المؤلفون: Waszak, SM, Northcott, PA, Buchhalter, I, Robinson, GW, Sutter, C, Groebner, S, Grund, KB, Brugieres, L, Jones, DTW, Pajtler, KW, Morrissy, AS, Kool, M, Sturm, D, Chavez, L, Ernst, A, Brabetz, S, Hain, M, Zichner, T, Segura-Wang, M, Weischenfeldt, J, Rausch, T, Mardin, BR, Zhou, X, Baciu, C, Lawerenz, C, Chan, JA, Varlet, P, Guerrini-Rousseau, L, Fults, DW, Grajkowska, W, Hauser, P, Jabado, N, Ra, YS, Zitterbart, K, Shringarpure, SS, De La Vega, FM, Bustamante, CD, Ng, HK, Perry, A, MacDonald, TJ, Driever, PH, Bendel, AE, Bowers, DC, McCowage, G, Chintagumpala, MM, Cohn, R, Hassall, T, Fleischhack, G, Eggen, T, Wesenberg, F, Feychting, M, Lannering, B, Schuz, J, Johansen, C, Andersen, TV, Roosli, M, Kuehni, CE, Grotzer, M, Kjaerheim, K, Monoranu, CM, Archer, TC, Duke, E, Pomeroy, SL, Shelagh, R, Frank, S, Sumerauer, D, Scheurlen, W, Ryzhova, MV, Milde, T, Kratz, CP, Samuel, D, Zhang, JH, Solomon, DA, Marra, M, Eils, R, Bartram, CR, von Hoff, K, Rutkowski, S, Ramaswamy, V, Gilbertson, RJ, Korshunov, A, Taylor, MD, Lichter, P, Malkin, D, Gajjar, A, Korbel, JO, Pfister, SM

المصدر: The Lancet. Oncology. 19(6):785-798

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:138401333Test

المؤلفون: Sweha, SR, Chung, C, Natarajan, SK, Panwalkar, P, Pun, M, Ghali, A, Bayliss, J, Pratt, D, Shankar, A, Ravikumar, V, Rao, A, Cieslik, M, Wilder-Romans, K, Scott, AJ, Wahl, DR, Jessa, S, Kleinman, CL, Jabado, N, Mackay, A, Jones, C, Martinez, D, Santi, M, Judkins, AR, Yadav, VN, Qin, T, Phoenix, TN, Koschmann, CJ, Baker, SJ, Chinnaiyan, AM, Venneti, S

المساهمون: Mackay, Alan, Jones, Chris

مصطلحات موضوعية: Animals, Brain Neoplasms, Epigenesis, Genetic, Glioma, Glycine, Histones, Humans, Mice

جغرافية الموضوع: United States

وصف الملف: Print-Electronic; application/pdf

العلاقة: ARTN eabf7860; Science Translational Medicine, 2021, 13 (615), pp. eabf7860 -; https://repository.icr.ac.uk/handle/internal/6201Test

الإتاحة: https://doi.org/10.1126/scitranslmed.abf7860Test
https://repository.icr.ac.uk/handle/internal/6201Test

المؤلفون: Sturm, D, Orr, BA, Toprak, UH, Hovestadt, V, Jones, DTW, Capper, D, Sill, M, Buchhalter, I, Northcott, PA, Leis, I, Ryzhova, M, Koelsche, C, Pfaff, E, Allen, SJ, Balasubramanian, G, Worst, BC, Pajtler, KW, Brabetz, S, Johann, PD, Sahm, F, Reimand, J, Mackay, A, Carvalho, DM, Remke, M, Phillips, JJ, Perry, A, Cowdrey, C, Drissi, R, Fouladi, M, Giangaspero, F, Lastowska, M, Grajkowska, W, Scheurlen, W, Pietsch, T, Hagel, C, Gojo, J, Loetsch, D, Berger, W, Slavc, I, Haberler, C, Jouvet, A, Holm, S, Hofer, S, Prinz, M, Keohane, C, Fried, I, Mawrin, C, Scheie, D, Mobley, BC, Schniederjan, MJ, Santi, M, Buccoliero, AM, Dahiya, S, Kramm, CM, von Bueren, AO, von Hoff, K, Rutkowski, S, Herold-Mende, C, Fruehwald, MC, Milde, T, Hasselblatt, M, Wesseling, P, Rossler, J, Schuller, U, Ebinger, M, Schittenhelm, J, Frank, S, Grobholz, R, Vajtai, I, Hans, V, Schneppenheim, R, Zitterbart, K, Collins, VP, Aronica, E, Varlet, P, Puget, S, Dufour, C, Grill, J, Figarella-Branger, D, Wolter, M, Schuhmann, MU, Shalaby, T, Grotzer, M, van Meter, T, Monoranu, CM, Felsberg, J, Reifenberger, G, Snuderl, M, Forrester, LA, Koster, J, Versteeg, R, Volckmann, R, van Sluis, P, Wolf, S, Mikkelsen, T, Gajjar, A, Aldape, K, Moore, AS, Taylor, MD, Jones, C, Jabado, N, Karajannis, MA, Eils, R, Schlesner, M, Lichter, P, von Deimling, A, Pfister, SM, Ellison, DW, Korshunov, A, Kool, M

المصدر: Cell. 164(5):1060-1072

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:133038858Test

المؤلفون: Kilburn, LB, Khuong-Quang, DA, Hansford, JR, Landi, D, van der Lugt, J, Leary, SES, Driever, PH, Bailey, S, Perreault, S, McCowage, G, Waanders, AJ, Ziegler, DS, Witt, O, Baxter, PA, Kang, HJ, Hassall, TE, Han, JW, Hargrave, D, Franson, AT, Yalon Oren, M, Toledano, H, Larouche, V, Kline, C, Abdelbaki, MS, Jabado, N, Gottardo, NG, Gerber, NU, Whipple, NS, Segal, D, Chi, SN, Oren, L, Tan, EEK, Mueller, S, Cornelio, I, McLeod, L, Zhao, X, Walter, A, Da Costa, D, Manley, P, Blackman, SC, Packer, RJ, Nysom, K

المصدر: Nature Medicine (2023) (In press).

مصطلحات موضوعية: Drug development, Paediatric cancer, Phase II trials, Randomized controlled trials, Targeted therapies

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10182485/1/Hargrave_The%20type%20II%20RAF%20inhibitor%20tovorafenib%20in%20relapsed_VoR.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10182485Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10182485/1/Hargrave_The%20type%20II%20RAF%20inhibitor%20tovorafenib%20in%20relapsed_VoR.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10182485Test/

المؤلفون: Li, BK, Vasiljevic, A, Dufour, C, Yao, F, Ho, BLB, Lu, M, Hwang, EI, Gururangan, S, Hansford, JR, Fouladi, M, Nobusawa, S, Laquerriere, A, Delisle, M-B, Fangusaro, J, Forest, F, Toledano, H, Solano-Paez, P, Leary, S, Birks, D, Hoffman, LM, Szathmari, A, Faure-Conter, C, Fan, X, Catchpoole, D, Zhou, L, Schultz, KAP, Ichimura, K, Gauchotte, G, Jabado, N, Jones, C, Loussouarn, D, Mokhtari, K, Rousseau, A, Ziegler, DS, Tanaka, S, Pomeroy, SL, Gajjar, A, Ramaswamy, V, Hawkins, C, Grundy, RG, Hill, DA, Bouffet, E, Huang, A, Jouvet, A

المساهمون: Jones, Chris

مصطلحات موضوعية: MYC, PNET, PPTID, Pineoblastoma, RB, miRNA, Adolescent, Adult, Age Factors, Brain Neoplasms, Child, Preschool, Cohort Studies, Female, Humans, Infant, Male, MicroRNAs, Mutation, Pineal Gland, Pinealoma, Registries, Survival Rate, Young Adult

جغرافية الموضوع: Germany

وصف الملف: Print-Electronic; 241; application/pdf

العلاقة: Acta Neuropathologica, 2020, 139 (2), pp. 223 - 241; https://repository.icr.ac.uk/handle/internal/6203Test

الإتاحة: https://doi.org/10.1007/s00401-019-02111-yTest
https://repository.icr.ac.uk/handle/internal/6203Test

المؤلفون: Lamoureux, A-A, Fisher, M, Lemelle, L, Pfaff, E, Kramm, C, De Wilde, B, Kazanowska, B, Hutter, C, Pfister, SM, Sturm, D, Jones, D, Orbach, D, Pierron, G, Raskin, S, Drilon, A, Diamond, E, Harada, G, Zapotocky, M, Ellezam, B, Weil, AG, Venne, D, Barritault, M, Leblond, P, Coltin, H, Hammad, R, Tabori, U, Hawkins, C, Hansford, JR, Meyran, D, Erker, C, McFadden, K, Sato, M, Gottardo, NG, Dholaria, H, Nørøxe, DS, Goto, H, Ziegler, DS, Lin, FY, Parsons, DW, Lindsay, H, Wong, T-T, Liu, Y-L, Wu, K-S, Franson, AF, Hwang, E, Aguilar-Bonilla, A, Cheng, S, Cacciotti, C, Massimino, M, Schiavello, E, Wood, P, Hoffman, LM, Cappellano, A, Lassaletta, A, Van Damme, A, Llort, A, Gerber, NU, Ceruso, MS, Bendel, AE, Skrypek, M, Hamideh, D, Mushtaq, N, Walter, A, Jabado, N, Alsahlawi, A, Farmer, J-P, Abadi, CC, Mueller, S, Mazewski, C, Aguilera, D, Robison, N, O’Halloran, K, Abbou, S, Berlanga, P, Geoerger, B, Øra, I, Moertel, CL, Razis, ED, Vernadou, A, Doz, F, Laetsch, TW, Perreault, S

العلاقة: Lamoureux, A. -A., Fisher, M., Lemelle, L., Pfaff, E., Kramm, C., De Wilde, B., Kazanowska, B., Hutter, C., Pfister, S. M., Sturm, D., Jones, D., Orbach, D., Pierron, G., Raskin, S., Drilon, A., Diamond, E., Harada, G., Zapotocky, M., Ellezam, B. ,. Perreault, S. (2022). HGG-11. Clinical characteristics and clinical evolution of a large cohort of pediatric patients with primary central nervous system (CNS) tumors and tropomyosin receptor kinase (TRK) fusion. Neuro-Oncology, 24 (Supplement_1), pp.i61-i62. https://doi.org/10.1093/neuonc/noac079.226Test.; http://hdl.handle.net/11343/318287Test

الإتاحة: https://doi.org/10.1093/neuonc/noac079.226Test
http://hdl.handle.net/11343/318287Test

المؤلفون: Boisvert, M, Perera, AA, Condurat, AL, Jeang, J, Tsai, JW, Novikov, D, Zhou, K, Chacon, M, DiGiacomo, J, Kumbhani, R, Wang, D, Taylor, MD, Hansford, JR, Ludlow, L, Jabado, N, Ligon, KL, Beroukhim, R, Bandopadhayay, P, Jones, DTW

العلاقة: Boisvert, M., Perera, A. A., Condurat, A. L., Jeang, J., Tsai, J. W., Novikov, D., Zhou, K., Chacon, M., DiGiacomo, J., Kumbhani, R., Wang, D., Taylor, M. D., Hansford, J. R., Ludlow, L., Jabado, N., Ligon, K. L., Beroukhim, R., Bandopadhayay, P. & Jones, D. T. W. (2022). LGG-58. Understanding the transcriptional heterogeneity of pediatric low-grade gliomas and its implication for tumor pathophysiology. Neuro-Oncology, 24 (Supplement_1), pp.i101-i102. https://doi.org/10.1093/neuonc/noac079.369Test.; http://hdl.handle.net/11343/318234Test

الإتاحة: https://doi.org/10.1093/neuonc/noac079.369Test
http://hdl.handle.net/11343/318234Test

المؤلفون: Zwaig, M, Baguette, A, Hu, B, Johnston, M, Lakkis, H, Nakada, EM, Faury, D, Juretic, N, Ellezam, B, Weil, AG, Karamchandani, J, Majewski, J, Blanchette, M, Taylor, MD, Gallo, M, Kleinman, CL, Jabado, N, Ragoussis, J

العلاقة: pii: 10.1186/s12885-022-10359-z; Zwaig, M., Baguette, A., Hu, B., Johnston, M., Lakkis, H., Nakada, E. M., Faury, D., Juretic, N., Ellezam, B., Weil, A. G., Karamchandani, J., Majewski, J., Blanchette, M., Taylor, M. D., Gallo, M., Kleinman, C. L., Jabado, N. & Ragoussis, J. (2022). Detection and genomic analysis of BRAF fusions in Juvenile Pilocytic Astrocytoma through the combination and integration of multi-omic data. BMC Cancer, 22 (1), pp.1297-. https://doi.org/10.1186/s12885-022-10359-zTest.; http://hdl.handle.net/11343/334778Test

الإتاحة: https://doi.org/10.1186/s12885-022-10359-zTest
http://hdl.handle.net/11343/334778Test

المؤلفون: Mack, SC, Witt, H, Piro, RM, Gu, L, Zuyderduyn, S, Stütz, AM, Wang, X, Gallo, M, Garzia, L, Zayne, K, Zhang, X, Ramaswamy, V, Jäger, N, Jones, DTW, Sill, M, Pugh, TJ, Ryzhova, M, Wani, KM, Shih, DJH, Head, R, Remke, M, Bailey, SD, Zichner, T, Faria, CC, Barszczyk, M, Stark, S, Seker-Cin, H, Hutter, S, Johann, P, Bender, S, Hovestadt, V, Tzaridis, T, Dubuc, AM, Northcott, PA, Peacock, J, Bertrand, KC, Agnihotri, S, Cavalli, FMG, Clarke, I, Nethery-Brokx, K, Creasy, CL, Verma, SK, Koster, J, Wu, X, Yao, Y, Milde, T, Sin-Chan, P, Zuccaro, J, Lau, L, Pereira, S, Castelo-Branco, P, Hirst, M, Marra, MA, Roberts, SS, Fults, D, Massimi, L, Cho, YJ, Van Meter, T, Grajkowska, W, Lach, B, Kulozik, AE, von Deimling, A, Witt, O, Scherer, SW, Fan, X, Muraszko, KM, Kool, M, Pomeroy, SL, Gupta, N, Phillips, J, Huang, A, Tabori, U, Hawkins, C, Malkin, D, Kongkham, PN, Weiss, WA, Jabado, N, Rutka, JT, Bouffet, E, Korbel, JO, Lupien, M, Aldape, KD, Bader, GD, Eils, R, Lichter, P, Dirks, PB, Pfister, SM, Korshunov, A, Taylor, MD

المصدر: Nature. 506(7489)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Genetics, Pediatric, Human Genome, Rare Diseases, Animals, Brain Neoplasms, CpG Islands, DNA Methylation, Embryonic Stem Cells, Ependymoma, Epigenesis, Genetic, Epigenomics, Female, Gene Expression Regulation, Neoplastic, Gene Silencing, Histones, Humans, Infant, Mice, Mice, Inbred NOD, Mice, SCID, Mutation, Phenotype, Polycomb Repressive Complex 2, Prognosis, Rhombencephalon, Xenograft Model Antitumor Assays, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/60w365s8Test

المؤلفون: Khan, A, Gamble, LD, Upton, DH, Ung, C, Yu, DMT, Ehteda, A, Pandher, R, Mayoh, C, Hébert, S, Jabado, N, Kleinman, CL, Burns, MR, Norris, MD, Haber, M, Tsoli, M, Ziegler, DS

المصدر: urn:ISSN:2041-1723 ; Nature Communications, 12, 1, 971

مصطلحات موضوعية: Rare Diseases, Cancer, Brain Disorders, Neurosciences, Brain Cancer, 5 Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Biological Transport, Brain Stem Neoplasms, Cell Death, Cell Line, Tumor, Cell Proliferation, DNA Replication, Dicarboxylic Acid Transporters, Diffuse Intrinsic Pontine Glioma, Disease Models, Animal, Eflornithine, Female, Gene Expression Regulation, Neoplastic, Humans, Mice, Inbred BALB C, Nude, Mitochondrial Membrane Transport Proteins, Ornithine Decarboxylase, Polyamines

وصف الملف: application/pdf

العلاقة: http://purl.org/au-research/grants/nhmrc/APP1125036Test; http://hdl.handle.net/1959.4/unsworks_75636Test; https://unsworks.unsw.edu.au/bitstreams/18eccced-68d5-4616-bd06-070bec0dd64f/downloadTest; https://doi.org/10.1038/s41467-021-20896-zTest

الإتاحة: https://doi.org/10.1038/s41467-021-20896-zTest
http://hdl.handle.net/1959.4/unsworks_75636Test
https://unsworks.unsw.edu.au/bitstreams/18eccced-68d5-4616-bd06-070bec0dd64f/downloadTest