المؤلفون: Emma Rose McGlone, David C.D. Hope, Iona Davies, Marian Dore, Rob Goldin, Ben Jones, Zhigang Liu, Jia V. Li, Panagiotis A. Vorkas, Bernard Khoo, David Carling, James Minnion, Stephen R. Bloom, Tricia M-M. Tan

المصدر: Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116888- (2024)

مصطلحات موضوعية: Metabolic dysfunction-associated steatotic liver disease (MASLD), non-alcoholic Fatty Liver Disease (NAFLD), weight loss, type 2 diabetes mellitus, glucagon, glucagon-like peptide-1, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0753332224007728Test; https://doaj.org/toc/0753-3322Test

الوصول الحر: https://doaj.org/article/7c277ce7faa84cd98085788d7067ad56Test

المؤلفون: Phil Pickford, Maria Lucey, Roxana-Maria Rujan, Emma Rose McGlone, Stavroula Bitsi, Fiona B. Ashford, Ivan R. Corrêa, David J. Hodson, Alejandra Tomas, Giuseppe Deganutti, Christopher A. Reynolds, Bryn M. Owen, Tricia M. Tan, James Minnion, Ben Jones, Stephen R. Bloom

المصدر: Molecular Metabolism, Vol 51, Iss , Pp 101242- (2021)

مصطلحات موضوعية: GLP-1, Glucagon, Oxyntomodulin, Biased agonism, Partial agonism, β-arrestin, Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2212877821000879Test; https://doaj.org/toc/2212-8778Test

الوصول الحر: https://doaj.org/article/81eb48b9c1554fad855b7b0e36385ffcTest

المؤلفون: Maria Lucey, Philip Pickford, Stavroula Bitsi, James Minnion, Jan Ungewiss, Katja Schoeneberg, Guy A. Rutter, Stephen R. Bloom, Alejandra Tomas, Ben Jones

المصدر: Molecular Metabolism, Vol 37, Iss , Pp 100991- (2020)

مصطلحات موضوعية: Type 2 diabetes, Biased signalling, Glucagon-like peptide-1 receptor, Exendin-4, Trafficking, Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S221287782030065XTest; https://doaj.org/toc/2212-8778Test

الوصول الحر: https://doaj.org/article/6622263a11a0409ea4a255d09f36f3b7Test

المؤلفون: Ioannis Christakis, Rebecca Scott, James Minnion, Joyceline Cuenco, Tricia Tan, Fausto Palazzo, Stephen Bloom

المصدر: Journal of Investigative Surgery, Vol 30, Iss 3, Pp 162-169 (2017)

مصطلحات موضوعية: half-life, pharmacokinetics, metabolic clearance rate, jugular vein, femoral vein, drug, Surgery, RD1-811

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/0894-1939Test; https://doaj.org/toc/1521-0553Test

الوصول الحر: https://doaj.org/article/3aaf7f1a420b4a20835907f7527532c9Test

المؤلفون: Anna M. Kowalka, Kleopatra Alexiadou, Joyceline Cuenco, Rosemary E. Clarke, Stephane Camuzeaux, James Minnion, Emma L. Williams, Paul Bech, Sanjay Purkayastha, Ahmed R. Ahmed, Zoltan Takats, Bernard Khoo, Harry J. Whitwell, Maria G. Romero, Stephen R. Bloom, Matthew R. Lewis, Tricia M.‐M. Tan

المصدر: Clinical Endocrinology. 98:763-765

مصطلحات موضوعية: Endocrinology, Endocrinology, Diabetes and Metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ff41debe688dc30889dd62a97725f451Test
https://doi.org/10.1111/cen.14894Test

المؤلفون: Anna M. Kowalka, Kleopatra Alexiadou, Joyceline Cuenco, Rosemary E. Clarke, James Minnion, Emma L. Williams, Paul Bech, Sanjay Purkayastha, Ahmed R. Ahmed, Zoltan Takats, Harry J. Whitwell, Maria Gomez Romero, Stephen R. Bloom, Stephane Camuzeaux, Matthew R. Lewis, Bernard Khoo, Tricia M.‐M. Tan

المصدر: Clinical Endocrinology.

مصطلحات موضوعية: Endocrinology, Endocrinology, Diabetes and Metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5db84d388c9370b00fc664c1c6097987Test
https://doi.org/10.1111/cen.14846Test

المؤلفون: Charlotte E Hinds, Tricia Tan, Philip Pickford, Bryn M. Owen, David Hope, James Minnion, Stephen R. Bloom, Ben Jones

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)

مصطلحات موضوعية: Male, medicine.medical_specialty, Science, Context (language use), Body weight, Glucagon, Article, Weight loss, In vivo, Internal medicine, Weight Loss, Receptors, Glucagon, medicine, Animals, Humans, Rats, Wistar, Mice, Knockout, Pharmacology, Multidisciplinary, Dose-Response Relationship, Drug, Chemistry, medicine.disease, Mice, Inbred C57BL, HEK293 Cells, Endocrinology, Signalling, Biological Variation, Population, Liver, Hepatocytes, Medicine, Female, Anti-Obesity Agents, Metabolic syndrome, medicine.symptom, Fat metabolism, Glucagon receptor, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a0670b5baee4967ee3caf87372535eTest
https://doi.org/10.1038/s41598-021-01912-0Test

المؤلفون: James Minnion, Christophe Montaurier, François-Pierre Martin, Jacques Epelbaum, Joyceline Cuenco, Jörg Hager, Dominique Grouselle, Sylvie Mure, Yves Boirie, Jérôme Carayol, Sofia Moco, Bogdan Galusca, Bruno Estour, Yiin Ling, Thierry Thomas, Nele Gheldof, Natacha Germain, Simona Bartova

المساهمون: CHU Saint-Etienne, University Hospital and University Jean Monnet, Metabolic Health, Nestlé Research, EPFL Innovation Park, Lausanne, INSERM UMR894-Centre de Psychiatrie et Neurosciences (CPN), Universite´ Paris Descartes, Sorbonne Paris Cite, Unité de Nutrition Humaine (UNH), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Imperial College London, Nestle Research, Switzerland, ROSSI, Sabine, Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] (CHU ST-E)

المصدر: Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Wiley Open Access/Springer Verlag, 2020, 11 (5), pp.1187-1199. ⟨10.1002/jcsm.12572⟩
Journal of Cachexia, Sarcopenia and Muscle, 2020, 11 (5), pp.1187-1199. ⟨10.1002/jcsm.12572⟩
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1187-1199 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Nitrogen balance, lcsh:Diseases of the musculoskeletal system, Adolescent, Anabolism, Constitutional Thinness, Urine, Weight Gain, Bodyweight gain, lcsh:QM1-695, Excretion, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Thinness, Physiology (medical), Internal medicine, medicine, Humans, Orthopedics and Sports Medicine, Overfeeding, 2. Zero hunger, business.industry, Original Articles, lcsh:Human anatomy, Energy gap, 3. Good health, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, 030104 developmental biology, Endocrinology, Social Conditions, 030220 oncology & carcinogenesis, Body Composition, Anorectic, Lean body mass, Original Article, Female, lcsh:RC925-935, Underweight, medicine.symptom, Energy Metabolism, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Weight gain

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cb2fe4d0e3f16e79d98a3a3fa9ae83Test
https://doi.org/10.1002/jcsm.12572Test

المؤلفون: Tricia Tan, Johannes D. Veldhuis, Yoshibye Crustna, Maria Phylactou, Jessica Starikova, James Minnion, Sophie Jones, Lisa Yang, Alexander N Comninos, Pratibha Machenahalli, Risheka Ratnasabapathy, Ewa Pacuszka, Manish Modi, Chioma Izzi-Engbeaya, Pei Chia Eng, Paul Bech, Deborah Papadopoulou, George Tharakan, Waljit S. Dhillo, Derek Chan, Edouard Mills, Ali Abbara

المساهمون: Imperial College Healthcare NHS Trust- BRC Funding, National Institute for Health Research, Imperial College Healthcare NHS Trust - CLRN Funding

المصدر: The Journal of Clinical Endocrinology and Metabolism

مصطلحات موضوعية: Adult, Male, endocrine system, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Clinical Biochemistry, Context (language use), Biochemistry, Glucagon, reproduction, Endocrinology & Metabolism, Follicle-stimulating hormone, Endocrinology, Gastrointestinal Agents, Internal medicine, medicine, Humans, Single-Blind Method, follicle-stimulating hormone, Testosterone, Clinical Research Article, Cross-Over Studies, business.industry, Insulin, Biochemistry (medical), 1103 Clinical Sciences, Prognosis, glucagon, testosterone, luteinizing hormone, 1114 Paediatrics and Reproductive Medicine, Follicle Stimulating Hormone, Luteinizing hormone, business, Glucagon receptor, Biomarkers, AcademicSubjects/MED00250, hormones, hormone substitutes, and hormone antagonists, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9985f8e0a3b04ae30e1cd58fe5495429Test
https://doi.org/10.1210/clinem/dgaa164Test

المؤلفون: Johannes Broichhagen, James Minnion, Stephen J. Briddon, Joelle Goulding, Yuval Elani, Alejandra Tomas, David J. Hodson, Maria Lucey, Atsuro Oishi, Tanyel Ashik, Ben Jones, Stephen R. Bloom, Ralf Jockers, Amaara Marzook, Yifan Wang

المساهمون: Imperial College London, University of Birmingham [Birmingham], Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Kyorin University School of Medicine [Tokyo, Japan], Kyorin University [Tokyo, Japan], Leibniz Forschungsinstitut für Molekulare Pharmakolgie = Leibniz Institute for Molecular Pharmacology [Berlin, Allemagne] (FMP), Leibniz Association, Department of Chemical Engineering [London], ANR-15-CE14-0025,GlioShuttles4Metabolism,Les tanycytes transportent la leptine dans le cerveau: identification des mécanismes et rôle dans la physiopathologie de l'obésité et du diabète(2015), ANR-19-CE16-0025,mitoGPCR,Les récepteurs couplés aux protéines G mitochondriaux en neuroprotection(2019), Université Paris Cité, Equipe HAL, Les tanycytes transportent la leptine dans le cerveau: identification des mécanismes et rôle dans la physiopathologie de l'obésité et du diabète - - GlioShuttles4Metabolism2015 - ANR-15-CE14-0025 - AAPG2015 - VALID, Les récepteurs couplés aux protéines G mitochondriaux en neuroprotection - - mitoGPCR2019 - ANR-19-CE16-0025 - AAPG2019 - VALID

المصدر: Molecular Pharmacology
Molecular Pharmacology, 2021, 100 (4), pp.319-334. ⟨10.1124/molpharm.121.000270⟩

مصطلحات موضوعية: Male, endocrine system, G protein, Acylation, Endocytic cycle, Incretin, Pharmacology, Endocytosis, Inbred C57BL, Incretins, Glucagon-Like Peptide-1 Receptor, chemistry.chemical_compound, Mice, Downregulation and upregulation, Insulin Secretion, Functional selectivity, Animals, Humans, Cyclic adenosine monophosphate, Receptor, digestive, oral, and skin physiology, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, Mice, Inbred C57BL, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Protein Transport, HEK293 Cells, chemistry, Molecular Medicine, Exenatide, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34511d92a804b7931f16427b2792ca71Test
https://hal.science/hal-03535615/file/319.full.pdfTest