المؤلفون: Michael F. Egan, Yuki Mukai, Tiffini Voss, James Kost, Julie Stone, Christine Furtek, Erin Mahoney, Jeffrey L. Cummings, Pierre N. Tariot, Paul S. Aisen, Bruno Vellas, Christopher Lines, David Michelson

المصدر: Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: Verubecestat, BACE inhibitor, Amyloid, Alzheimer’s disease, Clinical trial, Safety, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s13195-019-0520-1Test; https://doaj.org/toc/1758-9193Test

الوصول الحر: https://doaj.org/article/b7a42dd59c2848208857c8ea93bf3567Test

المؤلفون: Tiffini Voss, James Kost, Swati Pal Mercer, Christine Furtek, Christopher Randolph, Christopher Lines, Michael F. Egan, Jeffrey L. Cummings

المصدر: Journal of Alzheimer's Disease. 92:341-348

مصطلحات موضوعية: Psychiatry and Mental health, Clinical Psychology, General Neuroscience, General Medicine, Geriatrics and Gerontology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c7ce9428f0db21e600e8044fadb63835Test
https://doi.org/10.3233/jad-220836Test

المؤلفون: Cyrille Sur, Katarzyna Adamczuk, David Scott, James Kost, Mehul Sampat, Christopher Buckley, Gill Farrar, Ben Newton, Joyce Suhy, Idriss Bennacef, Michael F. Egan

المصدر: Molecular Imaging and Biology. 24:862-873

مصطلحات موضوعية: Cancer Research, Oncology, Radiology, Nuclear Medicine and imaging

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5d3fe8c03e7e673ae78e9a53cea03dafTest
https://doi.org/10.1007/s11307-022-01735-zTest

المؤلفون: Li-Shan Huang, Christopher Cox, Philip W. Davidson, James Kost, Gary J. Myers, Christopher A. Beck, Conrad F. Shamlaye, Bernard Weiss

المصدر: Neurotoxicology. 81

مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, Child Behavior, CBCL, Food Contamination, Standard score, Toxicology, Seychelles, 03 medical and health sciences, 0302 clinical medicine, Child Development, Double-Blind Method, Pregnancy, Clinical endpoint, medicine, Animals, Humans, Prospective Studies, Adverse effect, Child, 030304 developmental biology, 0303 health sciences, business.industry, General Neuroscience, Fishes, Mercury, medicine.disease, Child development, Checklist, Prenatal Exposure Delayed Effects, Cohort, Female, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f49351bcc431dbe884515ca5e95413Test
https://pubmed.ncbi.nlm.nih.gov/35623358Test

المؤلفون: Cyrille, Sur, Katarzyna, Adamczuk, David, Scott, James, Kost, Mehul, Sampat, Christopher, Buckley, Gill, Farrar, Ben, Newton, Joyce, Suhy, Idriss, Bennacef, Michael F, Egan

المصدر: Molecular imaging and biology. 24(6)

مصطلحات موضوعية: Amyloid, Aniline Compounds, Alzheimer Disease, Positron-Emission Tomography, Humans, Brain, Amyloidosis, Polyvinyl Chloride

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::fb4d6002f57528c4375fa4550981f293Test
https://pubmed.ncbi.nlm.nih.gov/35794343Test

المؤلفون: Michael F. Egan, Saheeda Jackson, Cyrille Sur, Robert C. Sergott, James Kost, Christine Furtek, Annaswamy Raji, Amy Locco, Britta A. Mattson, Arpankumar Patel

المصدر: Journal of Alzheimer's disease : JAD. 79(1)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, genetic structures, Nerve fiber layer, Placebo, Retina, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Atrophy, Optical coherence tomography, Alzheimer Disease, Ophthalmology, medicine, Humans, Aged, Retinal pigment epithelium, medicine.diagnostic_test, Thiadiazines, business.industry, General Neuroscience, Brain, Retinal, General Medicine, Organ Size, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Cyclic S-Oxides, Psychiatry and Mental health, Clinical Psychology, 030104 developmental biology, medicine.anatomical_structure, chemistry, Brain size, Verubecestat, Female, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery, Tomography, Optical Coherence

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc9bf12a74e0f0c4b00e601d976d4aaTest
https://pubmed.ncbi.nlm.nih.gov/33252075Test

المؤلفون: David Michelson, Robert S. Stern, Christopher Randolph, Paul S. Aisen, Craig Shering, Nicole Dupre, Alette M. Wessels, Christopher Lines, James Kost, Bruno Vellas, Lyn Harper Mozley, Pierre N. Tariot, Tiffini Voss, Michael F. Egan, Christine Furtek, Yuki Mukai, John R. Sims, Jeffrey L. Cummings, Scott W. Andersen

المصدر: Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES. 16(11)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Repeatable Battery for the Assessment of Neuropsychological Status, Epidemiology, Disease, Audiology, 03 medical and health sciences, Cellular and Molecular Neuroscience, Fluency, 0302 clinical medicine, Cognition, Developmental Neuroscience, Double-Blind Method, Alzheimer Disease, medicine, Verbal fluency test, Humans, Spiro Compounds, Episodic memory, Aged, Thiadiazines, business.industry, Health Policy, Imidazoles, Cyclic S-Oxides, Clinical trial, Psychiatry and Mental health, 030104 developmental biology, Treatment Outcome, Verubecestat, Female, Neurology (clinical), Geriatrics and Gerontology, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7c442b70d759befbd7fc0eb9aa0342Test
https://pubmed.ncbi.nlm.nih.gov/33049114Test

المؤلفون: Pierre N. Tariot, James Kost, Bruno Vellas, Cyrille Sur, Matthew E. Kennedy, Tiffini Voss, Michael F. Egan, Christopher Lines, David Scott, Katarzyna Adamczuk, Yuki Mukai, Erin Mahoney, David Michelson, Jeffrey L. Cummings, Paul S. Aisen, Nick C. Fox

المصدر: Brain

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Placebo, Hippocampus, White matter, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Alzheimer Disease, Neurofilament Proteins, Internal medicine, Medicine, Dementia, Aspartic Acid Endopeptidases, Humans, Cognitive decline, Enzyme Inhibitors, Aged, Aged, 80 and over, Amyloid beta-Peptides, medicine.diagnostic_test, Thiadiazines, business.industry, Brain, Magnetic resonance imaging, Original Articles, Middle Aged, medicine.disease, Mental Status and Dementia Tests, Magnetic Resonance Imaging, White Matter, Cyclic S-Oxides, 030104 developmental biology, medicine.anatomical_structure, Diffusion Tensor Imaging, Treatment Outcome, Positron-Emission Tomography, Brain size, Cardiology, Verubecestat, Biomarker (medicine), Female, Neurology (clinical), Amyloid Precursor Protein Secretases, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a010b8e9d3bbe845dbeb7f1beaaaf4Test
https://pubmed.ncbi.nlm.nih.gov/33253354Test

المؤلفون: James Kost, Julie A. Stone, Bruno Vellas, Pierre N. Tariot, Paul S. Aisen, Erin Mahoney, David Michelson, Christine Furtek, Jeffrey L. Cummings, Yuki Mukai, Christopher Lines, Tiffini Voss, Michael F. Egan

المساهمون: Bodescot, Myriam, Merck & Co., Inc. [Kenilworth, NJ, États-Unis], Merck & Co., Inc. [North Wales, PA, États-Unis], Department of Brain Health [Las Vegas, NV, États-Unis], Lou Ruvo Center for Brain Health [Las Vegas], Cleveland Clinic-Cleveland Clinic-University of Nevada [Las Vegas] (WGU Nevada), Banner Alzheimer's Institute [Phoenix, AZ, États-Unis], University of San Diego (USD), Gérontopôle, Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Supported by MSD (Merck Sharp & Dohme Corp., a subsidiary of Merck & Co. Inc., Kenilworth, NJ, USA)., University of San Diego, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Toulouse [Toulouse], Alzheimer's Disease Research and Clinical Center [Toulouse], CHU Toulouse [Toulouse]

المصدر: Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2019)
Alzheimer's Research and Therapy
Alzheimer's Research and Therapy, 2019, 11 (1), pp.68. ⟨10.1186/s13195-019-0520-1⟩
Alzheimer's Research and Therapy, BioMed Central, 2019, 11 (1), pp.68. ⟨10.1186/s13195-019-0520-1⟩

مصطلحات موضوعية: Male, 0301 basic medicine, Neuropsychological Tests, lcsh:RC346-429, 0302 clinical medicine, Aspartic Acid Endopeptidases, Suicidal ideation, Aged, 80 and over, Sleep disorder, Thiadiazines, [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, Middle Aged, Rash, Cyclic S-Oxides, 3. Good health, Clinical trial, Treatment Outcome, Neurology, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Female, Safety, medicine.symptom, Alzheimer’s disease, Amyloid, medicine.medical_specialty, Cognitive Neuroscience, Placebo, lcsh:RC321-571, Suicidal Ideation, 03 medical and health sciences, Double-Blind Method, Alzheimer Disease, Internal medicine, medicine, Humans, EPOCH (chemotherapy), Adverse effect, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, lcsh:Neurology. Diseases of the nervous system, Aged, business.industry, Research, Verubecestat, BACE inhibitor, medicine.disease, 030104 developmental biology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Neurology (clinical), Amyloid Precursor Protein Secretases, business, [SDV.NEU.SC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8fd002174637d86cd8e9ad5af9d482Test
https://doi.org/10.1186/s13195-019-0520-1Test

المؤلفون: Yuki Mukai, Ming Xu, Julie A. Stone, Christine Furtek, Huub Jan Kleijn, Tiffini Voss, Michael F. Egan, James Kost, Nicole Dupre

المصدر: Alzheimer's & Dementia. 15

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Dependency (UML), Epidemiology, business.industry, Health Policy, Disease progression, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Clinical endpoint, Verubecestat, Neurology (clinical), Geriatrics and Gerontology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cfa85bc09097fbe950d62d7e81dd8793Test
https://doi.org/10.1016/j.jalz.2019.06.069Test