochondria, In Vitro Systems, medicine.anatomical_structure, High-Content Imaging, Hepatocyte, Unfolded protein response, Hepatocytes, TempO-Seq, DILI, High-content imaging

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e5ec3b4fb4c6608dfe265e2934a630Test
https://hdl.handle.net/1871.1/e0b19077-5a27-48fb-bc1b-0dc3bbb415f8Test

المؤلفون: Anja Wilmes, Tobias Strassfeld, Harry Vrieling, Manoj Kumar, Balázs Mihalik, Costanza Rovida, Giorgia Pallocca, Nanette G Vrijenhoek, Ciarán Fisher, Bart van der Burg, Thomas Braunbeck, Xenia Dolde, Alice Krebs, Zofia Janstova, Béla Z. Schmidt, Wiebke Albrecht, Jan G. Hengstler, Tim Brecklinghaus, David A. Fluri, J. J. W. A. Boei, Thomas Exner, Marcel Leist, Tanja Waldmann, Jaffar Kisitu, Anna-Katharina Holzer, Manuel Pastor, Joh Dokler, Andrea Paola Cediel Ulloa, Paul Jennings, Barbara M.A. van Vugt-Lussenburg, Bas ter Braak, Bob van de Water, Anna Forsby, Maja Brajnik, Wolfgang Moritz, Catherine M. Verfaillie, Johannes P Schimming, Rebecca von Hellfeld, Alice Limonciel, Francois Busquet, Julianna Kobolák, Ugis Sarkans, Regina Stöber, Jessica Lundqvist, Andras Dinnyes

المساهمون: Molecular and Computational Toxicology, AIMMS

المصدر: Archives of Toxicology
Archives of Toxicology, 94(7), 2435-2461. Springer Verlag
Archives of Toxicology, 94(7), 2435-2461. SPRINGER HEIDELBERG
Krebs, A, van Vugt-Lussenburg, B M A, Waldmann, T, Albrecht, W, Boei, J, Ter Braak, B, Brajnik, M, Braunbeck, T, Brecklinghaus, T, Busquet, F, Dinnyes, A, Dokler, J, Dolde, X, Exner, T E, Fisher, C, Fluri, D, Forsby, A, Hengstler, J G, Holzer, A-K, Janstova, Z, Jennings, P, Kisitu, J, Kobolak, J, Kumar, M, Limonciel, A, Lundqvist, J, Mihalik, B, Moritz, W, Pallocca, G, Ulloa, A P C, Pastor, M, Rovida, C, Sarkans, U, Schimming, J P, Schmidt, B Z, Stöber, R, Strassfeld, T, van de Water, B, Wilmes, A, van der Burg, B, Verfaillie, C M, von Hellfeld, R, Vrieling, H, Vrijenhoek, N G & Leist, M 2020, ' The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods ', Archives of Toxicology, vol. 94, no. 7, pp. 2435-2461 . https://doi.org/10.1007/s00204-020-02802-6Test
Archives of Toxicology, 94(7), 2435-2461
Archives of toxicology, 94:2435-2461

مصطلحات موضوعية: 0301 basic medicine, Test data generation, Computer science, Health, Toxicology and Mutagenesis, Data validation, HAZARD ASSESSMENT, Toxicology, CELL-CULTURE PRACTICE, Documentation, Policy Making, Cells, Cultured, Zebrafish, media_common, EPITHELIAL-CELLS, General Medicine, data processing, GIVIMP, in vitro toxicology, metadata, nuclear receptor, Test (assessment), Strategy implementation, Europe, Data processing, In Vitro Systems, NEURAL CREST MIGRATION, Life Sciences & Biomedicine, REPRODUCTIVE TOXICITY, Risk Assessment, 03 medical and health sciences, SDG 17 - Partnerships for the Goals, ddc:570, Terminology as Topic, Toxicity Tests, media_common.cataloged_instance, Animals, Humans, European union, Retrospective Studies, In vitro toxicology, Electronic Data Processing, Metadata, Science & Technology, business.industry, 030111 toxicology, Reproducibility of Results, CALUX METHOD, IN-VITRO, Pipeline (software), DRUG DISCOVERY, 030104 developmental biology, Nuclear receptor, DEVELOPMENTAL NEUROTOXICITY DNT, Government Regulation, Software engineering, business, EMBRYONIC STEM-CELLS

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e81d40cbe9c93d9b654557d3afcabeTest
https://hdl.handle.net/1887/3184413Test

المؤلفون: Johannes P Schimming, Jeffrey J. Sutherland, Giulia Callegaro, James L. Stevens, B. van de Water, Lukas S Wijaya, Steven J. Kunnen

المصدر: Toxicology Letters. 350:S228

مصطلحات موضوعية: In vivo, Rat liver, General Medicine, Biology, Toxicology, In vitro, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2f59b9568f94057a0cedf890e3955da3Test
https://doi.org/10.1016/s0378-4274Test(21)00771-2

المؤلفون: Johannes P, Schimming, Bas, Ter Braak, Marije, Niemeijer, Steven, Wink, Bob, van de Water

المصدر: Methods in molecular biology (Clifton, N.J.). 1981

مصطلحات موضوعية: Microscopy, Cholestasis, Microscopy, Fluorescence, Hepatocytes, Humans, Hep G2 Cells, Chemical and Drug Induced Liver Injury, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::191a32d0e84afa575cee5f745caac832Test
https://pubmed.ncbi.nlm.nih.gov/31016656Test

المؤلفون: Bob van de Water, Bas ter Braak, Johannes P Schimming, Marije Niemeijer, Steven Wink

المصدر: Methods in Molecular Biology
Methods in Molecular Biology-Experimental Cholestasis Research
Methods in Molecular Biology ISBN: 9781493994199

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Gene knockdown, medicine.medical_treatment, Oxidative phosphorylation, Biology, medicine.disease, medicine.disease_cause, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cytokine, Cholestasis, Live cell imaging, 030220 oncology & carcinogenesis, Cellular stress response, medicine, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2ea39f0fc4cb2516ba5cf7211ba536Test

المؤلفون: Joost B. Beltman, Jan P. Langenberg, Johannes P Schimming, Luc J M Bischoff, Bob van de Water, Isoude A. Kuijper, Bas ter Braak, Daan Noort, Liesanne Wolters

المساهمون: TNO Defensie en Veiligheid

المصدر: Archives of Toxicology
Archives of Toxicology, 93(2), 435-451

مصطلحات موضوعية: 0301 basic medicine, Health, Toxicology and Mutagenesis, Cell, 010501 environmental sciences, medicine.disease_cause, Toxicology, 01 natural sciences, environment and public health, Green fluorescent protein, Soft electrophiles, Oxidoreductases Acting on Sulfur Group Donors, Gene knockdown, TS - Technical Sciences, Kelch-Like ECH-Associated Protein 1, Chemistry, Nuclear Proteins, Hep G2 Cells, General Medicine, respiratory system, Observation, Weapon & Protection Systems, Molecular Imaging, Cell biology, Protein Transport, medicine.anatomical_structure, Toxicity, Single-Cell Analysis, MafG Transcription Factor, HepG2, NF-E2-Related Factor 2, Green Fluorescent Proteins, Srxn1, Defence Research, Context (language use), Defence, Safety and Security, digestive system, Nrf2, Xenobiotics, Repeated exposure, 03 medical and health sciences, Live cell imaging, Toxicity Tests, medicine, Humans, MafF Transcription Factor, 0105 earth and related environmental sciences, Dose-Response Relationship, Drug, Maleates, CBRN - CBRN Protection, Hydroquinones, Repressor Proteins, 030104 developmental biology, Cell culture, Oxidative stress

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3e4229c58ccc0324a67ca859a46d12Test
http://resolver.tudelft.nl/uuid:e3a549dd-28c5-486d-ae29-d8001b12af8fTest

المؤلفون: L.J.M. Bischoff, B. van de Water, Johannes P Schimming, B. ter Braak

المصدر: Toxicology Letters. 295:S126

مصطلحات موضوعية: Liver injury, Biochemistry, Chemistry, medicine, Identification (biology), General Medicine, Toxicology, medicine.disease_cause, medicine.disease, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::383d21eaeadd90c27b8c667ff19bf32aTest
https://doi.org/10.1016/j.toxlet.2018.06.682Test