المؤلفون: Gandini, Annachiara, Gonçalves, Ana Elisa, Strocchi, Silvia, Albertini, Claudia, Janočková, Jana, Tramarin, Anna, Grifoni, Daniela, Poeta, Eleonora, Soukup, Ondrej, Muñoz-Torrero, Diego, Monti, Barbara, Sabaté, Raimon, Bartolini, Manuela, Legname, Giuseppe, Bolognesi, Maria Laura

المساهمون: Gandini, Annachiara, Gonçalves, Ana Elisa, Strocchi, Silvia, Albertini, Claudia, Janočková, Jana, Tramarin, Anna, Grifoni, Daniela, Poeta, Eleonora, Soukup, Ondrej, Muñoz-Torrero, Diego, Monti, Barbara, Sabaté, Raimon, Bartolini, Manuela, Legname, Giuseppe, Bolognesi, Maria Laura

مصطلحات موضوعية: aggregation inhibitor, bivalent ligand, multitarget-directed ligand, protein aggregate, tau protein, β-amyloid

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36445009; info:eu-repo/semantics/altIdentifier/wos/WOS:000894025200001; volume:13; issue:23; firstpage:3314; lastpage:3329; numberofpages:16; journal:ACS CHEMICAL NEUROSCIENCE; https://hdl.handle.net/11585/917259Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85143440253

الإتاحة: https://doi.org/10.1021/acschemneuro.2c00357Test
https://hdl.handle.net/11585/917259Test

المؤلفون: Chrienova, Z., Nepovimova, E., Andrys, R., Dolezal, R., Janockova, Jana, Muckova, Lubica, Fabova, L., Soukup, Ondrej, Oleksak, Patrik, Valisa, M., Korabecny, J., Marco-Contelles, José, Kuca, K.

المساهمون: Ministry of Education, Youth and Sports (Czech Republic), Czech Science Foundation, Agencia Estatal de Investigación (España), Universidad Camilo José Cela

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI//PDI-2019-105813RB-C21; Publisher's version; http://dx.doi.org/10.1080/14756366.2022.2122054Test; Sí; Journal of Enzyme Inhibition and Medicinal Chemistry 37: 2605- 2620 (2022); http://hdl.handle.net/10261/288371Test; http://dx.doi.org/10.13039/501100008742Test; http://dx.doi.org/10.13039/501100011033Test

الإتاحة: https://doi.org/10.1080/14756366.2022.2122054Test
https://doi.org/10.13039/501100008742Test
https://doi.org/10.13039/501100011033Test
http://hdl.handle.net/10261/288371Test

المؤلفون: Dgachi, Youssef, Bautista-Aguilera, Oscar M., Benchekroun, Mohamed, Martin, Hélène, Bonet, Alexandre, Knez, Damijan, Godyń, Justyna, Malawska, Barbara, Gobec, Stanislav, Chioua, Mourad, Janockova, Jana, Soukup, Ondrej, Chabchoub, Fakher, Marco-Contelles, José, Ismaili, Lhassane

المصدر: Molecules, vol. 21, no. 5, art 634, 2016. ; ISSN: 1420-3049

مصطلحات موضوعية: Alzheimer's disease, quinazolinones, multicomponent reactions, multitarget-directed ligands, antioxidants, cholinesterase inhibitors, hepatotoxicity, Alzheimerjeva bolezen, info:eu-repo/classification/udc/615.2:616.894

وصف الملف: application/pdf; text/url

العلاقة: info:eu-repo/grantAgreement/Drugi/Government of Spain/SAF2016-65586-R; info:eu-repo/grantAgreement/Drugi/MH CZ- DRO/UHHK%2000179906; https://repozitorij.uni-lj.si/IzpisGradiva.php?id=130298Test; https://repozitorij.uni-lj.si/Dokument.php?id=147372&dnTest=; https://repozitorij.uni-lj.si/Dokument.php?id=147371&dnTest=; https://plus.si.cobiss.net/opac7/bib/4083825?lang=slTest

الإتاحة: https://doi.org/10.3390/molecules21050634Test
https://repozitorij.uni-lj.si/IzpisGradiva.php?id=130298Test
https://repozitorij.uni-lj.si/Dokument.php?id=147372&dnTest=
https://repozitorij.uni-lj.si/Dokument.php?id=147371&dnTest=
https://plus.si.cobiss.net/opac7/bib/4083825?lang=slTest

المؤلفون: Janockova, Jana, Slovinska, Lucia, Harvanova, Denisa, Spakova, Timea, Rosocha, Jan

المساهمون: OPENMED

المصدر: Journal of Biomedical Science ; volume 28, issue 1 ; ISSN 1423-0127

مصطلحات موضوعية: Pharmacology (medical), Biochemistry (medical), Cell Biology, Clinical Biochemistry, Molecular Biology, General Medicine, Endocrinology, Diabetes and Metabolism

الإتاحة: https://doi.org/10.1186/s12929-021-00736-4Test

المؤلفون: Dgachi, Youssef, Martin, Helene, Martin, Hélène, Malek, R, Jun, D., Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Iriepa, Isabel, Moraleda, Ignacio, Maalej, Enma, Carreiras, M. Carmo, Refouvelet, B., Chabchoub, Fakher, Marco-Contelles, José, Ismaili, Lhassane

المساهمون: Ministerio de Economía, Industria y Competitividad (España), European Commission

مصطلحات موضوعية: Alzheimer disease, Kojic acid, Multitarget small molecules, Tacrine

العلاقة: Publisher's version; http://dx.doi.org/10.1080/14756366.2018.1538136Test; Sí; e-issn: 1475-6374; Journal of Enzyme Inhibition and Medicinal Chemistry 34: 163-170 (2019); http://hdl.handle.net/10261/175021Test; http://dx.doi.org/10.13039/501100000780Test; http://dx.doi.org/10.13039/501100010198Test

الإتاحة: https://doi.org/10.1080/14756366.2018.1538136Test
https://doi.org/10.13039/501100000780Test
https://doi.org/10.13039/501100010198Test
http://hdl.handle.net/10261/175021Test

المؤلفون: Janockova, Jana, Korabecny, Jan, Plsikova, Jana, Babkova, Katerina, Konkolova, Eva, Kucerova, Dana, Vargova, Jana, Koval, Jan, Jendzelovsky, Rastislav, Fedorocko, Peter, Kasparkova, Jana, Brabec, Viktor, Rosocha, Jan, Soukup, Ondrej, Hamulakova, Slavka, Kuca, Kamil, Kozurkova, Maria

المساهمون: the University of Defense, MH CZ-DRO, UHHK, VEGA, VVGS, Operational Program Research and Innovations

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry ; volume 34, issue 1, page 877-897 ; ISSN 1475-6366 1475-6374

الإتاحة: https://doi.org/10.1080/14756366.2019.1593159Test

المؤلفون: Mezeiova, Eva, Spilovska, Katarina, Nepovimova, Eugenie, Gorecki, Lukas, Soukup, Ondrej, Dolezal, Rafael, Malinak, David, Janockova, Jana, Jun, Daniel, Kuca, Kamil, Korabecny, Jan

المساهمون: Ministry of Health of the Czech Republic, National Institute of Mental Health

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry ; volume 33, issue 1, page 583-606 ; ISSN 1475-6366 1475-6374

الإتاحة: https://doi.org/10.1080/14756366.2018.1443326Test

المؤلفون: Dgachi, Youssef, Martin, Hélène, Malek, Rim, Jun, Daniel, Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Iriepa, Isabel, Moraleda, Ignacio, Maalej, Emna, Carreiras, M. Carmo, Refouvelet, Bernard, Chabchoub, Fakher, Marco-Contelles, José, Ismaili, Lhassane

المساهمون: Regional Council of Franche-Comte, Faculty of Military Health Sciences, University of Defense, MH CZ – DRO, MINECO (Spain), EU

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry ; volume 34, issue 1, page 163-170 ; ISSN 1475-6366 1475-6374

الإتاحة: https://doi.org/10.1080/14756366.2018.1538136Test

المؤلفون: Bautista-Aguilera, Óscar M., Hagenow, Stefanie, Palomino-Antolin, Alejandra, Farré-Alins, Víctor, Ismaili, Lhassane, Joffrin, Pierre-Louis, Jimeno, María L., Soukup, Ondřej, Janočková, Jana, Kalinowsky, Lena, Proschak, Ewgenij, Iriepa, Isabel, Moraleda, Ignacio, Schwed, Johannes S., Romero Martínez, Alejandro, López-Muñoz, Francisco, Chioua, Mourad, Egea, Javier, Ramsay, Rona R., Marco-Contelles, José, Stark, Holger

المصدر: Bautista-Aguilera , Ó M , Hagenow , S , Palomino-Antolin , A , Farré-Alins , V , Ismaili , L , Joffrin , P-L , Jimeno , M L , Soukup , O , Janočková , J , Kalinowsky , L , Proschak , E , Iriepa , I , Moraleda , I , Schwed , J S , Romero Martínez , A , López-Muñoz , F , Chioua , M , Egea , J , Ramsay , R R , Marco-Contelles , J & Stark , H 2017 , ' Multitarget-directed ligands combining cholinesterase and monoamine oxidase inhibition ....

مصطلحات موضوعية: Antioxidants, Drug design, Inhibitors, Multitarget drugs, Neurological agents

وصف الملف: application/pdf

العلاقة: https://research-portal.st-andrews.ac.uk/en/researchoutput/multitargetdirected-ligands-combining-cholinesterase-and-monoamine-oxidase-inhibition-with-histamine-h3r-antagonism-for-neurodegenerative-diseasesTest(f4f5504d-7acc-4249-981b-044cc4a90c7d).html

الإتاحة: https://doi.org/10.1002/anie.201706072Test
https://research-portal.st-andrews.ac.uk/en/researchoutput/multitargetdirected-ligands-combining-cholinesterase-and-monoamine-oxidase-inhibition-with-histamine-h3r-antagonism-for-neurodegenerative-diseasesTest(f4f5504d-7acc-4249-981b-044cc4a90c7d).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/15938/1/Ramsay_2017_AngewChemie_Multi_target_AAM.pdfTest

المؤلفون: Hroch, Lukas, Guest, Patrick, Benek, Ondrej, Soukup, Ondrej, Janockova, Jana, Dolezal, Rafael, Kuca, Kamil, Aitken, Laura, Smith, Terry K., Gunn-Moore, Frank, Zala, Dominykas, Ramsay, Rona R., Musilek, Kamil

المصدر: Hroch , L , Guest , P , Benek , O , Soukup , O , Janockova , J , Dolezal , R , Kuca , K , Aitken , L , Smith , T K , Gunn-Moore , F , Zala , D , Ramsay , R R & Musilek , K 2017 , ' Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment ' , Bioorganic & Medicinal Chemistry , vol. 25 , no. 3 , pp. 1143-1152 . https://doi.org/10.1016/j.bmc.2016.12.029Test

مصطلحات موضوعية: Alzheimer's disease (AD), Monoamine oxidase (MAO), Amyloid-beta peptide (Aβ), Mitochondrial amyloid-binding alcohol dehydrogenase (ABAD), 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10), Horseradish peroxidase (HRP)

وصف الملف: application/pdf

العلاقة: https://research-portal.st-andrews.ac.uk/en/researchoutput/synthesis-and-evaluation-of-frentizolebased-indolyl-thiourea-analogues-as-maoabad-inhibitors-for-alzheimers-disease-treatmentTest(5e51b928-c712-4e9e-b7e8-8d62bd7d0834).html

الإتاحة: https://doi.org/10.1016/j.bmc.2016.12.029Test
https://research-portal.st-andrews.ac.uk/en/researchoutput/synthesis-and-evaluation-of-frentizolebased-indolyl-thiourea-analogues-as-maoabad-inhibitors-for-alzheimers-disease-treatmentTest(5e51b928-c712-4e9e-b7e8-8d62bd7d0834).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/12391/1/Ramsay_2016_BMC_frentizole_based_AAM.pdfTest