المؤلفون: Jessica K. Nelson, May Zaw Thin, Theodore Evan, Steven Howell, Mary Wu, Bruna Almeida, Nathalie Legrave, Duco S. Koenis, Gabriela Koifman, Yoichiro Sugimoto, Miriam Llorian Sopena, James MacRae, Emma Nye, Michael Howell, Ambrosius P. Snijders, Andreas Prachalias, Yoh Zen, Debashis Sarker, Axel Behrens

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/cd8dab384b2a46bf9a9f3d5ce3b2663fTest

المؤلفون: Omar M. Khan, Jorge Almagro, Jessica K. Nelson, Stuart Horswell, Vesela Encheva, Kripa S. Keyan, Bruce E. Clurman, Ambrosius P. Snijders, Axel Behrens

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/6e27448b8929476da30da600acc41eb2Test

المؤلفون: Vincenzo Sorrentino, Jessica K. Nelson, Elena Maspero, André R.A. Marques, Lilith Scheer, Simona Polo, Noam Zelcer

المصدر: Journal of Lipid Research, Vol 54, Iss 8, Pp 2174-2184 (2013)

مصطلحات موضوعية: liver X receptor, low density lipoprotein receptor, inducible degrader of low density lipoprotein receptor, E3-ubiquitin ligase, endocytosis, lipoprotein receptors, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520375337Test; https://doaj.org/toc/0022-2275Test

الوصول الحر: https://doaj.org/article/695bff5da0664a00b1b31b5753bab0edTest

المؤلفون: Kripa S. Keyan, Jorge Almagro, Bruce E. Clurman, Ambrosius P. Snijders, Stuart Horswell, Vesela Encheva, Jessica K. Nelson, Axel Behrens, Omar M. Khan

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, F-Box-WD Repeat-Containing Protein 7, Ubiquitylation, General Physics and Astronomy, Plasma protein binding, Substrate Specificity, law.invention, Small hairpin RNA, 0302 clinical medicine, Ubiquitin, law, MCL1, RNA, Small Interfering, Multidisciplinary, biology, Protein Stability, Chemistry, 3. Good health, Ubiquitin ligase, Cell biology, Cancer therapeutic resistance, 030220 oncology & carcinogenesis, Protein Binding, Proteasome Endopeptidase Complex, Ubiquitin-Protein Ligases, Science, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Humans, Mass spectrometry, Lysine, HEK 293 cells, Ubiquitination, General Chemistry, HCT116 Cells, HEK293 Cells, 030104 developmental biology, Drug Resistance, Neoplasm, Ubiquitin ligases, Proteolysis, Ubiquitin-Conjugating Enzymes, Cancer cell, Biocatalysis, biology.protein, Myeloid Cell Leukemia Sequence 1 Protein, Suppressor, Carrier Proteins, Protein Processing, Post-Translational

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52317b9d43255e960ff3720013d3922fTest
https://doaj.org/article/6e27448b8929476da30da600acc41eb2Test

المؤلفون: Emma C L Cook, Jessica K Nelson, Vincenzo Sorrentino, Duco Koenis, Martina Moeton, Saskia Scheij, Roelof Ottenhoff, Boris Bleijlevens, Anke Loregger, Noam Zelcer

المصدر: PLoS ONE, Vol 12, Iss 2, p e0172721 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC5322959?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/ace271f92020402192c273dfc41da462Test

المؤلفون: Jessica K. Nelson, May Zaw Thin, Theodore Evan, Steven Howell, Mary Wu, Bruna Almeida, Nathalie Legrave, Duco S. Koenis, Gabriela Koifman, Yoichiro Sugimoto, Miriam Llorian Sopena, James MacRae, Emma Nye, Michael Howell, Ambrosius P. Snijders, Andreas Prachalias, Yoh Zen, Debashis Sarker, Axel Behrens

المصدر: Nature communications. 13(1)

مصطلحات موضوعية: Model organisms, endocrine system diseases, Immunology, General Physics and Astronomy, Gene Expression, Infectious Disease, Biochemistry & Proteomics, General Biochemistry, Genetics and Molecular Biology, Signalling & Oncogenes, Mice, Cell Line, Tumor, Tumor Microenvironment, Animals, Humans, Computational & Systems Biology, Chemical Biology & High Throughput, Human Biology & Physiology, Multidisciplinary, Stem Cells, FOS: Clinical medicine, Genome Integrity & Repair, General Chemistry, Cell Biology, Tumour Biology, digestive system diseases, Pancreatic Neoplasms, Metabolism, Cardiovascular and Metabolic Diseases, Genetics & Genomics, Glycolysis, Ubiquitin Thiolesterase, Developmental Biology, Carcinoma, Pancreatic Ductal

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854e2c25058cbc76694ffc7ae82331fcTest
https://pubmed.ncbi.nlm.nih.gov/35440539Test

المؤلفون: Jessica K. Nelson, Nienke M. van Loon, Noam Zelcer, Martina Moeton, Suzanne A.E. van Wouw, Roelof Ottenhoff, Saskia Scheij, Jenina Kingma

المساهمون: Medical Biochemistry, ACS - Atherosclerosis & ischemic syndromes, ACS - Diabetes & metabolism, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, ACS - Amsterdam Cardiovascular Sciences

المصدر: Atherosclerosis, 315, 1-9. Elsevier Ireland Ltd

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Enterocyte, Ubiquitin-Protein Ligases, 030204 cardiovascular system & hematology, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Ezetimibe, Internal medicine, medicine, Animals, Cholesterol metabolism, TICE, Liver X receptor, Receptor, Liver X Receptors, biology, Chemistry, Cholesterol, Ubiquitination, food and beverages, Orphan Nuclear Receptors, Ubiquitin ligase, Intestines, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, LDLR, Receptors, LDL, IDOL, LDL receptor, biology.protein, lipids (amino acids, peptides, and proteins), LXR, Cardiology and Cardiovascular Medicine, Lipoprotein, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadca31bfc399e7a7a2573f7b82e1a09Test
https://pure.amc.nl/en/publications/regulation-of-intestinal-ldlr-by-the-lxridol-axisTest(6a64ee1d-17dd-474a-a545-fbf6e6d967c8).html

المؤلفون: Ambrosius P. Snijders, Atanu Chakraborty, Vesela Encheva, Alessandro Annibaldi, Mathias Rosenfeldt, Paula Moreno, Marco A. Calzado, Rocio Sancho, Jessica K. Nelson, Axel Behrens, Richard Mitter, E. Josue Ruiz, Markus E. Diefenbacher, Gianmaria Liccardi, Pascal Meier, Fabio Pucci

المصدر: The Journal of Experimental Medicine
Ruiz, E J, Diefenbacher, M E, Nelson, J K, Sancho, R, Pucci, F, Chakraborty, A, Moreno, P, Annibaldi, A, Liccardi, G, Encheva, V, Mitter, R, Rosenfeldt, M, Snijders, A P, Meier, P, Calzado, M A & Behrens, A 2019, ' LUBAC determines chemotherapy resistance in squamous cell lung cancer ', The Journal of experimental medicine, vol. 216, no. 2, pp. 450-465 . https://doi.org/10.1084/jem.20180742Test

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, medicine.medical_treatment, Immunology, Adenocarcinoma of Lung, Drug resistance, Article, Proto-Oncogene Proteins p21(ras), Mice, 03 medical and health sciences, 0302 clinical medicine, Multienzyme Complexes, medicine, Carcinoma, Animals, Humans, Immunology and Allergy, Neoplasm, ddc:610, Lung cancer, Research Articles, Cisplatin, Chemotherapy, business.industry, Ubiquitination, medicine.disease, Chemotherapy regimen, 3. Good health, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Cancer research, Adenocarcinoma, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938586481f7b5e9f80a52af1980992d2Test
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-227146Test

المؤلفون: Peter L. Hordijk, Igor Kovacevic, Saskia Scheij, Emma C. L. Cook, Noam Zelcer, Jessica K. Nelson, Anke Loregger, Huib Ovaa, Marten A. Hoeksema

المساهمون: Graduate School, Medical Biochemistry, ACS - Diabetes & metabolism, ACS - Atherosclerosis & ischemic syndromes, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Gastroenterology Endocrinology Metabolism, Landsteiner Laboratory, AII - Inflammatory diseases, Physiology, ICaR - Ischemia and repair

المصدر: Journal of biological chemistry, 291(9), 4813-4825. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 291(9), 4813-4825. American Society for Biochemistry and Molecular Biology Inc.
Nelson, J K, Cook, E C L, Loregger, A, Hoeksema, M A, Scheij, S, Kovacevic, I, Hordijk, P L, Ovaa, H & Zelcer, N 2016, ' Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake ', Journal of Biological Chemistry, vol. 291, no. 9, pp. 4813-4825 . https://doi.org/10.1074/jbc.M115.698688Test

مصطلحات موضوعية: 0301 basic medicine, Ubiquitin-Specific Proteases/antagonists & inhibitors, Transcription, Genetic, LDL/metabolism, Recombinant Proteins/chemistry, Biochemistry, Transcription, Genetic/drug effects, Mice, Ubiquitin, Genes, Reporter, Orphan Nuclear Receptors/genetics, Receptors, Transcriptional regulation, Receptors, LDL/genetics, Enzyme Inhibitors, Promoter Regions, Genetic, Ubiquitin-Protein Ligases/chemistry, Cells, Cultured, Liver X Receptors, Enzyme Inhibitors/pharmacology, Cultured, biology, Ubiquitination/drug effects, Recombinant Fusion Proteins/chemistry, Orphan Nuclear Receptors, Lipids, Recombinant Proteins, Ubiquitin ligase, Absorption, Physiological, Lipoproteins, LDL, Physiological/drug effects, lipids (amino acids, peptides, and proteins), Ubiquitin-Specific Proteases, Transcription, Absorption, Physiological/drug effects, Lysosomes/drug effects, Recombinant Fusion Proteins, Ubiquitin-Protein Ligases, Cells, Lipoproteins, Human Umbilical Vein Endothelial Cells/cytology, LDL/genetics, Absorption, Cell Line, Promoter Regions, 03 medical and health sciences, Lipoproteins, LDL/metabolism, Human Umbilical Vein Endothelial Cells, Animals, Humans, Liver X receptor, Molecular Biology, Post-transcriptional regulation, Transcription factor, Promoter Regions, Genetic/drug effects, Reporter, Genetic/drug effects, Ubiquitination, Proteolysis/drug effects, Cell Biology, 030104 developmental biology, Nuclear receptor, Receptors, LDL, Amino Acid Substitution, Genes, LDL receptor, Proteolysis, Mutation, biology.protein, Lysosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cedf0913ddcfb2603c43cc631340d66dTest
https://doi.org/10.1074/jbc.m115.698688Test

المؤلفون: Rossella Avagliano Trezza, Claire Heride, Vincenzo Sorrentino, Sylvie Urbé, Jessica K. Nelson, Ben Distel, Noam Zelcer

المساهمون: Other departments, Graduate School, AII - Amsterdam institute for Infection and Immunity, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences

المصدر: Circulation research, 118(3), 410-419. Lippincott Williams and Wilkins

مصطلحات موضوعية: 0301 basic medicine, Physiology, Ubiquitin-Protein Ligases, Regulator, Plasma protein binding, Transfection, Article, 03 medical and health sciences, Ubiquitin, RNA interference, Multienzyme Complexes, Endopeptidases, Enzyme Stability, Animals, Humans, cardiovascular diseases, Genetics, chemistry.chemical_classification, Mice, Knockout, DNA ligase, biology, HEK 293 cells, Ubiquitination, nutritional and metabolic diseases, Cholesterol, LDL, Hep G2 Cells, Cell biology, Ubiquitin ligase, 030104 developmental biology, HEK293 Cells, chemistry, Receptors, LDL, LDL receptor, Proteolysis, biology.protein, RNA Interference, lipids (amino acids, peptides, and proteins), Cardiology and Cardiovascular Medicine, Ubiquitin Thiolesterase, HeLa Cells, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cf8f8c8a4798afe202e37e36e3e53fTest
https://doi.org/10.1161/circresaha.115.307298Test