المؤلفون: Kallanthottathil G. Rajeev, Nicole M. Gaudelli, Yusuf S. Nasrullah, Soumyashree A. Gangopadhyay, Andrew M. Bellinger, Sara P. Garcia, James Madsen, Jamie E. DeNizio, Athul Sanjeev, Lisa N. Kasiewicz, Giuseppe Ciaramella, Aaron Beach, Ellen Rohde, Anne Marie Mazzola, Thomas V. Colace, Kui Wang, Sowmya Iyer, Caroline W. Reiss, Padma Malyala, Steven H. Y. Fan, Victoria Clendaniel, Christopher J. Cheng, Jennifer Lavoie, Taiji Mizoguchi, Yuri Matsumoto, Madeleine Shay, Kiran Musunuru, Leslie E. Stolz, Maurine C. Braun, Chaitali Dutta, Ying K. Tam, Joseph Nneji, Ryan Garrity, Alexandra C. Chadwick, Souvik Biswas, Michael Amaonye, John D. Ganey, Mary R. Stahley, Huilan Ren, Huei-Mei Chen, Kathleen Berth, Sekar Kathiresan

المصدر: Nature. 593:429-434

مصطلحات موضوعية: Male, 0301 basic medicine, Time Factors, Genetic enhancement, 030204 cardiovascular system & hematology, Pharmacology, Biology, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Genome editing, Loss of Function Mutation, In vivo, Animals, Humans, CRISPR, Gene, Cells, Cultured, Gene Editing, Gene knockdown, Multidisciplinary, Cholesterol, Adenine, PCSK9, Cholesterol, LDL, Mice, Inbred C57BL, Macaca fascicularis, 030104 developmental biology, Liver, chemistry, Models, Animal, Hepatocytes, Mutagenesis, Site-Directed, Female, CRISPR-Cas Systems, Proprotein Convertase 9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202cb5c958a9c7ceda5f4b4bf29aa718Test
https://doi.org/10.1038/s41586-021-03534-yTest

المؤلفون: Jamie E. DeNizio, Yan Wang, Simon F. Lacey, Vijay Bhoj, Tyler J. Reich, In-Young Jung, Regina M. Young, David L. Porter, John Scholler, Minnal Gupta, Julie K. Jadlowsky, Carl H. June, Todd Yoder, Christopher J. Ott, Megan M. Davis, Kathleen M. Haines, Irina Kulikovskaya, Golnaz Vahedi, Katherine T. Marcucci, Weimin Kong, Jun Xu, J. Joseph Melenhorst, John K. Everett, Joseph A. Fraietta, Marcela V. Maus, Erik F. Williams, Bruce L. Levine, Wenliang Wang, James E. Bradner, Rahul M. Kohli, Alexander Dimitri, Frederic D. Bushman, Maria Fasolino

المصدر: J Clin Invest

مصطلحات موضوعية: T-Lymphocytes, T cell, Chronic lymphocytic leukemia, Antigens, CD19, Cell, chemical and pharmacologic phenomena, Immunotherapy, Adoptive, Oxidative Phosphorylation, Epigenesis, Genetic, Immune Tolerance, medicine, Humans, Gene silencing, Receptor, B cell, Receptors, Chimeric Antigen, Chemistry, Proteins, hemic and immune systems, Azepines, General Medicine, Triazoles, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Chimeric antigen receptor, Bromodomain, medicine.anatomical_structure, Cancer research, Glycolysis, Immunologic Memory, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1912b4b10fb9af76123380d068f10aabTest
https://doi.org/10.1172/jci145459Test

المؤلفون: Emily B. Fabyanic, Rahul M. Kohli, Monica Yun Liu, Young Hwang, Hao Wu, Christopher S. Nabel, Jamie E. DeNizio, Emily K Schutsky, Frederic D. Bushman, Peng Hu

المصدر: Nature biotechnology

مصطلحات موضوعية: 0301 basic medicine, 5-Hydroxymethylcytosine, Biomedical Engineering, Deamination, Bioengineering, DNA, Epigenome, Computational biology, Applied Microbiology and Biotechnology, Article, Bisulfite, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, 5-Methylcytosine, Molecular Medicine, Epigenetics, Enhancer, 030217 neurology & neurosurgery, Cytosine, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59614dfda3642999118ab50134961d7Test
https://doi.org/10.1038/nbt.4204Test

المؤلفون: Jamie E. DeNizio, Emily K Schutsky, Kiara N. Berríos, Rahul M. Kohli, Monica Yun Liu

المصدر: Current Opinion in Chemical Biology. 45:10-17

مصطلحات موضوعية: 0301 basic medicine, Methyltransferase, Computational biology, Biology, 010402 general chemistry, 01 natural sciences, Biochemistry, Genome, Article, Epigenesis, Genetic, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Dna genetics, Animals, Humans, DNA Modification Methylases, Epigenesis, Gene Editing, Adenine, DNA, Epigenome, DNA Methylation, 0104 chemical sciences, Structure and function, 030104 developmental biology, chemistry, DNA methylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb918416f7a99e21c4d6769b2c7882f6Test
https://doi.org/10.1016/j.cbpa.2018.01.016Test

المؤلفون: Kelly R Karch, Jamie E DeNizio, Ben E Black, Benjamin Aaron Garcia

المصدر: Frontiers in Genetics, Vol 4 (2013)

مصطلحات موضوعية: Chromatin, Histone Code, Mass Spectrometry, Proteomics, histone, post-translational modification, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00264/fullTest; https://doaj.org/toc/1664-8021Test

الوصول الحر: https://doaj.org/article/0c248f412f414f52a745ad2e66ec6d35Test

المؤلفون: Edward Chuang, Ryan R. Cupo, Meredith E. Jackrel, Amber Tariq, Korrie L. Mack, Kim A. Caldwell, Laura M. Castellano, Jamie E. DeNizio, Hanna Kim, James Shorter, JiaBei Lin, Xiaohui Yan, Guy A. Caldwell

مصطلحات موضوعية: Alpha-synuclein, chemistry.chemical_compound, chemistry, Neurodegeneration, Dopaminergic, Toxicity, mental disorders, medicine, Substrate specificity, medicine.disease, Cell biology, nervous system diseases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2841ba1d281e017ba4cd2fea677a6bfTest

المؤلفون: David A. Hewitt, Jamie E. DeNizio

المصدر: Sports Medicine-Open

مصطلحات موضوعية: Infection risk, Antibiotic resistance, Secondary infection, Environmentally acquired infections, Physical Therapy, Sports Therapy and Rehabilitation, Disease, Leading Article, 03 medical and health sciences, 0302 clinical medicine, Environmental health, Orthopedics and Sports Medicine, 030212 general & internal medicine, Risk of infection, Mountain- biking, Outbreak, 030229 sport sciences, Outdoor sports, 6. Clean water, 3. Good health, Obstacle-course races, Geography, 13. Climate action, Infectious disease (medical specialty), Developed country, Triathlons

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb5d2908f1648c62ddd6a9e3ead9110Test
http://europepmc.org/articles/PMC6694362Test

المؤلفون: Uday Ghanty, Jamie E. DeNizio, Alexander C. Drohat, Rahul M. Kohli, Blaine J. Dow, Juan C. Serrano

المصدر: J Mol Biol

مصطلحات موضوعية: DNA Repair, Article, Dioxygenases, Epigenesis, Genetic, Cytosine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, Proto-Oncogene Proteins, Humans, Molecular Biology, 030304 developmental biology, 5-Hydroxymethylcytosine, 0303 health sciences, Base excision repair, Molecular biology, Thymine DNA Glycosylase, Thymine, DNA Demethylation, DNA-Binding Proteins, 5-Methylcytosine, DNA demethylation, CpG site, chemistry, CpG Islands, Thymine-DNA glycosylase, Oxidation-Reduction, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9183bd22593d943fe497e34c59ea48f0Test
https://doi.org/10.1016/j.jmb.2021.166877Test

المؤلفون: Tong Wang, Roberto Bonasio, Emily J. Shields, Marisa S. Bartolomei, Blake A. Caldwell, Christopher Krapp, Yemin Lan, Rahul M. Kohli, Christopher J. Lengner, N. Adrian Leu, Nana Yaa A. Amoh, Monica Yun Liu, Rexxi D. Prasasya, Jamie E. DeNizio

المصدر: Mol Cell

مصطلحات موضوعية: Somatic cell, Biology, Article, Dioxygenases, Epigenesis, Genetic, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Proto-Oncogene Proteins, Animals, Humans, Epigenetics, Enhancer, Molecular Biology, 030304 developmental biology, Demethylation, Mice, Knockout, 5-Hydroxymethylcytosine, 0303 health sciences, Cell Biology, Fibroblasts, Cellular Reprogramming, Embryo, Mammalian, Cell biology, Chromatin, DNA-Binding Proteins, Enhancer Elements, Genetic, HEK293 Cells, DNA demethylation, chemistry, Mutation, 5-Methylcytosine, NIH 3T3 Cells, Reprogramming, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ec186fd3588476ec70d7baa4611885Test
https://doi.org/10.1016/j.molcel.2020.11.045Test

المؤلفون: Jamie E. DeNizio, Martin Carroll, Christopher S. Nabel, Rahul M. Kohli

المصدر: Biochemistry. 56:2166-2169

مصطلحات موضوعية: 0301 basic medicine, Antimetabolites, Antineoplastic, Methyltransferase, Cytarabine, Myeloid leukemia, Methylation, Biology, medicine.disease, Biochemistry, Molecular biology, Article, Epigenesis, Genetic, carbohydrates (lipids), Leukemia, Myeloid, Acute, 03 medical and health sciences, Leukemia, 030104 developmental biology, DNA demethylation, hemic and lymphatic diseases, DNA methylation, DNMT1, medicine, Humans, Epigenetics, DNA Modification Methylases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b08bd13ee3f3e1e357b4a47bd8a692aTest
https://doi.org/10.1021/acs.biochem.7b00208Test