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1دورية أكاديمية
المؤلفون: Townsend, Elizabeth C, Murakami, Mark A, Christodoulou, Alexandra, Christie, Amanda L, Köster, Johannes, DeSouza, Tiffany A, Morgan, Elizabeth A, Kallgren, Scott P, Liu, Huiyun, Wu, Shuo-Chieh, Plana, Olivia, Montero, Joan, Stevenson, Kristen E, Rao, Prakash, Vadhi, Raga, Andreeff, Michael, Armand, Philippe, Ballen, Karen K, Barzaghi-Rinaudo, Patrizia, Cahill, Sarah, Clark, Rachael A, Cooke, Vesselina G, Davids, Matthew S, DeAngelo, Daniel J, Dorfman, David M, Eaton, Hilary, Ebert, Benjamin L, Etchin, Julia, Firestone, Brant, Fisher, David C, Freedman, Arnold S, Galinsky, Ilene A, Gao, Hui, Garcia, Jacqueline S, Garnache-Ottou, Francine, Graubert, Timothy A, Gutierrez, Alejandro, Halilovic, Ensar, Harris, Marian H, Herbert, Zachary T, Horwitz, Steven M, Inghirami, Giorgio, Intlekofer, Andrew M, Ito, Moriko, Izraeli, Shai, Jacobsen, Eric D, Jacobson, Caron A, Jeay, Sébastien, Jeremias, Irmela, Kelliher, Michelle A, Koch, Raphael, Konopleva, Marina, Kopp, Nadja, Kornblau, Steven M, Kung, Andrew L, Kupper, Thomas S, LeBoeuf, Nicole R, LaCasce, Ann S, Lees, Emma, Li, Loretta S, Look, A Thomas, Murakami, Masato, Muschen, Markus, Neuberg, Donna, Ng, Samuel Y, Odejide, Oreofe O, Orkin, Stuart H, Paquette, Rachel R, Place, Andrew E, Roderick, Justine E, Ryan, Jeremy A, Sallan, Stephen E, Shoji, Brent, Silverman, Lewis B, Soiffer, Robert J, Steensma, David P, Stegmaier, Kimberly, Stone, Richard M, Tamburini, Jerome, Thorner, Aaron R, van Hummelen, Paul, Wadleigh, Martha, Wiesmann, Marion, Weng, Andrew P, Wuerthner, Jens U, Williams, David A, Wollison, Bruce M, Lane, Andrew A, Letai, Anthony, Bertagnolli, Monica M, Ritz, Jerome, Brown, Myles, Long, Henry, Aster, Jon C, Shipp, Margaret A, Griffin, James D, Weinstock, David M
المصدر: Cancer Cell. 29(4)
مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biotechnology, Clinical Trials and Supportive Activities, Orphan Drug, Clinical Research, Hematology, Cancer, Rare Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Good Health and Well Being, Animals, Antineoplastic Agents, Biomarkers, Tumor, Cell Lineage, Female, Gene Expression Profiling, Genes, p53, Heterografts, Humans, Internet, Isoquinolines, Leukemia, Leukemia, Experimental, Lymphoma, Male, Mice, Mice, Inbred NOD, Molecular Targeted Therapy, Neoplasm Proteins, Neoplasm Transplantation, Phenotype, Piperazines, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Proteome, Proto-Oncogene Proteins c-mdm2, Random Allocation, Randomized Controlled Trials as Topic, Research Design, Tissue Banks, Transcriptome, Xenograft Model Antitumor Assays, Neurosciences, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/2s38q1mgTest
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2دورية أكاديمية
المؤلفون: Corminboeuf, Olivier, Diethelm, Stefan, Zumbrunn, Cornelia, Lyothier, Isabelle, Niggli, Nadja, Gnerre, Carmela, Jeay, Sébastien, Lehembre, François, Boss, Christoph
المصدر: ChemMedChem; Jan2024, Vol. 19 Issue 2, p1-6, 6p
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3دورية أكاديمية
المؤلفون: Bauer, Sebastian, Demetri, George D, Halilovic, Ensar, Dummer, Reinhard, Meille, Christophe, Tan, Daniel S W, Guerreiro, Nelson, Jullion, Astrid, Ferretti, Stephane, Jeay, Sébastien, van Bree, Laurence, Hourcade-Potelleret, Florence, Wuerthner, Jens U, Fabre, Claire, Cassier, Philippe A
المصدر: Bauer, Sebastian; Demetri, George D; Halilovic, Ensar; Dummer, Reinhard; Meille, Christophe; Tan, Daniel S W; Guerreiro, Nelson; Jullion, Astrid; Ferretti, Stephane; Jeay, Sébastien; van Bree, Laurence; Hourcade-Potelleret, Florence; Wuerthner, Jens U; Fabre, Claire; Cassier, Philippe A (2021). Pharmacokinetic–pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies. British Journal of Cancer, 125(5):687-698.
مصطلحات موضوعية: Dermatology Clinic, 610 Medicine & health, Cancer Research, Oncology
وصف الملف: application/pdf
العلاقة: https://www.zora.uzh.ch/id/eprint/209201/1/918_Bauer_S._et_al._Pharmacokinetic-pharmacodynamic_guided_optimisation_of_dose_and_schedule_of_CGM097,_an_HDM2_inhibitor_Br_J_Cancer_2021.pdfTest; info:pmid/34140638; urn:issn:0007-0920
الإتاحة: https://doi.org/10.5167/uzh-20920110.1038/s41416-021-01444-4Test
https://www.zora.uzh.ch/id/eprint/209201Test/
https://www.zora.uzh.ch/id/eprint/209201/1/918_Bauer_S._et_al._Pharmacokinetic-pharmacodynamic_guided_optimisation_of_dose_and_schedule_of_CGM097,_an_HDM2_inhibitor_Br_J_Cancer_2021.pdfTest -
4كتاب
المؤلفون: von Korff, Modest, Corminboeuf, Olivier, Gatfield, John, Jeay, Sébastien, Reymond, Isabelle, Sander, Thomas
المصدر: Artificial Neural Networks and Machine Learning – ICANN 2019: Workshop and Special Sessions ; Lecture Notes in Computer Science ; page 741-746 ; ISSN 0302-9743 1611-3349 ; ISBN 9783030304928 9783030304935
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5دورية أكاديمية
المؤلفون: Chapeau, Emilie A., Gembarska, Agnieszka, Durand, Eric Y., Mandon, Emeline, Estadieu, Claire, Romanet, Vincent, Wiesmann, Marion, Tiedt, Ralph, Lehar, Joseph, deWeck, Antoine, Rad, Roland, Barys, Louise, Jeay, Sebastien, Ferretti, Stephane, Kauffmann, Audrey, Sutter, Esther, Grevot, Armelle, Moulin, Pierre, Murakami, Masato, Sellers, William R., Hofmann, Francesco, Jensen, Michael Rugaard
المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2017 Mar . 114(12), 3151-3156.
الوصول الحر: https://www.jstor.org/stable/26480174Test
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6دورية أكاديمية
المؤلفون: Corminboeuf, Olivier, Diethelm, Stefan, Zumbrunn, Cornelia, Lyothier, Isabelle, Niggli, Nadja, Gnerre, Carmela, Jeay, Sébastien, Lehembre, François, Boss, Christoph
المصدر: ChemMedChem ; volume 19, issue 2 ; ISSN 1860-7179 1860-7187
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7دورية أكاديمية
المؤلفون: Reuther, Clemens, Heinzle, Vera, Nölting, Svenja, Herterich, Sabine, Hahner, Stefanie, Halilovic, Ensar, Jeay, Sébastien, Wuerthner, Jens U, Aristizabal Prada, Elke Tatjana, Spöttl, Gerald, Maurer, Julian, Auernhammer, Christoph J
المصدر: Reuther, Clemens; Heinzle, Vera; Nölting, Svenja; Herterich, Sabine; Hahner, Stefanie; Halilovic, Ensar; Jeay, Sébastien; Wuerthner, Jens U; Aristizabal Prada, Elke Tatjana; Spöttl, Gerald; Maurer, Julian; Auernhammer, Christoph J (2018). The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. Neuroendocrinology, 106(1):1-19.
مصطلحات موضوعية: Clinic for Endocrinology and Diabetology, 610 Medicine & health
وصف الملف: application/pdf
العلاقة: https://www.zora.uzh.ch/id/eprint/208189/1/document.pdfTest; info:pmid/27871087; urn:issn:0028-3835
الإتاحة: https://doi.org/10.5167/uzh-20818910.1159/000453369Test
https://www.zora.uzh.ch/id/eprint/208189Test/
https://www.zora.uzh.ch/id/eprint/208189/1/document.pdfTest -
8دورية أكاديمية
المؤلفون: Krepler, Clemens, Sproesser, Katrin, Brafford, Patricia, Beqiri, Marilda, Garman, Bradley, Xiao, Min, Shannan, Batool, Watters, Andrea, Perego, Michela, Zhang, Gao, Vultur, Adina, Yin, Xiangfan, Liu, Qin, Anastopoulos, Ioannis N, Wubbenhorst, Bradley, Wilson, Melissa A., Xu, Wei, Karakousis, Giorgos, Feldman, Michael, Xu, Xiaowei, Amaravadi, Ravi, Gangadhar, Tara C., Elder, David E., Haydu, Lauren E., Wargo, Jennifer A., Davies, Michael A., Lu, Yiling, Mills, Gordon B., Frederick, Dennie T., Barzily-Rokni, Michal, Flaherty, Keith T., Hoon, Dave S., Guarino, Michael, Bennett, Joseph J., Ryan, Randall W., Petrelli, Nicholas J., Shields, Carol L., Terai, Mizue, Sato, Takami, Aplin, Andrew E., Roesch, Alexander, Darr, David, Angus, Steve, Kumar, Rakesh, Halilovic, Ensar, Caponigro, Giordano, Jeay, Sebastien, Wuerthner, Jens, Walter, Annette, Ocker, Matthias, Boxer, Matthew B., Schuchter, Lynn, Nathanson, Katherine L, Herlyn, Meenhard
المصدر: Kimmel Cancer Center Papers, Presentations, and Grand Rounds
مصطلحات موضوعية: BRAF inhibitor resistance, ERK inhibitor, MDM2 inhibitor, PI3K beta inhibitor, immune checkpoint blockade, in vivo models, melanoma, melanoma brain metastasis, patient-derived xenografts, targeted therapy, Dermatology, Medicine and Health Sciences, Oncology
وصف الملف: application/pdf
العلاقة: https://jdc.jefferson.edu/kimmelgrandrounds/58Test; https://jdc.jefferson.edu/context/kimmelgrandrounds/article/1058/viewcontent/1_s2.0_S2211124717314535_main.pdfTest
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9دورية أكاديمية
المؤلفون: Wang, Hui Qin, Halilovic, Ensar, Li, Xiaoyan, Liang, Jinsheng, Cao, Yichen, Rakiec, Daniel P, Ruddy, David A, Jeay, Sebastien, Wuerthner, Jens U, Timple, Noelito, Kasibhatla, Shailaja, Li, Nanxin, Williams, Juliet A, Sellers, William R, Huang, Alan, Li, Fang
المساهمون: Novartis
المصدر: eLife ; volume 6 ; ISSN 2050-084X
الإتاحة: https://doi.org/10.7554/elife.17137Test
https://cdn.elifesciences.org/articles/17137/elife-17137-v2.pdfTest
https://cdn.elifesciences.org/articles/17137/elife-17137-v2.xmlTest
https://elifesciences.org/articles/17137Test -
10دورية أكاديمية
المؤلفون: Huang, Ying, Zhang, Jeff, Sendzik, Martin, Gao, Zhenting, Sun, Yongfeng, Wang, Long, Zhang, Lijun, Blanz, Joachim, Dubost, Valerie, Chen, Zijun, Fang, Douglas, Gu, Justin, Kiffe, Michael, Li, Ling, Luo, Fangjun, Luo, Xiao, Mistry, Prakash, Pearson, David, Piaia, Alessandro, Qi, Wei, Scheufler, Clemens, Terranova, Remi, Weiss, Andreas, Yu, Zhengtian, Zeng, Jue, Zhang, Hailong, Zhang, Jiangwei, Zhang, Qiong, Zhao, Kehao, Zhao, Mengxi, Atadja, Peter, Dillon, Michael, Jeay, Sebastien Jeay, Li, En, Moggs, Jonathan, Pissot Soldermann, Carole, Oyang, Counde, Lingel, Andreas
العلاقة: Huang, Ying, Zhang, Jeff, Sendzik, Martin, Gao, Zhenting, Sun, Yongfeng, Wang, Long, Zhang, Lijun, Blanz, Joachim, Dubost, Valerie, Chen, Zijun, Fang, Douglas, Gu, Justin, Kiffe, Michael, Li, Ling, Luo, Fangjun, Luo, Xiao, Mistry, Prakash, Pearson, David, Piaia, Alessandro, Qi, Wei, Scheufler, Clemens, Terranova, Remi, Weiss, Andreas, Yu, Zhengtian, Zeng, Jue, Zhang, Hailong, Zhang, Jiangwei, Zhang, Qiong, Zhao, Kehao, Zhao, Mengxi, Atadja, Peter, Dillon, Michael, Jeay, Sebastien Jeay, Li, En, Moggs, Jonathan, Pissot Soldermann, Carole, Oyang, Counde and Lingel, Andreas (2022) Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. Journal of Medicinal Chemistry, 65 (7). pp. 5317-5333. ISSN 0022-26231520-4804