نتائج البحث - "Jean-Pierre Bourgeois"

المساهمون: Génétique humaine et fonctions cognitives - Human Genetics and Cognitive Functions (GHFC (UMR_3571 / U-Pasteur_1)), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris]-Université de Paris (UP), Neurobiologie intégrative des Systèmes cholinergiques / Integrative Neurobiology of Cholinergic Systems (NISC), Sorbonne Université (SU)-Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Collège doctoral [Sorbonne universités], Sorbonne Université (SU), The authors are thankful to the Clinical Investigation Center of Robert Debré hospital for assistance with patient recruitment and to Dr. Alexandra Benchoua who performed the initial iPSC reprogramming. The French Ministry of Education and the LabEx BioPsy provided the funding for AV’s PhD. Other funding for this study were provided by grants from the French National Research Agency ANR (ANR-13-SAMA-0006, SynDivAutism), the Bettencourt-Schueller Foundation, the Cognacq Jay Foundation, the Fondamental Foundation and the Fondation pour la Recherche Médicale 'FRM Equipe 2019'. We gratefully acknowledge the UtechS Photonic Bioimaging (Imagopole), C2RT, Institut Pasteur, supported by the French National Research Agency (France BioImaging, ANR-10-INSB-04, Investments for the future). We also gratefully acknowledge the help of Image Analysis Hub of the Institut Pasteur for this work. NINDS Repository sample numbers corresponding to the sample used in this study is GM04603 ('4603')., ANR-13-SAMA-0006,SynDivAutism,Diversité Synaptique dans l'autisme(2013), ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut Pasteur [Paris] (IP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Collège Doctoral

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.13315. ⟨10.1038/s41598-020-70056-4⟩
Scientific Reports, 2020, 10 (1), pp.13315. ⟨10.1038/s41598-020-70056-4⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: 0301 basic medicine, Autism Spectrum Disorder, [SDV]Life Sciences [q-bio], [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Induced Pluripotent Stem Cells, lcsh:Medicine, Nerve Tissue Proteins, Diseases, Mice, SCID, Stem cells, Biology, medicine.disease_cause, Article, Cell Line, 03 medical and health sciences, Mice, 0302 clinical medicine, Neural Stem Cells, Postsynaptic potential, In vivo, Mice, Inbred NOD, medicine, Genetics, Animals, Humans, lcsh:Science, Mutation, Transplantation Chimera, Multidisciplinary, Pyramidal Cells, lcsh:R, Human brain, Phenotype, Cortex (botany), Cell biology, Transplantation, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Cell culture, Heterografts, lcsh:Q, 030217 neurology & neurosurgery, Stem Cell Transplantation, Neuroscience