المؤلفون: Reza Zandi Shafagh, Sonia Youhanna, Jibbe Keulen, Joanne X. Shen, Nayere Taebnia, Lena C. Preiss, Kathrin Klein, Florian A. Büttner, Mikael Bergqvist, Wouter van derWijngaart, Volker M. Lauschke

المصدر: Advanced Science, Vol 9, Iss 34, Pp n/a-n/a (2022)

مصطلحات موضوعية: glycemic control, microfluidic cell culture, microphysiological model, organ‐on‐a‐chip, tissue interaction, Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2198-3844Test

الوصول الحر: https://doaj.org/article/657e83a29fa94ec4aab23e829d3d2254Test

المؤلفون: Joanne X. Shen, Morgane Couchet, Jérémy Dufau, Thais de Castro Barbosa, Maximilian H. Ulbrich, Martin Helmstädter, Aurino M. Kemas, Reza Zandi Shafagh, Marie‐Adeline Marques, Jacob B. Hansen, Niklas Mejhert, Dominique Langin, Mikael Rydén, Volker M. Lauschke

المصدر: Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)

مصطلحات موضوعية: adipose stem cells, fat cells, lipidomics, organotypic cell culture, preadipocytes, stromal vascular fraction, Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2198-3844Test

الوصول الحر: https://doaj.org/article/568a4d59aeaf495091d40d5a6daf16a5Test

المؤلفون: Yitian Zhou, Joanne X. Shen, Volker M. Lauschke

المصدر: Frontiers in Pharmacology, Vol 10 (2019)

مصطلحات موضوعية: hepatotoxicity, 3D cell culture, spheroids, liver-on-a-chip, bioreactors, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fphar.2019.01093/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/99f05ca4d0be468f9bdb69b1b7478847Test

المؤلفون: Justin Stebbing, Ginés Sánchez Nievas, Marco Falcone, Sonia Youhanna, Peter Richardson, Silvia Ottaviani, Joanne X Shen, Christian Sommerauer, Giusy Tiseo, Lorenzo Ghiadoni, Agostino Virdis, Fabio Monzani, Luis Romero Rizos, Francesco Forfori, Almudena Avendaño Céspedes, Salvatore De Marco, Laura Carrozzi, Fabio Lena, Pedro Manuel Sánchez-Jurado, Leonardo Gianluca Lacerenza, Nencioni Cesira, David Caldevilla Bernardo, Antonio Perrella, Laura Niccoli, Lourdes Sáez Méndez, Daniela Matarrese, Delia Goletti, Yee-Joo Tan, Vanessa Monteil, George Dranitsaris, Fabrizio Cantini, Alessio Farcomeni, Shuchismita Dutta, Stephen K Burley, Haibo Zhang, Mauro Pistello, William Li, Marta Mas Romero, Fernando Andrés Pretel, Rafaela Sánchez Simón-Talero, Rafael García-Molina, Claudia Kutter, James H Felce, Zehra F Nizami, Andras G Miklosi, Josef M Penninger, Francesco Menichetti, Ali Mirazimi, Pedro Abizanda, Volker M Lauschke

مصطلحات موضوعية: Medical virology, Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, RHEUMATOID-ARTHRITIS, FUNCTIONAL RECEPTOR, BARICITINIB, PLACEBO, PROTEIN, INJURY, Liver, Humans, Sulfonamides, Azetidines, Pyrazoles, Purines, Cytokines, Enzyme Inhibitors, Antiviral Agents, Proportional Hazards Models, Drug Evaluation, Preclinical, Gene Expression Profiling, Platelet Activation, Adult, Aged, 80 and over, Middle Aged, Italy, Spain

العلاقة: 10779/aru.25379431.v1; https://figshare.com/articles/journal_contribution/JAK_inhibition_reduces_SARS-CoV-2_liver_infectivity_and_modulates_inflammatory_responses_to_reduce_morbidity_and_mortality/25379431Test

الإتاحة: https://figshare.com/articles/journal_contribution/JAK_inhibition_reduces_SARS-CoV-2_liver_infectivity_and_modulates_inflammatory_responses_to_reduce_morbidity_and_mortality/25379431Test

المؤلفون: Elena Griseti, Mikael Rydén, Dominique Langin, Ez-Zoubir Amri, Niklas Mejhert, Etienne Mouisel, Lucas Massier, Joanne X. Shen, Jérémy Dufau, Thais de Castro Barbosa, Morgane Couchet, Volker M. Lauschke

المصدر: Cell Physiology

مصطلحات موضوعية: 0301 basic medicine, Cell physiology, Cell Survival, Physiology, Cellular differentiation, Cell Culture Techniques, Adipose tissue, Cell Communication, Biology, Cell Line, Tissue Culture Techniques, 03 medical and health sciences, Paracrine signalling, chemistry.chemical_compound, 0302 clinical medicine, Species Specificity, Spheroids, Cellular, Lipid droplet, Adipocyte, Adipocytes, Animals, Humans, Adipogenesis, Cell Biology, Cell biology, Phenotype, 030104 developmental biology, Adipose Tissue, chemistry, Cell culture, 030220 oncology & carcinogenesis, Stem cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e0eaf3bd7bfc6cdf846900a08578ecTest
https://doi.org/10.1152/ajpcell.00519.2020Test

المؤلفون: Emelie Barreby, Benedikt Strunz, Valerio Azzimato, Joanne X. Shen, Léa Naudet, Isabella Sönnerborg, André Sulen, Sebastian Nock, Laura Levi, Cecilia Morgantini, Achilleas Fardellas, Helene Johansson, Greg Nowak, Per Stal, Ewa Ellis, Erik Naslund, Volker Lauschke, Niklas Björkström, Ping Chen, Myriam Aouadi

المصدر: Journal of Hepatology. 77:S756-S757

مصطلحات موضوعية: Hepatology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a1d56bbe9ee4a60a56036fc32c005fffTest
https://doi.org/10.1016/s0168-8278Test(22)01829-3

المؤلفون: Valerio Azzimato, Ping Chen, Emelie Barreby, Cecilia Morgantini, Laura Levi, Ana Vankova, Jennifer Jager, André Sulen, Marina Diotallevi, Joanne X. Shen, Ewa Ellis, Mikael Ryden, Erik Naslund, Anders Thorell, Volker Lauschke, Keith M. Channon, Mark J. Crabtree, Arvand Haschemi, Siobhan M. Craige, Mattia Mori, Francesco Spallotta, Myriam Aouadi

المصدر: Journal of Hepatology. 77:S665-S666

مصطلحات موضوعية: Hepatology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::499e918d6e735d01f2ad230cb3337307Test
https://doi.org/10.1016/s0168-8278Test(22)01649-x

المؤلفون: Joanne X. Shen, Tommy Haraldsson, Reza Zandi Shafagh, Weijin Guo, Volker M. Lauschke, Wouter van der Wijngaart, Sonia Youhanna

المصدر: ACS applied bio materials. 3(12)

مصطلحات موضوعية: Materials science, Nanostructure, business.industry, Biochemistry (medical), Biomedical Engineering, Physics::Optics, Nanotechnology, General Chemistry, Human cell, Protein patterning, Nanoimprint lithography, law.invention, Biomaterials, law, Photonics, business, Nanoscopic scale

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3952501e160062e314348220bb9f50d4Test
https://pubmed.ncbi.nlm.nih.gov/35019647Test

المؤلفون: George Dranitsaris, Silvia Ottaviani, Rafael García-Molina, Luis Romero Rizos, Antonio Perrella, Christian Sommerauer, Alessio Farcomeni, David Caldevilla Bernardo, Zehra F. Nizami, Agostino Virdis, Nencioni Cesira, James H. Felce, Pedro Manuel Sánchez-Jurado, Almudena Avendaño Céspedes, Marta Mas Romero, Fernando Andrés Pretel, Peter D. Richardson, Shuchismita Dutta, Yee-Joo Tan, Laura Niccoli, Leonardo Gianluca Lacerenza, Haibo Zhang, Claudia Kutter, Delia Goletti, Stephen K. Burley, Ali Mirazimi, Fabio Lena, Daniela Matarrese, Giusy Tiseo, Francesco Forfori, Salvatore De Marco, Andras G. Miklosi, Volker M. Lauschke, Justin Stebbing, Joanne X. Shen, Lourdes Sáez Méndez, Fabrizio Cantini, Mauro Pistello, Fabio Monzani, Josef M. Penninger, Lorenzo Ghiadoni, Rafaela Sánchez Simón-Talero, Sonia Youhanna, Vanessa Monteil, Francesco Menichetti, Laura Carrozzi, William W. Li, Marco Falcone, Pedro Abizanda, Ginés Sánchez Nievas

المساهمون: National Institute for Health Research, Imperial College Healthcare NHS Trust- BRC Funding

المصدر: Science Advances

مصطلحات موضوعية: Male, BARICITINIB, viruses, Drug Evaluation, Preclinical, PROTEIN, 0302 clinical medicine, FUNCTIONAL RECEPTOR, Medicine, RNA-Seq, Enzyme Inhibitors, skin and connective tissue diseases, Research Articles, Infectivity, Aged, 80 and over, 0303 health sciences, Sulfonamides, Multidisciplinary, PLACEBO, SciAdv r-articles, Middle Aged, 3. Good health, Multidisciplinary Sciences, Cytokine release syndrome, Italy, Liver, 030220 oncology & carcinogenesis, Science & Technology - Other Topics, Cytokines, Female, Patient Safety, Cytokine Release Syndrome, Viral load, Research Article, Adult, Interferon alpha-2, Antiviral Agents, 03 medical and health sciences, Viral entry, INJURY, Humans, Platelet activation, 030304 developmental biology, Aged, Janus Kinases, Proportional Hazards Models, Science & Technology, business.industry, SARS-CoV-2, Gene Expression Profiling, fungi, COVID-19, Virus Internalization, medicine.disease, Platelet Activation, RHEUMATOID-ARTHRITIS, respiratory tract diseases, COVID-19 Drug Treatment, body regions, Coronavirus, Pneumonia, Purines, Spain, Immunology, Azetidines, Pyrazoles, business, Cytokine storm, Janus kinase, Settore SECS-S/01

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ea85c628738708305780378eed2aa6Test
http://hdl.handle.net/11568/1059182Test

المؤلفون: Sonia Youhanna, Aurino M. Kemas, Lena Preiss, Yitian Zhou, Joanne X. Shen, Selgin D. Cakal, Francesco S. Paqualini, Sravan K. Goparaju, Reza Zandi Shafagh, Johan Ulrik Lind, Carl M. Sellgren, Volker M. Lauschke

المصدر: Youhanna, S, Kemas, A M, Preiss, L, Zhou, Y, Shen, J X, Cakal, S D, Paqualini, F S, Goparaju, S K, Shafagh, R Z, Lind, J U, Sellgren, C M & Lauschke, V M 2022, ' Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development-Current State-of-the-Art and Future Perspectives ', Pharmacological Reviews, vol. 74, no. 1, pp. 141-206 . https://doi.org/10.1124/pharmrev.120.000238Test

مصطلحات موضوعية: Pharmacology, Drug Development, Drug-Related Side Effects and Adverse Reactions, Drug Discovery, Drug Evaluation, Preclinical, Molecular Medicine, Humans, Multicenter Studies as Topic

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684d7b7287c0191ed8678b77b82ef2c4Test
https://pubmed.ncbi.nlm.nih.gov/35017176Test