-
1
المؤلفون: Neil Moss, Lee Fader, Jeremy R Richman, Stanley Kugler, Matthew A. Cerny, Jennifer Burke, Raquel Arenas, Derek Cogan, Federico Colombo, Maolin Yu, Kosea Frederick, John Lord, Zhidong Chen, Jean-Huges Parmentier, Balestra Michael, Nicholas F. Brown, Steven M. Weldon, Xin Guo, Daniel R. Goldberg, Michael Zhang, Holly Clifford, Jennifer Schmenk, Kenneth M. Meyers, Daniel Richard Marshall, Keith R Hornberger
المصدر: Bioorganic & Medicinal Chemistry Letters. 28:979-984
مصطلحات موضوعية: 0301 basic medicine, Aldosterone synthase, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Drug Discovery, medicine, Cytochrome P-450 CYP11B2, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Aldosterone, Dose-Response Relationship, Drug, Molecular Structure, ATP synthase, biology, Organic Chemistry, Isoxazoles, Metabolism, In vitro, 030104 developmental biology, Enzyme, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Hepatocyte, biology.protein, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b0efa78c0594d187a77fbd86938a66Test
https://doi.org/10.1016/j.bmcl.2017.12.015Test -
2
المصدر: The Journal of Steroid Biochemistry and Molecular Biology. 154:197-205
مصطلحات موضوعية: Aldosterone synthase, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Biochemistry, chemistry.chemical_compound, Endocrinology, Mineralocorticoid receptor, Corticosterone, Internal medicine, Adrenal Glands, medicine, Animals, Cytochrome P-450 CYP11B2, Humans, Steroid 11-beta-hydroxylase, Molecular Biology, chemistry.chemical_classification, Aldosterone, biology, Adrenal gland, Cell Biology, Kinetics, Macaca fascicularis, medicine.anatomical_structure, Enzyme, chemistry, Zona glomerulosa, Models, Animal, biology.protein, Steroid 11-beta-Hydroxylase, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24878bf5a959ad347692ffb309c1910Test
https://doi.org/10.1016/j.jsbmb.2015.08.004Test -
3
المؤلفون: Young-Sun Yang, Cody L. Fullenwider, Jennifer Schmenk, Michael Fisher, J. Matthew Hutzler, Daniel R. Albaugh
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 40(2)
مصطلحات موضوعية: Animal Use Alternatives, Drug Evaluation, Preclinical, Pharmaceutical Science, Hepatic clearance, Pharmacology, Cryopreservation, Substrate Specificity, Zaleplon, CARBAZERAN, Cytosol, Pharmacokinetics, Enzyme Stability, medicine, Humans, Enzyme Inhibitors, Intestinal Mucosa, Aldehyde oxidase, Cells, Cultured, biology, Chemistry, Hydralazine, Enzyme assay, Aldehyde Oxidase, Kinetics, Biochemistry, Pharmaceutical Preparations, biology.protein, Hepatocytes, Oxidation-Reduction, Algorithms, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266e930d34e95b3f30b1bde03962b867Test
https://pubmed.ncbi.nlm.nih.gov/22031625Test