المؤلفون: Hong Soon Kang, Anton M. Jetten, Kevin Gerrish, Amir Aghajanian, Ju Youn Beak, Brian C. Jensen, Seok Jae Hong, Wei Huang, Rishi Deshmukh, Nishi Kadakia

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: HIF-1α, hypoxia-inducible factor-1α, Caveolin 3, PINK1, PTEN-induced putative kinase 1, LC3B-II, microtubule-associated protein light chain beta 3-II, Mitochondrion, Biochemistry, CMKO, cardiomyocyte-specific RORα KO, JC-1, 5, 5′, 6, 6′-tetrachloro-1, 1′, 3, 3′-tetraethylbenzimidazolylcarbocyanine iodide, Mitochondria, Heart, Mice, Mitophagy, OCR, oxygen consumption rate, Myocytes, Cardiac, Cav-3, caveolin-3, mt-Keima, mitochondrial-targeted Keima, shCtrl, scrambled shRNA, Cardioprotection, Gene knockdown, LDH, lactate dehydrogenase, Bnip3, BCL2 interacting protein 3, HRP, horseradish peroxidase, Nuclear Receptor Subfamily 1, Group F, Member 1, shRORα, shRNA against RORα, Cell biology, ChIP, chromatin immunoprecipitation, BFA1, bafilomycin A1, SDH, succinate dehydrogenase, NRVMs, neonatal rat ventricular myocytes, qRT-PCR, quantitative RT-PCR, Research Article, caveolin-3, mPTP, mitochondrial permeability transition pore, cardiomyocyte mitochondrial physiology, Biology, ROS, reactive oxygen species, Downregulation and upregulation, Animals, TEM, transmission electron microscopy, Molecular Biology, ROR, retinoic acid–related orphan nuclear receptor, Ang II, angiotensin II, hypoxia, Autophagy, Cell Biology, RAR-related orphan receptor alpha (ROR-alpha), Nuclear receptor, Hsp60, heat shock protein 60, PFA, paraformaldehyde

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cc243bde3123b1ebf3e9dc15c170f2Test
http://europepmc.org/articles/PMC8626585Test

المؤلفون: Yasuharu Shinoda, Yasushi Yabuki, Yuki Aoyama, Naoya Fukui, Hanae Yamamoto, Kohji Fukunaga, Tomohiro Mizobata, Ichiro Kawahata, Yasushi Kawata, Kunihiro Hongo, Moe Miyabe

المصدر: The Journal of Biological Chemistry
Fukui, Naoya. Yamamoto, Hanae. Miyabe, Moe. et al. An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3. Journal of Biological Chemistry. 296, 100663. 2021-04-20.

مصطلحات موضوعية: 0301 basic medicine, Thio-T, Thioflavin-T, N2a, neuro2a, Peptide, Protein aggregation, Biochemistry, Green fluorescent protein, amyloid fibrils, Mice, Neuroblastoma, MEM, minimal essential medium, Tumor Cells, Cultured, Fluorescence microscope, Cytotoxicity, CD, circular dichroism, GFP, green fluorescent protein, chemistry.chemical_classification, His6-FABP3, FABP3 with N-terminal His6 tag, synuclein-fatty acid binding protein 3 complex, QCM, quartz crystal microbalance, αSynP, synthetic peptide derived from α-synuclein, FABP3, fatty acid binding protein 3, alpha-Synuclein, JC-1, 5, 5’, 6, 6’-tetrachloro-1, 1’, 3, 3’-tetraethylbenzimidazolylcarbocyanine iodide, Intracellular, Research Article, Amyloid, MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, αSyn, α-synuclein, FRET, fluorescence resonance energy transfer, Protein Aggregation, Pathological, protein aggregation, 03 medical and health sciences, α-synuclein, FBS, fetal bovine serum, PUFA, polyunsaturated fatty acid, Animals, Humans, TEM, transmission electron microscopy, Molecular Biology, PD, Parkinson’s disease, fatty acid binding protein 3, 030102 biochemistry & molecular biology, Cell Biology, ANS, 1-anilinonaphtalene-8-sulfonate, Peptide Fragments, AFM, atomic force microscopy, 030104 developmental biology, Förster resonance energy transfer, chemistry, Biophysics, Fatty Acid Binding Protein 3

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f65c094ec9071bc126830bb84c2b90bTest
https://doi.org/10.1016/j.jbc.2021.100663Test